Ultrasonic Degradation of Endocrine Disrupting Compounds in Seawater and Brackish Water

So Young Park,Jong Sung Park,Ha Yoon Lee,Ji Yong Heo,Yeo Min Yoon,Kyung Ho Choi,Nam Guk Her 대한환경공학회 2011 Environmental Engineering Research Vol.16 No.3

In this study, a series of experiments was conducted on the relative degradation of commonly known endocrine-disrupting compounds such as bisphenol A (BPA) and 17α-ethinyl estradiol (Ee₂) in a single-component aqueous solution using 28 and 580 kHz ultrasonic reactors. The experiments were conducted with three different types of model water: deionized water (DI), synthetic brackish water (SBW), and synthetic seawater (SSW) at pH 4, 7.5, and 11 in the presence of inert glass beads and humic acids. Significantly higher sonochemical degradation (93-97% for BPA) occurred at 580 kHz than at 28 kHz (43-61% for BPA), regardless of water type. A slightly higher degradation was observed for Ee₂ compared to that of BPA. The degradation rate of BPA and Ee₂ in DI water, SBW, and SSW after 30 min of ultrasound irradiation at 580 kHz increased slightly with the increase in pH from 4 (0.073-0.091 min-1 for BPA and 0.081-0.094 min-1 for Ee₂) to 7.5 (0.087-0.114 min-1 for BPA and 0.092?0.124 min-1 for Ee₂). In contrast, significant degradation was observed at pH 11 (0.149-0.221 min-1 for BPA and 0.147-0.228 min-1 for Ee₂). For the given frequencies of 28 and 580 kHz, the degradation rate increased in the presence of glass beads (0.1 mm and 25 g) for both BPA and Ee₂: 0.018-0.107 min-1 without beads and 0.052-0.142 min-1 with beads for BPA; 0.021-0.111 min-1 without beads and 0.054-0.136 min-1 with beads for Ee₂. A slight increase in degradation of both BPA and Ee₂ was found as the concentration of dissolved organic carbon (DOC, humic acids) increased in both SBW and SSW: 0.107-0.115 min-1 in SBW and 0.087-0.101 min-1 in SSW for BPA; 0.111-0.111 min-1 in SWB and 0.092-0.105 min-1 in SSW for Ee₂. After 30 min of sonicating the humic acid solution, DOC removal varied depending on the water type: 27% (3 mg L-1) and 7% (10 mg L-1) in SBW and 7% (3 mg L-1) and 4% (10 mg L-1) in SSW.

대장내시경검사의 전처치로서 항콜린제 사용에 관한 연구 : 전향적, 이중맹검법으로

박경남,한동수,이민호,최호순,박준용,손주현,이오영,함준수,전용철,송승찬,기춘석,윤병철,이종희 대한소화기내시경학회 1997 Clinical Endoscopy Vol.17 No.3

Background: Use of antispasmodic medication prior to colonoscopy is controversial but someone believes antispasmodic may improve visualization of colonic mucosa and ease colonoscope insertion. So, we designed a study to assess the effect of premedication with the antispasmodic, hyoscine-N-butyl bromide(Buscopan') on the performance of colonoscopy. Methods: This study was prospective, double blinded, randomized, controlled study, One hundred three consecutive patients were randomized to receive intravenous buscopan lml(n=52) or placebo(n=51) combined with our standard initial medication(me- peridine 50 mg and midazolam 2 mg). Insertion of colonoscopy was timed, and 100 mm visual analogue scales (VAS) were used for asscssing difficulty of procedure, colonic motility, frequency of positional change, frequency of external compression, difficulty of assistance and degree of discomfort experienced by the patients. Results: There were no significant differences of intubation time between buscopan group(mean time, 7.23 min., range 2~15) and placebo group(7.07 min., range 3-25), (p=0.83) and withdrawal time between buscopan group (6.46 min., range 2-22) and placebo group(6.76 min., range 2 25), (p=0.69). Also, there was no significant differences in intubation time between males and females(buscopan; males 7.00 min., females 7.60 min., p=0.34, placebo; males 7.0~5 min., females 7.08 min., p 0.44). The VAS scores checked by endoscopist(p=0.29), assistant(p=0.32) and patient (p=0.15) were not significantly different in both groups. There were no significant differences in intubation time, VAS scores nf endoscopist, assistant, and patients. Conclusion: Premedication with intravenous bu.opan has no advantage on colonoscopy procedure. Use of antispasmodic medication prior to colonoscopy was not considered as recommendable agent.

