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      • KCI등재

        A Ultra-Low Specific On-Resistance and Extended Gate SJ LDMOS Structure

        Lijuan Wu,Jiaqi Chen,Hang Yang,QiLin Ding,Xing Chen,Shaolian Su 한국전기전자재료학회 2021 Transactions on Electrical and Electronic Material Vol.22 No.3

        A new structure of extended gate (EG) SJ LDMOS is proposed in this paper to overcome the substrate assisted depletion (SAD) eff ect in the structure of Super-Junction lateral double diff used metal oxide semiconductor (SJ LDMOS). Different from other surface SJ structures, the SJ layer of the structure is located in the body of the drift region. Gate oxide and silicon layer form the EG Structure-Oxide-Semiconductor structure that is similar to Metal–Insulator–Semiconductor capacitor. The the N-drift of the EG structure can obtain the charge compensation to overcome the SAD eff ect, and a nearly rectangular electric field is achieved. In the on-state, the EG structure has two conductive channels and the accumulation layer is formed on the drift region. By accumulating high concentration electrons in the channels, the specifi con-resistance ( R ON,sp ) is greatly reduced. When the drift length is 24 μm, 431.4 V breakdown voltage ( V B ) and 9.8 mΩ cm 2 R ON,sp are achieved, and the fi gure of merit is 18.9 MW cm −2 .

      • KCI등재

        재무부정의 동기: 중국 루이씽커피의 사례를 중심으로

        오려견 ( Lijuan Wu ),황위동 ( Weidong Huang ),김산월 ( Shanyue Jin ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.6

        루이씽커피는 중국의 신흥 커피 브랜드다. 루이씽커피는 온라인과 오프라인에서 운영되는 저렴한 커피 브랜드를 만들었으며 2019년에 성공적으로 나스닥에 상장하였다. 하지만 2020년에 루이씽커피의 재무부정이 폭로되었고 얼마 지나지 않아서 상장폐지 되었다. 따라서 본 연구는 루이씽커피의 재무부정이 왜 일어났는지 그 이유에 대해 설명하고 해결책을 제시하고자 한다. 본 연구는 사례연구 방법과 재무분석 방법을 적용하여 루이씽커피의 재무부정의 원인을 탐욕, 기회, 수요, 공개요인의 관점에서 해석하였다. 본 연구는 루이씽커피의 사례를 통해 기업들이 지배구조를 발전시키고 내부 통제를 강화해야 한다는 것을 제시하고 있다. Luckin Coffee is an emerging coffee band in China. It created an inexpensive coffee brand operating online and offline and soon successfully got listed on NASDAQ in 2019. However, Luckin Coffee’s financial fraud was revealed in 2020 and it was delisted shortly after. Therefore, this study aims to explain the reason why Luckin Coffee’s financial corruption occurred and suggest the solutions. The study applied the case study method and the financial analysis method to explain the causes of Luckin Coffee’s financial fraud in terms of greed, opportunity, demand, and exposure factors. This study suggests that companies should develop their governance structure and strengthen internal control through case of Luckin Coffee.

      • KCI등재

        Prevalence of Depression in Ankylosing Spondylitis: A Systematic Review and Meta-Analysis

        Lijuan Zhang,Yaping Wu,Shiguang Liu,Weiyi Zhu 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.8

        The aim of this study was to provide a summary estimate of depression prevalence among people with ankylosing spondylitis (AS) in comparison to those without AS. A systematic literature search was conducted using PubMed, Embase, PsycINFO, Web of Science, the Cochrane database library, China National Knowledge Infrastructure, and Wanfang Database from their inception to December 2016. The results showed that thirty-one eligible studies involving 8,106 patients were analyzed. Fifteen methods of defining depression were reported. The overall pooled prevalence of depression was 35% (95% CI, 28–43%), with high between-study heterogeneity (I2=98.8%, p<0.001). The relative risk of depression among people with AS was 1.76 (95% CI: 1.21–2.55, eight studies, n=3,006) compared with people without AS. The depression score [standardized mean difference (SMD)=0.43, 95% CI: 0.19–0.67, seven studies, n=549] was higher in AS patients than in controls. The main influence on depression prevalence was the sample size and country of origin. In conclusion, one-third of people with AS experience symptoms of depression. Depression was more prevalent in AS patients than in controls. Further research is needed to identify effective strategies for preventing and treating depression among AS patients.

