대학생의 우울정도 : 간호학전공과 타전공대학생을 중심으로

김지연,류나은,이소라,이지희,정윤정,주지연,황인혜 이화여자대학교 간호과학대학 2012 이화간호학회지 Vol.- No.46

Purpose: This study was designed to investigate sample’s general characteristics and compare depression degree among sample’s general characteristics and students’ major(nursing vs. other major). Methods: The subjects consisted of 318 university students. Data was collected by self-reported questionnaires, which were constructed BDI score. Data was analyzed by the SPSS/PC WIN 19.0 program. Results: The depression of nursing students and other major students was not significantly different according to BDI score. Statistically significant difference was identified among sleeping. Conclusion: Specific study focused on the practice time should be done to confirm the depression of nursing major and other majors. Detailed support programs which specifically deal with sleeping should be developed to effectively reduce the harmful effects of individual vulnerability. Therefore, prevention and management system to reduce depression degree for university students is needed.

11β-수산화효소 결핍에 의한 선천성 부신증식증 1예

류옥현,류혜진,박수연,권순범,박상수,김희영,이계원,서지아,오정헌,김신곤,김난희,최경묵,백세현,최동섭 대한내분비학회 2004 Endocrinology and metabolism Vol.19 No.1

저자들은 국내에서 처음으로 음핵 비대와 지속적인 질출혈을 주소로 내원한 19세 여성에서 고혈압이 동반되지 않으면서 11 -수산화효소 결핍으로 인한 선천성부신증식증을 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다. Congenital adrenal hyperplasia refers to a group of autosomal recessive disorders that is defective in the synthesis of cortisol. The enzymes most often affected are 21-hydroxylase and 11 - hydroxylase. The low levels of cortisol stimulate the pituitary gland to release ACTH. Chronic elevation of the ACTH level causes bilateral adrenal hyperplasia and a secondary increase in androgen formation. We examined a 19 year-old woman presented with clitoral hypertrophy and vaginal spotting. The subjects basal level of serum cortisol was low, but the serum levels of ACTH, 17a-hydroxyprogesterone, deoxy-corticosterone were elevated. The urinary excretions of 17-ketosteroids and 17-hydroxycorticosteroids were also increased. The karyotyping study and transrectal ultrasonography showed normal findings. The patient underwent clitoris reduction surgery and received hydrocortisone. To the best of our knowledge, this is the first case of 11 -hydroxylase deficiency in Korea (J Kor Soc Endocrinol 19:58∼63, 2004).

폐지 소각 공정의 전과정평가

정수정,류지연,허탁 한국전과정평가학회 2004 한국전과정평가학회지 Vol.5 No.1

본 연구에서는 전과정평가(Life Cycle Assessment, LCA)기법을 이용하여 폐지 소각 공정에 대한 전과정영향평가를 수행하였다. 폐지 1kg을 소각할 경우, 전력 0.089kwh, 용수 0.86kg, 각종 화학약품 0.0086kg이 투입되고 대기배출물로 이산화탄소는 1.13kg, NOx는 0.0015kg 발생되고 바닥재와 비산재는 각각 0.1kg, 0.013kg 발생하며 폐열을 이용한 스팀 에너지 3.42MJ이 회수된다. 소각 공정 자체에 의한 이산화탄소 배출은 1.13kg/f.u.이며 에너지 회수로 인하여 0.32kg/f.u.가 환경 이득이 되어 최종적으로 0.82kg /f.u.의 이산화탄소가 발생한다. 전과정 영향평가 결과, 지구온난화가 77.7%, 자원고갈 6.3%, 산성화, 부영양화, 생태독성 순으로 조사되었다. 이산화탄소의 주원인인 탄소함량을 줄이면 환경영향이 줄어들 수 있으나 일반적인 종이의 탄소함량은 일정하므로 이는 해결방안으로 적절치 못하다. 그렇다면 폐열 에너지 회수율을 높이는 것이 전체 환경부하 저감에 도움이 될 것이다. 회수율을 높이는 방안으로는 수분함량을 줄이는 것, 즉 폐지와 함께 섞여 들어오는 음식물 쓰레기의 양을 줄이면 에너지 회수율을 좀 더 증가시켜 환경부하를 저감하는 하나의 방안이 될 것이다. 또한 보다 근본적인 해결방안으로는 되도록이면 현재 56% 정도인 폐지의 재활용률을 높여 폐지소각으로 인한 환경부하 발생을 감소시켜야 할 것이다. This study is about practicing LCA on the incinerating waste paper. One kilogram of waste paper needs a 0.089kwh of electricity, 0.86kg of water and 0.0086kg of various chemicals while burned. As a result, 1.13kg of CO2, 0.0015kg of NOx are eliminated as the outcome to the air. Also, 0.1kg of ashs and 0.013kg of arsenic acids are produced. Steam caused by using waste heat is recovered by 3.42MJ. The exhaust of CO2 in the stage of incinerating itself is 1.13kg/f.u. but it gets 0.32kg/f.u. from the energy recovery, so, the total counts 0.82kg/f.u. The order of impact categories from the LCA result is global warming(77.7%), abiotic resource depletion(6.3%) and acidification, eutrophication, ecotoxicity. Even though it might somewhat reduce the bad effect on ecology to cut back the amount of carbon, which is the main ingredient in CO2, however, given that the amount of carbon in paper remains unchanged, that is not the proper plan. Now we can suppose that promote energy recovery would help minimizing the overall burden on the environment. One solution to increase the rate of energy recovery is reducing the content of water in food waste came along with waste paper. And this results in lessening the burden on the environment. Promoting the recycling rate of waste paper, which accounts 56% now, might be the basic solution to reduce the burden on ecology generated from the incineration of paper.

