흰쥐 대뇌피질에 분포하는 Neuropeptide Y 양성세포에 대한 면역조직화학적 연구

김대균,원무호,최월봉 대한해부학회 1992 Anatomy & Cell Biology Vol.25 No.3

신경세포 移住 異常에 의한 뇌기형의 자기공명영상

정무찬,김대호,김기정 순천향대학교 1990 논문집 Vol.13 No.1

Neuronal migrational anomalies are rare congenital malformations of the brain, and caused by interruption of normal migration of neuroblasts during the 2nd to 6th months of gestation. These anomalies include agyria/pachygyria complex, schizencephaly, heterotopia of gray matter, polymicrogyria. Six patients with migrational anomalies are evaluated by MRI. One patient has agyria/pachygyria complex anomaly, three patients have schizenceaphaly, and two patients have gray matter heterotopia. The patients have other associated anomalities, such as absence of septum pellucidum, and some have complex anomalies. MRI is better method to determine the migratory disorders than CT, because of better contrast between gray and white matter, and multiplanar capability of MRI. MRI is an excellent method for diagnosing these neuronal migrational anomalies.

초고집적 반도체 마스크 보호용 다층페리클의 투과특성개선

김대현,안무선,김필수 漢陽大學校 基礎科學硏究所 1995 基礎科學論文集 Vol.14 No.-

반도체 노광공정(photolithography)의 주 광원인 파장 436㎚(G-line) 과 365㎚(I-line)에서 최대 투과율을 가지는 마스크 보호용 광학박막 (pellicle)에 대하여 연구하였다. CaF₂-NC -CaF₂ 삼중박막에 대해 NC (nitrocellulose)막의 두께와 그 양면에 증착할 CaF₂의 두께 변화에 따른 투과율을 전산 모의실험으로 구하였다. 모의실험 결과에 따라 1.15㎛ 두께의 NC의 양면에 두께 900∼950Å인 CaF₂를 열진공증착하여 G-line 과 I-line에서 이중극대를 갖는 pellicle을 제작하였다. 삼중막 pellicle에서 이론적으로 계산된 투과율과 실험적으로 측정한 투과율을 비교한 결과 목적파장에서 최대투과점이 일치하지 않았다. 이 문제를 해결하기 위하여 두께보정인자Ft를 도입하였고, 1.15㎛ 두께 NC막에서의 Ft는 0.92로 나타났다. 전산모의 실험에서 얻은 결과에 두께보정인자를 고려하여 Gline과 I-line에서 최대투과율을 갖는 삼중 반사방지박막의 최적 제작조건을 예측할 수 있도록 하였다. An optical thin film(pellicle) for mask protecting has been studied, which has maximum transmittance at wavelengths of 436㎚(G-line) and 365㎚(I-line) of main light source in the photolithography of semiconductor process. for CaF₂-NC -CaF₂ triple layer pellicle, the transmittance was evaluated by computer simulation with two variables, the thickness of nitrocellulose(NC) film and that of CaF₂ film deposited on both sides of NC film. From the simulation result, the pellicle which has maximum transmittances at G-line and I-line was fabricated by thermal deposition of CaF₂ 900∼950Å on both sides of 1.15 ㎛ NC film. Comparing theoretically evaluated transmittance with experimentally measured transmittance for triple layer pellicle, maximum transmittance points did not coincide with G-line and I-line. To solve this problem, correction factor of thickness should be introduced. This factor gave 0.92 in 1.15㎛ NC film. Taking into account of this correction factor, an optimal fabrication condition of triple layer pellicle could be easily expected.

연골이식을 이용한 와우형 이개 기형의 교정

민대홍,김영수,백무현,김승홍 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.1

Among the congenital ear deformity, the snail shell(escargot) ear is a combined form of the lop and satyr ear, and corresponds to Tanzer's "constricted ear, group Ⅲ" and correspond to the "severe cupped" ear of Fukuda, and has been called "cucurucho"(ice-cream cone) by Malbec. Embryologically, hillocks three and four and the intervening cleft are affected, and there is severe underdevelopment of the upper ear, including the intervening anterior and superior helix, the upper scapha and scaphal fossa, superior crus and triangular fossa. The upper ear is rolled forward and downward, deviating the longitudinal axis. Correction methods of the snail shell ear were various from the Kislov method to the rib cartilage graft for radical treatment of full-blown microtia. We recently the case of a 26 years old woman who presented the lidding of the upper one third helix and corrected this deformity with the contralateral conchal cartilage graft. Thus we got the good result.

