타액선의 다형성 선종에서 발견한 암종의 세침흡인 세포학적 소견 -5 예 보고-

최현주,김활웅,함의근,박인애,Choi, Hyun-Joo,Kim, Hwal-Woong,Ham, Eui-Keun,Park, In-Ae 대한세포병리학회 2001 대한세포병리학회지 Vol.12 No.2

Carcinoma ex pleomorphic adenoma(CXPA) is a rare malignant tumor of the salivary gland, fine needle aspiration cytology(FNAC) of which are rarely reported. We retrospectively reviewed FNAC of five cases of histologically proven CXPA of the salivary glands diagnosed in Seoul National University Hospital to evaluate their cytologic characteristics. Histologically, the carcinoma components were low-grade in three cases and high-grade in two cases. The cytologic diagnosis were malignancy in two cases(40%), suspicious for malignancy in one(20%), and benign(pleomorphic adenoma) in two(40%). All of the high-grade carcinomas were correctly diagnosed by FNAC, however, 2 cases of low-grade carcinomas were diagnosed as benign by FNAC. The low sensitivity in cytologic diagnosis is due to interpretative difficulties in low-grade tumors. The characteristic cytologic features of CXPA were high cellularity, necrotic, bloody, and inflammatory background, marked nuclear overlapping, coarsely granular chromatin, prominent macronucleoli, and atypical mitosis in epithelial component in addition to the typical biphasic pattern of pleomorphic adenoma consisting of epithelial cells admired with spindle-shaped cells and chondromyxoid stroma. Even though low-grade tumors show mild pleomorphism, the cytologic findings of necrotic background, moderate to high cellularity, and nuclear overlapping could lead to an accurate cytodiagnosis of CXPA.

자궁경부 세포도말 검사에시 미세침윤성 편평세포암종의 세포학적 분석

최현주,박인애,Choi, Hyun-Joo,Park, In-Ae 대한세포병리학회 2001 대한세포병리학회지 Vol.12 No.1

Whlie cytologic characteristics of squamous dysplasia, carcinoma in situ, and invasive squamous cell carcinoma of the uterine cervix are well documented, relatively few studios have dealt with the cellular features of microinvasive carcinoma. In order to describe the cellular characteristics of microinvasive squamous cell carcinoma, we retrospectively reviewed 45 cervovaginal smears(15 carcinoma in situ, 15 microinvasive cancer, 15 invasive cancer) which were confirmed by histologic examination of specimens obtained by hysterectomy at the Seoul National University Hospital during S years from 1995 to 1999. The cytologic features about tumor diathesis, inflammatory background, ceil arrangement, anisonucleosis, nuclear membrane irregularity, nuclear chromatin pattern, and nucleoli were observed. The cytologlc characteristics of microinvasive squamous cell carcinoma of the uterine cervix are syncytial pattern, mild tumor diathesis, the irregularity of nuclear membrane, irregularly distributed nuclear chromatin, and occurrence of micronucleoli. But, correlation between the depth of Invasion and the cytologic feature had limited value.

자궁경부 Adenoma Malignum의 세포학적 소견 - 1예 보고 -

최현주,김영신,이교영,강창석,심상인,Choi, Hyun-Joo,Kim, Young-Shin,Lee, Kyo-Young,Kang, Chang-Suk,Shim, Sang-In 대한세포병리학회 1998 대한세포병리학회지 Vol.9 No.2

Adenoma malignum is an extremely well-differentiated variant of cervical adenocarcinoma in which the cells composing the tumor lack the typical cytological features of malignancy. The prognosis of this rare tumor is poor in spite of high degree of differentiation. The cytologic characteristics are extremely bland so frequently make a confusion of adenoma mailgnum with endocervical glandular hyperplasia. We report a case of adenoma malignum in a 35-year-old woman who complained of mucoid vaginal discharge and vaginal bleeding. The cervicovaginal smear showed endocervical cells exhibiting a spectrum of atypical chances. The cells were arranged in multilayered strips and monolayered sheets. Individual cells ranged from cuboidal to columnar; typically the columnar cells had abundant lacy or vacuolated cytoplasm. The smear showed the majority of only atypical cells and small numbers of frankly malignant cells.