팔당호의 생태학적 수질환경의 변화와 미생물 분포

허성남,민경희,유재근,최순영 숙명여자대학교 자연과학연구소 1999 자연과학논문집 Vol.- No.10

팔당호의 생태학적 환경요인의 계절적인 변화를 분석하므로서 이것으로 인한 식물성 플랑크톤의 연관성을 고찰과 함께 오염과정을 파악하여 수질오염의 예방의 기초자료를 얻고자 본 실험을 수행하였다. 1994년 4월부터 1995년 10월까지 계절별로 3개 지점에서 시료를 채취하여 표층부와 저층부의 수질을 분석하였다 용존산소(DO)와 pH는 각각 7.0-11.6 ㎎/ℓ와 6.9-8.9의 범위이었으며 COD와 BOD농도는 각각 1.6-4.8 ㎎/ℓ와 0.8-2.9 ㎎/ℓ이었으며,SS는 1.8-8.6 ㎎/ℓ의 농도차를 보여 주었다. 또한 NH₃-N와 PO₄-P의 농도는 각각 0.161-0.478 ㎎/ℓ와 0.003-0.073 ㎎/ℓ이었다. 표층의 chlorophyll a의 농도는 낮게는 북한강 유입부위인 12.3 ㎎/ℓ로부터 가장 높은 경안천 유입부위 23.8 ㎎/ℓ의 범위를 보여주고 있다. pH,전도도, COD, BOD, SS ,총인, chlorophyll a의 농도는 하계절에 가장 높았으며 이 결과로 미루어 보아 하계절에는 하천에 오염물질이 가장 많이 유입되는 것으로 추정된다. Station별로 조사한 결과 이들의 농도는 경안천 하류인 St. 3가 남한강 하류인 St. 2이나 댐지역의 St. 4보다 높은 결과를 보여 주었으므로 경안천 상류에서 오염원이 가장 많이 유입되는 것으로 추정된다. 아울러 종속영양세균의 분포도 경안천이 다른 지역보다 가장 높게 나타났다. Seasonal variation of water quality was examined in the reservoir, lake Paldang on Han River, the inlet stations from three rivers, North Han River, South Han liver, Kyung-An stream, and the station of dam area of the lake. Water samples were collected bimonthly from surface and bottom layers at four different stations of the lake Paldang from April 1993 to August 1994. With respect to the seasonal variation, pH, conductivity, and concentrations of COD, BOD, SS, total phosphorus, and chlorophyll a were higher in summer compared with those of autumn or other seasons, while concentrations of DO, NH₃-N, and PO₄-P were increased in winter. Concentrations of COD, BOD, chlorophyll a, total nitrogen and phosphorus were the highest at the station of Kyung-An stream rather than those of other three stations. The average concentrations of chlorophyll a surface water were from 12.3 ㎎/ℓ at North Han River to 23.8 ㎎/ℓ at Kyung-An stream. Heterotrophic bacterial distribution showed higher at the station of Kyung-An steam than those of South Han River and the dam station of the lake.

