호흡명상이 신경증적 고등학생의 분노와 집착에 미치는 영향

천성문,김경순,김정남 濟州大學校 職業能力開發院 2006 學生生活硏究 Vol.27 No.-

The present study developed a breathing meditation program for neurotic high school students and examined the effects of the program on neurotic high school students' anger and attachment. The main results of this study are as follows. First, the breathing meditation program had positive effects in easing the anger of highschool students with a neurotic tendency. Second, the breathing meditation program was found to be effective in relieving the attachment of high school students with a neurotic tendency. In addition, the present study examined through qualitative analysis which of the contents of breathing meditation work positively or dysfunctionally. The results of analysis on what experiences of breathing meditation relieve neurotic symptoms, anger and attachment are as follows. First, in the early stage of breathing meditation (session 1-3), the subjects were sensitive to the rise and wane of physical feelings. Second, during breathing meditation, the subjects recognized latent emotions deeper and longer and were highly sensitive to negative emotions (sorrow, pains, fear, attachment, etc.) and positive emotions (peace, purification, happiness, generosity, thankfulness, the feeling of being healed, etc.). Third, from the cognitive aspect, the subjects came to have an observer's view to look at problems from a distance and, as a result, they could understand and contemplate(improved concentration, breaking away from fear of death, separation of the body and mind from myself, disappearance of attachment to and anger over an object, off.) and some of them had transcendental experiences (seeing light, feeling of purification, dreamy experience, etc.). Fourth, as the subjects had personal training of meditation tasks in their everyday life, positive behavioral changes (confidence, determinedness, power of execution, generosity and brightness, smiling, etc.) were observed. Implications of this study based on its results as presented above are as follows. First, this study organized groups considering the psychological characteristics of highschool students with a neurotic tendency by supplementing the limitation of previous research. Second, this study developed a program by revising and supplementing therapeutic methods in accordance with the subjects' level and demand, considering that the subjects were high school students with neurotic tendency. Previous researches utilized a part or the whole of existing systematized meditation methods In their meditation programs. Such methods, however, were for adults, patients or religious trainees, they were not applicable to the adolescent subjects of this study, Thus, a new program was developed in accordance with the psychological characteristics and level of neurotic high school students. Third, in order to investigate the continuancy of effects after completing the experiment, this study carried out not only a post test but also a follow-up test. The long-term management and maintenance of remedial effects is an issue spotlighted in recent psychology (Kim Gye-hyeon, 2000). Thus the result of the follow-up test may provide data on the effects of experiments and researches on adolescents. Fourth, different from existing meditation programs, this study developed a program integrating physical, emotional, cognitive and behavioral factors. In addition, physical relaxation and cognitive approach, which are therapeutic factors proved to be effective in previous research, were also integrated into the program in order to bring forth changes in behavior and attitude through training and practice in everyday life. Fifth, considering that there have been few domestic researches on meditation related to the treatment of anger and attachment, this study provided a starting point of a therapeutic approach to meditation for the treatment of anger and attachment. What is more, a self-healing method was suggested, with which individuals can deal with anger and attachment through meditation.

알코올 사용 장애 환자에서 알코올 사용의 심각도에 따른 불안 및 우울 증상과의 연관성

천은진,이준엽,구본훈,문보영,정진영,정성훈 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:The purpose of this study was to examine the relationships of anxiety& depressive symptoms according to the severity of alcohol use in patients with alcohol use disorder. Methods:A total of 85 patients with alcohol use disorders were enrolled in this study. The severity of alcohol use was measured by the Korean version of alcohol use disorders identification test(AUDIT-K)& National Alcohol Screening test(NAST). Anxiety and depressive symptoms were measured by using the Beck Anxiety Inventory(BAI) and the Beck Depression Inventory(BDI), respectively. Pearson’s correlation test was applied to correlate among the severity of alcohol use, anxiety and depressive symptoms. Results:The mean scores of AUDIT-K, NAST, BAI and BDI were 22.22(±8.28), 6.24(±3.25), 18.64(±13.08), and 22.05(±10.13), respectively. Pearson’s correlation test showed that between the score of AUDIT-K and NAST, BAI or BDI, there were positively significant correlations(r=.534, p<.01 r=.231, p<.05 r=.334, p<.01), respectively. And in cases of≥26 score of AUDIT-K, there were much more positive correlations with BAI(r=.425, p<.05). Conclusion:The results of this study demonstrated that patients with alcohol use disorders have high co-morbid anxiety and depressive disorders. Overall, the greater severity of alcohol use may be associated with more anxiety and depressive symptoms. However, it is suggested that in the patients with severe alcohol use, correlation appeared to be positive only for anxiety symptoms.