국가예방접종전산등록체계 개발을 위한 민간의료 기관 하부구조 및 환경 조사연구

이무식,김은영,이건세,이석구,홍지영,김건엽,김대경,신의철,이연경,기몽서,나백주,김영택 한국모자보건학회 2003 한국모자보건학회지 Vol.7 No.2

흉통과 생활변화, 대처행동양식 및 사회적 지지의 관계 : 관상동맥조영술을 받은 환자들을 중심으로 Focused on Patients Undergone Coronary Arteriography

정진대,국승희,이무석 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.3

본 연구는 흉통을 주소로 관상동맥조영술을 시행받은 환자 중 조영술상 양성군과 음성군, 대조군의 일반 인구학적 특성, 관상동맥질환의 관련요인, 흉통의 양상, 년간 생활변화량, 대처행동양식, 사회적 지지에 대한 지각의 차이, 기능장애정도 등을 비교하고자 하였다. 처음으로 관상동맥조영술을 시행하는 40명의 환자를 대상으로 의무기록지 검토, 반구조화된 면접, 사회재적응 평가척도, 대인관계지지 평가지, 대처행동 평가지, 기능장애 척도 등을 실시한 후 조영술 결과에 따라 양성군과 음성군으로 분류하였으며 이들과 흉통의 과거력이 없었던 정상대조군을 비교하여 살펴보았다. 요약하면 1) 음성군이 양성군에 비해 유의하게 여성이 더 많았고(p<0.05), 비전형적인 흉통을 호소하는 환자가 유의하게 많았다(p<0.01). 2) 년간생활변화량에서는 음성군, 양성군이 정상대조군에 비해 통계적으로 유의하지는 않지만 생활변화가 많았음을 알 수 있었고, 특히 건강과 관련한 생활변화량에서는 유의하게 높은 점수를 보였다(p<0.05). 3) 대처양식에 있어서는 음성군, 양성군이 소극적인 대처양식(정서완화적 대처)을 유의하게 많이 사용하였다(p<0.01). 4) 사회적 지지도는 음성군이 가장 부정적으로 지각하는 경향이었으나 유의한 차이는 없었다. 5) 기능장애에 있어서는 음성군과 양성군이 현저한 기능장애를 보였으나 두 군간에 유의한 차이는 없었다. 본 연구에서는 흉통환자에서 심리, 사회적인 면이 관여하는 것으로 나타났다. 그러나 다른 많은 연구결과에서 지적하듯 흉통을 호소하는 환자의 많은 수에서 이러한 심리적인 어려움이 있음에도 불구하고 지금까지 정신과적 진단과 치료가 제한되어 있었다. 본 연구는 흉통을 가진 환자들 특히, 관상동맥에 유의한 협착이 없으면서도 지속적인 흉통과 기능장애를 갖는 환자들에게 잘못된 대처양식의 수정과 같은 행동치료, 부정적 지각과 같은 왜곡된 인지에 대한 치료와 같은 정신과적 치료적 중재를 통해 증상의 재발방지와 재활에 도움을 줄 수 있을 것으로 기대된다. 향후 좀더 구체적인 심리적 프로그램에 대한 연구가 계속되어야 할 것으로 생각된다. The purpose of this study was to compare the life change unit, coping behaviors, percived social support, functional disability in patients who had a negative coronary arteriogram and those who had arteriographic evidence of coronary artery stenosis with the matched controls. Patients admitted for coronary arteriography to the cardiovascular department of the Chonnam University Hospital were assessed, on the day before coronary arteriography, on the psychological characteristics using self-rating scales such as Social Readjustment Rating Scale, Interpersonal Support Evaluation List, The Ways of Coping Checklist, and Functional Disability Scale. The results of comparing the psychological characteristics of groups with and without significant coronary artery stenosis and normal controls are as follows : In life change unit, patients with chest pain had significantly elevated health-related life events but no statistically significant differences in total life change. In coping behaviros, patients with chest pain were showed to have more passive coping(especially, tension-reduction coping) than normal controls. In social support, patients with chest pain and negative coronary arteriogram were the most negative cognition but there no statistically significant differences. In functional disability, patients with chest pain showed much higher functional disability score than normal controls. We recognized the relationship of psychological factors to the chest pain patients, psychological terapeutic intervention may provide prevention of symptom relapse and rehabilitation for the negative coronary arteriogram patients with persistent chest pain, and functional disability.

