체중감량이 유도선수의 Renin, 면역기능 및 유·무산소 운동능력에 미치는 영향

권영우,전승훈,김진해,민경선,민진아 한국스포츠리서치 2001 한국 스포츠 리서치 Vol.12 No.4

The purpose of this study was to investigate the effect of short terms weight reduction period on body composition and body fluid. Seven Judo athletes (21±1.21 yrs) were matched and randomly placed. Body weight reduction period consists of 7 day. Each groups reduced body weight by 3%(2th day from pre weight reduction), 5%(4th day from pre weight reduction, 7%(7th day) and investigated the recovery period on 3 hour after breakfast, lunch, and 1day, 2day after 7% body reduction. Weight reduction reduced weight during weight reduction period then returned to baseline during recovery(p<.05) and decreased LBM, electrolyte, and immune function and then increased in recovery period to baseline. In conclusion, weight reduction of Judo athletes caused the change biological variable and performance and STWR may detrimental effects body' homeostasis.

폐경기 여성에서 1년간 호르몬 대치 요법이 혈청 지질에 미치는 영향

이해혁,남계현,김승형,이임순,이권해,최승도 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Cardiovascular disease is one of the most common cause of death in postmenopausal women. After the onset of menopause, the risk of cardiovascular disease is increased. Several risk factors of cardiovascular disease are well known to us. Among the risk factors, the changes of lipid profiles are roles for cardiovascular disease. Estrogen appears to protect the development of cardiovascular disease, by several mechanism. Especially the protective effect is believed to be mediated by the changes of lipid profiles. Decreased high-density lipoprotein (HDL)-cholesterol and increased low density lipoprotein (LDL)-cholesterol are important factors for development of cardiovascular disease. The purpose of this study was to evaluate the effect of hormone replacement therapy on the lipid profiles to include total cholesterol (TC), high density lipoprotein(HDL)-cholesterol, low density lipoprotein(LDL)-cholesterol, and triglycerides. We measured lipid profiles in 31 postmenopausal women and gave each conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 5mg, day 1-12) for 12months. The levels of serum TC, LDL-cholesterol, and triglycerides were decreased significantly (p<0.05) and HDL-cholesterol was increased significantly (p<0.05) after 12months of hormone replacement therapy. These data suggest that hormone replacement therapy appears to protect agianst the development of cardiovascular disease by the changes of lipid profiles.

다공질 TiNi 형상기억합금의 고온자전합성에 관한 연구 : A Study on the Self-propagating High-tempaerature Synthesis of Porous TiNi shape Memory Alloy

이승해,김지순,권영순 울산대학교 1999 공학연구논문집 Vol.30 No.2

고온자전합성법을 이용하여 다공질 TiNi 금속간화합물을 제조하였다. 합성반응에 미치는 원료분말의 특성과 성형체 밀도, 점화온도 등의 영향을 생성물의 미세조직 관찰과 상분석, 기공도 및 기공구조 분석을 통하여 조사하였다. 다양한 원료분말을 사용하여 이들의 조합을 달리하여 준비한 혼합분말에 대한 반응 결과, 반응을 일으키는 최소점화온도는 280-500℃의 넓은 온도 범위로 확인되었으며, Hunter법으로 제조된 Ti 원료분말과 카르보닐 Ni 원료분말을 혼합한 경우에 가장 안정된 반응거동과 양호한 기공구조를 나타내었다. 제조된 반응생성물의 상분석 결과 단상의 TiNi와 제2상으로Ti₂Ni, TiNI₃등이 관찰되었으며, 제2상은 점화온도가 높아짐에 따라 감소하였다. 점화온도의 증가에 따라 기공의 크기도 감소하였으며 그 분포가 균일하여짐을 확인하였다. Porous TiNi intermetallic compound was produced by SHS(Self-propagating High-temperature Synthesis). Effects of starting powder characteristics, green density and ignition temperature on synthesis reaction were investigated through microstructural observation, phase analysis, porosity and pore structure of reacted specimens. Minimum ignition temperature for a propagation of thermal wave front ranged from 280 to 500℃ which varied according to starting powder characteristics. Mixtures of Ti produced by Hunter process and carbonyl Ni powders showed a stable reaction behavior and a good pore structure. From the results of XRD phase analysis TiNi was confirmed as a major phase. Additionally, Ti₂Ni and TiNi₃phases were also detected as second phases. The amount of teh second phases decreased with increasing ignition temperature which resulted also in a decrease of pore size and uniform distribution of pores.