의예과 학생들의 성격유형검사(MBTI)의 특성

오윤경,장진영,박상학,류소연 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Pmpose: To investigate the characteristics of Myers-Briggs Type Indicator (MBTI) in premedical students of one medical college and to compare the personality profiles of them with those of other studies which involved the K-orean university students and other country population. Mateiials and Methods: The MBTI was used to measure the personality profiles of premedical students at the Center for Teaching & Leaming of Chosun University. One hundred and twenty five premedical students participated in this study and the MBTI profiles of them were compared to those of K-orean university students (1,441 persons), i.e. their potential patients and those of the United Kingdom (UK.) Population (1,634 persons) and a sample of UK- doctors (313 persons) of one medical college involved in other studies. Results: The premedical students had a preference for Introversion (62%) rather than Extraversion (38%), Sensing (70%) rather than Intuition (30%), Thinking (66%) rather than Feeling (34%), and Judging (57%) rather than Perceiving (43%). There were more Thinking (66% vs 57%, p=0.071) in the premedical students than in K-orean university students with borderline significance. There were significantly more Thinking (66% vs 46%, P=0.000) and more Introversion (62% vs 48%, p=0.002) than in UK- adult population. Also there were significantly more Sensing (62% vs 48%, p=0.002), significantly less Judging (57% vs 68%, P=0.034), and more Introversion (62% vs 53%, 0=0.094) with borderline significance than in UK doctors. But no difference was shown in Thinking between the premedical students and UK- doctors, Conclusion: The personality profiles of the premedical students in this study differed in Thinking with borderline significance from K-orean university students and significantly differed from the UK adult population in Thinking and Introversion showing the cultural difference. No difference of Thinking between the premedical students and UK doctors despite of cultural difference suggests the correlation between the Thinking and medical professional choice.

골격근 근형질세망의 ATPase활성도에 대한 Vanillylnonanamide의 영향

박경섭,홍장희,류영수,성지연,허강민,임종호,이재흔,석정호 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.2

To investigate the effect of vanillylnonanamide(VN) on the ATPase activity of the sarcoplasmic reticulum(SR) of the skeletal muscle, we prepared the SR vesicles from the back muscle of the rabbit, and measured ATPase activity. The results as follows: Ca-ATPase activity was about 50% in the total ATPase activity of skeletal muscular SR. In the reaction mixture with calcium, 100μM VN increased ATPase activity to 20%, and 100 nM and 10 μM thapsigargin(THP) inhibited the ATPase activity to 50% and 60%, respectively. And 100 μM VN plus 100 nM or 10 μM THP more inhibited ATPase activity than THP alone did it. However, without calcium, 100μM VN did not affect ATPase activity, and 10 μM THP inhibited it to 41%, but VN plus THP inhibited it to 31%. The above results show that VN in the reaction mixture with or without calcium has the different action to ATPase activity when it is used alone or together with Ca-ATPase inhibitor THP. This suggests that VN might increase or decrease the skeletal SR Ca-ATPase activity through affecting the lipid membrane around the Ca-ATPase.

