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Zhen‑Xing Li,Chang‑Sheng Li,Seong‑Hoon Kim,Dong‑Woo Suh 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.1
Effect of initial pearlite morphology on the microstructure evolution during spheroidization annealing and subsequent hardeningtreatment was studied in hot-rolled 1.0C–1.5Cr bearing steel. The ferrite-to-austenite transformation in spheroidizationannealing can be accelerated by refining the pearlite interlamellar spacing and pearlite colony size. Decreasing interlamellarspacing is also beneficial to increasing the number density of undissolved cementite, leading to the refining of final spheroidizedcementite. During the re-austenitizing process of hardening treatment, the smaller initial spheroidized cementiteleads to faster cementite dissolution and finer undissolved cementite particles. The prior austenite grain size after hardeningtreatment can also be decreased by refining the initial pearlite microstructure.
Dong-Dong Zhang,Jing-Lan Liu,Tie-Min Jiang,Lu Li,Guo-Zhen Fang,Yan-Pin Liu,Li-Jun Chen 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.3
With increasing application of yeast in fermented milk, in order to study the effect of yeast on milk protein during the fermentation process, the effects of the presence of Kluyveromyces marxianus in milk fermented by Streptococcus thermophilus and Lactobacillus bulgaricus were investigated. After fermentation, the amino acid, protein, and peptide contents were analyzed by ultra-performance liquid chromatography, two-dimensional gel electrophoresis, and liquid chromatography–mass spectrometry, respectively. After the addition of K. marxianus for fermentation, 25 protein spots changed significantly. These were mostly caseins and bovine serum proteins, and the content of total free amino acids increased by 16.30%; ten types of bioactive peptides were identified. Furthermore, the number of peptide types in milk fermented by K. marxianus increased significantly compared with milk fermented by Lactobacillus. K. marxianus is considered to promote proteometabolism in milk when added with Lactobacillus, generate flavor compounds, and improve the digestion and absorption character of milk.
Optimization for Cooling System of Batteries Having Porous Material Using Design of Experiments
Zhen-Zhe Li,Dong-Ji Xuan,Yong Li,Yun-De Shen 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.
A hybrid power composed of fuel cell and batteries has become the reasonable strategy for hybrid electric vehicles. On the contrary,the produced heat by batteries can affect the total performance of hybrid electric vehicles significantly. In this paper, analysis methodsand optimization strategy were constructed for obtaining the high performance cooling system for batteries having porous material. At first, a numerical method for obtaining the temperature distribution of battery pack including porous material was developed byusing CFD technique. In the following step, the cooling systems for batteries with porous material or not were compared for showingthe merit of the cooling system for batteries having porous material. Ultimately, an optimization strategy based on D-optimal DOEmethod was obtained through a real optimal design process. There was 13.3% reduction on the view of the root mean squaretemperature between batteries compared with the original cooling system for batteries as shown in the optimization result. Theconstructed analysis method and optimization strategy can be used to improve the performance of the cooling system for batteries,and these works have made the theoretical basis for simulation and optimization of the cooling system for batteries.
BanBan Li,Jia Lin Li,Na Li,Shi-Zhou Qi,이현선,Le Zhang,Shan-Shan Xing,Zhen Dong Tuo,Long Cui 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.11
Two new furofuran lignans were isolated fromthe stems of Acanthopanax senticosus, along with sevenknown compounds. Their structures were all determined byspectroscopic analyses and chemical methods. All theisolates were evaluated for in vitro inhibitory activityagainst DGAT1 and DGAT2. Compounds 1 and 2 werefound to exhibit selective inhibitory activity on DGAT1with IC50 values 89.5 ± 1.5 and 57.5 ± 1.3 lM,respectively.
( Ju-dong Li ),( Xin-fei Xu ),( Jiong-jie Yu ),( Zhen-li Li ),( Hao Xing ),( Han Wu ),( Han Zhang ),( Chao Li ),( Ming-da Wang ),( Meng-chao Wu ),( Wan-yee Lau ),( Tian Yang ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: A family history of liver cancer is regarded as a risk factor for hepatocellular carcinoma (HCC) development. We investigated the association between family history and cancer recurrence and survival in patients with hepatitis B virus (HBV)- related HCC. Methods: Patients who underwent curative resection of HBV-related HCC between 2003 and 2013 from a tertiary hepatobiliary center in China were enrolled in this study. A family history was defined as a self-reported history of primary liver cancer in the first-degree relatives. Propensity score matching (PSM) and multivariable Cox-regression analyses were performed to compare the overall survival (OS) and recurrence-free survival (RFS) between patients with and without a family history of liver cancer. Results: Of 1,112 patients, 183 patients (16.5%) had a family history of liver cancer. A family history was not associated with OS and RFS (P=0.994 and 0.428) in the entire cohort. Using PSM, 179 pairs of patients with and without a family history but with comparable baseline characteristics and operative variables were created. A family history was associated with decreased OS and RFS (P=0.042 and 0.006) in the PSM cohort. On multivariable Cox-regression analyses, a family history was significantly associated with decreased OS (HR: 1.574, 95% CI: 1.171-2.116, P=0.003) and RFS (HR: 1.534, 95% CI: 1.176-2.002, P=0.002) after adjusting for other prognostic factors. Conclusions: A family history of liver cancer was associated with decreased OS and RFS rates after curative resection in patients with HBV-related HCC.
