A Novel Recognition Algorithm Based on Holder Coefficient Theory and Interval Gray Relation Classifier

( Jingchao Li ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.11

The traditional feature extraction algorithms for recognition of communication signals can hardly realize the balance between computational complexity and signals` interclass gathered degrees. They can hardly achieve high recognition rate at low SNR conditions. To solve this problem, a novel feature extraction algorithm based on Holder coefficient was proposed, which has the advantages of low computational complexity and good interclass gathered degree even at low SNR conditions. In this research, the selection methods of parameters and distribution properties of the extracted features regarding Holder coefficient theory were firstly explored, and then interval gray relation algorithm with improved adaptive weight was adopted to verify the effectiveness of the extracted features. Compared with traditional algorithms, the proposed algorithm can more accurately recognize signals at low SNR conditions. Simulation results show that Holder coefficient based features are stable and have good interclass gathered degree, and interval gray relation classifier with adaptive weight can achieve the recognition rate up to 87% even at the SNR of -5dB.

Expression of the Na⁺-HCO₃⁻cotransporter and its role in pH_iregulation in guinea pig salivary glands

Li, Jingchao,Koo, Na-Youn,Cho, Ik-Hyun,Kwon, Tae-Hwan,Choi, Se-Young,Lee, Sung J.,Oh, Seog B.,Kim, Joong-Soo,Park, Kyungpyo American Physiological Society 2006 American journal of physiology, Gastrointestinal a Vol.291 No.6

<P>Patterns of salivary HCO3<SUP>−</SUP>secretion vary and depend on species and gland types. However, the identities of the transporters involved in HCO3<SUP>−</SUP>transport and the underlying mechanism of intracellular pH (pHi) regulation in salivary glands still remain unclear. In this study, we examined the expression of the Na<SUP>+</SUP>-HCO3<SUP>−</SUP>cotransporter (NBC) and its role in pHiregulation in guinea pig salivary glands, which can serve as an experimental model to study HCO3<SUP>−</SUP>transport in human salivary glands. RT-PCR, immunohistochemistry, and pHimeasurements from BCECF-AM-loaded cells were performed. The amiloride-sensitive Na<SUP>+</SUP>/H<SUP>+</SUP>exchanger (NHE) played a putative role in pHiregulation in salivary acinar cells and also appeared to be involved in regulation in salivary ducts. In addition to NHE, NBC also played a role in pHiregulation in both acini and ducts. In the parotid gland, NBC1 was functionally expressed in the basolateral membrane (BLM) of acinar cells and the luminal membrane (LM) of ducts. In the submandibular gland, NBC1 was expressed only in the BLM of ducts. NBC1 expressed in these two types of salivary glands takes up HCO3<SUP>−</SUP>and is involved in pHiregulation. Although NBC3 immunoreactivity was also detected in submandibular gland acinar cells and in the ducts of both glands, it is unlikely that NBC3 plays any role in pHiregulation. We conclude that NBC1 is functionally expressed and plays a role in pHiregulation in guinea pig salivary glands but that its localization and role are different depending on the type of salivary glands.</P>

Toll-like Receptor3-mediated Induction of Chemokines in Salivary Epithelial Cells

Li, Jingchao,Jeong, Mi-Young,Bae, Ji-Hyun,Shin, Yong-Hwan,Jin, Meihong,Hang, Sung-Min,Lee, Jeong-Chai,Lee, Sung-Joong,Park, Kyung-Pyo The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.4

Toll-like receptors (TLRs) functionally expressed in salivary epithelial cells, but their roles remain elusive. Among TLRs family, TLR3 is activated by dsRNA, a byproduct of viral infection. The aim of this study was to investigate the role of TLR3 in the inflammatory immune responses using HSG cells. Reverse transcriptase-polymerase chain reaction (RT-PCR), real-time PCR and ELISA were performed to identify expression of TLRs and TLR3-mediated chemokine inductions. The chemotaxis assay of activated T lymphocytes was also performed. Treatment of HSG cells with polyinosinic: polycytidylic acid (poly(I:C)) significantly increased interferon-$\gamma$-inducible protein 10 (IP-10), interferoninducible T-cell $\alpha$ chemoattractant (I-TAC), and regulated on activation, normal T-cells expressed and secreted (RANTES) gene expressions in a concentration-dependent manner. Anti-TLR3 antibody blocked the increases of IP-10 and I-TAC genes. Poly(I:C)-induced increases of IP-10 and I-TAC were also confirmed at protein levels from cell lysates, but their release into extracellular medium was detected only in IP-10. We found that the culture media from HSG cells stimulated with poly(I:C) significantly increases T lymphocyte migration. Our results suggest that TLR3 plays an important role in chemokine induction, particularly IP-10, in salivary epithelial cells.

