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관상동맥 풍선성형술 후 발생한 관상동맥 박리의 초기 조영술적 고찰
고영엽,강지인,장재혁,강민정,정중화,장경식,홍순표 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Background and Objectives: Percutaneous coronary intervention (PCI) is widely utilized in the treatment of symptomatic coronary artery disease (CAD). Althouth it has numerous benefits, intimal tear or dissection, serious and potentially life-threatening complications of plain old balloon angioplasty (POBA) can occur. The aim of this study was to assess the implications of coronary dissections after ballon angioplasty. Methods: 78 consecutive patients (age, 62 +/- 11 years; 46 men, 32 women) identified to two groups as having with or without dissection (dissection (D) group or non-dissection (ND) grouP) underwent balloon angioplsty for CAD were studied. All patients with dissection could be managed by successful stent implantation to rescue the artery. The morbidity of ischemic complication and mortality were evaluated for 30days after PCI. Results: Coronary dissection developed 44 lesions (38%) in 31 patients out of 117 lesions in 78 patients after POBA and a good final angiographic result was obtained in all patients with dissection, Significant correlates of a development of dissection were the lesion morphology of ACC/AHA type B and C (P<0.05). There were no significant correlations of clinical pictures, whether POBA in single vessel disease or in multivessel disease, diameter stenosis before POBA, and balloon/coronary artery diameter ratio. Morphologic feature of dissection was type A in 15 (34%), type B in 13(30%), type C in 12 (27%), and type D in 4 (9%). After PCI, there was no ischemic complication or death related coronary dissection during follow-up period for 30days. Conclusions: Coronary dissection after angioplasty occurred in 44 lesions (38%) out of 117 lesions of 78 consecutive patients underwent POBA. Coronary dissection after POBA significantly correlated with the severity of lesion morphology. Coronary stenting is effective in the management of acute coronary dissections after angioplasty.
이중에너지 방사선 흡수계측법을 이용한 성인 남녀의 장골 및 경골의 골밀도에 관한 연구
조용석,김경원,이경호,박현진,서상수,오상엽 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.3
Purpose : The aim of this study was to evaluate the bone mineral density of iliac and tibial bone which are frequently selected as autogenic bone graft donor sites, and to evaluate the efficiency of this method as a guideline for the selection of bone graft donor site. Materials and Methods : In this study 61 male and 70 female volunteers at Chungbuk National University Hospital were involved between Jan. 1998 to Sept. 1999. We measured bone mineral density of the iliac and the tibial bone using dual energy X-ray absorptiometry. We evaluated the data using the SAS system for Windows and bone mineral density of the lumbar was used for control. Results : Age showed the highest correlation in correlation matrix between physical and bone variables. Height and weight showed lower correlation of linear increment. In man, the change of bone density according to age demonstrated linear decrease irrespective of the lumbar, ilium, and tibia. In woman, the change of bone density according to age showed cubic form, which increased in the third and forth decade. So it had a peak bone mass on about 35 year-old, thereafter, the change of bone density slowly decreased until 50 year-old, but it rapidly decreased after 50 year-old and it slowly decreased again after 65 year-old. Both in all subjects and subject with osteoporosis, the change of bone mineral density according to age showed statistically significant decrease in lumbar and tibia, but ilium was irrespective. Conclusion : In patients of aged or with osteoporosis, ilium demonstrated less tendency of decrease in bone mineral density than tibla. So this preliminary study suggested that ilium seemed better donor site for autogenic bone graft than tibia.