( Liang Lei ),( Xin-fei Xu ),( Jiong-jie Yu ),( Ju-dong Li ),( Zhen-li Li ),( Jun Han ),( Han Zhang ),( Hao Xing ),( Han Wu ),( Ming-da Wang ),( Chao Li ),( Zheng Wang ),( Feng Shen ),( Meng-chao Wu ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: The prognosis of hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) is very poor. According to the BCLC treatment recommendations, sorafenib or other palliative treatment (PT) is recommended as the first-line therapy when it happens. In real world, however, a significant number of selected patients with HCC and PVTT suffered from surgical resection (SR). Methods: PubMed, Embase, Medline and Cochrane library were searched for studies comparing SR with PT (including TACE, sorafenib, etc.) for HCC with PVTT, which were published before September 2017. Results: 4,810 patients from 7 studies were enrolled in this meta-analysis, which divided into the SR group (n = 2,344) and the PT group (n = 2476). When compared with the PT group, the pooled hazard ratio (HR) for the 1, 3 and 5-year OS rates of the SR group were 0.56 (95% CI 0.52-0.60, P=0.03), 0.56 (95% CI 0.53-0.59, P<0.001) and 0.55 (95% CI 0.54-0.57, P<0.001). For subgroup analysis, when compared with the mere TACE group, the pooled HR for the 1, 3 and 5-year OS rates of the SR group were 0.54 (95% CI 0.43-0.67, P=0.81), 0.75 (95% CI 0.65-0.87, P=0.25) and 0.76 (95% CI 0.67-0.88, P=0.25). Conclusions: This meta-analysis demonstrated SR had better OS than TACE or other palliative therapy for HCC with PVTT. SR may be suitable as the first-line treatment for selected patients with resectable HCC and removable PVTT.
Zhen Chen,Han-lai Zeng,Haixia Li,Xueli Ma,Hongxia Dong,Dong Ma 한국유전학회 2014 Genes & Genomics Vol.36 No.6
The two-line system has been widely used inhybrid rice seed production, and the reverse photoperiodsensitivegenic male sterile line is a new germplasm withan opposite phenotype compared with normal photoperiodsensitivegenic male sterile rice. To better understand themolecular mechanisms of fertility regulation in reversephotoperiod-sensitive genic male sterile rice, a comparativeproteomic approach was used to analyze the proteinprofiles of three different tissues (young panicles, flagleaves and leaf sheaths) of D52S during the sensitive periodof pollen fertility transformation under sterile and fertileconditions. By quantitative analysis, 66 protein spotswere identified to be significantly changed in the threetissues. Bioinformatics analyses revealed that in sterilerice, a number of proteins involved in lignin-flavonoidbiosynthesis pathway were down-accumulated in panicles. The majority of proteins associated with energy metabolismwere down-accumulated in leaf sheaths while theproteins up-accumulated in leaves and leaf sheaths wereexclusively photosynthesis and defense related. Based onthe proteomics data, a short-day induced male sterilityprotein network was proposed. In addition, the genes ofselected protein spots were further analyzed by qPCR. These findings provide data for better understanding theregulation of pollen fertility in reverse photoperiodsensitivegenic male sterile rice, which could assist in thedevelopment of practical reverse photoperiod-sensitivegenic male sterile rice for large-scale crop breedingprograms.
Multiple Network-on-Chip Model for High Performance Neural Network
Dong, Yiping,Li, Ce,Lin, Zhen,Watanabe, Takahiro The Institute of Electronics and Information Engin 2010 Journal of semiconductor technology and science Vol.10 No.1
Hardware implementation methods for Artificial Neural Network (ANN) have been researched for a long time to achieve high performance. We have proposed a Network on Chip (NoC) for ANN, and this architecture can reduce communication load and increase performance when an implemented ANN is small. In this paper, a multiple NoC models are proposed for ANN, which can implement both a small size ANN and a large size one. The simulation result shows that the proposed multiple NoC models can reduce communication load, increase system performance of connection-per-second (CPS), and reduce system running time compared with the existing hardware ANN. Furthermore, this architecture is reconfigurable and reparable. It can be used to implement different applications of ANN.