다운증후군의 산전진단을 위한 다양한 선별검사의 기여율 비교 - 산전 및 신생아때 진단된 96 례 분석 -

한정열(J . Y . Han),김문영(Y. M . Kim),조준형(J . H . Cho),안현경(H . K . Ahn),류현미(H . M . Ryu),김진미(J . M . Kim),김영미(Y . M . Kim),박소연(S . Y . Park),한혜경(H . K . Han),이영호(Y . H . Lee),양재혁(J . H . Yang) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10

연구의 목적은 다운증후군을 산전진단하기 위한 다양한 산전선별검사 (나이; 35세 이상, 임산부 혈청 marker를 이용한 triple test, 초음파; 비정상 소견, 후경부 투명대 (nuchal translucency), 후경부두께 (nuchal fold thickness))의 기여율를 비교하기 위한 것이다. 1990년 1월부터 1999년 9월까지 본원에서 산전 및 산후에 진단된 례는 총 96례 이었다. 산전 및 신생아기에 진단된 다운증후군의 빈도는 각각 68례 (71 %), 28례 (29 %)였다. 다운증후군 태아를 임신했던 임산부의 평균연령은 33±5.7세이다. 다운증후군의 1,000분만당 연도별 빈도율은 1990년부터 1999년까지 각각 0.4, 1.3, 0.7, 0.7, 1.6, 0.7, 1.2, 2.2, 2.0, 그리고 2.3 (Y=0.28±0.18 year, P=0.01)이었다. 산전진단된 다운증후군의 비율 (%)은 지난 10년간 각각 0 (0/2), 43 (3/7), 50 (2/4), 25 (1/4), 56 (5/9), 100 (5/5), 71 (5/7), 78 (14/18), 78 (14/18), 그리고 89 (17/19) (Y=12.9±8.9 year, P=0.000) 이었다. 다운증후군을 산전진단하기 위한 다양한 산전선별 검사에 따른 기여율은 35세이상의 연령에 의하면 30.2±5.6 %, triple test의 경우 18.2±3.4 %, 초음파에 의한 경우 51.7±6.3 % 이며, 초음파에 의한 산전 선별 검사가 통계적으로 유의하게 연령이나 triple test에 의한 경우 보다 다운증후군의 산전진단에 기여율이 높았다. (P=0.008) 결론적으로 본 연구에 의하면 지난 10년 동안 다운증후군을 산전 진단하기 위한 여러 선별 검사방법의 적용은 효율적이었으며, 특히 초음파에서 다양한 소견을 이용한 다운증후군의 산전선별검사는 연령이나 triple test 보다는 더욱더 의미가 있다고 추론된다. Objective : The purpose of this study was comparison of the contribution rate for prenatal diagnosis of Down syndrome using various screening methods (Age: greater than or equal to 35 years old, Serum markers: Triple test, Ultrasonography: abnormal sonographic findings, nuchal translucency, nuchal fold thickness).Methods : Total 96 cases of Down syndrome, prenatally or postnatally diagnosed between Jan. 1990 and Sept. 1999, made up the study population. We got the contribution rate of various prenatal screening methods of down syndrome, and obtained the efficiency of various screening program applied for last 10 years. Results : The frequencies of Down syndrome confirmed in prenatal and postnatal were 68 (71%) and 28 (29%) in respectively. The mean age of mother of Down syndrome fetus was 33.0±5.7 years old. The frequency rate of Down syndrome was 0.4, 1.3, 0.7, 0.7, 1.6, 0.7, 1.2, 2.2, 2.0 and 2.3 a 1,000 deliveries from 1990 to 1999 (Y= 0.28+0.18 year, P=0.01). The percentage of Down syndrome diagnosed prenatally was 0 (0/2), 43 (3/7), 50 (2/4), 25 (1/4), 56 (5/9), 100 (5/5), 71 (5/7), 78 (14/18), 78 (14/18) and 89 (17/19) from 1990 to 1999 (Y= 12.9+8.9 year, P=0.000). The contribution rate of prenatal diagnosis for Down syndrome was 30.2±5.6% by age, 18.2±3.4% by triple test and 51.7±6.3% by ultrasonography, and was significantly difference among each screen methods (P=0.008). Conclusions : This study shows that our prenatal screening program is highly effective to detect Down syndrome and especially ultrasonographic findings (abnormal sono findings, Nuchal translucency, Nuchal fold thickness) may be more important than that of age or Triple test to detect the Down syndrome prenatally.