일부 흡연 대학생의 지각된 스트레스와 흡연실태에 대한 상관관계 연구

강초록,권시내,권혜림,박수경,송인혜,오해인,이미지,한승아,황선아,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

In spite of the seriousness of smoking harm has been developed these days. the increase of national smoking rate and that the people in the twenties are especially leading the rise of national smoking rate is an important issue of national health. Smoking of the university students can occur health problem and cause loss of manpower and expenses in their social activity period. So then the actual state for prevention of smoking and development of a program to prohibit smoking has to be seized urgently and starting with the study of the realities of university students, the effort to find a related fluent of smoking has to be studied. Related to this, the purpose of this study is to seize the general characteristics of smoking university students and to find out the relationship between perceived stress and smoking status among smoking university students. In addition, by collating the relationship between perceived stress and smoking status among smoking university students we have the purpose to furnish the basal data of stress care, the best way to cope with stress through group training and the plan for nursing implementation to decrease the smoking rate. For this study, a survey was conducted for 204 smoking university students of 13 universities in Seoul from 9th of May to 16th of May, 2003. The collected data was analyzed by t-test, Pearson Correlation and ANOVA in the statistical packages SPSS/PC. Major findings of this study are as follows; 1. Of the 204 respondents 85.4% of them were male and 14.6% of them were female. The average age of the sample was 23.19 years old and 41.8% of them were in senior, 21.4% in junior, 16.9% in sophomore, 19.9% in freshman grade. The major motivation to start smoking was 'because of curiosity'(33.8%) and the first smoking experience was at 'senior high school' (41.9%) and at 'college' (41.9%). 2 The highest scored stress factor of smoking university students were stresses about school work. 3. 72.7% had experience to quit smoking at least one or more times. Most of the reason to keep on smoking was 'short will to quit'(51.0%) and the smoking place was usually at 'school' (41.4%). Most respondents for the number ofsmoking friends were '5 people and above' (73.2%). 4. There was a negative relationship between the general characteristics and the entire perceived stress, however, there was a positive relationship between the general characteristics and the perceived stress in 4 categories which is 'sex distinction', 'major of study', 'residence form' and' inmate'. 5. There was a negative relationship between the general characteristics and the entire smoking status, however, there was a positive relationship between the general characteristics and the smoking status in 2 categories which is 'presence of hobby' and 'number of smoking friends'. 6. There was a negative relationship between the perceived stress and the smoking status. Through this study we have seized the relationship between the general characteristics, perceived stress and the smoking status of smoking university students. There was a positive relationship between some of the general characteristics with the perceived stress and the smoking status of smoking university students. Also there was a negative relationship between the perceived stress and the smoking status.

수용성 Polymer-metal Complex의 형성과 중합 개시제로서의 활용성에 관한 연구(Ⅰ)

맹기석,송해영,권오승,황명천,황택성 충남대학교 공업교육연구소 1983 論文集 Vol.6 No.2(B)

The formation of Water-Soluble Poly(Methacrylic acid) (PMA) and poly (acrylamide) (PAAm)-Cu(II) complexes was achieved at various PH. The structures and the optimum conditions for the formation of complexes have been determined through UV, IR and viscosity measurements. In addition, it was found that they can be used as an initiator for vinyl type monomers. Formed polymer-metal complexes are the most stable at around PH=7 and therefore give rise to maximum absorbance in UV spectrum. As PH is increased the conformation of polymer-metal complexes has become more compact. This can be explained in terms of decreasing viscosity with increasing PH. It was also observed that the function as an initiator of the polymer-metal complexes is very active at around PH=7 and the complexes can polymerize vinyl type monomers up to 10% Conversion. These results can explain the fact that the stable complexes were formed at around PH=7 and the formed complexes can be used as good initiators.

