Non-Contrast Cine Cardiac Magnetic Resonance Derived-Radiomics for the Prediction of Left Ventricular Adverse Remodeling in Patients With ST-Segment Elevation Myocardial Infarction

A Xin,Liu Mingliang,Chen Tong,Chen Feng,Qian Geng,Zhang Ying,Chen Yundai 대한영상의학회 2023 Korean Journal of Radiology Vol.24 No.9

Objective: To investigate the predictive value of radiomics features based on cardiac magnetic resonance (CMR) cine images for left ventricular adverse remodeling (LVAR) after acute ST-segment elevation myocardial infarction (STEMI). Materials and Methods: We conducted a retrospective, single-center, cohort study involving 244 patients (random-split into 170 and 74 for training and testing, respectively) having an acute STEMI (88.5% males, 57.0 ± 10.3 years of age) who underwent CMR examination at one week and six months after percutaneous coronary intervention. LVAR was defined as a 20% increase in left ventricular end-diastolic volume 6 months after acute STEMI. Radiomics features were extracted from the oneweek CMR cine images using the least absolute shrinkage and selection operator regression (LASSO) analysis. The predictive performance of the selected features was evaluated using receiver operating characteristic curve analysis and the area under the curve (AUC). Results: Nine radiomics features with non-zero coefficients were included in the LASSO regression of the radiomics score (RAD score). Infarct size (odds ratio [OR]: 1.04 (1.00–1.07); P = 0.031) and RAD score (OR: 3.43 (2.34–5.28); P < 0.001) were independent predictors of LVAR. The RAD score predicted LVAR, with an AUC (95% confidence interval [CI]) of 0.82 (0.75–0.89) in the training set and 0.75 (0.62–0.89) in the testing set. Combining the RAD score with infarct size yielded favorable performance in predicting LVAR, with an AUC of 0.84 (0.72–0.95). Moreover, the addition of the RAD score to the left ventricular ejection fraction (LVEF) significantly increased the AUC from 0.68 (0.52–0.84) to 0.82 (0.70–0.93) (P = 0.018), which was also comparable to the prediction provided by the combined microvascular obstruction, infarct size, and LVEF with an AUC of 0.79 (0.65–0.94) (P = 0.727). Conclusion: Radiomics analysis using non-contrast cine CMR can predict LVAR after STEMI independently and incrementally to LVEF and may provide an alternative to traditional CMR parameters.

Preparation of activated carbon spheres and their electrochemical properties as supercapacitor electrode

An Xin,Xing Guannan,Wang Jing,Tian Yanhong,Liu Yunfang,Wan Qiong 한국탄소학회 2021 Carbon Letters Vol.31 No.4

The carbon spheres (CSs) synthesized by an ultrasonic-spray pyrolysis method were activated for supercapacitor electrode. There are plenty of cracks on the surface of the activated carbon spheres (ACSs), which expend with increasing the activation temperature and activator dosage. The specifc capacitance of ACSs increases with the activation temperature and activator dosage and reach to maximal value at certain conditions. Importantly, the ACS sample activated at relatively low activation temperature (600 °C) and 7 of mass ratio of KOH to CSs has the highest specifc capacitance (about 209 F g−1 at 50 mA g−1 of current density) and indicates the excellent cycling stability after 1000 consecutive charge–discharge cycles. Furthermore, the graphene sheets could be found in the samples that were activated at 1000 °C. And the electrode prepared by the sample has the very low series resistance because of the excellent conductivity of the formed graphene sheets.