교맥 에탄올 추출물의 멜라닌생성 억제효과

김대성,노성택,이장천,임규상,신미란,우원홍,문연자 한국전통의학연구소 2006 한국전통의학지 Vol.15 No.1

The aim of this study was to investigate the effect of ethanol extract of Fagopyrum escuentum(FE) on the melanogenesis. To determine whether ethanol extract of FE suppress melanin synthesis in cellular level, B16F10 melanoma cells were cultured in the presence of different concentrations of FE ethanol extract. In the present study, the author examined the effects of FE ethanol extract on cell proliferation, melanin contents, tyrosinase activity. Cell proliferation was slightly increased by treatment with ethanol extract of FE (25-200 ㎍/ml). The ethanol extract of FE effectively suppressed melanin contents at a dose of 100 ㎍/ml. It was observed that the color of cell pellets was totally whitened compared with the control. The ethanol extract of FE inhibited tyrosinase activity, regulate melanin biosynthesis as the key enzyme in melanogenesis. These results suggest that the ethanol extract of FE exerts its depigmenting effects through the suppression of tyrosinase activity. And it may be a potent depigmetation agent in hyperpigmentation condition.

진행성간문부담도암환자에서 경피경간 담도경하 광역동치료 및 담도배액술과 담도배액술사이의 생존비교

천영국 ( Cheon Yeong Gug ),김현정 ( Kim Hyeon Jeong ),김봉룡 ( Kim Bong Lyong ),차상우 ( Cha Sang U ),문종호 ( Mun Jong Ho ),조영덕 ( Jo Yeong Deog ),김연수 ( Kim Yeon Su ),이준성 ( Lee Jun Seong ),이문성 ( Lee Mun Seong ),심찬섭 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-

<목적> 진행성 간문부 담도암 환자에서 시행되고 있는 담도 배액술의 생존연장에 대한 결과는 아직까지는 만족스럽지 못하다. 최근 이런 환자에서 광역동치료를 시행하여 삶의 질 향상 및 생존율을 일부 높였다는 보고가 있다. 그러나 담도배액술군과 비교하여 발표한 광역동치료에 대한 결과가 없는 실정으로서 이에 본 연자들은 경피경간 담도배액술 및 담도경하 광역동 치료를 시행하고 그 결과를 내시경적 담도배액술만 시행한 경우와 후향적으로 비교하여 광역동 치료 효과를

역행성 내시경적 담도조영술상 정상소견을 보인 담관결석 고위험군 환자에서의 관강내 세경초음파검사소견

문종호 ( Mun Jong Ho ),차상우 ( Cha Sang U ),천영국 ( Cheon Yeong Gug ),김영석 ( Kim Yeong Seog ),조영덕 ( Jo Yeong Deog ),김연수 ( Kim Yeon Su ),이준성 ( Lee Jun Seong ),이문성 ( Lee Mun Seong ),심찬섭 ( Sim Chan Seob ),김부성 ( 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-

<목적> 관강내 세경초음파검사(intraductal US, IDUS)는 ERCP 시행 중에 고해상도의 담관 영상을 얻을 수 있으며 비교적 크기가 작은 담관 결석의 진단에도 용이하다. 임상 소견상 담관결석이 의심되는 경우 확진 및 치료를 위해 ERCP가 가장 중요한 검사로 되어 있으나 미세 담석은 진단이 안 되는 경우도 있어 확진을 위해 유두괄약근 절개술을 비롯한 불필요한 치료내시경술이 시행되어 질 수 있다. 이에 연자 등은 임상적으로 담관결석의 동반이

Effects on Skin Irritation and Turnover Rate by the Control of Skin Permeability of Alpha-hydroxyacids