지루 피부염 환자의 피지 조성에 관한 연구

최현주,임성빈,이승헌 ( Hyun Joo Choi,Sung Bin Lim,Seung Hun Lee ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.6

N/A We attempted to examine the compositions of seborrheic lipids from the scalp of the human adult males and the patints who have the seborrheic dermatitis by the ?hin layer chromatography(TLC) and the photodensitometer. The human skin surface lipids are composed of the seborrheic lipids from the sebaceous glands and epidermal lipids from the ediermis. The sebaceous lipids were known that they played the role to protect the skin and they had the pathophysiologic role in the seborrheic dermatitis and the ance. We observed that the sebacous lipids were composed of squalene, ??olestrol ester, wax ester, triglyceride, free fatty acid, and saturated hydrocabon in both the control group and the patient group. In the mean values of the ratio of the seborrheic lipids composition, the ratio of squalene and cholesterol eater were higher, and the ratio of free fatty acid and triglyceride were lower in the patient group than in the control group, and the ratio of wax ??ster which was originated from sebaceous glands was no difference between two groups. Thus, n?the seborrheic dermatitis, there was no change in the sebum secertion rate, but the lipid compositions were changed.

집합 결합과 신경망을 이용한 복합질환의 예측

최현주,김승현,위규범,Choi, Hyun-Joo,Kim, Seung-Hyun,Wee, Kyu-Bum 한국정보처리학회 2008 정보처리학회논문지B Vol.15 No.4

복합질환은 다수의 유전자들이 상호작용하여 유발되는 질병으로서, 여러 유전자들이 관여한다는 복잡성 때문에 전통적인 분석 방법을 적용하는데 한계가 있다. 최근에는 기계학습 기법을 이용한 새로운 분석 방법들이 제안되고 있다. 신경망은 이처럼 복잡한 데이터에서 일정한 패턴을 찾아 이를 분류하는데 적합한 모델이다. 그러나 다량의 데이터가 입력으로 들어오는 경우에 학습에 오랜 시간이 걸리고 패턴을 찾기가 어려워지는 단점이 있다. 본 연구에서는 다량의 SNP 데이터로부터 질병에 연관된 소수의 중요 SNP을 찾기 위한 통계학적인 방법인 집합결합(set association)과 신경망을 결합한 모델을 제시한다. 이 모델을 천식 관련 SNP 데이터에 적용하여 천식 발병 여부를 예측한 결과, 신경망만 사용했을 때보다 실행 시간도 빠르고 예측 정확도도 높았다. 이 모델은 다른 복합질환의 예측에도 효과적으로 사용할 수 있을 것으로 기대한다. Since complex diseases are caused by interactions of multiple genes, traditional statistical methods are limited in its power to predict the onset of a complex disease. Recently new approaches using machine learning techniques are introduced. Neural nets are a suitable model to find patterns in complex data. When large amount of data are fed into a neural net, however, it takes a long time for learning and finding patterns. In this study we suggest a new model that combines the set association, which is a statistical technique to find important SNPs associated with complex diseases, and neural network. We experiment with SNP data related to asthma to test the effectiveness of our model. Our model shows higher prediction accuracy and shorter execution time than neural net only. We expect our model can be used effectively to predict the onset of other complex diseases.

