주요 선진국의 의약품 분류 및 재분류 사례 비교

김헌식 충북대학교 의과대학 충북대학교 의학연구소 2013 忠北醫大學術誌 Vol.23 No.2

연구목적: 올바른 의약분업 시행을 위해 중요한 요소인 국내 의약품분류의 개선에 참고자료로 활용하 기 위해 주요 외국의 의약품분류 및 재분류 사례를 조사하여 우리나라 현황과 비교하고자 하였다. 대상 및 방법: 주로 비처방용 의약품들에 대한 국제적인 의약품분류 및 재분류 현황을 DB로 제공하고 있는 WSMI(world self-medication industry)에서 우리나라를 포함해 주요 9개국의 의약품분류 현 황 데이터베이스를 제공받아 비교 분석에 활용하였다. 결과: 우리나라는 비교 대상이 된 미국, 일본 등 주요 선진국에 비해 더 많은 종류의 비처방 의약품들 을 사용하고 있다. 처방약과 비처방약의 상대적 비율은 0.49로 비교 대상국 중 영국을 제외하고 가장 낮아 처방약에 비해 비처방약이 상대적으로 많은 상태에 있다. 각국의 재분류 사례를 비교한 결과, 우 리나라는 비교 대상국 중 분류전환(switch) 실적이 가장 낮은 것으로 확인되었다. 결론: 우리나라는 주요 선진국에서 사용하지 않는 불필요한 의약품들을 다수 사용하고 있으며 상대적 으로 더 많은 의약품들이 비처방약으로 분류되어 있는 것으로 평가된다. 의약품 재분류 제도의 운영도 비교 대상국들에 비해 매우 미흡한 것으로 확인되었다. 현행 의약품분류의 개선과 향후 의약품 재분류 제도의 활성화가 요구된다.

勞動時間

全憲植 淸州大學校 1967 論文集 Vol.6 No.1

朝鮮後期 燕行錄에 나타난 遼東

정훈식 부산대학교 한국민족문화연구소 2007 한국민족문화 Vol.29 No.-

This paper is aimed at reviewing various aspects of discourse on Liantong of the period through Liaotong-related text in yeonghaengnok in the latter period of Chosun Dynasty. The discourse on Looting was spread especially after Pyeongja Hoarn- Manchu's invasion in 1636-, and it was formed and developed through the yeonhaengnok. We can see three aspects in the discourse of Liaotong that was captured in Yeonhaengnok. First, It is the memorial discourse of the ancient territory. The recognition the fact that Liantong was our ancient territory was rapidly spread while Yeonhaengsa traveled through the Liaotong area. This was successfully applied to forget the disgrace of the Manatee's invasion. Secondly, It's the discourse on space of Liaotong. This focused on examination of the space meaning for the Liaotong with experience of prosperous street and vast open field. Through this effort, they had confirmed the Liaotong as the space of communication, which Chosen could be connected to the world. Lastly, It's the discourse on the history of Ming-Ching war. The discourse on finding out the origin of Liaotong's political situation was found when passed on the Ming-Ching war area. this discourse tried to find out the way of Chorine's right recognition of Liaotong political situation analyzing the reason for the shift of Ming-Ching Dynasty unlike the effort to overcome the disgrace of Manta's invasion through the memory of the ancient territory. As explained above, we confirm that the discourse of Liaotong of the latter period of Chosen Dynasty does not merely rely on the memory of the ancient territory like the one of Koguryo.

청소년과 약물문제

김헌수,유영식,나철,이철,민병근 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.3

Few literatures in the area of substance abuse in adolescent exist in Korea. Accordingly, it will be necessary to investigate the causes of substance abuse in adolescent, and practitioner must recognize the meaning of the drug abuse for the individual in his environmental and developmental context as well. Furthermore, the practitioner should be aware of the syndromes elicited by substance and differential diagnostic procedures by chemical assay or other lab findings. Effective multimodality ways of confronting issues in a therapeutic and a preventive manner must be developed, because of a component of complex and multifactor of treatment in drug abuses.