Evaluation of insecticidal activity of the essential oil of Allium chinense G. Don and its major constituents against Liposcelis bostrychophila Badonnel

Xin Chao Liu,Xiao Nan Lu,Qi Zhi Liu,Zhi Long Liu 한국응용곤충학회 2014 Journal of Asia-Pacific Entomology Vol.17 No.4

Water-distilled essential oil from the dried bulbs of Allium chinense (Liliaceae) was analyzed by gaschromatography–mass spectrometry (GC–MS). Eighteen compounds, accounting for 98.4% of the total oil,were identified and the main components of the essential oil of A. chinense were methyl allyl trisulfide(30.7%), dimethyl trisulfide (24.1%), methyl propyl disulfide (12.8%) and dimethyl disulfide (9.6%) followed bymethyl allyl disulfide (3.4%) and methyl propyl trisulfide (3.6%). The essential oil exhibited contact toxicityagainst the booklice (Liposcelis bostrychophila) with an LC50 value of 441.8 μg/cm2 while the two major constituents,dimethyl trisulfide and methyl propyl disulfide had LC50 values of 153.0 μg/cm2 and 738.0 μg/cm2 againstthe booklice, respectively. The essential oil of A. chinense possessed strong fumigant toxicity against the booklicewith an LC50 value of 186.5 μg/l while methyl allyl trisulfide (LC50=90.4 μg/l) and dimethyl trisulfide (LC50=114.2 μg/l) exhibited stronger fumigant toxicity than methyl propyl disulfide (LC50= 243.4 μg/l) and dimethyldisulfide (LC50= 340.8 μg/l) against the booklice. The results indicated that the essential oil and itsmajor constituentshave potential for development into natural insecticides or fumigants for control of insects in stored grains.

WILL STRONG RETAILERS ACQUIRE BETTER PROCUMENT PERFORMANCE?: ANALYSIS BASED ON THE MEDIATING EFFECT OF THE QUALITY OF RETAILER-SUPPLIER RELATIONSHIP

Wenchao Liu,Rupan Sun,Xin Xin,Lihui Sun 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7

