서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

대학생의 술에 대한 기대가 음주행동에 미치는 영향

홍종필 연세대학교 대학원 1990 원우론집 Vol.- No.17

The present study investigated whether heavy and problem drinkers among college students expected significantly more reinforcement from alcohol than their light and normal drinking peers. It also examined whether the alcohol-related expectancies of college students varied as a function of their drinking patterns and compared expectancies with demographic / background variables for their predictive power of drinking behaviors. A questionnaire on the expected effects of alcohol was administered to 770 male college students, and optimal alcohol-related expectancy and demographic / background predictors of drinking behavior were selected and compared via stepwise multiple regression procedures. Results indicated that alcohol-related expectancies were different depending on drinking styles and that alcohol-related expectancies added to the predictive power of the demographic / background variables. Moderate and heavy drinkers expected alcohol to enhance their social and sexual pleasure, social assertiveness, and tension reduction more that light drinkers, but the groups did not differ in expected negative consequencies. Problem drinkers were found to maintain stronger alcohol-related expectancies on all 8 expectancy scales than normal drinkers. These results suggest a possible mediating role of alcohol-related expectancies in college drinking problems, and possible strategies for assessment and treatment of college students at high-risk for later drinking problems.

琉球王國의 陶祖가 된 朝鮮人 張獻功에 대하여

홍종필 명지대학교 인문과학연구소 1996 인문과학연구논총 Vol.14 No.-

滿洲朝鮮 人移民の宗敎活動について : 北間島地方を中心に

홍종필 명지대학교 인문과학연구소 1996 인문과학연구논총 Vol.15 No.-

정신병적 증상이 동반된 기면병 1예

홍승철,송정민,정종현,권용실,한진희,이성필 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.5

Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucinations and disrupted nocturnal sleep. We report a patient with a diagnosis of schizophrenia who was subsequently diagnosed as narcolepsy. A case of a 22-year-old woman with concomitant narcolepsy and psychotic symptoms was discussed from a perspective of the diagnosis and therapeutic challenges, particularly on pharmcological treatment dealing with issues raised by their coexistence.

Creutzfeldt-Jacob병 1례

홍승철,한진희,정종현,김소양,허균,이성필 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

저자들은 Creutzfeldt-Jacob병 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 약 4개월에 걸친 비교적 짧은 기간 동안 중증의 인지 기능 장애와 시각 장애, 보행장애와 하지의 약화, 불수의적 운동 등과 함께 섬망상태에까지 이르게 되어 본원 정신과에 입원하게 되었다. 정신상태 검사상, 반응시간의 지체, 언어장애와 보속증, 시간에 대한 지남력 장애, 주의 집중력 장애, 단기 및 장기 기억 장애, 추상적 사고능력 장애 등의 소견을 보였고, 이러한 증상들은 입원후 치료에도 불구하고 빠르게 악화되었다. 뇌파검사상 지속적인 다발초점성 서파가 모든 전극에서, 특히 우측 전두부에서 현저하게 나타나는 소견을 보였고, 병리조직학적 검사상 대뇌 피질에 신경손실을 동반한 해면화와 신경교 증식증을 나타냈다. 이상의 소견들은 모두 CJD의 진단에 합당하였다. We report a case of Creutzfeldt-Jacob disease and review the relevant literatures. This 56-year-old male patient was admitted to our hospital with a history of rapidly progressing cognitive dysfunction, visual disturbance, gait disturbance, weakness, involuntary movement of lower extremities, and the symptoms of delirium. On mental status examination, he showed psychomotor retardation, speech disturbance, perseveration, disorientation, impairment of short-term and long-term memory, and inability of abstract thinking. He had a rapid downhill course, along with shakiness of trunk, rigidity of the limbs, myoclonus, confusion, and finally, inability to speak or move on the bedside. On electroencephalogram(EEG), continuous multifocal show delta activities were found in all leads, especially in the right frontal areas. Brain biopsy showed, spongiosis with neuronal loss and gliosis noted at the cerebral cortex. These findings were compatible with Creutzfeldt-Jacob disease.

오키나와(沖繩)의 舊國寶였던 朝鮮鐘(興海大寺鐘)에 대하여

홍종필 명지대학교 인문과학연구소 1997 인문과학연구논총 Vol.16 No.-

農家副業으로서의 畜産現況과 그 改善方案에 關한 硏究

洪鐘旭,李熙碩,朴恒均,崔源弼,李鉉凡,金祥基 慶北大學校 1978 論文集 Vol.25-26 No.-

Recently, there have been much corncerns about the strategies which can reasonably increase farm income at the average farm level. In other words, as a result of third-term Five Year Economic Development Plan there was a remarkable gap between farm household and non-farm household incomes. Therefore, various policy tasks to eliminate this unbalanced income growth are currently being implemented. This study was carried out to identify the situation of livestock farming at general farm level, regarded as one of income generation strategies for the farm sector. Some results of the study can be summarized as follows: First of all, it was found that a group of farms which raise a small size of animals like Korean cattle, hog, and various poultry gave higher resource bases as compared with that of non-livestock farms. Secondly, it was also recognized that both farm and farm household income levels of small-scale livestock farms were higher than those of non-livestock farm group within the same region, specifically as much as approximately ￦200,000. Thirdly, it was known that the average size of animal raising per household in 0.9 head of cattle, 0.8 head of hog, and 34 lyers of poultry, respectively. To the end, according to the farm disposal practices of major by-products, only about 18 percent of total rice straws produced at individual farms was utilized for the animal raising, and about 45 percent of all the brans available at farms for the livestock enterprise. The rest of straw and brans in regarded as selling at farm level. In this respect, it may be recommended either to increase current size of animals or to expand number of livestock farms.