( Cheon-koo Lee ),( Seong-don Hong ),( Mun-eok Park ),( Sun-gyoo Park ),( Seong-hoon Jeong ),( Seh-hoon Kang ) 대한화장품학회 1996 대한화장품학회지 Vol.22 No.2

The effect of a novel delivery system, water in oil emulsion containing chitosan hydrogel as a inner phase (W/O-C) was evaluated, and the relationships between the skin permeation, the skin primary irritation and the skin turnover rate of AHAs were discussed. We selected glycolic acid (GA), lactic acid (LA), malic acid (MA), and tartaric acid (TA) as model AHAs. The steady state fluxes of 4 AHAs across the excised hairless mouse skin increased as the molecular weights of the AHAs decreased (GA>LA>MA>TA). The skin turnover times were shortened in all AHAs, compared with control. The skin permeation and the skin primary irritation of the LA decreased and the skin turnover time increased, as the pH increased. The maximum therapeutic index was obtained with pH 3.8, 0.5 M LA. It was suggested that the skin permeability of LA might be a main factor for prediction of the skin irritation and the skin turnover time. On the other hand, the W/O-C containing pH 3.8, 0.5 M LA indicated a good sustained release property of LA, compared with water in oil emulsion without chitosan hydrogel (W/O) or oil in water emulsion (O/W). The skin permeability and the skin irritation of AHAs from the W/O-C decreased, compared with W/O or O/W, however the skin turnover time showed almost the same value as W/O or O/W. In conclusion, we suggest that the control of the skin permeation of AHAs would be an important tool for reducing the skin irritation and for maintaining the positive effect of AHAs, and the W/O-C system could be a potential candidate for future cosmetological application of AHAs.

토착한지의 특성 : 외발 초지법 분류를 중심으로 Classification of Oebal (single frame) Papermaking Methods

전철,김성주,진영문 한국목재공학회 1999 목재공학 Vol.27 No.1

This study was carried out to classify the Hanjis into three groups that were indigenous Hanji, traditional Hanji, and improved Hanji handmade by paper making method according to the physical properties of each paper sheet such as tensile, bursting and tearing strength, folding endurance and fiber orientation in each layer. The results obtained were summarized as follows: 1. The multi-layered Hanjis made by $quot;Oebal$quot; Hanji making method in different direction of fiber orientation have good properties in tearing resistance. 2. The multi-layered Hanji in different direction of fiber orientation has good properties in the tearing resistance, but the burst index and the breaking length results were lower than the single layered Hanjis. 3. The different fiber orientation and multi-layered method didn't increase the three indexes(burst index, tear index, breaking length). Only, the different direction of fiber orientation decreased the difference of width and length strength (tensile, tear) of the Hanji. 4. $quot;Dochim$quot;(Korean finishing touch process for indigenous Hanji by falling round sticks) greatly increase folding endurance(double folds, not logo) and good effect to tensile strength and burst strength. 5. The today's Oebal Hanji were the maximum of 2 layers and the indigenous Oebal Hanji were 16 layers the maximum. In addition, average of the indigenous Oebal Hanji was 4 layers(all 4-layer Hanji were the different fiber orientation of each layer). 6. The indigenous Hanji(multi-layered, and different fiber orientation) was good condition with $quot;Dochim$quot;. Dochim increased tensile strength and burst strength of the indigenous Hanji. So the three-strength indexes were similar level($quot;--$quot;). 7. When the number of layer which were same fiber orientation increase, the increased Hanji became similar strength pattern($quot;V$quot;, breaking length and burst index was higher than tear index) with $quot;Ssangbal$quot; Hanji. 8. The single layered papers that made by $quot;Oebal$quot; Hanji making method were similar strength pattern with Ssangbal Hanji. 9. There was no way to find the width and length direction of multi-layered Hanji by comparison between the difference of tensile strength and the difference of tearing resistance. 10. The compared pattern of tensile strength and tearing resistance of indigenous Oebal Hanji was different from today's Oebal Hanji. Especially, the tearing resistance of all indigenous Oebal Hanji(16 samples) was stronger on width of tearing resistance. And in the half of indigenous Oebal Hanji samples, the width of tensile strength and tearing resistance was stronger than length strength (Indigenous Oebal: '$lt;생략$gt;' 50%, '∪' 50% ↔ Today's Oebal: '$lt;생략$gt;' 12%, '∪' 6%, '$lt;생략$gt;' '17%, '∩' 65%). In 65% today's Oebal, the length direction of tensile strength and tearing resistance was stronger than the width direction.