Due to the continuous development of international retailers in the Chinese market, and the merger and reorganization among Chinese retailers in recent years, the degree of concentration of the Chinese retail industry has been increasing, and the scale of retailers has been expanding. It is suggested by the report China Powers of Retailing 2014 that an increasing number of large-scale retail groups have been formed in the Chinese retail industry. In large and medium-sized cities in China, such large-scale supermarkets as Wal-Mart, Carrefour and RT-Mart have controlled most market shares of food and daily necessities. And large-scale household appliance chains, such as Gome and Suning, have controlled most market shares of home appliance. Due to the advantage of scale and brand of large-scale retailers, these retailers have gradually occupied a leading role in the supply chain, and formed buyer monopoly power and countervailing power. Intuitively speaking, retailers can acquire obvious advantages in procurement activities, no matter it is the buyer monopoly power or countervailing power that is being utilized. And the advantages are beneficial to the improvement of retailers’ procurement performance. However, it is pointed out by a number of scholars’ research that buyer power’s influence on retail enterprises’ performance is quite complicated. Whether buyer power can improve economic efficiency depends on the quality of retailer-supplier relationship. The quality of the relationships between retailers and suppliers exerts direct influence on the stability, durability and equity of the trade. In the long term, the reinforcement of buyer power will probably exert adverse influence on the suppliers and retailers. By imposing influence on suppliers with buyer power, retailers will cause twisted competition and prifit shrinkage to suppliers in the upstream market. As a result, the quantity of suppliers will be decreased, which will be disadvantageous to the selection of retailers and affect retailers’ utilization of their negotiating advantage. In the meanwhile, by imposing special prices and discounts, collecting extra charges and signing exclusive agreement with suppliers, retailers will lead to suppliers’ impaired benefit. It will further affect the quality of the retailer-supplierrelationship and ultimately exert adverse influence on both parties’ long-term earnings. In the existing research, few scholars have thoroughly discussed the influence of retailers’ buyer power on the quality of retailer-supplier relationship and retail enterprises’ procurement performance. In addition, different conclusions exist in the analysis of the relationships among the three factors, or between two of them. In order to empirically test the influence of retailers’ buyer power on the quality of retailer-supplier relationship and retail enterprises’ procurement performance, we established the theoretical model of this study in figure 1. The research will help us to cognize the influence of retailers’ buyer power more reasonably, and guide retailers better utilize buyer power, an attempt is made to explore the following questions in this research: 1. Does direct positive influence exist between large-scale retailers’ buyer power and retailers’ procurement performance? 2. Are there any differences in the influence of different types of retailers’ buyer power on retailers’ procurement performance? 3. What influence will large-scale retailers’ buyer power exert on the quality of retailer-supplier relationship? 4. When the quality of retailer-supplier relationship is brought in as a mediating variable, what influence will large-scale retailers’ buyer power exert on retailers’ procurement performance? From the perspective of the relationships among channel members, large-scale retailers in the Chinese market, such as Wal-Mart, Carrefour, RT-Mart, OUYA Supermarket and Vanguard, as well as suppliers of their products are taken as the object of the research. Methods like interview, pre-survey and official survery with questionnaire are adopted to verify different hypotheses in the research. During the indepth interview, twelve respondents are invited respectively to the interview. Seven of them are in charge of large-scale retailers’ procurement, and five of them are salespersons of manufacturers, who supply products to retailers. It can be seen from the result of the interview that the twelve respondents hold different opinions towards the relationships among large-scale retailers’ buyer power, the quality of retailer-supplier relationship and retailers’ procurement performance. In terms of the influence of large-scale retailers’ buyer power on retailers’ procurement performance, some believe that there’s positive influence, some believe there’s negative influence, and some believe the influence should be respectively analyzed according to the degree of buyer power. In terms of the influence of large-scale retailers’ buyer power on the quality of retailer-supplier relationship, some believe large-scale retailers’ buyer power exerts positive influence on the quality of retailer-supplier relationship, some believe it exerts negative influence, and some believe the influence depends on specific circumstances. During the pre-survey with questionnaire, scales of retailers’ buyer power, the quality of retailer-supplier relationship and retailers’ procurement performance are developed on the basis of theoretical overview and interview research. Specifically speaking, the scale of retailers’ buyer power is constituted of two level-1 dimensions (buyer’s monopoly power and countervailing power) and seven level-2 dimensions; the scalerelationship and ultimately exert adverse influence on both parties’ long-term earnings. In the existing research, few scholars have thoroughly discussed the influence of retailers’ buyer power on the quality of retailer-supplier relationship and retail enterprises’ procurement performance. In addition, different conclusions exist in the analysis of the relationships among the three factors, or between two of them. In order to empirically test the influence of retailers’ buyer power on the quality of retailer-supplier relationship and retail enterprises’ procurement performance, we established the theoretical model of this study in figure 1. The research will help us to cognize the influence of retailers’ buyer power more reasonably, and guide retailers better utilize buyer power, an attempt is made to explore the following questions in this research: 1. Does direct positive influence exist between large-scale retailers’ buyer power and retailers’ procurement performance? 2. Are there any differences in the influence of different types of retailers’ buyer power on retailers’ procurement performance? 