Propylthiouracil에 의한 중증 급성간염 1예

임종주,심미령,이명수,김태현,오석규,안선호,박무림,김남호,박병현,조성구 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.2

PTU에 의한 간염의 발생은 매우 드물게 발생하는 것으로 알려져 있으나 저자들은 Graves씨 병으로 진단 받고 propylthiouracil 투여를 받고있던 환자에서 중증의 급성 간염이 발생한 1예를 경험하였기에 보고하는 바이다. Propylthiouracil is widely used to treat patients with hyperthyroidism. This drug has been associated with severe hepatotoxicity rarely. We presented the case of jaundice and profound liver dysfunction from a 23-year old woman treated with propylthiouracil for hyperthyroidism. Viral, metabolic, and autoimmune liver disease could be excluded and liver biopsy revealed a pattern of acute hepatitis. After discontinuing the drug, there was a progressive resolution of hepatic symptoms and decrease in biochemical data of the liver. Despite propylthiouracil induced hepatitis in rare case, patients receiving propylthiouracil are exposed to develope severe hepatotoxicity. Therefore it might be advisable to monitor level of the transaminase on regular base from patients receiving propylthiouracil.

메탈핼라이드 램프용 조도제어형 자기식 안정기의 최적 설계 방법

박종연,이현진 江原大學校 産業技術硏究所 2009 産業技術硏究 Vol.29 No.A

The inductor which is used at low frequency as the main part of magnetic ballast consists of an iron core, a bobbin and coil. The conventional inductor design method is not suitable for the magnetic ballast because it has various variables and is not a unique method for the magnetic ballast. Thus, this paper presents the optimal design method for a lamination type inductor using a magnetic ballast for Metal Halide Lamps. Also, the optimal inductor design method is researched for inductors of dimming ballasts and ignitors that have a gate-triggered structure using a SCR thyristor. By the simulation and experimental results, we showed that the proposed design methods is valid.

주변환경 방사선감시기 시스템에 관한 연구

박광현,정종은,김승연 大田産業大學校 1993 한밭대학교 논문집 Vol.10 No.2

원자력발전소내 공정계통들에서나, 핵시설 주변의 특정지역에서의 방사선누출을 감시하기 위해서 특정 지역주변 방사선 감시계통들이 설치되어져 있다. 환경오염 문제와 함께 주변환경 방사선 감시계통의 수요가 날로 증대할 것으로 예상되므로 국내에서 개발제작하기 위한 요소기술의 확보가 필요하다. 본 논문에서는, 외국업체들이 시판하고 있는 주변환경 방사선 감시계통을 조사분석하여, 채택된 기술과 장래의 발전방향이 고려된 주변환경 감시계통의 프로토타입(Prototype)을 설계·개발하였다. 개발·제작된 프로토타입에서는 평면표시소자(LCD)와 마이크로프로세서(Intel 8051 series)를 사용하여 하드웨어 부분을 구성하였으며, 소프트웨어 부분의 프로그램들은 A8051 ASM Language와 C-Language로 작성하였다. Area Radiation Monitoring Systems are installed to monitor radioative release of particular area around the nuclear facilities and process & effluent systems within the nu-clear power plants. With the environmental contamination problems, it if: expected that the need for the Environmental Radiation Monitoring System will increase in our country, and it needs to establish a generic technology for development and manufacturing of the Environ mental Radiation Monitoring System domestically. In this paper, Environmental Radiation Monitoring System(ERMS) of foreign-make which is on the market is surveyed and analyzed, and the prototype of ERMS is developed and manufactured with adopted technology by foreign country and considering of the direction of development in the future. In this prototype which is developed and manufactured, the hardware part consists of a flat display device(LCD device) and a microprocessor(Intel 8051 series), while the software part is comprised of the programs which are implemented by A8051 ASM language and C-language.