치과용 임플란트 적용을 위한 항균력을 가진 티타늄 표면의 평가

강민경 ( Min Kyung Kang ),문승균 ( Seung Kyun Moon ),김경남 ( Kyoung Nam Kim ) 한국치위생과학회 2011 치위생과학회지 Vol.11 No.5

The aim of this study was to evaluate antibacterial effect of Cl coated titanium. To coat the Cl on the titanium, first, the titanium was modified by blasting treatment with hydroxyapatite and alumina powder. Anodization process was completed using electrolyte solution of 0.04 M β-glycerol phosphate disodium salt n-hydrate, 0.4 M calcium acetate n-hydrate and 1 M NaCl on the condition of 250 voltages for 3 min. Surface morphology and elements` observation were performed with scanning electron microscopy and energy dispersive spectroscopy and surface profiler was used to analyze the surface roughness. Antibacterial effect was evaluated by film adhesion method. The anodized titanium after blasting showed dimpled surface contained the Cl. Surface average roughness of these surfaces had significantly higher compared to polished titanium. Result of antibacterial test showed that anodized titanium after blasting had an enhanced antibacterial effect compared to the polished titanium. Therefore, these results suggested that titanium contained Cl by anodization after blasting had a rough surface as well as antibacterial effect.

정상체중군과 과다체중군 산업장 중간관리자의 건강증진 행위에 관한 비교연구

김정남(Kim Chung Nam),박경민(Park Kyung Min),류미경(Ryu Mi Kyung),장희정(Jang Hee Jung) 계명대학교 간호과학연구소 2001 계명간호과학 Vol.5 No.1

The purpose of this study was to identify and compare Health Promoting Behavior and its affecting factors between Normal and Over weight industrial middle manager. The subjects were 163 workers employed in factories in Taegu and Kyung-book were convenient sampling data the period for May 22th-26th, 2000 through self report methodby structured questionnaires. Collected data were analyzed by t, x2, Kendal tau, Pearson correlation, Stepwise Multiple Regression. The results of this study were as follows. 1. There were a significant difference in shift pattern(x2=7.89, P=0.005) and career. (x2=12.99, P=0.005) between normal weight and overweight group. 2. The average score of performance in health promoting behavior among overweight group(2.55) was higher than that of normal weight group(2.46), but not significant. 3. The average score of health status in overweight group(3.07) was lower than that of normal weight group(3.21), but not significant. 4. The average score of self-efficacy in overweight group(3.63) was significant lower than that of normal group(3.71). 5. The average score of the perceived barrier of in overweight group(2.44) was significant higher than that of normal group(2.24). 6. Health promoting behaviors in overweight group was significantly correlated with health status(r=.384, P<.05), health Concept(r= 458, P<.01) self-efficacy ( r=352, P< 01), perceived benefit(r=.386, P< .05), perceived barrier(r= -245, P< .05) Health promoting behavior in normal weight group was significantly correlated with health concept( r= .307, P< .050 and perceived benefit. 7. In consideration of variables that have an influence on Health promoting behavior among Normal weight group, health concept and perceived benefit account for 28.8% of health promoting behavior. In overweight group. The perceived benefit account for 13.7% of health promoting behavior. The suggestions are as follows on the basis of the results of this study. 1. It is required to develop health promoting program to improve health promoting behavior. In addition, there are special demands on developing nursing strategies for health promoting behavior of overweight industrial supervisors. 2. It is necessary to support exercise facility in occupational field for improving supervisor's health promoting behavior.

간질환환자의 위내용물 배출시간에 관한 연구

함준수(Joon Soo Hahm),이동후(Dong Hoo Lee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이종철(Jong Chul Rhee),기춘석(Choon Suck Kee),유대현(Dae Hyun Yoo) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2

N/A Gastric emptying time(GET) is influenced by several factors, such as neura), hormonal and composi- tion and physiochemical properties of food. The patients with delayed GET have some upper gastrointestinal symptoms such as recurrent nausea, vomiting, postprandia! Bloating, anorexia, and iveight loss. And also, almost of acute hepatitis and a part of chronic ]iver disease patients have similar symptoms of the patients with delayed GET. Therefore We performed GET measurement in liver disease patients to identify the relationship between nonspecific upper gastrointestinal symp- toms and gastric emptying function. The resu]ts are as followings; 1) Total ]iver disease patients are 28 in number, composed of acute hepatitis 3, chronic hepatitis 18, liver cirrhosis 7. 2) The GET(T1/2) of liver disease patients was delayed significantly than that of the normal volunteers. (Mean+SE;120.8+6.6 vs 89.4+5.9 mins.) 3) The GET of the symptomatic patients (N = 20 ) ivas 128.3+6.8 mins (Mean+SE), and that of the asymptomatic patients (N =8) was 101.8+13.2 mins. The symptomatic patients have delayed GET in 10 patients and asymptomatic patients have delayed GET in 3. 4) The GET of the patients who have elevated serum transaminase level higher than twice of normal is delayed significantly than that of the patients who have serum transaminase level lower than twice of normal. (Mean+SE; 143.4+2.6 vs 110.0+7.4 mins.)