Effects of $BaCO_3$ purity on the superconducting properties of top seeded melt growth processed $Y_{1+x}Ba_2Cu_3O_y$ superconductors

Choi, J.S.,Park, S.D.,Jun, B.H.,Han, Y.H.,Sung, T.H.,Choo, K.N.,Kim, C.J. The Korean Society of Superconductivity and Cryoge 2009 한국초전도저온공학회논문지 Vol.11 No.2

Effects of $BaCO_3$ purity on the superconducting properties of top seeded melt growth (TSMG) processed $Y_{1+x}Ba_2Cu_3O_{7-y}$ (Y1+x, x=0.1 and 0.2) superconductors were investigated. $YBa_2Cu_3O_{7-y}$ (Y123) powder prepared using $BaCO_3$ with 99.75% purity and commercially available Y123 powder of 99.9% were used for the fabrication of single Y123 grain superconductors. $T_c$ values of the Y1+x samples prepared using low purity Y123 powder were slightly lower than those of the samples prepared using a high purity powder. In addition to the lower $T_c$, an anomalous peak effect in the intermediate magnetic fields was observed in Y1+x samples prepared using the low purity $BaCO_3$ powder. The slight decrease in $T_c$ and the anomalous peak effect are ascribed to the possible incorporation of a Y123 phase with impurity elements such as strontium and calcium included in the $BaCO_3$powder of 99.7%. The result suggests that the low purity $BaCO_3$ powder of a low price can be used as a raw power for the fabrication of single grain YBCO bulk superconductors.

Particle distribution in melt-processed Y_1.5 Ba₂Cu₃O_x superconductors with BaCeO₃ addition

Youn, J.S.,No, K.,Kim, Y.H.,Mahmood, A.,Jun, B.H.,Han, Y.H.,Sung, T.H.,Kim, C.J. North-Holland 2009 Physica. C, Superconductivity Vol.469 No.15

To understand the effect of BaCeO<SUB>3</SUB> on a Y<SUB>2</SUB>BaCuO<SUB>5</SUB> (Y211) distribution, Y<SUB>1.5</SUB>Ba<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>x</SUB> (Y1.5) superconductors with/without 1wt.% BaCeO<SUB>3</SUB> additions were prepared by a top-seeded melt-textured growth (TSMG) process. Two different BaCeO<SUB>3</SUB> powders (as-synthesized (coarse powder) and an attrition-milled (fine powder)) were used and the size effect was compared with that obtained from a Y1.5 sample with no addition. A refinement of the Y211 particles was achieved for both the as-synthesized and attrition-milled BaCeO<SUB>3</SUB> additions. The distribution of the Y211 particles was most uniform in the Y1.5 sample prepared with the attrition-milled BaCeO<SUB>3</SUB> powder due to the reduced size of the Y211-free regions by the fine size BaCeO<SUB>3</SUB> addition. The highest J<SUB>c</SUB> was achieved in the Y1.5 sample prepared with the attrition-milled BaCeO<SUB>3</SUB> powder. The J<SUB>c</SUB> result agreed well with the microstructure variations by the addition of BaCeO<SUB>3</SUB> powders.

Effects of calcium doping on the superconducting properties of top-seeded melt growth processed Y_1.5Ba_2-xCa_xCu₃O_y superconductors

Park, S.D.,Kim, H.J.,Park, B.J.,Han, Y.H.,Jun, B.H.,Lee, J.S.,Kim, C.J. North-Holland 2011 Physica. C, Superconductivity Vol.471 No.21