장기투석을 받은 만성 신부전 환자에서 발생한 종양에 관한 고찰

황정화,이혜경,홍현숙,박재성,김대호,권귀향,최득린,황승덕,이희발 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

The authors tried to evaluate tumor occurrence in long-term dialysis patients with chronic renal failure. Among 359 patients, 20 patients (about 5.6%) were diagnosed with malignancy during long-term dialysis from the period of 1983 to 1995 at our nephrology department. The ultrasonographic and computed tomographic findings including the clinical features of 20 patients that were retrospectively reviewed. The mean age of the patients was 53 (37-75)years old and the ratio of male to female was 9:1. Among the 20 cases, 7 cases of hepatoma (35%) were developed. Among them, urinary tract tumors such as renal and bladder cancer were developed in 4 (20%) and 2 (10%) of the cases. Other malignant tumors were lymphoma, stomach cancer, uterine cervical cancer, cholangiocarcinoma, lung cancer, meningioma, and acoustic neuroma one case of each (each of 5.3%). The most common tumor in patients with chronic renal failure, who were receiving long-term dialysis, was hepatoma and the second most common tumor was cancer of the urinary tract such as kidney and bladder.

갱년기 여성의 호르몬 대치 요법에 대한 수용율

이임순,장진영,이정재,이순곤,이권해,이해혁,김승형 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Purpose: We have evaluated the compliance of hormone replacement therapy. Method: There are 185 climacteric women who are divided into three groups (Group I, Group II, Group III). Group I is given conjugated equine estrogen(CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate(MPA, 5mg, day 1-12). Group II is given conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 2.5mg, day 1-30), Group III is given only conjugated equine estrogen(CEE, 0.625mg, day 1-30). Results: 1) The compliance rate of hormone replacement therapy during three months is 77.9% including each Group I : 77.7%, Group Ⅱ : 76.1%, Group Ⅲ :80.4%. 2) The compliance rate of hormone replacement therapy during six months is 60.7% including each Group Ⅰ:52.9%, Group Ⅱ: 56.4%, Group Ⅲ: 79.5%. 3) The compliance rate of hormone replacement therapy during nine months is 49.7% including each Group Ⅰ: 45.5%, Group Ⅱ:41.7%, Group Ⅲ: 64.3%. 4) The compliance rate of hormone replacement therapy during a year is 44.4% including each Group Ⅰ: 40.2%, Group Ⅱ:35.3%, Group Ⅲ: 59.5%. Conclusion : It is vital that we maximize compliance if patients are to receive the full benefits from hormone replacement therapy. We think that physicians who prescribe hormone replacement therapy for climacteric women should enough explain the purpose, risks, and side effect of treatment for maximizing compliance of hormone replacement therapy.

HBV : Efficacy of Entecavir and Adefovir Combination Therapy in Patients with Multi-antiviraldrug resistant Hepatitis B Virus

( Seung Kak Shin ),( Young Kul Jung ),( Seung Jun Jang ),( Hae Lim Baek ),( Hyun Hwa Yoon ),( Soo Yong Park ),( Min Young Rim ),( Hyeonsu Park ),( In Ku Yo ),( Oh Sang Kwon ),( Yun Soo Kim ),( Duck Jo 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1