      • KCI등재

        Bond Behaviors between Ribbed BFRP Bars and Ecological High Ductility Cementitious Composites

        Lijuan Chai,Liping Guo,Bo Chen,Jiandong Wu 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.11

        Direct pull-out method was conducted to explore the bond stress-slip response of ribbed basalt fiber reinforced polymer (BFRP) bars embedded in ecological high ductility cementitious composites (Eco-HDCCs). The effects of the embedment length and cover thickness on the bond properties between Eco-HDCCs and the bars were described. Results indicate that the failure characteristics of the specimens depend on the embedment length and cover thickness of the BFRP bars. As the embedment lengths of the bars increase, the ultimate bond stress decreases while the ultimate slip increases. Besides, both the ultimate bond stress and ultimate slip show an increasing trend if the specimen has a cover thickness of less than 45 mm, while the increasing trend is slower if the specimen has a cover thickness of more than 45 mm. In addition, the strain of the specimen surface depends on the cover thickness, and the strain increases when the cover thickness is in a range of 15 mm − 35 mm. Moreover, certain embedment lengths and cover thicknesses of the BFRP bars are recommended in the structural design of bridge deck link slabs. The bond stress-slip relationship models of the BFRP bars in Eco-HDCCs are proposed based on the test results.

      • KCI등재

        Identifi cation of key leaf color-associated genes in Gleditsia sinensis using bioinformatics

        Chong Wu,Xuemei Yang,Lijuan Feng,Fei Wang,Haixia Tang,Yanlei Yin 한국원예학회 2019 Horticulture, Environment, and Biotechnology Vol.60 No.5

        This study aimed to explore leaf-color associated genes in Gleditsia sinensis ( G. sinensis ) using bioinformatics methods. Green, purple, and yellow leaves were collected from G. sinensis in Shandong Institute of Pomology. Total RNA was collectedfrom leaves and subjected to transcriptome sequencing. Diff erentially expressed genes (DEGs) were identifi ed amongthe diff erent colored leaves using RSEM method followed by functional enrichment analysis. Finally, qRT-PCR analysis wasused to assess the expression of several pigment-related genes enriched in signifi cant GO or KEGG terms. A total of 10,953,14,961, and 8916 DEGs were identifi ed between green vs. purple leaves, green vs. yellow leaves, and purple vs. yellow leaves,respectively. Among the green vs. purple leaves, DEGs were signifi cantly enriched in terms of iron ion binding, tetrapyrrolebinding, (e.g., CYP26A1 , CYP97A3 , and CYP86A1 ), and starch and sucrose metabolism (e.g., TPS and VTC2 ). DEGsfor green/purple vs. yellow groups were markedly enriched in circadian rhythm-plant KEGG pathway, including ELF3 andCHS . Compared with their expression in green leaves, CYP26A1 , CYP97A3 , CYP86A1 , TPS and VTC2 were signifi cantlydownregulated in purple leaves, while downregulation of ELF3 and upregulation of CHS was detected in yellow leaves. CYPs (e.g., CYP26A1 and CYP97A3 ) might play critical roles in the determination of leaf color in G. sinensis via iron ionand tetrapyrrole binding. In addition, genes related to starch and sucrose metabolism (e.g., TPS and VTC2 ), and circadianrhythms (e.g., ELF3 and CHS ) might also be involved in controlling leaf color.

      • SCOPUSKCI등재

        Surface Modification of Colloidal Silica Nanoparticles: Controlling the size and Grafting Process

        He, Wentao,Wu, Danhua,Li, Juan,Zhang, Kai,Xiang, Yushu,Long, Lijuan,Qin, Shuhao,Yu, Jie,Zhang, Qin Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.9

        Surface modification of colloidal silica nanoparticles without disrupting the electric double layer of nanoparticles is a major challenge. In the work, silane was employed to modify colloidal silica nanoparticles without inducing bridge flocculation obviously. The effect of pH value of the silica sol, the amount of silane in feed, and reaction temperature on the graft amount and the final size of modified particles was investigated. The increased weight loss by TG and the appearance of $T_2$ and $T_3$ except for $Q_2$ and $Q_3$ signals by CP/MAS $^{29}Si$ NMR of the modified samples verified the successful grafting of silane. The graft amount reached 0.57 mmol/g, which was slightly lower than theory value, and the particle size remained nearly the same as unmodified particles for acidic silica sol at the optimum condition. For alkaline silica sol after modification, aggregates composed of several nanoparticles connected together with silane moleculars as the bridge appeared.