목표과정중심교육과정(PPCF)에 의한 중학교체육교사들의 체육목표인식도 연구

민경훈,박종남 서강전문대학 1994 論文集 Vol.13 No.-

The purpose of this study is to find the middle school teachers' perceptions of physical education objectives through background PPCF(Purpose Process Curriculum Framwork).The subjectives(N=123) were collected elementry school teachers in Kwang Ju city and Chunnam province and were administerd the PPCF questionaire developmented by Jewett that was constructed physical efficiency, psychic equilibrium, spacial orientation,objest manipulation, communication, group interaction, and cultural involvement. The results were as followa; 1. Middle school teachers' perception of physical education was more than average in all subpurposes and perceived group interaction to be most important. 2. The teachers of rural province perceived more significantly important than the subpurpose of communication,but there was not different any other subpurpose between them. 3. There were not different any other subpurpose between career groups( less than 5 years career group,from 6 to 10 years career group,more than 11 years career group).

다양한 적송잎 추출물의 항생제 내성 황색포도상구균에 대한 항균활성 검증

Nam-Young Kim(김남영),Min-Kyung Jang(장민경),Myung Je Jeon(전명제),Dong-Geun Lee(이동근),HyeJi Jang(장혜지),Seung Woo Lee(이승우),Mihyang Kim(김미향),Sung Gu Kim(김성구),Sang-Hyeon Lee(이상현) 한국생명과학회 2010 생명과학회지 Vol.20 No.4

병원 내 감염의 주된 원인균으로 알려진 황색포도상구균(5. aureus)과 항생제 내성 황색포도상구균(PRSA, MRSA)에 대해 항균활성이 우수한 천연 항균성 물질을 검색하기 위해 적송잎을 대상으로 열수-헥산(HWH), 열수-에탄올(HWE), 헥산, 에탄올 및 열수 등으로 획득된 추출물들로 항균활성을 조사하였다. 헥산, 에탄올, 열수-헥산, 열수-에탄올 추출물들은 그람양성 대표세균인 고초균(B. subfilis), 황색포도상구균 표준균주, 항생제 내성균주인 PRSA 및 MRSA에 대해서 항균활성을 나타내었으며, 특히 MRSA (ATCC 33591) 균주에 대해 다른 균주들 보다 높은 항균활성을 나타냈다. 열수 추출물은 황색포도상구균 표준균주 및 MRSA에서만 항균활성을 나타냈지만, 항균활성은 가장 높아 50 ㎎/㎖의 농도에서 33 ㎜의 생육저해환을 나타냈다. 각 균주들에 대한 생장의 최소저해 농도(MIC)는 HWH 및 HWE 추출물이 모두 0.05 ㎎/㎖의 농도로 가장 낮았고, 열수추출물이 0.5 ㎎/㎖의 농도였으며, 에탄올 추출물은 5 ㎎/㎖의 가장 높은 농도를 나타냈다. 모든 추출물들은 121℃에서 20분간의 열처리 후에도 항균활성이 유지되었으므로 열에 대해 안정한 물질임을 알 수 있었다. 본 연구결과로 식품산업에서 솔잎 추출물을 천연 항균제로 사용할 수 있을 것으로 기대할 수 있다. investigated antimicrobial activities of various pine (Pinus densiflora) needle extracts against antibiotic resistant strains of Staphylococcus aureus. Hot water extract showed the highest antimicrobial activity against normal and methicillin resistant Staphylococcus aureus (MRSA), however, it exhibited no antimicrobial activity against penicillin resistant S. aureus (PRSA). Hot water-hexane (HWH), hot water-ethanol (HWE), hexane, and ethanol extracts showed antimicrobial activity against S. aureus, PRSA and MRSA. Minimum inhibitory concentrations (MIC) of HWH, HWE, hexane, and ethanol extracts were 0.05, 0.05, 0.5 and 5 ㎎/㎖ respectively, and HWH and HWE extracts showed the strongest antimicrobial activity among these extracts. Antimicrobial activities of pine needle extracts were stable after heating at 121℃ for 20 min. These results suggested that pine needle extracts can be used as an effective natural antimicrobial agent for food and medical industries.

