단봉ㆍ회전운동이 오십견 질환자의 통증완화에 미치는 영향

최만준(Choi Man-Jun),김영민(Kim Young-Min) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.3

The purpose of this study was to verify the effects of combined exercise program by Kim’s G.C that a kind of vibration exercise equipment on pain relief in frozen shoulder patients. Exercise program was operated for 12 week, control group was participated in general resistance exercise program at a public health center and exercise group was additionally participated in combined exercise program by Kim’s G.C. General resistance exercise program was operated 3days per week and combined exercise program was operated for 30 minutes after general resistance exercise program. The main results of this study was as follows: First, the ROM of exercise group was more significantly increased than that of control group(p<.001). Second, there was significant increase in the ROM of exercise group after combined exercise program(p<.001). Third, the VAS of exercise group was more significantly decreased than that of control group(p<.001). Forth, there was significant decrease in the VAS of exercise group after combined exercise program(p<.001).

부산지역 무균성 뇌막염 원인 바이러스의 분리 및 동정 : 1998년을 중심으로

김영희,정영기,김기순,지영미,윤재득,김병준,구평태,민상기,정구영,김만수,조경순 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6, 25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing anti body test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.

간 세포암에서 VEGF, TGF-β1, b-FGF 발현의 의의

김성용,남충현,주종우,채만규,백무준,이문수,김형철,안현철,김홍수,김창진,김창호 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Purpose: Angiogenesis is important for the proliferation and the metastasis of solid tumors. The growth of a solid tumor is widely recognized to depend on the process of neovascularrozation. Without angiogenesis, tumors cease to grow beyond even a few milimeters in diameter. It has been shown that tumor vascular density is an independent prognostic marker in several types of human tumors and is known to correlate with poor prognosis. To date, many angiogenic factors have been identified, such as transforming growth factor-α(TGF-α), transforming growth factor-β(TGF-β), fibroblast growth factor family(FGF), vascular endothelial growth factor(VEGF), platelet derived endothelial cell growth factor(PD-ECGF), tumor necrosis factor-α(TNF-α), and angiogenin. Hepatocellular carcinoma(HCC) is the second most common tumor in Korean males and is known as a typical hypervascular tumor with frequent portal vein invastion. The authors identified the expreesion of VEGF, TGF-β1, and b-FGF in HCC specimens and evaluated the relationship between these growth factors and the clinicopathologic characteristics of HCC. Method: We reviewed the medical records of 30 patients who were diagnosed as hepatocellular carinoma treated with hepatic resection between January 1994 and December 1998 in Soonchunhyang University Chunan Hospital. The selection of the cases was decided according to the condition of paraffin block fixation. The prognostic factors such as age, sex, tumor size, concentration of serum α-fetoprotein, presence of liver cirrhosis, presence of tumor emboli in portal vein, TMN stage, amount of transfusion during the operation, hepatitis B virus(HBV) infection, and Edmonson-Steiner(E-S) grade were investigated. Relationship between the prognostic factors and the immunopathologic expression of the TGF-β1, b-FGF, and VEGF was examined. Result: Thirty patients (24 males, 6 females) were included in the current study. The patient's mean age was 50.6 years and the age ranged from 36 to 65 years. The mean size of the tumor was found to be 5.2cm. All the patients were follewed up for 7 to 63 months. Child's classification A patients were 23(76.7%)cases, B patients were 7(23.3%)cases, and C was none. Immunohistochemical staining of HCC tumor mass in VEGF expression patients were 17(56.7%), b-FGF expression patients were 10(33.3%), and TGF-β1 expression patients were 10(33.3%). VEGF expression or more than one positive expression among the three factors correlated with tumor size and the stage of HCC but did not correlated with other clinicopathological characteristics. TGF-β1 and b-FGF did not correlate with any clinicopathological characteristics. Conclusion: The results suggest that the expression of VEGF or more than one positive expression among the three factors in HCC cells may be a significant prognostic factor of HCC.