포탈모니터 설계·개발에 관한 연구

정종은,박광현,김승연 大田産業大學校 1993 한밭대학교 논문집 Vol.10 No.2

포탈모니터는 방사선 보건물리장비들중의 한 가지로서, 핵물질을 이용하는 시설들에서 작업하는 작업종사자들의 오염유무를 탐지하는데 사용하고 있다. 그러나, 현재 국내에서 사용 중인 모든 포탈모니터는 수입에 의존하고 있으므로 본 논문에서는 포탈모니터의 국산화를 위하여 수행된 설계·개발 연구를 기술하고 있다. 포탈모니터의 전체회로를 기능에 따라 모듈별로 분리하여 구성하므로써 고장수리를 용이 하게 하였으며 각 모듈간의 신호전송에 RS-422 직렬통신방식을 도입하여 감시기 구성을 간소화 시켰다. 또한 단일칩 마이크로콘트롤러의 사용으로 사용부품수를 줄였으며, 이에 따른 고장발생 확율의 감소 및 장비의 신뢰성을 증진시켰다. 이 연구를 통해 얻어진 기술과 경험은 다른 보건물리장비의 개발·제작에도 활용할 수 있을 것이다. A Portal Monitor which is one of the health physics equipment is used to monitor the contamination of workers in the nuclear facilities. But, most of all monitors in use in Korea are imported from abroad. Therefore, in this paper, results from the study on the design & development for portal monitor are described. The whole circuits of the portal monitor are divided into functional sections and designed with module type. The fabrication of the portal monitor is simplified by the adoption of RS-422 protocol to the signal communication between modules. With the adoption of one chip microcontroller, Intel 8751, as the central processing unit each module, many components are reduced and hence the possibility of malfunction could also be reduced and high reliability is obtained. The experiences and technology we have had through this study show the possibility of producing other health physics equipment.

32Watt 형광등용 3단자 반도체 스타터의 개발 및 특성

박종연,지광현,김은광 江原大學校 産業技術硏究所 1997 産業技術硏究 Vol.17 No.-

Various types of electronic starter have been developed for the general fluorescent lamps with magnetic-type ballasts. However, the FL032/T8 fluorescent lamp requires higher voltage to discharge the lamp. The general starter with two-terminal is not suitable for the FL032/T8 slim-line type fluorescent for its higher discharge voltage. The suitable starter with three terminals have been studied for the FL032/T8 lamp in this paper. The developed starter have better characteristics in view points of the discharge voltage magnitude. We have proposed and designed the three terminals electronic starter. The proposed starter have been experimented and compared with the other 2-terminal general starters. By the experimental results, we have concluded that the proposed starter is suitable to the FL032/Ts lamp.

광양만의 저질 중금속 농도 분포 특성

김도희,유한홍,정종성,조현서,신현출 木浦海洋大學校 2002 論文集 Vol.10 No.1

The main goals of the study were to investigate the sediment quality and trace metal distribution in sediment of Kwangyang Bay, south coastal of Korea. Surface sediment sampling were performed in November, 2000 and February and March, 2001. The concentration of H₂S, IL and COD in sediment were measured by a manual of the Department of Marine Environment of Korea. The extracted trace metals Fe, Cu, Cd, Pb, and Zn in sediments mean analyzed by the flame atomic absorption spectrophotometer with an instrument of model Shimadzu AA-6701F. H₂S, IL and COD in the surface sediment were 1.3 mg/g, 5.9 % and 15.0 mg/g, respectively. The mean content of Fe, Cu, Cd, Pb and Zn were 1523 mg/kg, 4.799 mg/kg, 1.321 mg/kg 9.285 mg/kg and 9.353 mg/kg, respectively. All of these measured trace metals level were over the other reported trace metal level in sediment of coastal area. According to histograms, the content of H₂S, IL and COD and trace metals in sediment of this study were affected by artificial activities rather than natural process.

遠隔制御用컴퓨터인터페이스에 관한 硏究

송철,박종백,이웅기,이강현,양원일 조선대학교 동력자원연구소 1988 動力資源硏究所誌 Vol.10 No.1

This paper deals with the computer interface for the remote control in factory automation, and the concatenated IBM PC, designed interface card, temperature sensors and displayer. As the results 1. easy to expand and maintain the objects of upgrade levels. 2. easy to measure the temperature of product lines. 3. applications can be extended by using IBM PC and its function.