The effect of calcium doping on the superconducting properties of top seeded melt growth (TSMG) processed Y<SUB>1.5</SUB>Ba<SUB>2-x</SUB>Ca<SUB>x</SUB>Cu<SUB>3</SUB>O<SUB>y</SUB> superconductors was studied in terms of calcium content (X<SUB>ca</SUB>). YBa<SUB>2-x</SUB>Ca<SUB>x</SUB>Cu<SUB>3</SUB>O<SUB>7-δ</SUB> (X<SUB>ca</SUB>=0, 0.005, 0.01, 0.02, 0.04, 0.1, 0.3) powders were synthesized by the powder calcination method. YBa<SUB>2-x</SUB>Ca<SUB>x</SUB>Cu<SUB>3</SUB>O<SUB>7-δ</SUB> powders were mixed with 0.25mole Y<SUB>2</SUB>O<SUB>3</SUB> powder and 1wt.% CeO<SUB>2</SUB> as Y<SUB>2</SUB>BaCuO<SUB>5</SUB> (Y211) refiner, and finally made into Y<SUB>1</SUB>.<SUB>5</SUB>Ba<SUB>2-x</SUB>Ca<SUB>x</SUB>Cu<SUB>3</SUB>O<SUB>y</SUB> (Y1.5)+1wt.% CeO<SUB>2</SUB> composition. The single Y123 growth on the top surface was observed up to X<SUB>ca</SUB>=0.1, while the multiple Y123 growth was observed at X<SUB>ca</SUB>≥0.1. The superconducting transition temperature (T<SUB>c</SUB>) and critical current density (J<SUB>c</SUB>) of TSMG processed Y1.5 samples were inversely proportional to X<SUB>ca</SUB>. The Y211 size increased with increasing X<SUB>ca</SUB> due to the enhancement of Y211 coarsening by calcium doping. No Y211 refining effect by CeO<SUB>2</SUB> was observed in the calcium doped samples. The T<SUB>c</SUB> and J<SUB>c</SUB> decrease by calcium doping are likely to be due to the calcium incorporation with the Y123 lattice and formation of coarse Y211 particles.

Effects of Y₂O₃ additions on the oxygen diffusion in top-seeded melt growth processed YBa₂Cu₃O_7-y superconductors

Jun, B.H.,Jung, S.A.,Park, S.D.,Park, B.J.,Han, Y.H.,Kim, C.J. North-Holland 2011 Physica. C, Superconductivity Vol.471 No.21

To understand the effect of Y<SUB>2</SUB>BaCuO<SUB>5</SUB> (Y211)/YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7-y</SUB> (Y123) interfaces on the oxygen diffusion in single grain YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7-y</SUB> superconductors, single grain Y123 superconductors with 0.05 and 0.3moles of Y<SUB>2</SUB>O<SUB>3</SUB> additions were fabricated by a top-seeded melt growth (TSMG) process. Y123 compacts with Y<SUB>2</SUB>O<SUB>3</SUB> additions were subjected to melt growth heating cycles with a cooling rate of 1<SUP>o</SUP>C/h through a peritectic temperature (1015<SUP>o</SUP>C) and then annealed at 450<SUP>o</SUP>C for 200h in flowing oxygen. The superconducting temperature (T<SUB>c</SUB>) and critical current density (J<SUB>c</SUB>) were estimated for the three different regions (top surface (s), intermediate (i) and center (c)) of samples. The amount of Y211/Y123 interface area in single grain Y123 superconductors was successfully controlled by Y<SUB>2</SUB>O<SUB>3</SUB> additions. The T<SUB>c</SUB> values of s regions were higher than those of i and c regions, which indicates the presence of more oxygen at the sample surfaces. In addition, the T<SUB>c</SUB> values of i and c regions of the Y123 sample with 0.3mole Y<SUB>2</SUB>O<SUB>3</SUB> addition were higher than those of the same regions of the Y123 sample with 0.05mole Y<SUB>2</SUB>O<SUB>3</SUB> addition due to the promoted oxygen diffusion through Y211/Y123 interfaces and other related defects. In spite of the promoted oxygen diffusion by Y<SUB>2</SUB>O<SUB>3</SUB> addition, the large T<SUB>c</SUB> difference among the regions still existed, which suggests sluggish oxygen diffusion into single Y123 grains.

상엽수확고(桑葉收穫高) 측정(測定)에 관(關)한 연구(硏究) -각형질(各形質) 가중치(加重値)(Weight)에 의(依)한 수량(收量)의 측정(測定)-

한경수 ( K. S. Han ),장권열 ( K. Y Chang ),안정준 ( J. J. Ahn ) 한국잠사학회 1969 한국잠사곤충학회지 Vol.9 No.-