Comparative profiling of breast cancer tissue membrane proteome by use of SDS-PAGE based cICAT method

Seong-Jun Park,Joohee Mun,Won Suk Yang,Mohammad Humayun Kabir,Jeonghun Yeom,Jihye Shin,Hee-Sung Ahn,Shinyeong Joo,Yu Mi Kwon,Mijeong Kim,Dong Huey Cheon,Su-Min Lee,Yae Eun Park,Kyeong Yeon Kim,Ji Eun 한국구조생물학회 2015 Biodesign Vol.3 No.1

Breast cancer is the most common cancer among women worldwide. There is an emerging interest in protein expression profiling with the aim of identifying novel diagnostic markers and therapeutic targets in breast cancer. We analyzed breast cancer tissues by using the cICAT (cleavable isotope-coded affinity tag) labeling approach and tandem mass spectrometry. Breast cancer and matched normal tissues were fractionated by ultracentrifugation to enrich membrane proteins, and cICAT labeled proteins were separated by SDS-PAGE. A total of 364 proteins were identified and quantified. Among the proteins that showed >1.5 fold difference between normal and cancer (36.6%), five (RPN1, ERp29, Trop2, PrP and PIGR) were selected for confirmation. Western blot on 10 pairs of normal and cancer tissues revealed that the expression of RPN1 and ERp29 were increased in breast cancer tissue, while Trop2, PrP and PIGR were decreased. Those Western blot results were highly consistent with cICAT results. Higher level of RPN1 and ERp29 and lower level of Trop2 in breast cancer cell lines compared to normal breast cell lines were observed. The result supports reliability of our SDS-PAGE based ICAT method in quantifying cancer tissue proteome.

Dedicated Multiprocesser System for Document Recognition

Mun Hyoung Cho,Jong Soong Lim,J. G. Choi,Jae Gyun Cheong,Hee Ho Roh,Seong Hee Cheon,Shin Wook Kang 대한전자공학회 1991 International Conference on Electronics, Informati Vol.1 No.1

Reduction of Skin Irritation by Control of Skin Permeation of Methyl Paraben

( Seong-hoon Jeong ),( Mun-eok Park ),( She-hoon Kang ),( Cheon-koo Lee ) 대한화장품학회 1997 대한화장품학회지 Vol.23 No.3

The skin permearion study has two meanings in cosmetics. One is how to promore the skin permearion of active materials (e.g. skin whitening agents, anti-ageing agents) for improving their bioavailabilities and the other is how to decrease it of irritants (e.g. preservatives, perfumes, sunscreen agents) for reducing their skin side effects. In this study, we selected methyl paraben (MP), one of the preservatives, as a model irritant and tried to reduce the skin irritation by the decrease of skin permearion. Furthermore, the relationship between skin permeation and skin primary irritation was discussed. For in vitro skin permeation experiments, Franz type diffusion cells (effective diffusional area: 1.766 cm2) and the excised skin of female hairless mouse from 8 weeks old were used. The donor compartment was charged with oil only or O/W emulsion containing 0.3% MP. We selected 19 oils, including esters, triglycerides, plant oils, hydrocarbons, and alcohols, which are broadly used in cosmetics. We determined the oil/water partition coefficient of MP ar 32+C. The skin primary irritation was evaluated with female guinea pig (8-10 weeks, 350-400 g). The skin permeability of MP from the oils showed following order: ester oils > triglycerides > plant oils > hydrocarbons > alcohols We considered that this result was based on the different effect of each oil on the barrier function of stratum comeum. In O/W emulsion containing each oil, the skin permeability of MP decreased as the oil/water partition coefficient of MP increased. The skin primary irritation increased as the skin permeabiliry of MP increased. In conclusion, we suggest that the skin irritation could be reduced by the decrease of skin permeability of MP,which may be obtained by the good selection of oils in cosmetic preparations.