Kyoung-Eun Park,Chang Youp Ok,Hye-Ock Jang,Moon-Kyoung Bae,Soo-Kyung Bae 대한구강생물학회 2020 International Journal of Oral Biology Vol.45 No.3
Resveratrol has been reported to exert anticancer activity via modulation of multiple pathways and genes. In this study, we examined the effect of resveratrol on YD-10B human oral squamous cell carcinoma cells and its molecular mechanisms of action. We found that resveratrol inhibited the proliferation of YD-10B cells in a dose- and timedependent manner. The suppressive effect of resveratrol was accompanied by a reduction in Bmi-1 gene expression. We observed that silencing the Bmi-1 gene by small interfering RNA effectively downregulated the levels of GLUT1 mRNA and protein, which were also repressed by resveratrol. Bmi-1 silencing increased the number of YD-10B cells in S-phase arrest by approximately 2.3-fold compared with the control. In conclusion, the results of the present study demonstrate, for the first time, that resveratrol suppresses Bmi-1-mediated GLUT1 expression in human oral squamous cell carcinoma cells and suggest that the specific molecular targeting of Bmi-1 and/or GLUT1 expression can be combined with a chemotherapeutic strategy to improve the response of oral cancer cells to resveratrol.
Heterogeneity of HPV DNA in a case of bowenoid papulosis which progressed to squamous ceil carcinoma
( Kyoung Chan Park ),( Kyu Han Kim ),( Jong Seong Ahn ),( Sang Woong Youn ),( Ji Hwan Hwang ),( Ki Ho Park ),( Young Gull Kim ),( Sang Duck Kim ),( Dae Youp Lee ),( Joon Ho Choe ),( Jin Ho Chung ),( K 대한피부과학회 1998 초록집 Vol.36 No.20
Park, Kyoung-Duck,Jeong, Hyun,Kim, Yong Hwan,Yim, Sang-Youp,Lee, Hong Seok,Suh, Eun-Kyung,Jeong, Mun Seok American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.3
<P>We developed a instrument consisting of an ultraviolet (UV) near-field scanning optical microscope (NSOM) combined with time-correlated single photon counting, which allows efficient observation of temporal dynamics of near-field photoluminescence (PL) down to the sub-wavelength scale. The developed time-resolved UV NSOM system showed a spatial resolution of 110 nm and a temporal resolution of 130 ps in the optical signal. The proposed microscope system was successfully demonstrated by characterizing the near-field PL lifetime of InGaN/GaN multiple quantum wells.</P>
Acute Myocardial Infarction in a Young Adult during Vigorous Physical Activity
Young Youp Koh,Young Jae Ki,Sung Soo Kim,Hyun Wook Kim,Keun Ho Park,Dong Hyun Choi,Joong Wha Jeong,Kyoung Sig Chang 조선대학교 의학연구원 2017 The Medical Journal of Chosun University Vol.42 No.4
Acute myocardial infarction (AMI) as an acute form and a catastrophic manifestation of coronary artery disease (CAD) is the major cause of morbidity and mortality worldwide. The prevalence and incidence of myocardial infarction can be influenced by demographic, biological and psychosocial factors, and it is rare in childhood and adolescent years. Contrary to the elderly, where cardiac attack is mainly caused by CAD, exercise-induced cardiac attack is relatively more prevalent in a young adult. We report here on a case of ST-segment elevation myocardial infarction (STEMI) in a young adult during vigorous physical activity and we review the relevant literatures.
Woo Jin Shin,Kyoung Youp Park,김동인,Jang Woo Kwon 한국통신학회 2009 Journal of communications and networks Vol.11 No.2
In this paper, we investigate a dynamic spectrum shar- ing problem for the centralized uplink cognitive radio networks using orthogonal frequency division multiple access. We formulate a large-scale joint rate and power allocation as an optimization problem under quality of service constraint for secondary users and interference constraint for primary users. We also suggest ad- mission control to nd a feasible solution to the optimization prob- lem. To implement the resource allocation on a large-scale, we in- troduce a notion of using the conservative factors ® and ¯ depend- ing on the outage and violation probabilities. Since estimating in- stantaneous channel gains is costly and requires high complexity, the proposed algorithm pursues a practical and implementation- friendly resource allocation. Simulation results demonstrate that the large-scale joint rate and power allocation incurs a slight loss in system throughput over the instantaneous one, but it achieves lower complexity with less sensitivity to variations in shadowing statistics.