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한동욱 신라대학교 자연과학연구소 2012 自然科學論文集 Vol.22 No.-
Objectives : This study researched the effect of tongue position on the muscle activation by analyzing uscle activation of muscle surrounding the cervical spine. Materials & Methods : The 20 subjects of this experiment were university students in age 20s, who had no cervical deformities or muscle problems. We selected three kinds of muscles; the upper trapezius, splenius capitis and sternoclaidomattoid, and measured the muscle activation of the muscles around cervical spine. Tongue positions were seven; neutral, anterior protrusion, posterior retrusion, superior and inferior protrusion, left and right side protrusion. Measurement device was surface EMG(LXM-3204, Korea). The value of RMS(root mean square) was used for analysis of muscle activation. Results : Even if the muscle activations of all muscles increased according to tongue positions, only the muscle activation of upper trapezius increased significantly by posterior retrusion of tongue. Others didn't show the change of muscle activation significantly. Conclusion : In view of these results, However, we knew that we have to study more to find the possibility of change of muscle activation according to tongue position because of increase tendency of muscle activation.
한동욱 대한물리의학회 2022 대한물리의학회지 Vol.17 No.3
PURPOSE: By virtue of its location, the iliopsoas muscle has the potential to affect the function of the diaphragm. Therefore, the purpose of this study was to investigate the effects of passive stretching of the iliopsoas muscles on pulmonary function. METHODS: Twenty male university students participated in this study. Subjects with low back pain, negative results on the modified Thomas test, and chest breathing patterns not directly related to the function of the iliopsoas muscles were excluded from this study. A digital pulmonary function measuring device (Pony FX, COSMED Inc, Italy) was used to test pulmonary function. The test was performed three times: the first test before passive stretching, the second test 10 minutes after the first test, and the third after passive stretching. Passive stretching was performed 5 times for each of the left and right iliopsoas muscles. Passive stretching was carried out for 20 seconds followed by a 10-second break. The SPSSWIN (ver. 27.0) statistics program was used for data analysis, and the significance level was α =.05. RESULTS: Among slow vital capacity (SVC) parameters, tidal volume (VT), inspiratory reserve volume (IRV), inspiratory capacity (IC) and vital capacity (VC) improved significantly after passive stretching. Also, among the maximal effort vital capacity (MEVC) parameters, forced vital capacity(FVC) and forced expiratory volume in one second(FEV1) improved significantly after passive stretching. CONCLUSION: The results showed that among the various pulmonary function parameters measured, passive stretching of the iliopsoas muscles can improve the SVC and MEVC. Therefore, passive stretching of the iliopsoas muscles may be considered for use as a treatment method to improve pulmonary function.
한동욱,박민희,정연희,Han, Dong-Wook,Park, Min-Hee,Jeong, Yeon-Hee 한국임상보건과학회 2013 한국임상보건과학회지 Vol.1 No.1
Purpose : This study was to investigate that tongue positions have effect on the cervical range of motion (ROM). Methods : 18 subjects, 20 to 25 years of age, were participated in this study. The tongue positions were neutral position, anterior protrusion, posterior protrusion, superior protrusion, inferior protrusion, left side protrusion and right side protrusion. The neck movements were right side flexion, left side flexion, right rotation and left rotation. The cervical range of motion measured by cervical range of motion instrument (CROM, C9266-49, USA). The changes were analyzed using the paired t-test. SPSSWIN (ver. 20.0) was used for data analysis and the significance level was chosen as ${\alpha}$=0.05. Results : In the lateral flexion, the angle of left lateral flexion increased in anterior protrusion(p<0.05) and right side protrusion(p<0.05) significantly. In the rotation, the angle of right rotation increased in anterior protrusion(p<0.05), posterior protrusion (p<0.05), superior protrusion(p<0.05), inferior protrusion(p<0.05), and left side protrusion (p<0.05) significantly. Conclusions : In conclusion, we found that the tongue positions affected some cervical movements.
한동욱,박종철,임혜련,조한희,Kazuaki Matsumura,백현숙,이미희,우연이,현성휴 한국생체재료학회 2006 생체재료학회지 Vol.10 No.1
The migration of vascular smooth muscle cells (VSMCs) from the tunica media to the subendothelial region is a key event in the development and progression of atherosclerosis and post-angioplasty vascular remodeling. The abnormal growth of VSMC also plays an important role in vascular diseases, including arteriosclerosis and restenosis after angioplasty. Many in vitro assays have shown that ()-epigallocatechin-3-O-gallate (EGCG) has antiproliferative effects on various cells. In this study, the proliferation of rat aortic SMCs (RASMCs) with serum stimulation were investigated into EGCG-loaded collagen matrices (EGCG-CM). Also, the effect of EGCG-CM was examined on the migration of serum-stimulated RASMCs. RASMCs were primarily cultured from rat aorta and then characterized by using immunocytochemical analysis with -smooth muscle actin antibody. EGCG treatment to RASMCs showed a dose-dependent decrease in cell viability as increase in its concentration. EGCG-CM was fabricated by freeze-drying at -40oC and then loaded with EGCG. The proliferation of RASMCs cultured into EGCG-CM was significantly (p < 0.05) attenuated in spite of serum induction (reduction by about 30% after 3 d of cultures and 39% after 5 d). While RASMCs migrated toward CM in response to serum and populated it with essentially uniform ingrowth, EGCG-CM considerably blocked the cell migration after 3 d of incubation. These results suggest that reduction in the proliferation and migration of RASMCs induced by serum may be mediated through the inhibitory effects of EGCG released from CM
한동욱,박종철,김학희,이미희,손현주,백현숙,김현중 한국생체재료학회 2005 생체재료학회지 Vol.9 No.4
The polyphenolic compounds present in green tea show antimutagenic, anti-inflammatory and antitumorigenic effects in many cell culture systems and animal tumor models. Epidemiologic studies have also suggested that green tea consumption might be effective in the prevention of certain human cancers. In this study, the differential antiproliferative responses of green tea polyphenols (GTP) were investigated in fibroblast cell line (L-929 cells, from mouse connective tissue) and normal fibroblasts (from neonatal human dermis). GTP treatment (100 M for 24 h) resulted in significant (p < 0.05) inhibition of cell proliferation and morphological alterations with decreased local attachment, but not in normal fibroblasts. Cell cycle analysis revealed that the GTP treatment resulted in an appreciable G0/G1-phase arrest of the cell cycle in L-929 cells at 100 M concentration, while under similar experimental conditions, no evidence of G0/G1-phase cell cycle arrest was found in normal fibroblasts at the same dose. These results suggest that antiproliferative activity of GTP may be attributed to the differential regulation of cell cycle in fibroblast cell line and normal fibroblasts, which GTP may be exploited to craft strategies for the chemoprevention and/or therapy against cancer by GTP.