Non-Contrast Cine Cardiac Magnetic Resonance Derived-Radiomics for the Prediction of Left Ventricular Adverse Remodeling in Patients With ST-Segment Elevation Myocardial Infarction

A Xin,Liu Mingliang,Chen Tong,Chen Feng,Qian Geng,Zhang Ying,Chen Yundai 대한영상의학회 2023 Korean Journal of Radiology Vol.24 No.9

Objective: To investigate the predictive value of radiomics features based on cardiac magnetic resonance (CMR) cine images for left ventricular adverse remodeling (LVAR) after acute ST-segment elevation myocardial infarction (STEMI). Materials and Methods: We conducted a retrospective, single-center, cohort study involving 244 patients (random-split into 170 and 74 for training and testing, respectively) having an acute STEMI (88.5% males, 57.0 ± 10.3 years of age) who underwent CMR examination at one week and six months after percutaneous coronary intervention. LVAR was defined as a 20% increase in left ventricular end-diastolic volume 6 months after acute STEMI. Radiomics features were extracted from the oneweek CMR cine images using the least absolute shrinkage and selection operator regression (LASSO) analysis. The predictive performance of the selected features was evaluated using receiver operating characteristic curve analysis and the area under the curve (AUC). Results: Nine radiomics features with non-zero coefficients were included in the LASSO regression of the radiomics score (RAD score). Infarct size (odds ratio [OR]: 1.04 (1.00–1.07); P = 0.031) and RAD score (OR: 3.43 (2.34–5.28); P < 0.001) were independent predictors of LVAR. The RAD score predicted LVAR, with an AUC (95% confidence interval [CI]) of 0.82 (0.75–0.89) in the training set and 0.75 (0.62–0.89) in the testing set. Combining the RAD score with infarct size yielded favorable performance in predicting LVAR, with an AUC of 0.84 (0.72–0.95). Moreover, the addition of the RAD score to the left ventricular ejection fraction (LVEF) significantly increased the AUC from 0.68 (0.52–0.84) to 0.82 (0.70–0.93) (P = 0.018), which was also comparable to the prediction provided by the combined microvascular obstruction, infarct size, and LVEF with an AUC of 0.79 (0.65–0.94) (P = 0.727). Conclusion: Radiomics analysis using non-contrast cine CMR can predict LVAR after STEMI independently and incrementally to LVEF and may provide an alternative to traditional CMR parameters.

Preparation of activated carbon spheres and their electrochemical properties as supercapacitor electrode

An Xin,Xing Guannan,Wang Jing,Tian Yanhong,Liu Yunfang,Wan Qiong 한국탄소학회 2021 Carbon Letters Vol.31 No.4

The carbon spheres (CSs) synthesized by an ultrasonic-spray pyrolysis method were activated for supercapacitor electrode. There are plenty of cracks on the surface of the activated carbon spheres (ACSs), which expend with increasing the activation temperature and activator dosage. The specifc capacitance of ACSs increases with the activation temperature and activator dosage and reach to maximal value at certain conditions. Importantly, the ACS sample activated at relatively low activation temperature (600 °C) and 7 of mass ratio of KOH to CSs has the highest specifc capacitance (about 209 F g−1 at 50 mA g−1 of current density) and indicates the excellent cycling stability after 1000 consecutive charge–discharge cycles. Furthermore, the graphene sheets could be found in the samples that were activated at 1000 °C. And the electrode prepared by the sample has the very low series resistance because of the excellent conductivity of the formed graphene sheets.

Study on the transition wavelengths and oscillator strengths of the 1s2n′g–1s2nh state of the Li-like system

Liu Xin,Zhang Jingchao 한국물리학회 2023 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.82 No.2

In this paper, the spectral properties of 1s2 n′g–1s2 nh states of Li-like ions with larger atomic numbers (Z=21–32) are studied. The transition wavelengths of 1s2 5g–1s2 nh states from Sc XIX to Ge XXX are calculated. The dipole transition oscillator strengths of 1s2 n′g–1s2 nh confguration for Li-like ions under the three specifcations of length, velocity, and acceleration have been obtained. It is found that the three simulation results obtained are very consistent. For the transition of 1s2 5g–1s2 nh state, the dipole transition length oscillator strengths basically remain unchanged with increasing atomic number. The value of the transition oscillator strengths under the same Rydberg sequence decreases with increasing main quantum number n of the fnal state, and gradually tends to zero. Thus, the theoretical calculation of the oscillator strengths of the Li-like sequence with a higher atomic number in the entire energy threshold range is realized.

Quantum defects of 1s2nh configurations in Li-like system from Sc XIX to Zn XXVIII ion

Liu Xin,Zhang Jingchao 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.80 No.12

In this paper, the calculated ionization potential by the R-matrix method is compared with that by the full-core-plus-correlation (FCPC) method, which can verify the accuracy of the wave function. The quantum defects of the Rydberg series of the 1s2 nh states from Sc XIX to Zn XXVIII ions are calculated by the R-Matrix method. The quantum defect function of the 1s2 nh channel is obtained by theoretical calculation with the R-Matrix method. The quantum defects and highly excitated energies of high Rydberg states of the 1s2 nh states for lithium-like ions are calculated. Thus the reliable theoretical prediction of energies and quantum defects for the high Rydberg state of lithium-like ions is realized.

