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김형환,조수인,이용태,김인락 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2
The immune response is dependent on phagocyte function. When this function is deficient or enhanced, the patient is susceptable to a large variety of disease. Enhanced function results in an over active immune response. This study was carried out to investigate whether water extracts of Sijunzi-Tang and Radix Glycyrrhizae have inhibitory effect of neutrophil superoxide generation and cell injury. Superoxide was generated by rabbit polymorphonuclear leukocytes (neutrophils) stimulated by tert-butylhydroperoxide(t-BHP), and was measured by luminol and its detector chemiluminometer. The inhibitory effect of extracts against t-BHP induced superoxide generation was dose-dependent in the range of 0.1~1% concentrations. Cell injury was estimated by measuring lactate dehydrogenase(LDH), and lipid peroxidation was examined by measuring malondialdehyde(MDA), a product of lipid peroxidation. When rat renal cortical slices were treated I mM t-BHP, water decocted herbs inhibited LDH release from the slices as partially dose depecdent manner. It shows that herbs can reduce cytotoxicity, but over dose can be toxic to the slices. And MDA measurement shows the effect of Sijunzi-Tang and Radix Glycyrrhizae inhibiting cytotoxicity from oxidants, partially depend on preventing lipid peroxidation of cells. HPLC data shows the antioxidative effect of Sijunzi-Tang depends on the effect of Radix Glycyrrhizae. So further studies should be followed to make clear the mechanisms of antioxidative effects.
척추경 나사못을 이용한 척추 유합술에서 고정범위에 따른 인접 추간판의 압축 거동 분석
안면환,안종철,이수호,정일섭,이춘열,이장우 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.2
요추부 척추에 기구를 시술한 유한요소 복합체 모델을 이용하여 제 4-5 요추간판에 대한 해석을 수행한 결과, 근육의 작용을 케이블과 케이블 가이드로써 단순화 모사한 follower 하중에서 수직하중인 경우보다 높은 압축력을 나타내어 더욱 안정함을 보였고 불안정성의 원인이 되는 전단력과 굽힘모멘트의 발생은 미미하였다. 장분절 고정에 의한 인접 분절에 전단력이 증가됨을 실험적으로 보였는데, 이는 장분절 고정이 퇴행성 변화 촉진에 기여할 것으로 추정된다. Background: Confirm the stability of intervertebral disc sustaining each fused lumbar spine cases, comparing vertical compression, A-P shear force and rotational moment on intervertebral disc of instrumented lumbar spine with simple vertical compression load and follower load using finite element analysis. Materials and Methods: We analyze the stability of intervertebral disc L4-5 supporting fused lumbar spine segments. After performing finite element modelling about L1-L5 lumbar vertebral column and L1-L4 each fusion level pedicle screw system for fused lumbar spine fine element model. Intervertebral discs with complex structure and mechanical properties was modeled using spring element that compensate stiffness and tube-to-tube contact element was employed to give follower load. Performing geometrical non-linear analysis. Results: The differences of intervertebral disc L4-5 behavior under the follower compression load in comparision with vertical compression load are as follows. Conclusion: As a result of finite element interpretation of interpretation of instrumented lumbar spine, the stability of L4-5 sustaining fused lumbar segment, the long level fused lumbar spine observed hing stability under follower load. This research method can be the basis tool of effects prediction for instrumentation, a invention of a more precious finite element interpretation model which consider the role of muscle around the spine is loaded.
멕시코와 네팔에서 도입한 고추 유전자원의 풋마름병 및 역병 저항성
고보환,김정훈,전수경,이지선,김병수 慶北大學校 農業科學技術硏究所 2005 慶北大農學誌 Vol.23 No.-
Above 130 accessions of pepper consisting of 50 introductions from Mexico and Nepal, and resistant and susceptible controls were tested for resistance to bacterial wilt and to Phytophthora root rot at seedling stage by artificial inoculation. As the results, KC897, KC939, KC936 were newly found resistant to bacterial wilt in addition to already known resistance sources such as KC126, KC350, KC351, KC353. No new sources of resistance to Phytophthora root rot were found among the introductions from Mexico and Nepal.
한길영,이동기,최병기,오환교,신용욱,전수영 조선대학교 에너지.자원신기술연구소 1999 에너지·자원신기술연구소 논문지 Vol.21 No.2
Using conventional textile techniques such as weaving, braiding, knitting and stitching it is possible to produce a wide range two and three dimensional fiber preforms. However, so far only a limited attention has been given to knitted fabrics in composite industry. This is mainly due to the opinion that knitted fabric reinforced composites posses low mechanical properties owing to their looped fiber architecture. But it is possible to obtain desired mechanical properties by selecting proper knitted fabric structure. In this paper, tensile failure load and displacement of one yarn, four yarns and knitted fabrics of ten yarns of kevlar fiber were determined experimentally in the unidirection. Mechanical properties of plain weft knitted fabrics reinforced composite intrusion beam for car side door application were investigated experimentally, which compared with desire value of American Fedral Motor vehicles Safety Standard (FMVSS) and presented the results.
RO 및 NF막에서의 부식질에 의한 Fouling 및 미량오염물질의 제거
왕창근,차준철,이용현,김수동,류주환 대한상하수도학회 2004 상하수도학회지 Vol.18 No.1
This study investigated the phenomena of membrane fouling by NOM and the effect of the fouling on removal of micro-pollutants. NOM has a great effect on decline of permeate flux. Permeate flow rate was reduced by 88% in RO and 34.8% in NF for 323hr operation period. Removal rate of UV_(254), is 87.4% in RO and 78.5% in NF and removal rate of DOC is 42.7% in RO and 32.9% in NF for 2㎎/l humic acid. Removal efficiency of the micmpollutants by the RO and NF membranes fouled by humic acid was mostly lower than that by the new membrane. The concentration polarization which affects the flux and the rejection was thought to occur in the active layer of the membrane, as the membrane was getting fouled.
비만을 동반한 위암 환자에서 두 병을 같이 수술 치료한 경험(증례)
최경현,윤기영,문형환,신연명,서경원,안수미,송윤미,석정희,정경연,이은하 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3
Obesity is growing problem in Korea. We had a case of bariatric surgery during gastric cancer operation. Patient was 29 year old Korean lady with early gastric cancer located in the lesser curvature side of the middle 1/3 of the stomach. Her body weight was 89 kg, height 163 cm, and thus body mass index was 33.5 kg/m2. Preoperative blood pressure was 130/90 mmHg, hemoglobin 12.9 g/dL, total lymphocyte count 3,280/mL, serum albumin 4.3 g/dL, CEA 1.1 ng/mL, CA 19-9 9.1 ng/mL, and alpha fetoprotein 2 ng/mL. Another associated disease was right thyroid follicular neoplasm. The chest X-ray was normal. After IM injection of 2,500 units of heparin 30 minutes before the induction of general anesthesia, she received curative subtotal gastrectomy and Roux en Y gastrojejunostomy when a malabsorption loop of 120 cm jejunum was incorporated between the Treitz ligament and the end to side jejuno-jejunostmy site at May 29th 2006. Her postoperative course was uneventful except a minor wound seroma and the elevations of serum amylase(up to 4 folds) and lipase(up to 2 folds). She lost her body weight 9 kg in 5th, 21 kg in 7th, and 27 kg in 10th postoperative months to became 61.5 kg. On follow up exams in July 2008, she gained 4 kg to overcome her weakness and fatigue. From the above result, the incorporation of a malabsorption loop during reconstruction phase of gastric cancer operation was a good option for obese gastric cancer patients especially in cases of early gastric cancer.