직장 카르시노이드 종양에서 Ki-67 발현의 예후적 중요성

홍수민 ( Su Min Hong ),김유선 ( You Sun Kim ),문정섭 ( Jung Seop Moon ),김진남 ( Jin Nam Kim ),오명기 ( Myoung Ki Oh ),권선옥 ( Sun Ok Kwon ),정성연 ( Seong Yeon Jeong ),홍성우 ( Seong Woo Hong ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2

Background/Aims: Rectal carcinoid tumors can be resected with endoscopy, and it is important to assess their prognostic factors. We evaluated the potential of Ki-67 expression as a prognostic factor in rectal carcinoid tumors. Methods: We retrospectively reviewed the medical records of 37 patients with rectal carcinoid tumors who got endoscopic resection from January 2001 to January 2011 at Inje University Seoul Paik Hospital. We analyzed their endoscopic and histologic findings, Ki-67 expression, clinical outcome, and prognosis. Results: The mean age (±SD) of the patients was 56.3±10.7 years, and the male : female ratio was 3.6:1. The mean tumor size was 0.5±0.4 cm, 33 patients showed grade 1 tumors (89.2%) and the average Ki-67 expression was 0.7±1.2%. Thirty five patients underwent endoscopic mucosal resection, and two required endoscopic submucosal dissection. Eight patients had positive margins after resection, but no cases of lymphovascular invasion were identified. The median follow-up duration was 21.4±25.4 months, and no recurrences were observed. Conclusions: In low grade rectal carcinoid tumors which are lack of central depression on colonoscopy, the expression of a molecular marker of malignant potential, Ki-67, was low. Therefore, endoscopic resection seemed to be a safe and effective treatment for these tumors.

열처리된 ZnO:Al 투명 도전막의 전기적 및 광학적 특성

유권규,김진해,전춘배,김정규,박기철 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

The heat treatment effects of the undoped ZnO and Al doped ZnO(ZnO:Al or AZO) transparent conductive films prepared by rf magnetron sputtering were investigated. The variations of the electrical and optical properties with heat treatment temperature and ambient gas or conditions were studied. The resistivity of the undoped ZnO films, heat-treated in air, vacuum and H_(2) plasma for 1 hour, increased rapidly above 200 ℃ , 300 ℃ ,400 ℃ and 400 ℃, respectively. And the resistivity of the ZnO:Al films heat-treated in air also increased rapidly above 300℃ . On the other hand the resistivity of the ZnO:Al films heat-treated in vacuum and H_(2) plasma were observed constant resistivity regardless of heat treatment temperature. The optical transmittance above 550nm is about 90% for all films regardless of impurity doping, the heat treatment temperature and ambient gas or conditions.

ZnO:In 박막 NH₃가스센서의 제작 및 특성

김진해,유권규,전춘배,김정규,박기철 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

Amonia gas sensitive ZnO:In thin films were prepared by In(100 Å)/ZnO(3000 Å) double layer deposition onto the Si-wafer substrate thermally grown with 1000 A SiO_(2) and the subsequent heat treatment process. Dependence of the sensitivity and selectivity of them on heat treatment temperature was investigated. The thin film heat-treated at 400 ℃ showed the highest sensitivity at an operating temperature of 300 ℃. The selectivity towards CO, NO_(x) gases was observed in the same temperature.

주의력결핍-과잉행동장애를 동반한 알코올 의존환자들의 특성 : 임상적/유전학적 자료분석

김붕년,손기현,전지현,곽욱환,유희정,조수철,박철수 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.3

