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민진아,박석,성기운,채창훈,김지연,노종철,우도영 한국운동영양학회 2012 Physical Activity and Nutrition (Phys Act Nutr) Vol.16 No.4
The aim of present study was to investigate the effect of exercise and/or L-arginine on Insulin growth factor-Ⅰ(IGF-Ⅰ) and lipid profile in high fat induced obese rat. For our experiment, male Sprague-Dawley rats (n = 32) at age 6 weeks were divided into four groups as follows: (1) High fat diet (HF), (2) HF with Exercise (EX), (3) HF with Arginine injection (ARG), (4) HF with EX + ARG (EX + ARG). The groups performed the training program for 12 weeks. After the program, blood was collected from left ventricle for analysis. As a result of analysis, IGF-Ⅰ was significantly increased in both EX + ARG and ARG (p < .05)while IGF binding protein (IGFBP) was not significantly different among the groups. Total cholesterol (TC) and LDL-C were significantly decreased in EX + ARG and EX (p < .05). In conclusion, this study suggests that combination of regular aerobic exercise and L-arginine consumption might prevent cardiovascular disease by increasing IGF-Ⅰ and decreasing TC and LDL-C.
민진수,박재석,김주상,신아영,이성순,고운영,박미선,이주선,천가영 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Background: Although overall incidence of tuberculosis (TB) has decreased in South Korea, it has still high mortality rate. TB mortality is one of the important indicators for TB control interventions. The purpose of this study was to identify risk factors for mortality during treatment of adult patients with pulmonary TB. Methods: A multicenter retrospective cohort study was performed at private-public mix hospitals across South Korea. Between 2015 and 2017, 3735 mortality cases of pulmonary TB were collected. All TB deaths were categorized based on cause (TB-related or non-TB-related death) and timing (early or late death). Drug-resistant TB was excluded. Results: The mean age was 74.3±13.0 years, and there were 2541 (68.0%) males. The median interval between anti-TB treatment and death was 26.0 days. There were 944 (25.3%) cases of TB-related death and 2545 (68.1%) cases of early death. Among 2791 cases of non-TB-related death, respiratory failure was the most common mode of death, followed by malignant neoplasm. In multivariate analysis, low body mass index, previously healthy individual, positive acid fast bacilli smear test result, and dyspnea were significant risk factors for both TB-related death and early death, and malignancy was a significant risk factor for both non-TB-related death and late death. Conclusion: High proportion of TB death was observed elderly patients. Majority of TB deaths were ascribed to non-TB-related causes. Early interventions identifying TB patients at high risk of death are necessary in order to reduce TB mortality.
Non-Surgical Management of Critically Compromised Airway Due to Dilatation of Interposed Colon
민진수,조영재 대한결핵및호흡기학회 2016 Tuberculosis and Respiratory Diseases Vol.79 No.2
We present a rare case of critically compromised airway secondary to a massively dilated sequestered colon conduit after several revision surgeries. A 71-year-old male patient had several operations after the diagnosis of gastric cancer. After initial treatment of pneumonia in the pulmonology department, he was transferred to the surgery department for feeding jejunostomy because of recurrent aspiration. However, he had respiratory failure requiring mechanical ventilation. The chest computed tomography (CT) scan showed pneumonic consolidation at both lower lungs and massive dilatation of the substernal interposed colon compressing the trachea. The dilated interposed colon was originated from the right colon, which was sequestered after the recent esophageal reconstruction with left colon interposition resulting blind pouch at both ends. It was treated with CT-guided pigtail catheter drainage via right supraclavicular route, which was left in place for 2 weeks, and then removed. The patient remained well clinically, and was discharged home.