유방의 침윤성 미세유두암종의 세침흡인 세포검사

최현주,정지한,신정하,민기옥,강석진,이교영,유진영,Choi, Hyun-Joo,Jung, Ji-Han,Shin, Jung-Ha,Min, Ki-Ouk,Kang, Seok-Jin,Lee, Kyo-Young,Yoo, Jin-Young 대한세포병리학회 2007 대한세포병리학회지 Vol.18 No.1

Invasive micropapillary carcinoma (IMPC) of the breast is recently described rare variant of invasive ductal carcinoma. This variant has a distinctive histological features and aggressive biological behavior. We reviewed the cytologic features of eight cases of IMPC. The cytologic smears showed moderate to high cellularity and the tumor tissue was composed of atypical, angulated, cohesive clusters of neoplastic cells with a papillary to tubuloalveolar architecture, and a morular growth pattern without fibrovascular cores was seen on the histopathology. IMPC of the breast has distinctive cytologic features and it is important to make an early diagnosis via fine needle aspiration cytology due to this tumor's aggressive behavior.

중등학교 여학생 교복에 생활한복 도입을 위한 화생선호도 조사연구

최현주(Choi. Hyun-Joo),조효순(Cho. Hyo-Soon) 한복문화학회 1999 韓服文化 Vol.2 No.1

The study is involved in developing the Saenghwal-Hanbok or Korean traditional dothes adopting the modern style as the student uniform through referring the changing history of the school uniform after the reform age and discovering the character and the good points of the Hanbok or Korean traditional clothes. For this study, it was curried out to survey the students' preference about Hanbok, Saenghwal Hanbok, the school uniform now wearing, and the Hanbok School uniform. The result is fallowing. Rrst, the Hanbok's market diffusion is under hoping, it is mean that the Hanbok have not been used for the clothes commonly Second, the Saenghwal-Hanbok's market diffusion is under hoping, as like as Hanbok, but there are many good points over the Hanbok as everyone know. So we can look forward to a bright future with establishing planning of good sales. Third, as for the satisfaction of the school uniform now wearing, the Samhyun girl high school students give a higher value comparing with others And the last, the student's preference for the Git or the collar of the Hanbok is toward Dangko-Git and Duenggulre-Git, for cloths and a color is toward soft and temperate, and for the method of the Munyang is toward the Jasu. So, the following can be suggested to developing the Saenghwal-Hanbok as the student uniform for each site As for government's policy, they need to support the development and sales of Saenghwal-Hanbok as the student uniform in the part of the campaign of loving the our culture As for Design, they need to develop and discover our traditional cloths, Munyang and design with soft, temperate, and with beautiful lines for practical use, functional use.<br/> <br/>