소비자 정보처리 관점에서 조망한 광고와 기사홍보(publicity)의 변별적 기능에 관한 개념적 고찰

홍종필 이화여자대학교 2004 사회과학연구논총 Vol.13 No.-

한 제품이나 서비스를 효과적으로 마케팅하기 위한 다각적이고도 통합적인 마케팅 커뮤니케이션 활동이 전개되고 있는 현재의 마케팅 환경에서 다양한 프로모션 믹스의 상대적인 효과는 어떻게 다르며 그 효과를 어떻게 평가할 것인가에 대한 질문이 끊임없이 대두되어 왔다. 특히 이러한 촉진 믹스 가운데 광고와 PR은 기업의 촉진 활동에 있어서 중요한 역할을 담당하여 왔으며, 최근 들어 PR의 경우 그 상대적 비중이 점차 커져가고 있다고 할 수 있다. 본 연구는 광고와 기상홍보에 대한 소비자 반응을 정보처리 관점에서 이해하고, 이를 바탕으로 체계적 연구 축적의 토대가 될 수 있는 개념적인 틀을 마련하고자 하였다. 특히 이제까지의 연구가 등한시하여 왔던 광고와 기사홍보가 소비자의 메시지 정보처리의 동기, 기회, 능력에 어떻게 영향을 주는가를 체계적으로 정리하고자 시도하였다. 이런 목적으로 본 논문은 커뮤니케이션 이론과 소비자 정보처리 이론에 근거하여 광고와 기사홍보가 어떻게 소비자의 정보처리 동기, 기회 및 능력에 영향을 미치며, 또한 이 두 촉진 요소 간의 변별적인 차이점은 무엇인지에 관한 연구명제 개발에 초점을 맞추었다. 그럼으로써 광고와 기사홍보와 같이 서로 다른 두 가지 포맷의 프로모션 활동의 효과에 대해서 체계적이고도 경험적으로 비교할 수 있는 이론적 기반을 마련하고자 하였다. 이를 통해 궁극적으로는 학계나 업계 모두에게 촉진 믹스의 의사결정과 효과적인 촉진 전략 수립과 관련하여 중요한 시사점을 제공할 수 있을 것으로 기대된다. Conventional wisdom about the relative effectiveness of various promotional tools are constantly challenged in the era of fast changing market situation. Marketers are becoming increasingly aware of the value of integrated marketing communication programs, and much attention are paid to publicity. Yet scholarly attention to this element is limited primarily to cursory textbook treatment. This paper tried to draw upon communication and information processing theory to establish a framework for the development of propositions about advertising and publicity, in terms of thier relative impact upon consumers' motivation, ability, and opportunity to process information. It also identified a need for and suggested an approach to the systematic empirical comparison of these two promotional formats.

탈력발작 유무에 따른 기면병 환자의 비교 : 임상변인, HLA-DQB1*0602, Hypocretin

정종현,홍승철,신윤경,한진희,이성필 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.1

Objectives : Narcolepsy is a sleep disorder, characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucination. Among these symptoms, cataplexy is one of the most pathognomonic symptoms in narcolepsy. This study was designed to investigate the clinical features, frequency of DQB 1 *0602 and CSF hypocretin levels in Korean narcolep-tics with cataplexy to compare with those who have not cataplexy. Methods : From August 2003 to July 2005, we selected 72 patients who have narcolepsy confirmed by nocturnal Polysomno-graphy and multiple sleep latency test (MSLT) as well as their history and clinical symptoms at Sleep Disorders Clinic of St. Vincent's Hospital, Catholic University of Korea. Patients were divided into 56 cataplexy-positive group (narcolepsy with cataplexy group) and 12 cataplexy-negative group (narcolepsy without cataplexy group). HLA typing was done in all patients for the presence of DQB 1*0602, and patients received spinal tapping to measure the level of CSF hypocretin. Clinical variables were examined by semi-structured interview for narcolepsy patients. Results : 1) In cataplexy-positive group, compared with cataplexy-negative group, the frequency ofHLA-DQB 1*0602 was found to be significantly increased (50 subjects, 89.3% vs. 8 subjects, 50.0%) (p=0.000). 2) tn 48 out of 56 cataplexy-positive patients (85.7%), hypocretin levels were decreased (≤110 pg/mI) or were below the detection limit of assay (≤40 pg/ml).However, only 6 out of 16 cataplexy-negative patients (37.5%) exhibited decreased hyopcretin level. The difference between two groups were statistically significant (p=0.000). 3) Cataplexy-positive group, compared to cataplexy-negative group, re-ported more frequent hypnagogic hallucinations (36 subjects, 64.3% vs. 4 subjects, 25.0%) (p=0.005). However, there were no significant differences in frequency or seventy of daytime sleepiness, sleep paralysis and demographic data. 4. In nocturnal polysomnography and MSLT findings, there were no significant differences in all sleep parameters between two groups. Conclusion : Higher frequency of HLA-DQB 1*0602, and lower hypocretin levels in cataplexy-positive groups than Cata-pelxy-negatives suggest that narcoleptics with cataplexy might be a etiologically different disease entity from narcoleptics without cataplexy. Additionally, Current criteria prevail for the diagnosis of narcolepsy need to be reclassified according to the presence of cataplexy or not.