환경적 측면에서의 공간개발 관계법 평가 및 개선방안 연구

백기영,황희연 永同大學校 2000 硏究論叢 Vol.6 No.1

본 연구는 지속가능하며 환경적으로 건전한 국토 공간개발을 도모하기 위한 제도적 개선방안 도출을 목적으로 한다. 이를 위해 우리 나라 주요 공간개발 관계법을 대상으로 문제점 분석과 평가 및 개선방안의 도출을 시도하였다. 평가 결과 현행 법규의 환경성이 미흡한 것으로 나타났으며, 특히 개발사업 관련법규와 산업입지 관련법규는 환경성 측면의 고려가 극히 미흡한 것으로 드러났다. 또한 국토이용제도의 환경보전형 개념정립을 위해서는 환경관리계획을 포용한 국토이용관리계획의 위상확립과 공간계획 관련법의 체계화가 중요하다는 점이 도출되었다. This paper examines the status quo of the existing space development laws and ordinances, and suggests institutional improvement devices and alternative orientations for the future application in environmentally sound and sustainable development. For this, we try to analyze the problems of major space development laws and ordinances and find out the proper evaluation and improvement system. As a results, the existing laws are insufficient in environmental standard it recommends improving the national land use system and systematizing laws and ordinances.

응급의학과 전공의 교육을 위한 제언

백광제,박승희,선경,장연희,엄병선,홍윤식 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Although the medical science in Korea has experienced remarkable development, both qualitatively and quantitatively, since its introduction at the beginning of the 20th century, its main focus has been on the expansion of spcialized treatment and medical care in general. However, the fast-paced economic development that started in the 1960's has caused substantial increases in cerbrovascular disease and coronary artery disease while the industrial development and in creased use of means of transportation have resulted in the rapid rise of incidents in external injuries. Consequently, the public has become acutelyh aware of the need for fast and effective emergency transportation and treatemnt. Such awareness also stems from the wide avalilability of medica care which is now established as a basic citizen's right as a result of the national medical insturance system that started in 1977 and was fully implemented in 1989. In response to the public demand for effetive emergency treatments, kthe health care sector has been making serious efforts to deliver better emergency treatments by expanding the emergency facilities and newly offering emergency training programs. Several hospitals have already commenced training programs in order to provide personnel specially trained in that area. The emergency medicine requires not only specialized training in the emergency treatment program in emergency should be designed in order to adapt to the specific needs of the Koreans, as based on epidemiological studies of the nature of emergency cases, its distribution in the population by ages and nature of injury, admission ratio, death rates, etc. currently prevailing in Korea. The present research has been carried out by the Korea university Hospital in preparation of the commencement of the emergency training program in 1994. The research consists of analysis of the emergency cases admitted in the Emergency center of Korea University Hospiatl from January 1992 to December 1992, its distribution, nature, and statistics regarding admission. Based on our research and our review of other available literature on the subject, we make the following suggestions regarding the specialized training program for emergency treatment. 1. The trainees must be required to be also t4rained in the areas of internal medicine surgery, obstetrics and pediatrics. 2. The training in internal medicine should include gastrointestinal, espiratory, cardiovascular medicine and nephrology which the training in surgery should include general surgery, neurosurgery and cardiac surgery. 3. The program should provide training for effective and accurate reading of the radiology. 4. The trainees should be required to participate in actural emergency treatment activities in order to have opportunities to acquire practical skills as well as theoretical knowledge. 5. The program should include course in medical management which would be necessary for effective management and administration of emergency centers and facilities. 6. The continued development of the program would require extensive studies and researches supported by the academic associations of medicine.