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

자궁경부에 발생한 배아성 횡문근육종 2예

박정열,조준식,김대연,이동헌,김종혁,김용만,김영탁,목정은,남주현 대한부인종양 콜포스코피학회 2002 Journal of Gynecologic Oncology Vol.13 No.3

횡문근육종은 소아와 청소년기에 가장 흔한 연부조직 육종이다. 발생 부위는 일반적으로 두부 및 경부, 그 다음으로 비뇨생식계이다 조직학적으로 배아성 횡문근육종, 국화상 육종, 폐포성 횡문근육종, 다형성 횡문근육종으로 나누어진다. 횡문근육종의 약 20%가 비뇨생식기에서 발생하고, 50% 이상이 배아성 횡문근육종이다. 여성 생식기의 배아성 횡문근육종은 드문 악성 종양으로,주로 유소아의 질에서 발생하며, 자궁경부에서 발생하는 횡문근육종은 청소년기에 흔하고, 질에서 기원하는 횡문근육종이 자궁경부에 기원하는 경우보다 5배 정도 많다. 폐경기여성에서는 자궁체부에서 가장 흔히 발생한다. 비뇨생식기의 횡문근육종의 치료는 과거에는 골반장기 적출술만으로 치료를 시도하였으나. 서서히 다중 항암화학요법, 방사선요법, 근치적 절제술을 포함한 병합요법으로 바뀌어가고 있으며, 이에 따라 생존율이 현저하게 향상되었다. 이에 저자들은 최근 본원 산부인과에서 자궁경부에 발생한 배아성 횡문근육종 2예를 경험하였기에 문헌 고찰과 아울러 보고하는 바이다. Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and young adult. Genitourinary tract is the econd most common site of rhabdomyosarcoma. Rhabdomyosarcoma can be classified into one of four major types; embryonal, alveolar, pleomorphic and undifferentiated. Embryonal rhabdomyosarcoma of the female genital tract is rare malignant tumor and usually occurs during childhood in the vagina. In rare cases, rhabdomyosarcoma can originate in the uterine cervix, with a peak incidence in the second decade. Recently we have experienced two cases of embryonal rhabdomyosarcoma of the uterine cervix. These cases are presented with a brief review of the literature.

급성 충수염으로 진단된 예측 불가 염증성 맹장 종물에 대한 외과적 고찰

민경진,백무준,채만규,김성용,이문수,김창호,김재준,송옥평 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Purpose: An unexpected inflammatory cecal mass of uncertain etiology was encountered during surgery for presumed appendicitis. In this case, the surgeon couldn't exclude differential diagnosis which were severe appendicitis involving the cecal region, diverticular disease, other inflammatory bowel diseases, and neoplasm. Therefore, this finding leads to a therapeutic dilemma for the surgeon, when making surgical decisions during the operation. The aim of this study was to resolve this dilemma, a retrospective review was undertaken in this study. Methods: A retrospective study was performed to review the management of this problem at Soonchunhyang University Chunan Hospital for eight and half years from July 1991 to December 1999. A review of the emergency operation records identified 50 patients who had undergone ileocecal resection or right hemicolectomy for an inflammatory ileocecal mass of uncertain etiology when operated on for probable appendicitis. Results: Altogether, 39 patients underwent ileocecal resection, and 11 patients underwent right hemicolectomy. The final pathologic diagnosis was appendiceal abscess in 32 patients (63%), cecal diverticulitis in 7 patients (14%), neoplasm in 6 patients (12%), appendiceal phlegmon in 3 patients (6%), ileal tuberculosis in 1 patient (2%) and Anisakiasis in another patient (2%). The neoplasm of the 6 neoplasm patients was ascending colon cancer for 4 patients and cecal cancer for 2 patients. There was no mortality in this group. Conclusion: Although most inflammatory cecal masses are caused by benign disease, all cases in which the intraoperative diagnosis is unclear, any pathologic diagnosis including neoplasm cannot be ruled out. So this suggest ileocecal resection or right hemicolectomy to remove a possible underlying malignancy, and to decrease morbidity and mortality.