킬레이트 형성기로서 Ethylenediamine을 도입한 다공성 중공사막에 의한 금속이온의 흡착특성

김헌석,김민,이영기,김병식 동국대학교 산업기술연구원 1999 산업기술논문집 Vol.14 No.-

폐수나 초순수 중의 금속이온을 효율적으로 회수하기 위해 킬레이트 형성기로서 에틸렌디아민(EDA)을 방사선그래프트중합법에 의해 생성된 그래프트 체인에 도입하였다. 그래프트율에 따른 에틸렌디아민기의 밀도를 측정하였으며, 그래프트율 177%의 경우 4.25mol/kg으로 나타났다. 에틸렌디아민기가 도입된 중공사막의 금속이온에 대한 흡착용량은 투과법에 의해 측정되었다. 투과압력의 변화에 무관한 흡착용량을 나타내었으며, 흡착된 금속이온은 용리액에 의해 100% 용리가 되었다. 구리(Cu)와 카드뮴(Cd)의 2성분 흡착에서는 구리이온이 카드뮴이온을 치환흡착 하는 것을 알 수 있었다. An ethylenediamine(EDA)-group as a chelate forming group was appended onto a hollow fiber membrane for effective recovery of metal ion from waste water or ultra pure water by radiation-induced graft polymerization of an epoxy-group-containing monomer, glycidylmethacrylate(GMA), and subsequent chemical modification. The density of EDA-group was investigated as a function of the degree of GMA grafting(dg), and it was 4.25mol/kg in case of the dg 177%. The adsorption of metal-ion onto toe EDA-hollow fiber membrane was measured by the permeation method. The metal adsorption capacity during permeation of a copper solution through the EDA-hollow fiber at various flow rate demonstrated that a higher flow rate is not affected to the collection efficiency. In the binary adsorption of Cu^2+/Cd^2+, we could see that Cu^2+ ion was substituted for Cd^2+ ion and adsorbed finally.

동시성 공유정신병 : 일란성 쌍생아 자매의 역할반전 Case Formulation of Role Reversal

신화식,유희정,김헌수,김현실,민병근 울산대학교 의과대학 1995 울산의대학술지 Vol.4 No.1

The twin sisters case of folie simultanee is reported here in this paper. A case of folie simultanee is described as two or more people becoming psychotic simultaneously and sharing the same delusion. The results of psychodynamic approach for this case are as follows. 1. There are a variety of conflicting hypotheses on the orgin of the disorder, ranging from the etiological explanation of organic factor to various psychodynamic approach. In this case, there is no evidence of hereditary factor on the laboratory findings and family history. Therefore the authors stressed that the psychodynamic formulation of the disorder is on the importance .of the etiological rol. It seem significant to describe that the etiology is multidimensional and includes factors such as character structure formation in processing of object relations, the emotional relationship between the partners, socio-environmental conditions and hereditary predisposition. 2. There are two issues in folie simultanee. The one is related to diagnosis. It is consider to distinguish the inductor from the recipient. The other is subject to treatment. It is important to determine whether separate the inductor and recipient by admitting the inductor for a psychiatric center or not. Furthermore, the inductor and recipient's weak ego state should be recognized in planning various psychiatric treatments. 3. It could be found in the role reversal phenomenon between the inductor and recipient during long-term course.

골관절염 환자에서 관절내 Sodium Hyaluronate(Hyruan®)의 투여가 슬관절통에 미치는 영향

김훈정,임경준,위상우,정종달,유벙식,안태훈,소금영 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

Background : Sodium Hyaluronate has been found to be deficient in the synovial fluid of patients with osteoarthritis. We evaluate the effect of intraarticular Sodium Hyaluronate(Hyruan®) on the knee joint pain in patients with osteoarthritis. Method : Ten patients with osteoarthritis of the knee were participated in this study. Sodium Hyaluronate was injected into knee joints weekly for 5 weeks consecutively. Clinical evaluations were performed using visual analogue scale(VAS) for pain, tenderness and swollen joint counts weekly for the first 5 weeks and at 10 weeks postinjection. Result : VAS, tenderness and swollen joint were all significantly improved from 2 weeks to 10 weeks. There was no complication, except pain on injection site in two patients. Conclusion : Intraarticular injection of Sodium Hyaluronate has been shown to be effective on the treatment of patients with osteoarthritis of the knee.