Objectives : This study was conducted to estimate the comorbidity rate of ADHD in a group of patients with alcohol dependency and to find out the characteristics of alcoholic patients with ADHD using the diverse clinical and genetic variables. Methods : Eighty five patients with alcohol dependency were recruited from 4 mental hospitals in Kyoung-Nam and Kyoung-Ki province. For the evaluation of ADHD symptoms in both childhood and adulthood, the highly structured Diagnostic Interview Schedule for Children-IV (DISC-FV)-ADHD module was used. The various standardized scales and questionnaires were also applied to evaluate the comorbid conditions and psychopathological status. All the subjects' blood was collected and genetic study for the polymorphism of DRD2, TH, 5-HTTLPR, COMT, ALDH2 was performed. Results : 1) The comorbid rate of definite ADHD in alcoholic patients was 38% (28/85). 2) The frequency of unmarried status was significantly higher in ADHD group compared non-ADHD group. 3) The onset of pathologic drinking and auditory hallucination was significantly earlier in ADHD group than non-ADHD alcholic group. 4) In ADHD alcoholic group, antisocial behavior was more frequently reported, and the score of co-dependency scale, depression/anxiety, aggression and obsessive compulsive drinking scales were significantly higher compared to non-ADHD alcoholic group. 5) No signficant difference was found in the frequency of polymorphic alleles in COMT, DRD2, 5-HTTLPR, ALDH2, TH between ADHD and non-ADHD alcoholic group. Conclusion : In alcoholic patients, the rate of adult type ADHD was higher than expected rate in general population. The alcoholic patients with ADHD suffered from more sever degree of alcohol dependency and earlier alcohol related problems. ADHD-alcoholic group showed higher diverse comorbid psychopathology and lower marital status compared to non-ADHD-alcoholic group. No difference, however, was found in genetic data between two groups.

만성 신장 질환인 2마리의 개에 있어서 외인성 크레아티닌 청소율 검사에 의한 사구체 여과율 측정 예

강지훈, 강건아, 김유정, 나기정, 양만표 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.1

본문참조

초등학교 고학년 학생의 장애아동에 대한 인식 조사

김보람,김호영,손유라,오진주,윤슬기,이효정,장문영 대한감각통합치료학회 2011 대한감각통합치료학회지 Vol.9 No.1

목적 : 초등학교 고학년 학생의 장애아동에 대한 인식을 알아보는 것이다. 연구방법 : 연구 대상은 김해시에 소재한 통합교육을 실시하지 않는 초등학교의 4, 5, 6학년의 비장애 아동이었다. 연구 기간은 2008년 10월 2일부터 10월 17일까지였으며, 설문지를 사용하였다. 설문지의 하위 영역은 사귐, 활 동, 학업 영역의 세 부분으로 각 10문항으로 이루어져 있으며 SPSS 12.0을 사용하여 분석하였다. 결과 : 장애아동에 대한 인식조사 결과 첫째, 성별에 따른 인식은 남학생보다 여학생의 평균 점수가 높았으나 통계 적으로 유의미한 차이는 없었다. 둘째, 학년에 따른 인식은 4학년의 평균 점수가 가장 높았고 6학년이 가장 낮았으 며 통계적으로 유의미한 차이가 있었다(F=3.546, p<0.05). 셋째, 장애인 접촉 유무에 따른 인식은 접촉 경험이 없 는 학생이 있는 학생보다 평균점수가 높았으나 통계적으로 유의미한 차이는 없었다. 결론 : 비장애학생의 장애아동에 대한 인식은 학년에 따라 차이가 있었다. 본 연구는 작업치료사들에게 장애아동에 대한 또래집단의 인식에 대한 정보를 제공함으로써 학교환경에 대한 이해를 도울 수 있을 것이다. Objective : The purpose of this study was to investigate attitude of grade-schoolers toward children with disabilities. Methods : The subjects of this study were grade-schoolers who have not received an inclusive education in Gim-hae. The study was surveyed from October second to 17th in 2008. The survey was categorized into three parts; comradeship, activity, and study. Each part of the survey consists of 10 questions. Data were analyzed by SPSS (version 12.0). Results : The results were as follows; First, the attitude of girls toward disabled students was non-significant compared to boys. Second, the order of attitude degree in grade of students was 4, 6, and 5. The attitude toward children with disabilities showed statistically significant difference according to grade(F=3.546, p<0.05). Third, the attitude of students who have experience of contact with people with disabilities was non-significant compared to non-experienced students. Conclusion : In conclusion, therefore peer groups in lower class levels showed more positive attitude toward the children with disabilities. The result will be useful information for understanding disabled children and making positive attitude. Also it is expected that occupational therapists help disabled children to participate in school life successfully using these information.

