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한주영,이성욱,나정열,김성일 한국음향학회 2004 韓國音響學會誌 Vol.23 No.1
천해환경에서 저주파 광대역신호와 수직선배열을 이용하여, 퇴적층의 지음향인자(층두께, 종파속도, 종파감쇠계수, 밀도)를 역추정하였다. 역산방법은 모델 기반의 역산으로 유전알고리즘 (Genetic Algorithm)을 이용한 일관적 광대역 정합장처리(Coherent Broadband Matched Field Processing)기법을 사용하였다. 저주파 광대역음원으로 사용된 상업용 전구의 내폭신 호는 짧은 시간동안 많은 변화를 포함하는 천이신호이기 때문에, 분석시 시간과 주파수에 따른 창함수의 조절이 요구되는데, 주기신호분석에 주로 사용되는 퓨리에 기반의 분석방법은 이러한 점에서 많은 어려움이 있다. 본 논문에서는 해양도파관에서 근거리 음파전달 시 계측된 시계열신호로부터 다중경로성분을 구분하고 추출하기 위하여 시간-주파수영역에서 창함수의 크기조절이 가능한 웨이블릿 변환을 통한 신호 분석을 수행하였고, 분석된 실측음장과 계산된 복제음장의 연속웨이블릿 계수를 상호상관 시킴으로써 비용함수를 정의하였다. 비용함수의 전역최고점을 찾는 최적화 과정을 통하여 각 퇴적층의 지음향인자들을 역추정하였다. 특히 역산인자의 민감도에 따른 퇴적층별, 인자별, 분리연산을 수행함으로써 최적화과정에서 참값으로의 수렴효율을 높였다. 역산의 결과 실험해역 퇴적물 상층부에는 두께 44.43m, 음속 1549 m/s의 모래-실트-점토질(sand-silt-clay)층이 존재하고, 그 하부에는 12.28m 음속 1993 m/s의 거친모래질(Coarse sand)층의 존재를 추정해 내었다. 또한 역산 결과를 시추자료 및 탄성파 자료와 비교함으로써 본 논문에서 제안한 역산 방법의 유효성을 확인하였다. An inversion method is presented for the determination of the compressional wave speed, compressional wave attenuation, thickness of the sediment layer and density as a function of depth for a horizontally stratified ocean bottom. An experiment for estimating those properties was conducted in the shallow water of South Sea in Korea. In the experiment, a light bulb implosion and the propagating sound were measured using a VLA (vertical line array). As a method for estimating the geoacoustic properties, a coherent broadband matched field processing combined with Genetic Algorithm was employed. When a time-dependent signal is very short, the Fourier transform results are not accurate, since the frequency components are not locatable in time and the windowed Fourier transform is limited by the length of the window. However, it is possible to do this using the wavelet transform a transform that yields a time-frequency representation of a signal. In this study, this transform is used to identify and extract the acoustic components from multipath time series. The inversion is formulated as an optimization problem which maximizes the cost function defined as a normalized correlation between the measured and modeled signals in the wavelet transform coefficient vector. The experiments and procedures for deploying the light bulbs and the coherent broadband inversion method are described, and the estimated geoacoustic profile in the vicinity of the VLA site is presented.
A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
한주영,홍성빈,이정진,김경은,여진엽,김소헌,남문석,김용성 대한골대사학회 2012 대한골대사학회지 Vol.19 No.2
Cushing's syndrome is characterized by central obesity, fatigability, weakness, amenorrhea, hirsutism, edema,hypertension, impaired glucose tolerance, and osteoporosis due to excessive production of steroids. Cushing's syndrome is an important cause of secondary osteoporosis. Patients with Cushing's syndrome have a high incidence of osteoporotic fractures. At least, 30-50% of patients with Cushing's syndrome experience fractures, particularly in the vertebral body. And it is consistent with the 50% prevalence of osteoporosis in patients with Cushing's syndrome. However,reports of multiple pathological fractures in young patients with Cushing's syndrome are rare. Thus, we describe the case of a 26-year-old woman with Cushing's syndrome accompanied with recurrent multiple osteoporotic fractures and being treated by parathyroid hormone. Careful consideration for the possibility of Cushing's syndrome will be necessary in case of young patients with a spontaneous multiple compression fractures in spine.