Progress in Adsorption-Enhanced Hydrogenation of CO2 on Layered Double Hydroxide (LDH) Derived Catalysts

Xin Fang,Chuang Chen,He Jia,Yingnan Li,Jian Liu,Yisong Wang,Yanli Song,Tao Du,Liying Liu 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.95 No.-

It is acknowledged as a promising strategy to reduce excessive CO2 emissions by catalytic conversion tovalue-added chemicals, in which layered double hydroxide (LDH) derived catalysts play essential roles. Inthe present review, latest progresses were summarized to gain insights on this issue. LDH-derivedcatalysts can be prepared via various methods and possess favorable characteristics of reversibletopotactic transformation for further development. Compared to conventional catalysts, they showspecific advantages in specific surface area, metal element dispersion and active site distribution. Despiteof distinguished LDH-derived catalysts applied in CO2 reduction reactions to methane, methanol,hydrocarbons, etc., state-of-art LDH-derived catalysts consisted of catalyst-adsorbent synergistic systemare recently constructed to employ the surface CO2 adsorption boundary layer to increase the CO2 partialpressure near active sites for hydrogenation. The overall catalytic performance is thus promoteddramatically. Accordingly, the strategy of adsorption-enhanced hydrogenation is expected to facilitatethe industrialization of CO2 hydrogenation and is instructive for catalyst design in future.

Turn off the gun

Xin Liu 한국콘텐츠학회 2019 한국콘텐츠학회 ICCC 논문집 Vol.2019 No.12

Invisible violence

Xin Liu 한국콘텐츠학회 2020 ICCC International Digital Design Invitation Exhib Vol.2020 No.11

Short-course Versus Long-course Preoperative Radiotherapy plus Delayed Surgery in the Treatment of Rectal Cancer: a Meta-analysis

Liu, Shi-Xin,Zhou, Zhi-Rui,Chen, Ling-Xiao,Yang, Yong-Jing,Hu, Zhi-De,Zhang, Tian-Song Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

Background: Short-course preoperative radiation (SCRT) with delayed surgery was found to increase pathologic complete response (pCR) rates in several trials. However, there was no clear answer on whether SCRT or long-course chemo-radiotherapy (LCRT) is more effective. Therefore we conducted this meta-analysis to evaluate the safety and efficacy of SCRT versus LCRT, both with delayed surgery, for treatment of rectal cancer. Materials and Methods: The literature was searched from PubMed, EMBASE, Web of Science, Cochrane Library and clinicaltrials.gov up to November, 2014. Quality of the randomized controlled trials (RCTs) was evaluated according to the Cochrane's risk of bias tool of RCT. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to rate the level of evidence. Review Manager 5.3 was employed for statistical analysis. Pooled risk ratios (RRs) and 95% confidence intervals (CIs) were calculated. Results: Three RCTs, with a total of 357 rectal cancer patients, were included in this systematic review. Metaanalysis results demonstrated there were no significantly differences in sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate. Compared with SCRT, LCRT was associated with significant increase in the pCR rate [RR=0.49, 95%CI (0.31, 0.78), P=0.003]. Conclusions: In terms of sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate, SCRT with delayed surgery is as effective as LCRT with delayed surgery for management of rectal cancer. LCRT significantly increased pCR rate compared with SCRT. Due to risk of bias and imprecision, further multi-center large sample RCTs were needed to confirm this conclusion.

Clinical Prognostic Factors in 86 Chinese Patients with Primary Myelodysplastic Syndromes and Trisomy 8: A Single Institution Experience

Xin-Yue Liu,Qing-Fang Yue,Lei Chen,Xiao-Mei She,Bin Hu,Yu Hu,Ping Zou 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.2

Purpose: The objective was to determine the characteristics and prognostic factors of 86 Chinese patients with trisomy 8 aberrationsand compare the prognostic value of International Prognostic System (IPSS) and Revised IPSS (IPSS-R) in this cohort. Materials and Methods: A total of 86 cases diagnosed with primary myelodysplastic syndromes (MDS) with isolated tr8 or with tr8 and other additional cytogenetic aberrations diagnosed and treated at the Union Hospital, Tongji Medical College of Huazhong University of Science and Technology between July 2002 and March 2013 were reviewed. Results: The median survival of the entire group was 23.0 months, and acute myeloid leukemia (AML) developed in 43% (37/86) patients within the follow up time. The univariate analysis revealed that overall survival (OS) was correlated with age, thrombocytopenia,absolute neutrophil count, marrow blasts, cytogenetic status and red blood cell transfusion at diagnosis, and the multivariateanalysis revealed that age, marrow blasts, cytogenetic status and transfusion dependence were independent parameters for the OS. The cytogenetic complexity and marrow blasts had the strongest impact on the AML transformation by multivariate analysis. Comparing the two prognostic systems, both two systems could successfully discriminate risk groups for survival. IPSS-R was more refined than IPSS for predicting OS, but had no advantage in predicting the risk of AML development. Conclusion: This study confirmed the influence of clinical factors on the prognosis of 86 Chinese MDS patients with trisomy 8. In addition, IPSS-R can further refine prognostic discrimination in the IPSS risk categories.

Batch Auditing for Multi-client Dynamic Data in Multi-cloud Storage

Xin Liu,Yujia Jiang 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6

Cloud storage introduces many challenges due to the security and integrity threats toward user’s outsourced data. Many auditing protocols have been proposed, but the majority of them could only serve in single cloud environment. This paper proposes an efficient auditing protocol, which supports batch auditing for multiple data files in multi-cloud environment. By utilizing the bilinear map, the proposed protocol achieves full stateless and transparent verification. By constructing a Merkle Hash Tree, the proposed protocol can resist the replace attack and support dynamic operation of data. In addition, our protocol protects the position information of the data blocks by generating fake data blocks to confuse the organizer. The performance analysis demonstrates the efficiency of the protocol.