충북지역 도시방재계획의 도시계획적 진단과 발전방향 : 도시계획서 분석 및 전문가 의견조사를 중심으로

백기영,황희연,박병호,이만형,황재훈,류을렬 永同大學校 1999 硏究論叢 Vol.5 No.1

본 연구는 도시방재계획의 현황을 도시계획적 차원에서 진단하고 그 발전방향을 도출하고자 하는 목적하에, 충청북도의 조례와 지침중 도시방재 관련 사항을 정리하며, 충청북도 지방도시계획위원회 회의록 및 관련자료를 검토하여 방계계획의 취급 수준을 파악하였다. 실제 도시계획 상황에 대한 진단은 도시계획 보고서를 대상으로 도시방재계획의 위상을 분석하고 평가하였다. 또한 도시방재계획의 위상과 관련 전문가의 인식수준을 평가하고 이를 바탕으로 향후 바람직한 도시방재계획의 위상을 설정하기 위해 필요한 사항을 분석하고자, 도시방재에 관한 일반의식 수준, 도시재해에 관한 대처방안, 도시방재계획의 평가방향 등을 중심으로 설문조사를 실시하였다. 이상과 같은 충북지역의 방재계획에 대한 도시계획적 진단을 바탕으로 도시방재계획 관리체계의 방향 도출과 도시방재계획의 향후방향 제안을 시도하였다. This paper examines the status quo of the existing urban disaster prevention plans in Chungbuk Province and suggests alternative orientations for the future application. Its methodological themes center around the systematic compilation and accountability of disaster-related ordinances, mostly hinged on evaluation of major disaster items documented in various urban master or revision plans. In addition, it recommends the concrete guidelines and contents in disaster prevention plans, both of which are based on the aggregated results of expert opinion survey in and around Chungbuk Province. In order to tackle with diverse and unpredictable disasters which are well observed in modern urban society, this paper urges that the relatively weak legal and planning standards of the existing disaster prevention plans have to be immediately revised. For instance, the paper vividly shows that the present dimension of disaster prevention plans within the existing master plans and perception of specialist are not satisfactory mainly because of the internal limitation of the existing plans. Secondly, it seems imperative for planners to pay attention to systematic operation and management, even starting from the early development stage of urban disasters. Lastly, it proposes the alternative checklists given to measure the suitability of the disaster plans.

고삼 추출물을 이용한 해독물질의 개발

양희태,정승일,이영철,윤경아,백승화 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.1

고삼 메탄올 추출물로부터 분리한 flavonoids를 IR, NMR등의 분광학적인 방법으로 Leachianone A(LA)과 Sophoraflavanone G(SFG)로 동정하였고, 카드뮴의 세포독성효과를 고삼 및 고삼추출물이 방어할 수 있는 지를 검색하기 위하여 NIG 3T3 세포에 고삼 및 LA와 SFG, LA+SFG를 처리하고 MTT assay 및 광학현미경으로 세포의 생존률을 검색하여 다음과 같은 결론은 얻었다. MIT의 흡광도는 카드뮴의 농도에 의존하여 감소하였으며, IC_50인 MTT50은 12.5??이었으며 카드뮴을 IC_50농도로 처리하고 고삼 및 LA, SFG, LA+SFG를 각 화합물의 자체 세포독성을 갖지 않는 농도로 처리한 후 MTT assay로 세포 생존율을 측정한 결과 LA, SFG, LA+SFG 처리군들은 카드뮴 처리군(MTT_50)에 비해 세포생존률이 증가되었으며 이들은 고삼 및 고삼추출물의 농도에 의존적으로 증가되었고 각각의 단일 화합물보다 두 화합물 LA+SFG 병용처리군에서 수복 효과가 더 좋은 것으로 나타났으며 광학현미경적 소견에서도 세포재생이 뚜렷하게 보였다. 이상과 같이 고삼에서 분리한 flavonoids가 카드뮴 독성에 의하여 손상된 NIH 3T3 섬유아세포의 재생효과에 영향이 있는 것으로 판단된다. The aim of this study was to assess the antitoxic compounds, flavanones (Leachinanone A=LA and Sophora flavanone G=SFG), from Sophora flavescents (S. Flavescens). We investigated the possibility of antitoxicity of LA and SFG against NIH 3T3 fibroblasts cell lines using colorimetric MTT[3-(4-5-dimethylthiazol-2-yl)-2-5diphenyl-2H-tetra-azolium bromide] assay. The results were as follows : After cadmium was treated against NIH 3T3 cell lines, we determined IC_50. Accordingly we have examined the detoxification effects of S. flavescens, LA and SFG under cadmium IC_50=12.5?? and was carried out to observe morphological changes by the light microscopic study. In NIH 3T3 cells, Sophora flavescens, LA, SFG and LA+ SFG showed inhibitory effects on the cytotoxicity of cadmium and these detoxication effects increased in proportion to the concentration of these drugs. These results suggest that LA and SFG from S. flavescens retain a potential antitoxic activity.

