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Seol, Hyun-Joo,Oh, Min-Jeong,Yeo, Min-Koo,Kim, Aeree,Lee, Eung-Seok,Kim, Hai-Joong Marcel Dekker, Inc 2010 Hypertension in pregnancy Vol.29 No.3
<P>Objective. The aim of this study was to evaluate serum resistin levels in women with preeclampsia compared to those in normal pregnant women and normal non-pregnant women, and to examine placental resistin expression. Methods. Serum resistin levels were measured by enzyme-linked immunosorbent assay and placental resistin expression was determined by immunohistochemistry. Results. Serum resistin levels were significantly elevated in women with preeclampsia compared to normal pregnant women and non-pregnant women. There was no significant difference in placental resistin expression. Conclusion. The placenta may not be the origin of the resistin that contributes to increased serum levels in women with preeclampsia.</P>
Status and prospect of workforce requirement for surgery in republic of Korea
Joo Hyun Kim,Sang Seol Jung,In Kyu Lee,Byung Joo Song,Jae Hwan Moon,Yong-Seog Jang,Hyuk-Joon Lee,Eun Sook Lee,Wang Jun Lee,Kil Yeon Lee 대한외과학회 2011 Annals of Surgical Treatment and Research(ASRT) Vol.81 No.6
Purpose: In order to prepare long-term alternatives to surgical residency training and workforce policies in Korea, objective data are needed; in addition, determination of the status of surgical procedures being performed is also needed. Methods: Cases of surgeries performed by board-certified Korean surgeons for 1 year, from July 2009 to June 2010 were reviewed and analyzed. Variation of the last five years was also investigated against the number of surgery cases of the same item and for data on status of population, medical institutions, and surgeons. Results: Difficulty in distribution of a given surgery varied according to the classification of medical institution types, and performance of highly difficult surgeries occurred more in tertiary hospitals. The number of surgeries has increased over the last 5 years (28.1%). The number of surgeries among elderly patients (41.5%), high difficulty (41.8%), and tertiary hospitals (34.9%) has especially increased. There has been no increase in the number of diagnosis related group claim cases for the last 5 years (-0.8%). 43.3% of surgeons working at private clinics in Korea did not present surgery as an indicating item of their clinics. Conclusion: While the demand for surgeons in high risk and highly difficult surgeries is continuously increasing, stagnation is expected in the traditional area. Considering the proportion and current status of surgeons working at private clinics, the need for a realistic reduction in the quota of surgical residents and reconsideration of personnel policies is raised.
( Hyun Soo Park ),( Won Joon Seong ),( Joon Seok Hong ),( Hyun Joo Seol ),( Han Sung Hwang ),( Kunwoo Kim ),( Hyun Sun Ko ),( Dong Wook Kwak ),( Soo Young Oh ),( Moon Young Kim ),( Sa Jin Kim ) 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.6
Objective To analyze practice patterns and checklists of second trimester ultrasonography, and to investigate management plans when soft markers are detected among Korean Society of Ultrasound in Obstetrics and Gynecology (KSUOG) members. Methods An internet-based self-administered questionnaire survey was designed. KSUOG members were invited to the survey. Checklists of the second trimester ultrasonography were also requested. In the questionnaire survey, general practice patterns of the second trimester ultrasonography and management schemes of soft markers were asked. In the checklists analysis, the number of items were counted and also compared with those recommended by other medical societies. Results A total of 101 members responded. Eighty-seven percent routinely recommended second trimester fetal anatomic surveillance. Most (91.1%) performed it between 20+0 and 23+6 weeks of gestation. Written informed consents were given by 15.8% of respondents. Nearly 60% recommended genetic counseling when multiple soft markers and/or advanced maternal age were found. Similar tendencies were found in the managements of individual soft markers. However, practice patterns were very diverse and sometimes conflicting. Forty-eight checklists were analyzed in context with the number and content of the items. The median item number was 46.5 (range, 17 to 109). Of 49 items of checklists recommended by International Society of Ultrasound in Obstetrics and Gynecology and/or American Congress of Obstetricians and Gynecologists, 14 items (28.6%) were found in less than 50% of the checklists analyzed in this study. Conclusion Although general practice patterns were similar among KSUOG members, some of which were conflicting, and there is a need for standardization of the practice patterns and checklists of second trimester ultrasonography, which also have very wide range of spectrum.