京畿道의 植物相 : 태화산, 화야산, 대부도, 칠현산, 철마산, 검단산

崔道烈,張珍成,金正猷,全正壹,金輝,閔雄基,姜佑昌 서울대학교 수목원 2001 서울大學校 樹木園 硏究報告 Vol.- No.21

This study was conducted in order to explore general flora of the Gyounggi-do Province and to clarify the distribution of some specificated taxa of the Korea. Daebu-do Island, Mt. Taewha, Mt. Hwaya, Mt. Gumdan, Mt. Chilhyun and Mt. Chulma among eighth grade-area of the Degree of Green Naturality (DGN) within the boundary of the Gyounggi-do Province were visited to investigate local flora. The number of identified vascular plant species were as follow; Mt. Hwaya: 120 species (99 genera of 67 families), Mt. Teawha: 132 species (103 genera of 56 families), Daebu-do Island: 124 species (103 genera of 50 families), Mt. Chulma: 129 species (99 genera of 67 families), Mt. Gumdan: 121 species (96 genera of 52 families), Mt. Chilyun: 90 species (74 genera of 42 families). The endemic Clematis brachyura Maxim. was found to distribute Daeby-do. It seemed that plantation was occupying large area in forest of the Gyounggi-do Province. Forty two specificated taxa were identified and 3 taxa, 10 taxa, 5 taxa, and 24 taxa were sorted into forth grade, third grade, second grade, and first grade respectively. Mt. Taewha showed the highest record (16 taxa) in the number of specificated taxa, Mt. Hwaya was the next with 13 taxa. Mt, Chulma (12 taxa), Mt. Gumdan (11 taxa), Daebu-do Island (7 taxi), and Mt, Chylma (4 taxi) followed. Mt. Taewa and Mt. Whaya were found to be relatively higher in the score calculated front the specificated taxa distribution, while Daebu-do Island and Mt. Chilyun were lower, that difference was probably due in part to consequences of severe disturbance of human activities. With respect to the consequences of severe disturbance of human activities. With respect to the geographical proximity to the Gangwon Province, Mt. Hwaya showed higher similarity of the species composition to that of the Mt. Jumbong.

급성충수돌기염으로 발현된 방선균증 2예

조진원,송진영,김창억,민영훈,최창순,우흥정,현인규,김종현,유기철,채승완,손진희 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

The Actinomyces species are normal flora of oral cavity and upper intestine characterized as gram-positive, non-spore-forming anaerobic or mjcroaerophilic rods. Actinomycosis is a chronic suppurative and granulomatous disease characterized by abscess, sinus, abundant granulation and mass. The appendix is the commonly involved site among abdominal actinomycosis. Abdominal actinomycosis is often difficult to diagnose before operation because of no reliable clinical features and infrequency of the disease. We report two cases of abdominal actinomycosis which were manifested as acute appendicitis. Those were detected Incidentally tv the pathologist after routine appendectomy. Both patients were successfully treated with appendectomy followed by proper antibiotics use.

인천 인현동 호프집 화재 피해자 분석

최정태,안무업,안희철,최영미,정재봉,서정열,유기철,이삼우,박석현,조준휘,김성환,김아진,송근정 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Purpose : This study was conducted to develop field triage, transportation, distribution, and prehospital care at a fire disaster by analyzing the victims of the fore that broke out at a bar in Incheon. Method : We analyzed the cases of the victims of a fire in Incheon in Oct. 1999. We determined the primary care hospital, the arrival time, the burn size, the outcome, and the injury type from the medical records, the concerned organ records, and interviews with concerned persons. Result : The total number of victims was 137: 56 prehospital deaths, 1 hospital death, and 80 survivals. The Pearson correlation coefficient between the burn size and the severity was -0.175. There were 121(89.6%) cases of inhalation injury, 59 (43.7%) cases of flame burns, 66 (48.9%) cases of hypoxic brain damage, and 16 (11.9%) cases involving other types of injury. Conclusion : The causes of death of the fire victims were inhalation injury and hypoxic brain damage due to CO poisoning and other toxic inhalants. We propose the use of a simple triage and rapid treatment(START) system and a reassessment the delayed category in fire disasters.

Acute Left Main Coronary Artery Occlusion by Embolization of Vegetation in Patient With Infective Endocarditis

You-Jeong Ki,우종신,김원 대한심장학회 2022 Korean Circulation Journal Vol.52 No.12