재활용 폐페인트를 이용한 방청페인트 개발연구

한대상,정재헌,조홍식,조창제,이종무,장상목 동아대학교 공과대학부설 생산기술연구소 1998 生産技術硏究所硏究論文集 Vol.3 No.2

In this study, The method to produce anticorrosive paint using reproductive wastepaint was investigated. The liquid-phase resin, BHO-500 and powder-phase paint BHO-300 were produced through wastepaint reproductive process. BHO-500 and BHO-300 could be replaced respectively polyvinylchloride resin and filler, which are thr components of anticorrosive paint. The properties of the anticorrosive paint produced through this process were excellent in comparison with the existing anticorrosive paint.

로자탄 대 포시노프릴의 고혈압 환자들에서 항고혈압 효과, 안전성 및 내약성의 비교

박대균,이명묵,채인호,이무용,이홍자,김효수,김철호,손대원,오병희,박영배,최윤식 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.1

생체분해성 고분자를 이용한 사시수술용 제형개발 및 효용성에 대한 연구

민병무,김용백,김승영,김창식,박근성,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A new device, muscle clamping system was developed to facilitate exact quatifying technique A strabismus surgery, and reduce the risk of complications. The device is composed of a lower fixing body with three jaws and an upper supporting body. They are used to clip an extraocular muscle and fix it to the sclera with a single bite. Superior rectus recession on 16 rabbit eyes were performed with this new device. Conjunctival injection, muscle adhesion strength, and light microscopic findings were examined at 1, 2, 4 and 8 weeks postoperatively. The Conjunctival injection were minimal, adhesion power ranged from 420 to 600 gram gravity, which is sufficient in withstand the normal pull of human extraocular muscle. In microscopic exam, some Inflammatory cells and fibrosis were found. The new device was technically easy, fast, and accurate, so it may be useful in stabismus surgery.

복막유착의 원인 규명과 예방을 위한 실험적 연구

강대영,송규상,노승무,조준식,이태용 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

Postoperative peritoneal adhesion is the most common cause of intestinal obstruction, and intestinal obstruction is one of the most difficult problems in abdominal surgery. In this experimental study for developing peritoneal adhesion model and its prevention, we divided rats into 5 groups; the talc powder treated group, the cotton-fluff treated group, the talc+fluff treated group, the ischemia group and the control group. There were 16 rats in each group. We made incisions on the midabdomen of the rats and administered talc powder, cotton fluff and talc powder+fluff into the peritoneal cavity respectively. In the ischemia group, we clamped the root of superior mesenteric artery for two minutes to induce ischemia on the small bowel of the rat. We counted the number of the peritoneal adhesive sites in peritoneal cavity on the 7th, 14th , 21st and 42nd postoperative day after peritoneal adhesion induced operation, and observed the characters of the adhesion state. The average number of the peritoneal adhesions were 1.25 per one rat in the talc powder group, 1.44 in the fluff group, 1.31 in the talc+fluff group and 1.31 in the ischemia group compared with 0.94 per one rat in the control group performed sham operation. 91.6% of the all adhesions were observed on the peritoneum of the previous incision sites and only 8.4% of the adhesions were adhered to the peritoneal surface of non-incision sites. The data of this study suggest that peritoneal injury and inflammatory reaction is the major cause of peritoneal adhesion. Also this study indicates that foreign bodies can develop peritoneal adhesion, but the effect is much lower than that of peritoneal injury with inflammatoty reaction.