3. What influence will large-scale retailers’ buyer power exert on the quality of retailer-supplier relationship? 4. When the quality of retailer-supplier relationship is brought in as a mediating variable, what influence will large-scale retailers’ buyer power exert on retailers’ procurement performance? From the perspective of the relationships among channel members, large-scale retailers in the Chinese market, such as Wal-Mart, Carrefour, RT-Mart, OUYA Supermarket and Vanguard, as well as suppliers of their products are taken as the object of the research. Methods like interview, pre-survey and official survery with questionnaire are adopted to verify different hypotheses in the research. During the indepth interview, twelve respondents are invited respectively to the interview. Seven of them are in charge of large-scale retailers’ procurement, and five of them are salespersons of manufacturers, who supply products to retailers. It can be seen from the result of the interview that the twelve respondents hold different opinions towards the relationships among large-scale retailers’ buyer power, the quality of retailer-supplier relationship and retailers’ procurement performance. In terms of the influence of large-scale retailers’ buyer power on retailers’ procurement performance, some believe that there’s positive influence, some believe there’s negative influence, and some believe the influence should be respectively analyzed according to the degree of buyer power. In terms of the influence of large-scale retailers’ buyer power on the quality of retailer-supplier relationship, some believe large-scale retailers’ buyer power exerts positive influence on the quality of retailer-supplier relationship, some believe it exerts negative influence, and some believe the influence depends on specific circumstances. During the pre-survey with questionnaire, scales of retailers’ buyer power, the quality of retailer-supplier relationship and retailers’ procurement performance are developed on the basis of theoretical overview and interview research. Specifically speaking, the scale of retailers’ buyer power is constituted of two level-1 dimensions (buyer’s monopoly power and countervailing power) and seven level-2 dimensions; the scaleof the quality of retailer-supplier relationship is constituted of three level-1 dimensions (cooperation, adaption and relationship atmosphere); the scale of retailers’ procurement performance is constituted of three level-1 dimensions (cost performance, time performance and quality performance of procurement). The questionnaire pre-survey is specific to retailers’ procurement staff and suppliers’ sales personnel respectively. A total of valid 179 questionnaires are collected, among which, 86 are from retailers’ procurement staff and 93 are from suppliers’ sales personnel. Based on the survey data, SPSS and AMOS software are utilized in the analysis of items, reliability and validity of the different scales. Finally, the factor structure of the scale regarding retailers’ buyer power is adjusted, and the scale regarding retailers’ buyer monolopy power is re-designed specially. During the official survey with questionnaire, questionnaires are handed out to retailers’ procurement staff and suppliers’ sales personnel respectively. A total of 340 valid questionnaires are collected, among which, 178 are from retailers’ procurement staff and 162 are from suppliers’ sales personnel. The samples, which are quite representative, are evenly distributed. Based on the survey data, SPSS and AMOS software are utilized to further analyze the reliability and validity of the different appraisal scales. Finally, the various hypotheses in the research are tested by causual steps of regression analysis with SPSS. After relatively complicated and elaborate statistical analysis, most of the hypotheses are supported, some are partially supported, and only one is not supported. One of the mediating effect analysis results is show in table 1 and figure 2. Based on direct regression analysis, we can get some important results: First of all, the hypothesis that retailers’ buyer power will overally exert positive influence on retailer enterprises’ procurement performance is supported, but the hypothesis that retailers’ buyer monopoly power and countervailing power will exert positive influence on retailer enterprises’ procurement performance is partially supported. Secondly, the hypothesis that retailers’ buyer power will overally exert negative influence on the quality of retailer-supplier relationship is not supported, and the hypothesis that retailers’ buyer monopoly power will exert negative influence on the quality of retailer-supplier relationship and the dimension is partially supported, and the hypothesis that retailers’ buyer countervailing power will exert positive influence on the quality of retailer-supplier relationship and the dimension is supported. Thirdly, the hypothesis that the quality of retailer-supplier relationship, as well as the dimensions (cooperation and relationship atmosphere) will overally exert positive influence on retailer enterprises’ procurement performance is supported, and the hypothesis that the dimension---the adaptation of the quality of retailer-supplier relationship will exert positive influence on retail enterprises’ procurement performance is only partially supported. Based on causual steps of regression analysis for the mediating effect, we can also get some important results: First of all, the relationship quality plays a complete intermediary role between the retailer’s buyer power and the procurement performance. Secondly, the relationship quality plays a complete intermediary role between the r retailers’ buyer monopoly power and the procurement performance. Thirdly, the relationship quality plays a complete intermediary role between the r retailers’ buyer countervailing power and the procurement performance.Some inspirations are achieved from the research. First of all, basically speaking, the direct influence of retailers’ buyer power on retail enterprises’ procurement performance is significantly positive. Secondly, the influence of retailers’ buyer power on the quality of retailer-supplier relationship is relatively complicated. Thirdly, basically speaking, the influence of the quality of retailer-supplier relationship on retail enterprises’ procurement performance is significantly positive. Fourthly, after the quality of retailer-supplier relationship is brought in as a mediating variable, the influence of retailers’ buyer power on retail enterprises’ procurement performance depends on the specific condition of the retailer-supplier relationship.