학생청소년의 불안성향과 문제행동 유형간의 상관분석

김헌수,이재우,나철,김영돈,김민호,김은희,권지란,박광식,이길홍,민병근 중앙대학교 의과대학 의과학연구소 1987 中央醫大誌 Vol.12 No.4

The purpose of the present study was to examine the relationship between their problem behavioral pattern and anxious trends among Korean student adolescent. Zung's measurement of anxiety level undergone through used of the self-rating anxiety scale. the data were collected through the questionaire survey which was conducted on Dec.1, 1983. Subjects served for this atudy consisted of 1,404 syudents in Korea, randomly sampled from Korean student population by means of census method. The data were analysed by CDC-174 computer of KAIST, using SPSS pogram. Statistical methods empoyed were χ^2 test and Eta measures. the results of this study were as follows. 1. It showed that students psychological anxious trends had greatest significant correlation with adolescent student's problem brhavioral pattern, but the cardiovascular, respiratory, gastrointestional and genitourinary anxious trends has not significantly related with student's problem behavioral pattern. 2. Students group with undersocialized aggressive, undersocialized nonaggressive,undersocialized school-norm avoidant, or socialized nonaggressive behavioral patterns were less anxious, whereas those with socialized latent aggressive, socialized sexual, or socialized modellong behavioral patterns were higher anxious.

편측 하악 과두골절의 관혈적 치료에 있어서 예후에 영향을 줄 수 있는 인자들에 관한 임상 통계학적 연구

성현모,이동근,민승기,오승환,장관식 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.1

The purpose of this study is to reveal the factors leading to the problem of unilateral condylar fractures and suggest a treatment guideline of treatment for good prognosis in surgical treatment, The factors can be age, sex, fracture site, degree of displacement, posterior occlusion loss, post-operative alteration of condylar head position, post-operatlve condylar head resorption, and maxillomandibular fixation period. One hundred and eleven patients with unilateral condylar fractures, who were treated by surgical method from 1990 Feb. to 2000 Feb., were studied. Minimum follow-up period was 6 months. The results were as follows ; 1. In the age group of 41 ∼60, females had significantly higher complication rate than males, therefore we must be careful about treatment of female in this age group 2 In level I fractures of the mandibular condyle, because there were abundant complications when the patients were treated with fragment removal, conservative treatment is recommended over the surgical approach. 3. There were no differences in the complication rate, in the level Ⅱ, Ⅲ fractures. but were severe complications in the cases of patients treated by Dr.Nam's method or fragment removal. Therefore, open reduction and internal fixation is recommended over Dr.Nam's method or fragment removal. 4. In level Ⅳ fractures, open reduction and internal fixation is recommended 5. Although there was a higher complication rate depending on the degree of deviation, there was no correlation between the degree of deviation and development of complications in each level of fracture 6. Because the complication rate was higher in cases of condylar resorption, vertical dimension loss, and alteration of condylar head position, we must make an effort to prevent such complications during treatment

탐촉자 시스템의 처짐과 응력해석

공용식,류봉조,정훈택,박홍원 한밭대학교 생산기반기술연구소 2001 생산기반기술연구소 논문집 Vol.1 No.1

This paper deals with stress analysis and deflections for probe stage systems connected to semi-conductor apparatus. Most of the real probe stage systems are composed of three mechanical parts such as slider, X-base and Y-base. In order to calculate the maximum stress and deflection for probe stage systems, three-dimensional finite element model is applied. Numerical results are obtained by changing various design parameters related to the above three parts. Through the numerical simulation, optimal design shape satisfying von Mises yield criterion is presented. The analysis was performed by using commercial COSMOS/M FEA code.