이청준 소설에 드러난 금기와 용서의 아포리아

최현주 ( Hyun Joo Choi ) 현대문학이론학회 2016 現代文學理論硏究 Vol.0 No.64

언표화된 담론의 질서로서의 금기의 기원과 기능을 한국소설사에서 일찍부터 포착해낸 이가 바로 소설가 이청준이다. 이청준 소설의 주요한 탐구대상은 한국 현대사회에서 작동하는 금기의 생성과 조직, 배치와 재생산에 대한 것들이었다. 그는 현실 공간에서 당대의 지배 권력과의 직접적 투쟁의 형태가 아니라 간접화된 문화양식으로서의 소설쓰기를 선택하여 현실 권력과의 가시적인 대결이 아니라 보다 근원적인 언어혹은 예술의 장에서 치열하게 금기와의 싸움을 수행해나갔다. 이청준 문학이 금기에의 저항과 쟁투였다고 한다면 그러한 금기와의 싸움은 언어와 담론의 질서에 대한 치밀한 탐구로부터 출발하였다. 즉 그의 소설이 언어로부터 시작해서 언어로 끝난다는 발화는 이청준 소설의 경계와 지평을 제대로 표상해주는 것이기도 하다. 이러한 그의 언어에 대한 집요한 탐구는 언어사회학 연작뿐만 아니라 그의 모든 작품에서 반복적으로 변주된다. 결국 이청준은 자본주의 사회의 폭력성을 극복할 대안으로 언어를 매개로 한 소설 혹은 예술을 상정하고 미적 근대성을 구현하려했다. 이청준의 예술가 소설이 지향한 것은 패배와 복수, 주인과 노예의 변증법을 넘어서는 것이었다. 그것의 궁극은 예술을 매개로 한 시대와의 화해와 용서였다. 그런 점에서 예술가소설에 나오는 패배한 예술가들은 타락한 시대에 대한 패배자로서의 복수를 지향한 것이 아니었다. 근대 사회의 금기 체계에 저항하기 위한 거점으로서 예술의 세계를 발견했던 이청준이 직접적인 대결과 저항이 아닌 화해와 용서로 나아간 점은 어떤 개념과 직관으로도 포착하기 어려운, 하나의 객관적인 총합으로 환원되지 않는다는점에서 아포리아적이다. It was the novelist Lee Cheong-jun that grasped the origin and functions of taboo as the order of locutionary discourse early in the novel history of Korea. In his novels, he focused his inquiry on the creation, organization, arrangement and reproduction of taboos that were working in modern Korean society. Instead of engaging in direct struggle with the ruling power of the times in real space, he chose to write a novel as an indirect style of culture and had fierce fights against taboos in the more fundamental linguistic or artistic venues rather than visible face-off with the real power. His literature presented his resistance and struggle with taboos, and his fights against taboos began with his minute inquiry into the orders of language and discourse. That is, the saying "Lee``s novels start and end with language" represents the boundaries and horizons of his works correctly. His persistent inquiry into language was in repeating variations across all of his works as well as the series Sociolinguistics. In the end, he introduced language-mediated novel or art as an alternative to overcome the violence of capitalist society and tried to embody aesthetic modernity. In his artist novels, he was oriented toward a place beyond the dialectic between defeat and revenge and between the master and slave. Its ultimate point was reconciliation and forgiveness with an era via art. In that aspect, the failing artists in his artist novels did not seek evenge as losers in the degenerate days. Lee, who discovered the world of art as a base of resistance against the taboo system of modern society, moved toward reconciliation and forgiveness rather than direct confrontation and resistance, which is some sort of aporia in that it is difficult to grasp with any concept and intuition and cannot be reduced to a single objective sum.

패션쇼 관람만족에 영향을 미치는 패션쇼구성요인에 관한 연구

최현주 ( Hyun Joo Choi ),신영옥 ( Young Ok Shin ) 한국패션비즈니스학회 2008 패션 비즈니스 Vol.12 No.1

The purpose of this study is to identify how the components of a fashion show can influence the perception of the spectators, and what the spectators most like in a fashion show. Through the analysis on the literature reviews and in-depth interviews with professional`s organizing fashion shows we established a list of the main components, which allowed us to set up a questionnaire. The results regarding the viewing satisfaction of the spectators at a fashion show were investigated and came out as follows: First, the components of fashion show are generally viewed to be four factors: the program, the directing, the model, and the sets. These four factors are influencing the perception of the spectators and are very important to the success of a fashion show and the enjoyment of a fashion show by spectators. Second, it is shown to us that the most influential factor for the perception is `the directing`(stage scenery, background music, lighting, effects etc.), and the next is `the sets`(convenience seat, display, service facilities etc.). So, in order to raise the level of satisfaction for the spectators, it is advisable to concentrate on these two main factors. Finally, we would suggest that the organizer of a fashion show shall carefully analyze how spectators understand and perceive the components of a fashion show. This study provides information about how the components of a fashion show can influence the spectator`s perception and presents suggestions on how to improve a fashion show by reorienting it towards the satisfaction of the spectator. In addition, there needs to be a strategy by customer satisfaction experience to reinforce a customer-oriented fashion show and heighten a viewing satisfaction for spectators.

컨벤션 웹사이트 품질과 지각된 신념, 사용자 만족간의 영향관계

최현주(Choi, Hyun-Joo),김주연(Kim, Ju-Yeon) 한국관광레저학회 2011 관광레저연구 Vol.23 No.7