( Hyun-joo Seol ),( Ji-hee Sung ),( Won Joon Seong ),( Hyun Mi Kim ),( Hyun Soo Park ),( Hayan Kwon ),( Han-sung Hwang ),( Yun Ji Jung ),( Ja-young Kwon ),( Soo-young Oh ) 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.1
Objective To provide a standardized protocol for the measurement of cervical strain elastography, present its reproducibility, and analyze baseline clinical factors affecting the measurement of elastographic parameters. Methods This study was performed by the Korean Research Group of Cervical Elastography. We enrolled pregnant women according to our study protocol. After measuring the cervical length, elastography was performed using the E-Cervix™ quantification tool to measure the strain of the cervix using intrinsic compression. We evaluated 5 elastographic parameters, namely, the strain of the internal os of the cervix (IOS), strain of the external os of the cervix (EOS), ratio of the strain of IOS and EOS, elasticity contrast index, and hardness ratio. For baseline clinical factors, we examined the maternal body mass index, blood pressure, heart rate, uterine artery Doppler indices, and fetal presentation. Results We established a specific protocol for the measurement of cervical elastography using the E cervix program. For all elastographic parameters, the intra-observer intraclass correlation coefficient (ICC) ranged from 0.633 to 0.723 for single measures and from 0.838 to 0.887 for average measures, and the inter-observer ICC ranged from 0.814 to 0.977 for single measures and from 0.901 to 0.988 for average measures. Regression analysis showed that the measurement of the elastographic parameter was not affected by baseline clinical factors. Conclusion We present a standardized protocol for the measurement of cervical elastography using intrinsic compression. According to this protocol, reproducibility was acceptable and the measurement of elastographic parameters was not affected by the baseline clinical factors studied.
Progesterone Treatment for Prevention of Preterm Birth
( Hyun-joo Seol ),( Suk Joo Choi ),( Soo-young Oh ) 대한주산의학회 2016 Perinatology Vol.27 No.4
Preterm birth is the main cause of neonatal mortality and morbidity worldwide. Although many attempts and clinical trials have conducted to prevent preterm birth during the past decades, no convincing strategy was developed so far. In this background, there is no doubt that the research area under the spotlight in recent ten years was about progesterone treatment in women at high risk for preterm birth including prior preterm birth and short cervical length. This rigorous review aimed to provide the most updated knowledge on progesterone treatment for the prevention of preterm birth for physicians and included the history and the proposed mechanism of progesterone treatment, summary of clinical trials of progesterone treatment in singleton and twin gestation with prior spontaneous preterm birth and short cervical length, respectively. It also adduces long term outcomes in infants whose mother exposed to progesterone treatment during pregnancy and presents current evidence on comparison between intramuscular versus vaginal progesterone for the prevention of recurrent preterm birth.
이현주 ( Hyun Joo Lee ),정록선 ( Rok Seon Choung ),박민선 ( Min Seon Park ),표정희 ( Jeung Hui Pyo ),김승영 ( Seung Young Kim ),현종진 ( Jong Jin Hyun ),정성우 ( Sung Woo Jung ),구자설 ( Ja Seol Koo ),이상우 ( Sang Woo Lee ),최재 대한소화기학회 2014 대한소화기학회지 Vol.63 No.2
We presented two interesting cases of gastrocolocutaneous fistula that occurred after percutaneous endoscopic gastrostomy (PEG) tube placement, and its management. This fistula is a rare complication that occurs after PEG insertion, which is an epithelial connection between mucosa of the stomach, colon, and skin. The management of the fistula is controversial, ranging from conservative to surgical intervention. Endoscopists should be aware of the possibility of gastrocolocutaneous fistula after PEG insertion, and should evaluate the risk factors that may contribute to the development of gastrocolocutaneous fistula before the procedure. We reviewed complications of gastrostomy tube insertion, symptoms of gastrocolocutaneous fistula, and its risk factors. (Korean J Gastroenterol 2014;63:120-124)
정상 임신 기간 중 혈중 혈관내피 성장인자의 변화 및 혈소판 수와의 상관관계
설현주 ( Hyun Joo Seol ),이경욱 ( Kyong Wook Yi ),민주영 ( Joo Young Min ),오민정 ( Min Jeong Oh ),김해중 ( Hai Joong Kim ),이재관 ( Jae Kwan Lee ),허준용 ( Jun Yong Hur ),서호석 ( Ho Suk Saw ),박용균 ( Yong Kyun Park ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.9
목적 : 전자간증의 병리기전에 관영하는 것으로 알려진 혈관내피 성장인자 (vascular endothelial growth factor, 이하 VEGF로 약함)의 정상 임신기간동안의 혈중 변화양상을 규명하고 혈중 VEGF농도와 혈소판 수와의 상관관계를 알아보고자 하였다. 연구 방법 : 2002년 4월부터 2002년 7월까지 고려대학교 구로병원 산부인과에 내원한 33명의 정상 임산부를 대상으로 임신 초기 검사 시기 (7-8주), 모체혈청삼중표지물질 검사 Objective : The aim of the present study was to evaluate changes of vascular endothelial growth factor levels in maternal circulating blood during normal pregnancies and examine their relationship with maternal platelet counts. Methods : The 33 subjects w