상엽의 수확고를 측정하기 위하여 상엽의 수량과 높음 상관관계가 있는 형질 중 상전에서 쉽게 측정할 수 있는 기조장(X1), 기조직경(X2), 엽수(X3), 엽면적(X4)의 4개 형질을 측정하여 이들 형질의 수량에 영향하는 가중치를 다중회분방정식에 의하여 산출하여 수량을 측정할 수 있도록 여러 가지 식을 유도하였다. 1. 기조장(X1)과 기조직경(X2)을 측정하여 수량을 측정하기 위하여는 개량서반에 있어서는 y1v1=-1.15760+0.068X1+165.756X2(g) 일지뢰에 있어서는 y1v2=-221.500+1.768X1+38.152X2(g) 노상에 있어서는 y1v2=-253.826-0.116X1+289.507X(g) 수원상 4호에 있어서는 y1v4=-157.559+1.063X1+106.088X2(g)의 식에 의해서 기조장(X1)과 기조직경(X2)의 측정치를 대입하면 수량을 견적할 수 있다. 2. 기조장(X1), 기조직경(X2), 엽수(X3)의 3개 형질을 측정하여 수량을 견적하는 데는 각품종별로 각각 y2v1=-118.478-0.665X1+184.445X2+2.346X3 y2v2=217.432+2.062X3+35.668X2-1.058X3 y2v3=-206.249-0.739X1+268.08X2+2.770X3 y2v4=-153.383+0.009X1+2.024X2+0.171X3의 식에 의하여 수량을 견적할 수 있다. 3. 기조장(X1), 기조직경(X2), 엽수(X3), 엽면적(X4)의 4개 형질을 측정하고 수량을 견적하기 위하여는 각품종별로 각각 y11v1=82.567-1.283X1+15.501X2+0.640X3+3.511X4 y11v2=136.411+0.311X1+1.921X2-0.217X3+0.214X4 y11v3=150.2Z7-0.139X1+11.788X2+0.143X3+0.381X4 y11v4=160.850+0.323X1+66.076X2-0.794X3+2.614X4 등의 식에 의하여 수량을 견적할 수 있다. Various formulae for estimation of leaf production in mulberry trees were investigated and obtained. Four varieties of mulberry trees were used as the materials, and four characters, namely branch length (X, 1), branch diameter (X, 2), leaf number per branch (X, 3), and leaf area per branch (X, 4), were studies. The formulae to eatimate the leaf yield of mulberry trees are as follows: 1. Y1v1=-115.760+0.068X1+165.756X2 Y1v2=-221.500+1.768X1+38.152X2 Y1v8=-253.826-0.116X1+289.507X2 Y1v4=-157.559+1.063X1+106.088X2 where Y1v1, Y1v2, Y1v3, Y1v4, are showed the estimated yield of the each variety, namely Gaeryang souban, Ilchirye, Nosang, and Suwon Sang No. 4, respectively. X2 and X2 denote the measured values of branch length and branch diameter, respectively. 2. Y2v1=-118.478-0.665X1+184.445X2+2.346X3 Y2v2=-217.432+2.062X1+35.668X2-1.058X3 Y2v3=-206.249-0.739X1+268.08X2+2.770X3 Y2v4=-153.383+0.009X1+2.024X2+0.171X3 where Y2v1, Y2v2, Y2v3, Y7v4, are the estimated yield of the each variety, namely Gaeryang. Souban, Ilchirye, Nosang, and Suwon Sang No. 4, respectively. X1, X2, X3, denote the measured values of each character, branch length, branch diameter and leaf number per branch, respectively. 3. Y11v1=82.567-1.283X1+15.501X2+0.640X3+3.511X4 Y11v2=136.411+0.311X1+1.921X2-0.217X3+0.214X4 Y113v=150.227-0.139X1+11.788X2+0.143X3+0.381X4 Y11v4=-160.850+0.323X1+66.076X2-0.794X3+2.614X4 where Y11v1, Y11v2, Y11v3, Y11v4, are the estimated yield values of four varieties, and X1, X2, X3, X4 denote the measured values of four characters, namely branch length, branch diameter, leaf number per branch and leaf area per branch, respectively. The estimation method of mulberry leaf yield by measurement of some characters, branch length, branch diameter, leaf number per branch and leaf area per branch, could be the better method to determine the leaf yield of mulberry trees without destroying the leaves and without weighting the leaves of mulberry trees than the other methods.

Effective pore control and critical current density in liquid infiltration growth processed Y-123 superconductors with Ag addition

Mahmood, A,Jun, B-H,Han, Y H,Kim, C-J IOP Publishing Ltd 2010 Superconductor science & technology Vol.23 No.6