Toll-like Receptor3-mediated Induction of Chemokines in Salivary Epithelial Cells

Jingchao Li,정미영,배지현,신용환,진미홍,박경표,홍성민,이정채,이성중,박경표 대한약리학회 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.4

Toll-like receptors (TLRs) functionally expressed in salivary epithelial cells, but their roles remain elusive. Among TLRs family, TLR3 is activated by dsRNA, a byproduct of viral infection. The aim of this study was to investigate the role of TLR3 in the inflammatory immune responses using HSG cells. Reverse transcriptase-polymerase chain reaction (RT-PCR), real-time PCR and ELISA were performed to identify expression of TLRs and TLR3-mediated chemokine inductions. The chemotaxis assay of activated T lymphocytes was also performed. Treatment of HSG cells with polyinosinic: polycytidylic acid (poly(I:C)) significantly increased interferon-γ-inducible protein 10 (IP-10), interferon- inducible T-cell α chemoattractant (I-TAC), and regulated on activation, normal T-cells expressed and secreted (RANTES) gene expressions in a concentration-dependent manner. Anti-TLR3 antibody blocked the increases of IP-10 and I-TAC genes. Poly(I:C)-induced increases of IP-10 and I-TAC were also confirmed at protein levels from cell lysates, but their release into extracellular medium was detected only in IP-10. We found that the culture media from HSG cells stimulated with poly(I:C) significantly increases T lymphocyte migration. Our results suggest that TLR3 plays an important role in chemokine induction, particularly IP-10, in salivary epithelial cells.

A New Robust Signal Recognition Approach Based on Holder Cloud Features under Varying SNR Environment

( Jingchao Li ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.12

The unstable characteristic values of communication signals along with the varying SNR (Signal Noise Ratio) environment make it difficult to identify the modulations of signals. Most of relevant literature revolves around signal recognition under stable SNR, and not applicable for signal recognition at varying SNR. To solve the problem, this research developed a novel communication signal recognition algorithm based on Holder coefficient and cloud theory. In this algorithm, the two-dimensional (2D) Holder coefficient characteristics of communication signals were firstly calculated, and then according to the distribution characteristics of Holder coefficient under varying SNR environment, the digital characteristics of cloud model such as expectation, entropy, and hyper entropy are calculated to constitute the three-dimensional (3D) digital cloud characteristics of Holder coefficient value, which aims to improve the recognition rate of the communication signals. Compared with traditional algorithms, the developed algorithm can describe the signals` features more accurately under varying SNR environment. The results from the numerical simulation show that the developed 3D feature extraction algorithm based on Holder coefficient cloud features performs better anti-noise ability, and the classifier based on interval gray relation theory can achieve a recognition rate up to 84.0%, even when the SNR varies from -17dB to -12dB.

Communication Modulation Signal Recognition Algorithm Based on Entropy Cloud Characteristics

Yibing Li,Jie Chen,Dandan Liu,Jingchao Li 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.5

Communication modulation signal recognition, as an emerging technology, has been widely used in the field of communication reconnaissance. It is generally known that the characteristics of communication modulation signals under low SNR environment is difficult to extract. To solve this problem, a novel modulation signal feature extraction algorithm based on entropy cloud characteristics is put forward in three steps by this paper. Firstly, it extracts entropy characteristics of the modification signal, which introduce the exponential entropy to construct two-dimensional feature entropy with shannon and exponential entropy for a better signal recognition performance. Then, it extracts cloud digital characteristics of information entropy to build three-dimensional feature, which can depict the modulation type characteristics of the signal. Finally, it uses grey correlation classifier for signal identification. By means of simulation, it can be seen that the new algorithm has overcome the defection that signal characteristics are unstable and difficult to extract under low SNR environment in the traditional method. So the new algorithm is available and effective for the signal identification under low SNR environment, thus achieves the goal of the signal classification.