      • SCIESCOPUSKCI등재

        Role of Interleukin-4 (IL-4) in Respiratory Infection and Allergy Caused by Early-Life Chlamydia Infection

        ( Shujun Li ),( Lijuan Wang ),( Yulong Zhang ),( Long Ma ),( Jing Zhang ),( Jianbing Zu ),( Xuecheng Wu ) 한국미생물 · 생명공학회 2021 Journal of microbiology and biotechnology Vol.31 No.8

        Chlamydia pneumoniae is a type of pathogenic gram-negative bacteria that causes various respiratory tract infections including asthma. Chlamydia species infect humans and cause respiratory infection by rupturing the lining of the respiratory which includes the throat, lungs and windpipe. Meanwhile, the function of interleukin-4 (IL-4) in Ch. pneumoniae respiratory infection and its association with the development of airway hyperresponsiveness (AHR) in adulthood and causing allergic airway disease (AAD) are not understood properly. We therefore investigated the role of IL-4 in respiratory infection and allergy caused by early life Chlamydia infection. In this study, Ch. pneumonia strain was propagated and cultured in HEp-2 cells according to standard protocol and infant C57BL/6 mice around 3-4 weeks old were infected to study the role of IL-4 in respiratory infection and allergy caused by early life Chlamydia infection. We observed that IL-4 is linked with Chlamydia respiratory infection and its absence lowers respiratory infection. IL-4R α2 is also responsible for controlling the IL-4 signaling pathway and averts the progression of infection and inflammation. Furthermore, the IL-4 signaling pathway also influences infection-induced AHR and aids in increasing AAD severity. STAT6 also promotes respiratory infection caused by Ch. pneumoniae and further enhanced its downstream process. Our study concluded that IL-4 is a potential target for preventing infection-induced AHR and severe asthma.

      • KCI등재

        Surface Modification of Colloidal Silica Nanoparticles: Controlling the size and Grafting Process

        Wentao He,Danhua Wu,Juan Li,Kai Zhang,Yushu Xiang,Lijuan Long,Shuhao Qin,Jie Yu,Qin Zhang 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.9

        Surface modification of colloidal silica nanoparticles without disrupting the electric double layer of nanoparticles is a major challenge. In the work, silane was employed to modify colloidal silica nanoparticles without inducing bridge flocculation obviously. The effect of pH value of the silica sol, the amount of silane in feed, and reaction temperature on the graft amount and the final size of modified particles was investigated. The increased weight loss by TG and the appearance of T2 and T3 except for Q2 and Q3 signals by CP/MAS 29Si NMR of the modified samples verified the successful grafting of silane. The graft amount reached 0.57 mmol/ g, which was slightly lower than theory value, and the particle size remained nearly the same as unmodified particles for acidic silica sol at the optimum condition. For alkaline silica sol after modification, aggregates composed of several nanoparticles connected together with silane moleculars as the bridge appeared.

      • SCIESCOPUSKCI등재

        Effects of Lactobacillus curvatus and Leuconostoc mesenteroides on Suan Cai Fermentation in Northeast China<sup>s</sup>

        ( Hongyan Yang ),( Hao Wu ),( Lijuan Gao ),( Hongbai Jia ),( Yuan Zhang ),( Zongjun Cui ),( Yuhua Li ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.12

        To investigate the effects of Lactobacillus curvatus and Leuconostoc mesenteroides on suan cai (pickled Chinese cabbage) fermentation, L. curvatus and/or Ln. mesenteroides were inoculated into suan cai. Physicochemical indexes were measured, and the microbial dynamics during the fermentation were analyzed by Illumina MiSeq sequencing and quantitative polymerase chain reaction (qPCR). The results showed that inoculation with lactic acid bacteria (LAB) lowered the pH of the fermentation system more rapidly. The decrease in water-soluble carbohydrates in the inoculated treatments occurred more rapidly than in the control. The LAB counts in the control were lower than in other inoculated treatments during the first 12 days of fermentation. According to the Illumina MiSeq sequencing analyses, Firmicutes, Proteobacteria, Bacteroidetes, Actinobacteria, Cyanobacteria, Fusobacteria, and Verrucomicrobia were present in the fermentations, along with other unclassified bacteria. Generally, Firmicutes was predominant during the fermentation in all treatments. At the genus level, 16 genera were detected. The relative abundance of Lactobacillus in all inoculated treatments was higher than in the control. The relative abundance of Lactobacillus in the treatments containing L. curvatus was higher than in the Ln. mesenteroides-only treatment. The relative abundance of Leuconostoc in the Ln. mesenteroides-containing treatments increased continuously throughout the fermentation. Leuconostoc was highest in the Ln. mesenteroides-only treatment. According to the qPCR results, L. curvatus and/or Ln. mesenteroides inoculations could effectively inhabit the fermentation system. L. curvatus dominated the fermentation in the inoculated treatments.

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