Background: Multi-antiviral drug resistance is a major problem in the treatment of patients with chronic hepatitis B (CHB). Tenofovir disoproxil fumarate (TDF) is recommended for ADV or entecavir (ETV). However, until recently TDF was not available in Korea. ADV and ETV combination therapy may be a viable alternative to TDF in patients with either ADV or ETV resistance. This study investigated the efficacy of ADV and ETV combination therapy in patients with multidrug resistance. Methods: Forty-one patients were enrolled and were administered ADV and ETV combination therapy for at least 12 months. Blood was drawn at baseline and at 12, 24, 36, 48, and 60 months after commencing treatment, and virological response was analyzed. Results: After ADV and ETV combination therapy, ALT normalization was 68%, 73%, 80% 90%, and 93% in 12wks, 24wks, 36wks, 48wks, and 60 wks, respectively. HBV DNA reduction was -1.5, -1.8, -1.9, -1.8, and -1.9 log10IU/mL in 12wks, 24wks, 36wks, 48wks, and 60 wks, respectively. 29 of HBeAg positive patients showed the following low HBeAg seroconversion rate: 3%, 7%, and 10% in 24wks, 48wks, and 60wks, respectively. In addition, virological response group showed lower initial HBV DNA level (P=0.014) and lower HBeAg positive rate (P=0.016) compared with non-virological response group. Conclusions: ADV and ETV combination therapy could be considered in selected chronic hepatitis B patients who have low initial HBV DNA level and HBeAg negative status.

Nasal airway clogging recurrent viral warts treated with oral cimetidine in a young male patient

( Seung Hwi Kwon ),( Jin Young Song ),( Geo Han ),( Hae Jun Song ),( Chil Hwan Oh ),( Jiehyun Jeon ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Cimetidine is a histamine2-receptor antagonist, frequently used as anti-ulcer agents. Cimetidine also possesses immunomodulatory effects when given in high dosage. Because of these features, it had been prescribed for the treatment of viral warts. A 32-year-old male patient visited our clinic with multiple protruding papules in nostril, external auditory canal, and sole with no other underlying disease. When he had noticed the lesions, he visited otolaryngology clinic and laryngoscopy exam revealed inner airway warty lesions. He had received laser treatment but warts came back only worsened. Histopathological findings showed acanthosis, papillomatosis and hyperkeratosis, consistent with viral warts. The patient was given cimetidine up to 1800mg/day and all the noticeable warts cleared after 4months. Cutaneous warts are the manifestation of human papillomavirus (HPV) infection. Cell-mediated immune response is critical in the involution of HPV infection. There are several treatment options including oral cimetidine. Oral cimetidine is painless and inexpensive option. It has an inhibitory effect on suppressor T-cell function when given in high dose (30-40 mg/kg per day). Use of cimetidine for viral warts has been reported in the literature, but still conflicting. Herein, we present a 32-year-old male patient with airway clogging multiple viral warts successfully treated with oral cimetidine for 4 months without recurrence or side effects.

A case of acquired smooth muscle hamartoma on hand

( Seung Hwi Kwon ),( Jung Woo Lee ),( Jiehyun Jeon ),( Chil Hwan Oh ),( Hae Jun Song ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Smooth muscle hamartomas are uncommon benign neoplasms that are characterized by increased density of smooth muscle bundles in the dermis. It is a skin colored or variably pigmented and even showing hypertrichosis patch or plaque. Although most cases were congenital, acquired lesions have been rarely reported. Histopathologically, lesions showed hyperkeratosis, acanthosis and papillomatosis. Numerous thick, long, well-defined bundles of smooth muscle are seen in the dermis at various angles of orientation. There is clinical and histological overlap with Becker nevus and pilar leiomyoma. Becker nevus is usually acquired dark brownish hairy macule with relatively thin bundles of smooth muscles and much more common in males and adolescence. Pilar leiomyoma is usually seen as protruding nodular lesions and forms smooth muscle bundles intermingled with collagen fiber. A 57-year-old female patient presented with 5 years history of asymptomatic hairless light brown irregular indurated follicular plaques limited on right dorsum of hand. Lesion was a child fist sized and margin was irregular. Histopathological findings exhibited mild epidermal acanthosis, focal basal pigmentation and haphazardly arranged numerous thick, well-defined smooth muscle bundles in the reticular dermis. Herein we report a case of smooth muscle hamartoma on hand with reviewing of literatures.