METRx™ 기구를 이용한 후방 경추부 추궁추간공 제거술의 예비 결과

박형천,윤승환,박종운,하윤,현동근,김은영,박현선,임대철 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

Objectives: Posterior cervical microscopic laminoforaminotomy has been a preferred procedure for a posterolateral cervical disc or foraminal stenosis. However, neckpain from wide skin incision and muscle injury are some of disadvantages. The authors performed cervical microscopic laminoforaminotomy with METRx™ tubular dilator system and were compared the results with classical cervical microscopic foraminotomy. Methods: Six patients underwent posterior cervical microscopic laminoforaminotomy using the METRx™ during 6 months. We have selected 10 patients from our institution as a comparison group. Preoperative and postoperative pain score composed of the radicular and neck component was examined and disability score also recorded. Diameters and lengths of laminoforaminotomy on the postoperative CT also were compared with two methods Results: Postoperative pain scores to the radiculopathies were not different but postoperative pain scores to the neckpain on the follow up periods were significantly different. The average vertical and transverse diameters of the laminoforaminotomy defect on the postoperative CT scans were not different between two groups. Average hospital stay of the classical methods was 8.8±7.5 days comparison with 4.5±0.54days of new procedure. Conclusions: Posterior cervical microscopic laminoforaminotomy with METRx™ systems seems to provide similar decompression and clinical results as classical methods compared to classical methods and shows superior results for postoperative neckpain and hospital stays.

전형적인 DISIDA scan 소견의 Rotor 증후군 1예

황의태,염동한,권지혜,임종주,최창수,김태현,김학철 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

만성의 비용혈성 직접형 고빌리루빈혈증은 Rotor 증후군과 Dubin-Johnson 증후군의 특징적인 소견으로, Rotor 증후군은 드문 양성 유전성 질환이며, Dubin-Johnson 증후군과 감별을 필요로 한다. 본 저자들은 황달을 주소로 내원한 26세 남자 환자에서 고빌리루빈혈증에 대한 검사를 시행하여 담도폐쇄 소견없이 간담도 스캔상 전형적인 Rotor 증후군의 소견 즉, 강한 심장 배후방사능이 지속되면서, 간담도계의 조영은 지연 촬영에서도 관찰되지 않으며 신장으로의 배설이 계속 관찰되는 특징적인 소견과 정상 간조직 검사 결과로 Rotor 증후군으로 진단한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Chronic nonhemolytic conjugated hyperbilirubinemia characterizes both Rotor and Dubin-Johnson syndromes. Rotor syndrome is a rare, benign familial disorder and needs to be differentiated from Dubin-Johnson syndrome. Cholescintigraphy is a simple and informative procedure for the diagnosis, which can differentiate Rotor syndrome from Dubin-Johnson syndrome. A 26-year-old man was admitted due to asymptomatic persistent jaundice. Physical examination revealed icteric sclera without hepatosplenomegaly. Laboratory findings showed increased serum bilirubin with direct bilirubinemia. Markedly decreased hepatic uptake and poor visualization of the gallbladder and biliary tract were shown in ^(99m)Tc-DISIDA scan. Histology of the liver showed no diagnostic abnormality without pigmentation. But, we report a case of Rotor syndrome that showed characteristic cholescintigraphic findings with normal urinary total coproporphyrin excretion.

전신성홍반성루푸스 환자에서 발생한 순수어농

김윤정,김해림,박시내,윤종현,이상헌,박성환,김호연 대한내과학회 2004 대한내과학회지 Vol.66 No.4

순수어농이란 발성언어에 대한 이해와 반복에 장애를 보이지만 읽기, 쓰기, 비발성언어에 대한 이해는 보존되는 경우를 일컫는다. 저자들은 45세 루푸스 환자에서 루푸스 혈관염으로 인해 일차 청각 피질을 포함한 왼쪽 관자이랑에 뇌경색이 발생하여 초래한 순수어농 1예를 경험하였기에 보고하는 바이다. Pure word deafness is characterized by an impairment of auditory comprehension and repetition of speech while a preservation of reading, writing, spontaneous speech and ability to comprehend non-verbal sounds. It is caused by trauma, infection in the temporal lobe of brain. In most cases, the lesions are bilateral, in the middle third of superior temporal gyri, but in a few cases unilateral lesions of dominant temporal lobe are localized. We experienced a case of 45 year-old right handed wonman with systemic lupus erythemato년 (SLE) who presented pure word deafness after left temporal lobe infarction including primary auditory center. Her comprehension was impaired, while reading and visual comprehension were normal. Audiometric tests and auditory evoked potentials disclosed no hearing defect. Brain MRI showed a left temporal lobe infarction without abnormal vascular finding in MRA. She wasdiagnosed as pure word deafness due to SLE vasculitis and managed with high dose steroid and cyclophosphamide therapies.