OB-11 : Placental microRNAs as potential biomarkers for noninvasive detection of trisomy 21

( Min Hyoung Kim ),( Ji Hyae Lim ),( Da Eun Lee ),( Jung Yeol Han ),( Moon Young Kim ),( You Jung Han ),( So Yeon Park ),( Hyun Mee Ryu1 ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: The discovery of fetal nucleic acids in the plasma of pregnant women has led to the development of noninvasive prenatal testing (NIPT). The objective of this study was to discover a panel of placental miRNAs as potential novel biomarkers for NIPT of fetal T21 and to predict the biological functions of new biomarkers using bioinformatics tools. 방법: Using microarray-based genome-wide expression profiling, we compared the expression levels of miRNAs in whole blood samples from non-pregnant women, whole blood samples from pregnant women, and fetal placenta samples from pregnant women with euploid or T21 fetuses. We analyzed the differentially expressed miRNAs according to the presence or absence of disease and tissue type (p value <0.05 and two-fold expression change). Potential target genes of miRNAs were predicted using the miRBase program. To predict their functions, the functional annotation tools provided by the WebGestalt database were used. 결과: We identified 299 miRNAs which reasonably separate the whole blood from the placenta. Among the identified miRNAs, 150 miRNAs were up-regulated in the placenta, and 149 miRNAs were down-regulated. Most of the up-regulated miRNAs in the placenta were members of the mir-498, mir-379, and mir-127 clusters as placenta specific miRNA located on hsa19 and hsa14. Among the up-regulated miRNAs in the placenta, mir-1973 and mir-3196 were expressed at higher levels in the T21 placenta than in the euploid placenta. The two miRNAs potentially regulate 203 target genes that are involved in developmentof brain, central nervous system, and nervous system. Interestingly, the genes are significantly associated with T21-related disorder such as congenital abnormalities, mental disorders, and nervous system diseases. 결론: Our study indicates placenta-specific miRNAs that may be potential biomarkers for NIPT of fetal T21 and provides new insights into the molecular mechanisms of T21 via regulation of miRNAs.

Biocontrol of damping off(Rhizoctonia solani) in cucumber by Trichoderma asperellum(T-5)

Ji-Yeon Ryu(유지연),Min-Young Cho(조민영),Sung-Jae Kim(김성재),Tak-Eun Lee(이은탁),Ro-Dong Park(박노동),Kil-Yong Kim(김길용) 한국토양비료학회 2006 한국토양비료학회 학술발표회 초록집 Vol.2006 No.5

The Effect of Density-of-State on the Temperature and Gate Bias-Induced Instability of InGaZnO Thin Film Transistors

Ji, Kwang Hwan,Kim, Ji-In,Jung, Hong Yoon,Park, Se Yeob,Mo, Yeon-Gon,Jeong, Jong Han,Kwon, Jang-Yeon,Ryu, Myung-Kwan,Lee, Sang Yoon,Choi, Rino,Jeong, Jae Kyeong The Electrochemical Society 2010 Journal of the Electrochemical Society Vol.157 No.11

Can blood components with age-related changes influence the aging of endothelial cells? (초)

( Ji Yeon Noh ),( Sang Ho Oh ),( Ju Hee Lee ),( Yeon Sook Kwon ),( Dong Jin Ryu ),( Kwang Hoon Lee ) 대한피부과학회 2009 초록집 Vol.47 No.20

Early Differentiation of Stress Cardiomyopathy from Acute Anterior Wall Myocardial Using Changing Cardiac Enzyme Patterns

Ji Yeon Hong,Sung Kee Ryu,Ji Young Park,Sung Hun Park,Jaewoong Choi 한국심초음파학회 2021 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.29 No.3

BACKGROUND: Most patients with acute anterior wall ST elevation myocardial infarction (STEMI) or stress cardiomyopathy (SCMP) show elevations in cardiac enzymes that peak within 24 hours. The changing pattern of cardiac enzymes can be an early clue to the differentiation of anterior STEMI and SCMP. METHODS: This study was a retrospective analysis (matching cases and respective control subjects) performed at a single center. We compared 27 patients with SCMP and 30 patients with anterior STEMI. We used laboratory data included cardiac marker, such as the initial creatine kinase MB (CK-MB) fraction and troponin T (Tn-T), at admission and peak CK-MB and Tn-T at follow up. RESULTS: The mean age was 69.3 ± 14.1 years, and 38.6% of patients were female. The SCMP patients were older, more often female, and had lower left ventricular ejection fractions than the anterior STEMI patients. The initial CK-MB was higher in the anterior STEMI group than in the SCMP group. In contrast, the initial Tn-T level was not significantly different between the 2 groups. Peak CK-MB and Tn-T levels and change from initial levels were significantly greater in the anterior STEMI group than they were in the SCMP group. SCMP could be differentiated from anterior STEMI based on peak CK-MB > 46.65 ng/mL or Tn-T > 1.56 ng/mL. CONCLUSIONS: Follow-up changes in cardiac enzymes can be an effective early tool for differentiating SCMP from anterior STEMI.