Antibody-conjugated gold nanoparticles as nanotransducers for second near-infrared photo-stimulation of neurons in rats

Liu Jiansheng,Li Jiajia,Zhang Shu,Ding Mengbin,Yu Ningyue,Li Jingchao,Wang Xiuhui,Li Zhaohui 나노기술연구협의회 2022 Nano Convergence Vol.9 No.13

Infrared neural stimulation with the assistance of photothermal transducers holds great promise as a mini-invasive neural modulation modality. Optical nanoparticles with the absorption in the near-infrared (NIR) window have emerged as excellent photothermal transducers due to their good biocompatibility, surface modifiability, and tunable optical absorption. However, poor activation efficiency and limited stimulation depth are main predicaments encountered in the neural stimulation mediated by these nanoparticles. In this study, we prepared a targeted polydopamine (PDA)-coated gold (Au) nanoparticles with specific binding to thermo-sensitive ion channel as nanotransducers for second near-infrared (NIR-II) photo-stimulation of neurons in rats. The targeted Au nanoparticles were constructed via conjugation of anti-TRPV1 antibody with PEGylated PDA-coated Au nanoparticles and thus exhibited potent photothermal performance property in the second NIR (NIR-II) window and converted NIR-II light to heat to rapidly activate Ca 2+ influx of neurons in vitro. Furthermore, wireless photothermal stimulation of neurons in living rat successfully evoke excitation in neurons in the targeted brain region as deep as 5 mm beneath cortex. This study thus demonstrates a remote-controlled strategy for neuromodulation using photothermal nanotransducers.

Ca2+-activated K+ Currents of Pancreatic Duct Cells in Guinea-pig

이한욱,Jingchao Li,구나연,Zheng Gen Piao,황성민,한재웅,최한샘,이종흔,김중수,박경표 대한약리학회 2004 The Korean Journal of Physiology & Pharmacology Vol.8 No.6

There are numerous studies on transepithelial transports in duct cells including Cl- and/or HCO3-. However, studies on transepithelial K+ transport of normal duct cells in exocrine glands are scarce. In the present study, we examined the characteristics of K+ currents in single duct cells isolated from guinea pig pancreas, using a whole-cell patch clamp technique. Both Cl- and K+ conductance were found with KCl rich pipette solutions. When the bath solution was changed to low Cl-, reversal potentials shifted to the negative side, -75±4 mV, suggesting that this current is dominantly selective to K+. We then characterized this outward rectifying K+ current and examined its Ca2+ dependency. The K+ currents were activated by intracellular Ca2+. 100 nM or 500 nM Ca2+ in pipette significantly (P<0.05) increased outward currents (currents were normalized, 76.8±7.9 pA, n=4 or 107.9±35.5 pA, n=6) at +100 mV membrane potential, compared to those with 0 nM Ca2+ in pipette (27.8±3.7 pA, n=6). We next examined whether this K+ current, recorded with 100 nM Ca2+ in pipette, was inhibited by various inhibitors, including Ba2+, TEA and iberiotoxin. The currents were inhibited by 40.4±% (n=3), 87.0±% (n=5) and 82.5±% (n=9) by 1 mM Ba2+, 5 mM TEA and 100 nM iberiotoxin, respectively. Particularly, an almost complete inhibition of the current by 100 nM iberiotoxin further confirmed that this current was activated by intracellular Ca2+. The K+ current may play a role in secretory process, since recycling of K+ is critical for the initiation and sustaining of Cl- or HCO3- secretion in these cells.

Hybrid Full Frequency Precoding for Integrated Remote Wireless Sensor and Multibeam Satellite Networks

( Hongjun Li ),( Feihong Dong ),( Xiangwu Gong ),( Changliang Deng ),( Luliang Jia ),( Jingchao Wang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.6

This paper investigates an efficient transmission scheme for the remote wireless sensors to receive information which is rarely discussed in the integrated remote wireless sensor and multibeam satellite networks (IWSMSNs). The networks can be employed to exchange sensing information for emergency scenario, ocean scenario, and so on, which are isolated from available terrestrial networks. As the efficient transmission link is important to the IWSMSNs, we propose a hybrid full frequency (HFF) precoding by taking advantage of frequency reuse and multiple-input multiple-output (MIMO) precoding. Considering energy efficiency and sinks fairness are crucial to transmission link, thus the HFF precoding problems are formulated as transmit power minimization (TPM) and max-min fair (MMF) received signal to interference plus noise ratio (SINR) problems, which can be transformed to indefinite quadratic optimization programs. Then this paper presents a semi-definite programming (SDP) algorithm to solve the problems for the IWSMSNs. The promising potential of HFF for the real IWSMSNs is demonstrated through simulations.

Expression of Translationally Controlled Tumor Protein (TCTP) Gene of Dirofilaria immitis Guided by Transcriptomic Screening

Yan Fu,Jingchao Lan,Xuhang Wu,Deying Yang,Zhihe Zhang,Huaming Nie,Rong Hou,Runhui Zhang,Wanpeng Zheng,Yue Xie,Ning Yan,Zhi Yang,Chengdong Wang,Li Luo,Li Liu,Xiaobin Gu,Shuxian Wang,Xuerong Peng,Guangy 대한기생충학열대의학회 2014 The Korean Journal of Parasitology Vol.52 No.1