Quantum defects of 1s2nh configurations in Li-like system from Sc XIX to Zn XXVIII ion

Liu Xin,Zhang Jingchao 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.80 No.12

In this paper, the calculated ionization potential by the R-matrix method is compared with that by the full-core-plus-correlation (FCPC) method, which can verify the accuracy of the wave function. The quantum defects of the Rydberg series of the 1s2 nh states from Sc XIX to Zn XXVIII ions are calculated by the R-Matrix method. The quantum defect function of the 1s2 nh channel is obtained by theoretical calculation with the R-Matrix method. The quantum defects and highly excitated energies of high Rydberg states of the 1s2 nh states for lithium-like ions are calculated. Thus the reliable theoretical prediction of energies and quantum defects for the high Rydberg state of lithium-like ions is realized.

Local Passive Warming Administered During the Transition Phase Impairs Subsequent Isokinetic Exercise Performance

Xin Liu,허찬솔 한국운동생리학회 2022 운동과학 Vol.31 No.2

PURPOSE: Performing a warm-up prior to a sports competition is essential for preventing injuries and maximizing subsequent performance. Passive warming has therefore received attention because it can effectively maintain an elevated muscle temperature (Tm) after a warm-up. The present study aimed to investigate the effects of local passive warming (LPW) administered during the transition phase between active warm-up and isokinetic exercises. METHODS: Eleven healthy men participated in this randomized crossover study. During the 30-minutes transition period, a customized water-perfused warming pad was placed on the anterior thighs of the dominant legs (+3°C or +6°C based on the baseline skin temperature) or no intervention for the control group (CON). Subsequently, the total work, peak torque, and average power during isokinetic knee extensions (10 repetitions at a speed of 60°/sce) were measured. Using surface electromyography (EMG), the root mean square and mean frequency from the rectus femoris during knee extension were measured to assess neuromuscular activity. RESULTS: Total work (+6°C 1289.8±389.3 vs. CON 1437.3±408.2Nm, p=.042), peak torque (+6°C 146.0±33.3 vs. CON 162.9±37.9Nm, p=.022), and average power (+6°C 77.7±19.8 vs. CON 90.2±25.3 W, p=.012) were lower in the LPW +6°C group than in the CON group. EMG RMS was lower in the LPW +6°C group than in the CON group (+6°C 58.4±22.3 vs. CON 78.6±33.0 % MVC, p=.005). MF was higher in the LPW +6°C group than in the CON group (+6°C 87.5±12.4 vs. CON 81.4±11.0 Hz, p=.016). CONCLUSIONS: Local passive warming administered during the transition phase was not an appropriate strategy for boosting the performance of subsequent isokinetic exercises. Accordingly, the application of passive warming should be carefully chosen before exercise commences

Identification and Mapping of a Thermo-Sensitive Genic Self-Incompatibility Gene in Maize

Xin Ge Lin,Hui Ling Xie,Zhang Ying Xi,Yan Min Hu,Guang Yuan Zhao,Liu Jing Duan,Zong You Hao,Zong Hua Liu,Ji Hua Tang 한국유전학회 2009 Genes & Genomics Vol.31 No.3

In this study, we describe a novel ecological self-incompatibility (SI) line HE97 in maize. The main environmental factors influencing the inbred line characteristics were identified through field sowing trials during a two-year study period (2001 and 2002). The results showed that daily minimum temperature had the greatest effect on floral morphology and breeding system of the SI line. In staminate floret differentiation, when the daily minimum temperature exceeded 24℃, the line exhibited complete self-compatibility; however SI was observed when the daily minimum temperature was below 20℃. Therefore, we characterized the line as exhibiting thermo-sensitive genic self-incompatibility (TGSI). A set of F2 and F2:3 populations, derived from the inbred lines HE97 and Z58, were evaluated for two years to elucidate the TGSI line patterns of inheritance. Classical genetic analyses and QTL mapping results revealed that HE97 self-incompatibility was governed by a single allele, named here as tgsi1. The tgsi1 gene was mapped to chromosome 2 between SSR markers nc131 and bnlg1633, with a distance of 2.40 cM from nc131 and 2.44 cM from bnlg1633.