철결핍성빈혈 진단과 RDW, MCV

민해연,강연주,조경진,남영미 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCINE 1995 Journal of biomedical laboratory sciences Vol.1 No.1

자동혈구계산기에서 산출되는 RDW나 MCV가 철결핍성빈혈의 구분진단에 어떠한 도움이 되는지를 보기 위하여 어는 대학병원의 최근 5년 동안의 의무기록과 건강진단결과를 이용하여 227명의 빈혈환자와 143명의 건강인을 선정하고 그들의 혈액검사 결과를 비교분석해 보았다. 분석결과 빈혈환자로서는 철결핍성빈혈과 재생불량성빈혈 환자가 많았으며, 그 외에 만성질환과 관련된 빈혈환자도 많은 것으로 나타났다. 정상인 들에 비하여 빈혈환자에서 RDW는 높게, 그리고 MCV는 낮게 나타났는데 특히 철겹핍성빈혈에서는 다른 빈혈에 비하여 19.3±4.8로 현저하게 높게 나타난 반면, MCV는 62.9±13.7fl로 현저하게 낮게 나타났으며, 그 빈혈의 정도에 따라 그 변화가 크게 나타났다. 빈혈관련수들을 이용하여 D.F.=0.26-0.012MCV-0.130MCH+0.073MCHC+0.052RDW+0.003PLT와 같은 판별함수가 도출되었고, 이를 토대로 철결핍성빈혈과 다른 빈혈을 구분하는데 있어서는 MCV, MCH, MCHC, RDW등이 판별력이 있다는 것을 확인 할수 있었다. RDW and MCV are thought to be the highly sensitive blood cell parameters in the differentiation of iron deficiency anemias. Through the medical records of 227 anemic patients and the physical checking results of 143 healthy persons in a General Hospital during the recent five years, the authors evaluated various blood cell parameters including RDW and MCV. Iron deficiency anemia, aplastic anemia and other anemias associated with chronic discase were shown as the three major causes of anemias in Korea. In the patients of iron deficiency anemia MCV was very low(62.9±13.7fL), while RDW was very high(19.3±4.8) showing much lower MCV and much higher RDW in severe IDA compared with in mild IDA. To differentiate iron deficiency anemias form other anemias, a discriminant function was developed from some blood cell parameters like MCV, MCH, MCHC, RDW and platelets(D.F.=0.26 -0.012MCV -0.130MCH+ 0.073MCHC +0.052RDW +0.003PLT).

식물체로부터 추출한 물질이 상추 종자의 발아 및 생장에 미치는 영향

박건남,이민경,황선주,김학윤,이인중,신동현,김길웅 경북대학교 농업과학기술연구소 1999 慶北大農學誌 Vol.17 No.-

This study was conducted to detect the allelopathic effect of water and ethanol extracts from 4 plant species (Lactuca sativa L., Ambrosia elatior L., Oenothenra odorata Jasp., Ginkgo biloba L.) on germination and growth of lettuce seeds. A little bit higher inhibitory effect was obtained in ethanol extracts rather than water extracts. Allelopathic effects varied in the source of extracts and concentrations of 4 plant species and the highest allelopathic effect appeared in 10% solution, regardless of plant species.