노인에서 한국판 행동통제척도의 표준화 및 타당도 연구

김효진,이준영,정희연,나덕렬,조성진,조맹제,장성만 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.4

The aims of this study are to demonstrate the reliability and the validity of the Korean version of Behavioral Dyscontrol Scale (BDS-K.) and to present the normative values of BDS-K among the Korean elderly. The BDS-K was administered in a standardized manner to 1,389 healthy volunteers aged over 65 years recruited from the cornmunity. The elderly with serious neurological, medical or psychiatric disorders were excluded using screening tests. BDS-K showed good intemal consistency (Cronbach's alpha=0.812), test-retest reliability (r=0.88) and inter-rater reliability (r=0.99). Age and educational level were found to affect BDS-K score. Based on this result, normative values of BDS-K. were calculated by age and educational level. The validity of the BDS-K were demonstrated in comparison with MMSE-KC (r=0.72). BDS-K is reliable and valid instrument for measuring executive function of the elderly. The normative values suggested by this study can be widely used as reference values to objectively interpret BDS-K scores of the Korean elderly.

잡음환경에서 구름 볼 베이링의 결함검출을 위한 ALE의 적용

김영태,최만용,김기복,박해원,박정학,김종억,류준 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-

It is very important to detect the bearing defects in rotating machinery since the critical failure of bearing cause a machinery shutdown. However it is difficult to detect the vibration signal resulting from the initial defects of bearing because of the high level of broadband noise. A signal processing technique, called the adaptive line enhancer(ALE) as one of adaptive filter, is studied in this work. This technique is to eliminate broadband noise without a prior knowledge of the noise and signal characteristics. Also we propose the optimal methods for selecting the three main ALE parameters such as correlation length, filter order and adaptation constant used in the adaptative process. Vibration signals for three abnormal bearings, including inner and outer raceways and ball defects, were acquired from Anderon(angular derivative of radius on)meter. The experimental results showed that the proposed technique can reliably detect the bearing defective signals masked by broadband noise.

뇌지주막하 출혈 환자에게서 경두개도플러와 SPECT를 사용하여 측정한 이산화탄소 반응성에 대한 연구

김명현,신규만,송준혁 梨花女子大學校 醫科大學 醫科學硏究所 1998 EMJ (Ewha medical journal) Vol.21 No.1

The assessment of the cerebral vasoreactivity provides information regarding to the reserve capacity of the cerebral circulation in patients with cerebrovascular disease, which has important therapeutic consequencies because it allows for the diagnosis of impending ischemia and for the control of the effect of initiated correcitive measures. The author performed transcranial doppler study to measure the CO2 reactivity to the entire basal cerebral arteries in 30 cases of control group and 10 cases of disease group between 3rd and 7th day after insult. The control persons involved 10 cases of 3rd decade, 10 cases of 5th, 10 cases of 7th, and the diasease persons involved 10 cases of spotanenous subarachnoid hemorrhages. All disease patients were examined by single photon emission computed tomography and their results were compared to Doppler CO2 reactivities. In control group, the mean blood flow velocity and pulsatility index increased with age, but the CO2 reactivity decreased. In patient group, MBFV, PI index, MI ratio were not correlated to the presence of disease, but only CO2 index was decreased than the same age group of normal control. The regions showing abnormal ROI by SPECT well corresponded with the regions showing decreased CO2 reactivity. There was no close correlation between ROI(Region of Interest) index and CO2 index, but the CO2 reactivity was remarkably decreased in the region which showed abnormal regional cerebral blood flow in SPECT findings(p=0.04). In the relationship between the various prognostic factors, ROI increased as the clinical status worse(r=-0.05, p=0.0008), the acute prognosis(3Mo) had positive correlation with CO2 omdex(r=0.32, p=0.04) or clinical status, and negative correlation with ROI index(r=0.40, p=0.0094). Transcranial doppler CO2 testing in patients with spotanenous subarachnoid hemorrhage provides useful information regarding hemodynamic state, prognosis and determination of beneficial effects specific therapy. In the various TCD parameters, CO2 index was correlated well with the acute prognosis.