Sludge를 이용한 자기 연마재 개발

김희남,윤여권,김상백,최희성,안효종 한국안전학회 2004 한국안전학회지 Vol.19 No.2

The magnetic polishing is the usefiil method to finish using magnetic power of magnet. This method is one of precision polishing techniques and has an aim of the clean technology using for the pure of gas and inside of the clean pipe for transportation. The magnetic abrasive polishing method is not so common for machine that it is not spreaded widely. There are rarely researcher in this field because of non-effectiveness of magnetic abrasive. Therefore, in this paper deals with development of the magnetic abrasive using sludge. In this development, abrasive grain WA and GC used to resin bond fabricated low temperature. And magnetic material was fabricated from the sludge which were crused into 200 mesh and average diameter 01.2mm ball type. The XRD analysis result show that only WA and GC abrasive and sludge crystal peaks detected which explains resin bond was not any more chemical reaction. From SEM analysis it is found that WA and GC abrasive and sludge were strong bonding with each other by bond.

냉기치료후 슬관절강내의 온도변화

백승석,최기섭,박시복,이상건,김영호,양길태,장윤희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

마우스에서 조합시험법에 의한 고려홍삼의 생식발생독성 평가

김미라, 박동선, 장자영, 신선희, 이예은, 백인정, 연정민, 이세라 , 남상섭, 황방연, 노재섭, 김순선, 조대현, 남상윤, 이범준, 김윤배, 윤영원 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.1

본문참조

고시 수재 의약품의 용출규격 설정 - 구연산니카메테이트 정, 노르플록사신 캡슐

김희연(Hee Yun Kim),최선희(Seon Hee Choi),방수진(Su Jin Bang),한경진(Kyung Jin Han),최승희(Sung Hee Choi),백지윤(Ji Yun Baek),김동섭(Dong Sup Kim),김영옥(Young Ok Kim),손경희(Kyung Hee Sohn),송영미(Young Me Song),사홍기(Hong Kee Sah) 大韓藥學會 2010 약학회지 Vol.54 No.5

Despite the fact that the dissolution test can serve as an effective tool for drug quality control and prediction of in vivo drug performance, there are a number of drugs with no established dissolution specifications because they were developed quite a long time ago. Under this circumstances, KFDA started the new project that establishes dissolution method and specifications for drugs with no dissolution specifications listed in the Korea Pharmaceutical Codex (KPC). This project aims for promoting the appropriate management of oral solid dosage forms. Seoul regional KFDA selected 2 items, Nicametate citrate tablet and Norfloxacin capsule, for establishing dissolution specifications. We went through the following procedures to develop the dissolution method and specifications: (1) Validation of dissolution test equipment, (2) Purchase of test drugs, (3) Preliminary test with one of the test products (1 lot), (4) Validation of analysis methods (3 lots), (5) Final tests and cross tests among other laboratory to establish dissolution specifications, (6) Additional test with the other test drugs. The outcome of this study will be reflected in revision of the KPC. It is believed that the quality control and evaluation of oral solid dosage forms listed in KPC will be advanced with the revision which adds additional dissolution test and specifications for the drugs with no established dissolution specifications.

Headspace Solid-Phase Microextraction Analysis of Volatiles in Floral Organs of Nelumbo nucifera

Yun Su Baek,Pue Hee Park,Hye Ryun An,Ramya Mummadi Reddy,Pil Man Park,Nam In Baek,Oh Keun Kwon 한국화훼학회 2016 화훼연구 Vol.24 No.4

The objective of this study was to identify the main floral scents and their relative contents in the floral organ of Nelumbo nucifera. N. nucifera flower, a traditional Chinese medicinal herb, is rich in volatile compounds. In this study, the volatile components of N. nucifera flowers were investigated by headspace solid-phase microextraction gas chromatography-mass spectrometry for each organ of the flower: petals, sepals, pistils, and stamens. In total, we identified 39 compounds, among which aliphatics were major constituents, representing more than 94% of petals and sepals volatiles, followed by sesquiterpenes representing more than 69% of pistils and stamens volatiles. Pentadecane, 1-pentadecene, 8-hexadecyne, 8-heptadecene, and β-caryophyllene characterize the scent of the N. nucifera flower. We identified 24 volatiles in petals and sepals, 25 volatiles in pistils, and 18 volatiles in stamens. Among the monoterpenes, 3-Isopropylidene-4-methylcyclohexene, isoterpinolene, p-Menth-2-en-7-ol, and methyl 2,6,6- trimethylcyclohex-1-enecarboxylate were analyzed and identified for the first time from the N. nucifera flower. This study demonstrates that N. nucifera flowers differ greatly in volatile composition depending on the floral organ of the plant.