염산테트라싸이클린의 적용시간에 따른 특수 가공된 임프란트 표면 변화
한주영,박준봉,권영혁,허익,정종혁,Han, Ju-Young,Park, Joon-Bong,Kwon, Young-Hyuk,Herr, Yeek,Chung, Jong-Hyuk 대한치주과학회 2006 Journal of Periodontal & Implant Science Vol.36 No.3
The present study was performed to evaluate the effect of tetracycline-HCl on the change of implant surface microstructure according to application time. Implant with pure titanium machined surface, HA-coated surface and dual acid etched surface were utilized. Implant surface was rubbed with $50mg/m{\ell}$ tetracycline-HCL solution for ${\frac{1}{2}}$min., 1min., $1{\frac{1}{2}}$min., 2min., and $2{\frac{1}{2}}$min. respectively in the test group. Then, specimens were processed for scanning electron microscopic observation. The results of this study were as follows. 1. Both test and control group showed a few shallow grooves and ridges in pure titanium machined surface implants. There were not significant differences between two groups. 2. In HA-coated surfaces, round particles were deposited irregularly. The roughness of surfaces conditioned with tetracycline-HCL was lessened and the cracks were increased relative to the application time. 3. The etched surfaces showed the honey comb structures. The surface conditioning with tetracycline-HCI didn't influence on its micro-morphology. In conclusion, the detoxification with $50mg/m{\ell}$ tetracycline-HCI must be applied respectively with different time according to various implant surfaces.
아나필락시스쇼크로 오인된 기능성 부신경절종 -증례 보고-
한주영,이오현,김경은,한승백,김소헌,남문석,김용성,홍성빈 대한중환자의학회 2013 Acute and Critical Care Vol.28 No.2
Paraganglioma is a tumor originating from the extra-adrenal chromaffin cells, and functional paraganglioma causes paroxysmal hypertension, headache and tachycardia, due to excess excretion of catecholamine. However, rarely, ARDS, acute myocardial infarction, heart failure, arrhythmia, and pulmonary edema are also seen in patients with paraganglioma and clinical manifestations are depending on the patient’s intravascular volume status. Seventy one-years-old male was presented with hypotension and pulmonary edema after intravenous midazolam injection during colonoscopy under conscious sedation. The patient was initially suspected with anaphylactic shock, due to midazolam injection. However, later, he was diagnosed with paraganglioma, and blood pressure was successfully controlled with alpha adrenergic blockade. We suggest that when we encounter heart failure, pulmonary edema and shock of unknown origin, pheochromocytoma must be taken into consideration.
Serum Chemerin Levels Are Associated with Abdominal Visceral Fat in Type 2 Diabetes
한주영,김소헌,서영주,임현애,신희경,조순구,김채원,이승윤,이대형,홍성빈,김용성,남문석 대한의학회 2016 Journal of Korean medical science Vol.31 No.6
Chemerin is a recently identified adipokine suggested to play a role in obesity and its metabolic complications. The relationship between visceral obesity and serum chemerin levels in type 2 diabetes (T2DM) is unknown and may differ from that of subjects without diabetes. Therefore, we evaluated whether serum chemerin was associated with visceral abdominal obesity in patients with T2DM. A total of 218 Korean patients with T2DM were enrolled and metabolic parameters, abdominal visceral and subcutaneous fat areas, and serum chemerin levels were measured. Serum chemerin level showed positive correlation with fasting insulin, HOMA-IR, serum triglyceride, serum creatinine, urine albumin/ creatinine ratio, high-sensitivity C-reactive protein (hsCRP), fibrinogen, abdominal visceral fat area, visceral to subcutaneous fat area ratio, and negatively correlation with high density lipoprotein cholesterol and creatinine clearance (CCr) after adjusting for age, gender and body mass index. Multiple linear stepwise regression analysis showed that abdominal visceral fat area (β = 0.001, P < 0.001), serum triglyceride (β = 0.001, P < 0.001), CCr (β = -0.003, P = 0.001), hsCRP (β = 0.157, P = 0.001), fibrinogen (β = 0.001, P < 0.001), and BMI (β = 0.02, P = 0.008) independently affected log transformed serum chemerin levels. Higher serum chemerin level was associated with higher level of abdominal visceral fat area, serum triglyceride, hsCRP and fibrinogen and lower level of CCr in patients with T2DM. Serum chemerin may be used as a biomarker of visceral adiposity and chemerin may play a role in inflammation, decreased renal function, and increased cardiovascular risk in T2DM.
한주영,이형욱,이봉기,Hahn, Joo-Young,Lee, Hyeong-Uk,Lee, Bong-Ki 한국군사과학기술학회 2007 한국군사과학기술학회지 Vol.10 No.3
A range-frequency interference pattern is analyzed in the course of the propagation of ship noise in shallow water. It has been shown to exhibit striated bands of intensity maxima and minima in the spectrogram. The slope of the striations is an invariant of the modal interference and is described by a waveguide invariant parameter $\beta$. It turns out that this interference pattern is useful for identifying the physical properties of the waveguide such as seabed properties. In this article, the interference pattern is analyzed using image processing techniques to produce the distribution of the beta and the effects of sediment types and geoacoustic parameters on beta distribution are examined and characterized by moments of the distributions.