<P>The effect of a sintered density (open porosity) of Y<SUB>2</SUB>BaCuO<SUB>5</SUB> (Y211) pre-forms on the final porosity and Y211 size within Y Ba<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7 − <I>y</I></SUB> (Y-123) products was systematically studied in liquid infiltration growth (LIG) processed Y-123 bulk superconductors with Ag addition. To prepare Y211 pre-forms of various densities, Y211 powder compacts were sintered in air at various temperatures of 900–1200 °C. The single-grain Y-123 bulk superconductors were fabricated by the LIG process with top seeding. It was found that the porosity of the final Y-123 product was fairly dependent on the Y211 pre-form density. When a Y211 pellet of a high density was used as a pre-form for the LIG process, the porosity of the final Y-123 product was greatly reduced. In addition to the reduced porosity, the enhanced Y211 refinement was achieved for the Y-123 product prepared using the dense Y211 pre-form, resulting in the improved critical current density (<I>J</I><SUB>c</SUB>). The Ag addition was also helpful in eliminating the spherical pores through pore filling with a silver melt. The pore elimination and Y211 refinement mechanism in the LIG-processed Y-123 bulks were explained in terms of the liquid capillary movement and Ag melt and particle coarsening at the (Y 211 + melt) state.</P>

2001년 11월 오염시기와 2002년 봄 황사시기 제주도 고산에서의 미량원소 농도 변화

한진석,김영성,문광주,안준영,김정은,류성윤,김영준,공부주,이석조 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.2

The chemical composition of PM_(2.5) was measured at Gosan. Jeju for two weeks each in November 2001 and spring 2002. In the latter part of the measurement period of November 2001, designated as the polluted period in this work, secondarily formed ion components as well as primarily emitted elemental carbon were high, PM_(2.5) mass concentration was also high in this polluted period compared with the yellow sand period, in which daily average of PM_(10) peaked up to 520㎍/㎥. Increase of major components of anthropogenic origin in the polluted period was not correlated with the variation in sea salt components while increase of crustal components in the yellow sand period was highly correlated with the variation in sea salt components. Trace elements were generally higher in the yellow sand period: however, toxic heavy metals such as zinc, cadmium and lead were the highest in the polluted period.

Co-Y 비정질 박막합금의 자기적 성질

강일구,김희중,한석희,이정중,김광윤 대한금속재료학회(대한금속학회) 1990 대한금속·재료학회지 Vol.28 No.11

The magnetic properties of amorphous Co-Y thin films prepared by RF magnetron sputtering have been investigated. The saturation magnetization of Co-Y alloy is linearly decreased with increasing Y content, and the magnetic moments of Co-Y alloys larger than those of Friedel's theory were interpreted by the atomic size effect. The coercive force is drastically decreased at about 8 at.% Y which is the minimum solute concentration to get the amorphous phase. The solute concentration of film is monotonously increased with increasing Ar pressure, and the coercive force shows the lowest values at the Ar pressure of 5 mTorr. Effective permeability in hard direction of thin film produced in magnetic field is lower at low Frequencies but higher at high frequencies above 100 ㎑ than those of easy direction. The rotating magnetic field annealing is effective to increase the effective permeability at overall frequency range.

대학생의 암 예방 수칙에 대한 인식 및 실천행태 연구

곽지연,김서연,김자영,이혜연,정문정,진수현,천선우,하소현,한희진,양숙자,김지연 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: The purpose of this study was to identify college student's perception and practice of 'National Cancer Prevention Actions' and the factors that influence the perception and practice. Method: The participants were 310 undergraduates selected by convenience sampling at colleges in Seoul. Instrument was 2014 Survey of Perception and Practice of National Cancer Prevention Actions by National Cancer Center(2014), and has been modified for the purpose of the study. The data were analyzed by t-test, ANOVA and Scheffe test with SPSS 23.0 Windows software. Results: The most recognized action for cancer prevention in college students was "Do not smoke, also avoid smoking smoke"(96.8%) while the most unrecognized was "Get a type B hepatitis vaccination"(58.7%). The most practiced action for cancer prevention in college students was "Sexually as to safe sex"(94.8%) while the most unpracticed was "Exercise five times a week or more, for at least 30 minutes a day"(33.9%). Among general characteristics, participants' age (t=-2.015, p<.05), major (F=3.109, p<.001), and residential type (F=4.959, p<.01) were statistically significant in the recognition of Cancer Prevention Actions and major(F=3.341 p<.05) and residential type(F=3.827, p<.05) were also significant in the practice of Cancer Prevention Actions. Among health characteristics, health concern(F=3.154, p<.05) and education in cancer(t=-3.112, p<.01) showed statistically significant differences in the recognition of Cancer Prevention Actions while health concern(F=7.896 p<.001) and subjective health status(F=9.913, p<.001) showed differences in the practice of Cancer Prevention Actions. Conclusion: These findings showed the gap between the perception and practice of cancer prevention actions. Considering the importance of individual characteristics, it is essential to develop a differentiated cancer prevention education program for college students. Also, nursing intervention program should be developed to raise the alertness of cancer in order to enhance cancer preventive practice.