Batch Auditing for Multi-client Dynamic Data in Multi-cloud Storage

Xin Liu,Yujia Jiang 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6

Cloud storage introduces many challenges due to the security and integrity threats toward user’s outsourced data. Many auditing protocols have been proposed, but the majority of them could only serve in single cloud environment. This paper proposes an efficient auditing protocol, which supports batch auditing for multiple data files in multi-cloud environment. By utilizing the bilinear map, the proposed protocol achieves full stateless and transparent verification. By constructing a Merkle Hash Tree, the proposed protocol can resist the replace attack and support dynamic operation of data. In addition, our protocol protects the position information of the data blocks by generating fake data blocks to confuse the organizer. The performance analysis demonstrates the efficiency of the protocol.

Sputum Metabolomic Profiling Reveals Metabolic Pathways and Signatures Associated With Inflammatory Phenotypes in Patients With Asthma

Liu Ying,Zhang Xin,Zhang Li,Oliver Brian G,Wang Hong Guang,Liu Zhi Peng,Chen Zhi Hong,Wood Lisa,Hsu Alan Chen-Yu,Xie Min,McDonald Vanessa,Wan Hua Jing,Luo Feng Ming,Liu Dan,Li Wei Min,Wang Gang 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.4

Purpose: The molecular links between metabolism and inflammation that drive different inflammatory phenotypes in asthma are poorly understood. We aimed to identify the metabolic signatures and underlying molecular pathways of different inflammatory asthma phenotypes. Methods: In the discovery set (n = 119), untargeted ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) was applied to characterize the induced sputum metabolic profiles of asthmatic patients with different inflammatory phenotypes using orthogonal partial least-squares discriminant analysis (OPLS-DA), and pathway topology enrichment analysis. In the validation set (n = 114), differential metabolites were selected to perform targeted quantification. Correlations between targeted metabolites and clinical indices in asthmatic patients were analyzed. Logistic and negative binomial regression models were established to assess the association between metabolites and severe asthma exacerbations. Results: Seventy-seven differential metabolites were identified in the discovery set. Pathway topology analysis uncovered that histidine metabolism, glycerophospholipid metabolism, nicotinate and nicotinamide metabolism, linoleic acid metabolism as well as phenylalanine, tyrosine and tryptophan biosynthesis were involved in the pathogenesis of different asthma phenotypes. In the validation set, 24 targeted quantification metabolites were significantly expressed between asthma inflammatory phenotypes. Finally, adenosine 5′-monophosphate (adjusted relative risk [adj RR] = 1.000; 95% confidence interval [CI] = 1.000–1.000; P = 0.050), allantoin (adj RR = 1.000; 95% CI = 1.000–1.000; P = 0.043) and nicotinamide (adj RR = 1.001; 95% CI = 1.000–1.002; P = 0.021) were demonstrated to predict severe asthma exacerbation rates. Conclusions: Different inflammatory asthma phenotypes have specific metabolic profiles in induced sputum. The potential metabolic signatures may identify therapeutic targets in different inflammatory asthma phenotypes.

Infection of tomato by Tomato Yellow Leaf Curl Virus alters the foraging behavior and parasitism of the parasitoid Encarsia formosa on Bemisia tabaci

Xin Liu,Yanyan He,Wen Xie,Qingjun Wu,Youjun Zhang,Yong Liu,Shaoli Wang 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.2

Encarsia formosa Gahan is a solitary endoparasitoid that is commercially reared and released for augmentative biological control of whiteflies including Bemisia tabaci (Gennadius). Bemisia tabaci biotypes B and Q are two most invasive species that greatly reduce crop yields in China by feeding on plant sap and by transmitting Tomato Yellow Leaf Curl Virus (TYLCV). The effects of TYLCV infection of tomato on E. formosa foraging on B. tabaci B and Q are unknown. In Y-tube olfactometer assays in the present study, E. formosa significantly preferred TYLCVinfected tomato plants over TYLCV-free plants. The wasp females also significantly preferred TYLCV-infected tomato plants infested with 3rd-instar nymphs of B. tabaci biotype Q over TYLCV-free plants with biotype Q nymphs. However, no significant differences were observed when B. tabaci biotype B was infested on tomato plants. The oviposition bioassays confirmed that TYLCV infection on tomato plants resulted in the recruitment of parasitoids. These results indicate that TYLCV-infection of tomato increase the foraging of E. formosa on B. tabaci, as differs on the B and Q biotypes.