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Rong-ling Yang,Xi Chen,Yu-ye Song,Qian-lin Zhu,Muhammad Bilal,Yu Wang,Zheng Tong,Ting-ting Wu,Zhao-Yu Wang,Hong-zhen Luo,Xiang-jie Zhao,Ting-ting He 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.3
Tyrosinase inhibitors are clinically effective for treating some dermatological disorders related to melanin hyperpigmentation. Accordingly, the discovery and development of tyrosinase inhibitors have great value in the pharmaceutical and cosmetic industry. Here, a novel tyrosinase inhibitor, 6′-O-cinnamoyl-helicid (helicid cinnamylate) was successfully synthesized by a simple and effective biocatalytic approach with Aspergillus oryzae cells. Investigation of the effects of several key variables on helicid cinnamylate synthesis found that the reaction conversion, reaction rate and regioselectivity reached 99%, 9.40 mM/h and > 99%, respectively, at the optimal conditions with anhydrous acetone as the solvent, whole-cell concentration of 40 mg/mL, and the molar ratio of vinyl cinnamate to helicid of 10 at 45°C. The whole-cells retained 68.87% of its initial activity after reusing for seven batches, indicating a potent application potential in non-aqueous biocatalytic systems. It was worth noting that helicid cinnamylate demonstrated a more potent tyrosinase inhibitory activity with an IC50 value of 3.55 mM than helicid (IC50 = 4.48 mM) and arbutin (IC50 = 5.48 mM), which suggest that helicid cinnamylate could be developed as a more potential tyrosinase inhibitor. In conclusion, this study provides a novel whole-cell catalytic approach for the synthesis of helicid cinnamylate and insight into its application as a tyrosinase inhibitor.
Yu-rong Deng,Qiu-li Wu,Wei Zhang,Ze-cheng Lv 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.5
Aiming at the provincial level within the grid wide-area distributed substation equipment on-line monitoring various types, processing of large amount of data and communication standard is not unified. Optimization of the structure of communication between the various levels, researched open communication format specification, established data interaction integration model. The paper studied the wide-area distributed on-line monitoring comprehensive processing unit of end stations with provincial level network of on-line monitoring system for the main platform of communication technology. Application shows that systems runs stability and meet online monitoring data collection, processing, transmission, and other functions, and has good maintainability and extensibility, adapt to various on-line monitoring in province level the development trend of the main platform for centralized management.
Optimal Trade and Privatization Policies in an International Mixed Market
Rong Yu,Sang-Ho Lee 서울대학교 경제연구소 2011 Seoul journal of economics Vol.24 No.1
This paper examines the optimal trade and privatization policies in an international mixed market where a domestic public firm competes against domestic and foreign private firms. We consider a trade policy combination of production subsidy and import tariff, and compare the optimal trade and privatization policies under either Cournot or Stackelberg competition. We find that the optimal trade policies consist of a domestic production subsidy and an import tariff, which are identical under the two regimes regardless of the competition pattern. However, the optimal privatization policy depends on the competition patterns, whether Cournot or Stackelberg competition. In particular, the optimal privatization policy under Cournot competition is complete privatization, whereas that under Stackelberg competition is full nationalization. Finally, we show that if the government can only use a single trade policy instrument, the production subsidy gives a better social welfare benefit than the import tariff.
청(淸)대 무술의 변천이 현대 중국무술체계에 미친 영향
육우용 ( Yu Rong Lu ),전익기 ( Ik Ki Jeon ) 한국체육사학회 2014 체육사학회지 Vol.19 No.2
본 연구는 청대 무술변천 중 군사무술, 민간무술 그리고 무술이론이라는 세 가지 부분을 구체적으로 살펴본 후 청대 무술의 변천이 현대 중국무술체계에 미친 영향을 알아보고자 하였다. 청대의 고대 전쟁에서 결정적인 요인이었던 군사무술변천은 시대 흐름에 따라 종결되었지만 군대에서만 수련하는 군사무술이 민간으로 대량 유입되고 보급되어 민간무술 변천을 하였다. 민간무술의 경우는 청왕조를 대항하는 조직들의 무술활동이 청대 무술변천에 중요한 촉진의의가 있다. 또한 청말의 무술이 체육화(體育化)로 변천하기 시작하였기에 무술의 새로운 발전방향을 모색하였다. 그리고 청대는 중국 무술의 이론적인 내용이 체계화 되고 그 당시 나타난 무술사상들과 집필된 무술저서들은 중국 무술의 수련 및 이론 연구에 매우 중요한 사료가 되었다. The purpose of this study is to verify the impact of and modification of martial arts in Qing dynasty on modern Chinese martial arts system after reviewing 3 sectors of military martial arts, private martial arts and martial arts theory. Military martial arts flowed into among people and spread out to eventually evolve private martial arts though the development of military martial arts as a decisive victory factor in wars at Qing dynasty was terminated as time passed by. Organizations against Qing dynasty promoted the development of private martial arts and martial arts were transformed into physical education to seek a new development direction at the end of Qing dynasty. The theory of martial arts was systematized in Qing dynasty and the philosophy and writings of martial arts in those days became important historical records for martial arts training and theoretical research.
영옥(Rong Yu),양은경(Eun-Kyung Yang) 충남대학교 사회과학연구소 2020 사회과학연구 Vol.31 No.2
This study examined the emotional characteristics of China’s most popular social media, Weibo, recognizing that online media are based on algorithms that enable them to produce emotional content actively and have a great social impact. First, the anger that appears in the discourses of users produced and distributed in Weibo is more of a self-destructive emotion that is enjoyed by criticism itself or expressed in ridicule and cynicism, rather than improving or reforming reality. Second, Weibo users disparage various socially underprivileged groups, and at the same time, insist on absolute egalitarianism in recognition that the victims or underprivileged are theirs. Conflict and hostility between middle and lower classes with the same social position are accelerating, targeting the minority and underprivileged groups of society, not the privileged vested groups, who have the privilege of being angry. Third, not only gender conflicts in the Weibo space, but also mutual criticism and aversion among generations, classes, and groups are found, ranging from political elites, generations, races and ethnicities, and groups with different tastes. To mitigate the emotional structure of the ressentiment, one must recognize that these emotions are not limited to specific generations and groups, and through policies to produce stable living conditions rather than criticism and regulatory-driven responses. Overall, efforts to reduce feelings should be given priority.