제품유형에 따른 스포츠보증인의 속성이 광고효과에 미치는 영향

김용만,이준원 한국방송광고공사 2006 광고연구 Vol.0 No.73

스포츠스타의 대중적 인기가 높아지면서 기업이 커뮤니케이션 수단으로 스포츠보증인을 활용되는 사례가 늘고 있다. 이 연구에서는 광고전략모델 중 FCB Grid 모델을 적용하여 제품유형별로 스포츠보증인의 속성이 제품유형에 따라 광고효과에 미치는 영향에 대한 차이가 있는지를 이론적 인과구조모형을 검증함으로서 규명하고자 하였다. 연구결과 전체적인 인과구조모형의 적합도는 적절한 것으로 나타났으며, 적합도 검증결과가 타당함에 따라 개별가설을 통해 개념간 관계를 확인하였는데, 그 결과를 보면 다음과 같다. 첫째, 스포츠보증인 속성 중 전문성을 제외하고 신뢰성, 애호성 그리고 유사성은 광고태도에 유의한 영향을 미쳤다. 둘째, 광고태도는 구매의도를 제외하고 브랜드태도, 브랜드동일시 그리고 브랜드이미지에 유의한 영향을 미쳤다. 셋째, 브랜드태도는 브랜드이미지와 구매의도에 유의한 영향을 미쳤다. 넷째, 브랜드동일시는 브랜드태도, 브랜드이미지 그리고 구매의도에 유의한 영향을 미치는 것으로 나타났다. 다섯째, 브랜드이미지는 구매의도에 유의한 영향을 미치는 것으로 나타났다. 그리고 제품유형별 각 변수간 영향력을 분석한 결과 경로구조가 다소 차이가 있음을 발견했다. 즉, FCB Grid 상‘고관여/감성’,‘ 고관여/이성’, ‘저관여/감성’그리고‘저관여/이성’모델간 스포츠보증인의 속성이 광고태도, 브랜드동일시, 브랜드태도 그리고 브랜드이미지를 매개로 구매의도에 미치는 영향력에 대한 광고효과구조가 다름을 확인할 수 있었다 The purpose of this study was to examine the casual relations of expertise, trustworthiness, likability, similarity, attitude toward advertising, attitude toward brand, brand identification, and brand image as well as purchasing intention. Data were analyzed through the Structural Equation Model (SEM), focusing on the theoretical structure. It was aimed at comparing and looking into the casual relations between celebrity athlete endorser and advertising effects of each type of products by applying FCB Grid Model among advertising strategic models through SEM Analysis. Data were collected using quota convenience sampling (N=779). The subjects of this study were college students. The goodness of fit was confirmed utilizing AMOS 4.0. Findings of this study were as follows; First, the trustworthiness, likability, and similarity of the celebrity athlete endorser had a significant influence on attitude toward advertising. but the expertise of the celebrity athlete endorser didn't have a significant influence on attitude toward advertising. Second, the attitude toward advertising had a significant influence on attitude toward brand, brand identification, and brand image. But attitude toward brand didn't have a significant influence on the purchasing intention. Third, attitude toward brand had a significant influence on the brand image and purchasing intention. Forth, the brand identification had a significant influence on attitude toward advertising, brand image, and purchase intention. Fifth, the brand image had a significant influence on the purchase intention. Lastly, the influences among variables by product types generated more or less differences, producing different structural models. This study provides insight into both the nature of athlete endorsement and how it might be used in future marketing research.