응급실에 내원한 환자에서 어지럼증의 원인과 임상양상의 분석

문원식,정경운,위준선,문정미,전병조,김용권,소정일,류진호,허탁,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: Recently, The number of patients who have been complaining of the vertigo or dizziness has been increasing due to rapid growth of elderly population and senile disease. The differentiation of dizzy patients is not familiar to most emergency physicians. This study was designed to differentiate true vertigo and to investigate the clinical difference among central vertigo, peripheral vertigo, and other causes of dizziness. Methods: The authors analyzed the cases of 237 dizzy patients who visited the emergency department of Chonnam University Hospital during the recent 2 years. For the base of dizziness, associated past illnesses, severity, nystagmus type, and the causes of central and peripheral vertigo. Results: Female patients were 142(59.9%) and male patients were 95(40.1%). The most common age group was the 6th decade. The origin of dizziness was classified as peripheral cause(25.3%), central cause(32.9%), and others(41.8%). As to nature of the dizziness, the rotatory sense was dominant in peripheral vertigo and the floating sense and blurred vision in central vertigo. Peripheral vertigo was triggered by position change of head and body, and central vertigo by the eye movement. Audiograms I showed that most patients with central vertigo had normal hearing, but 46.7% of thoswith peripheral vertigo had an abnormal hearing disturbance. Nystagmus was more prevalent in peripheral vertigo Conclusion: History taking and physical examination played an important role in the diagnosis of dizzy patients. An important part of the diagnosis of a dizzy patient could be to evaluate the peripheral origin, the central origin and others causes. Because central vertigo may be associated with a significant neurological pathology, spectral radiological studies, including MRI and CT, are mandatory to rule out a devastating brain lesion.

공탄성시스템의 확률론적 제어에 대한 실험적 연구

김대중,박상태,정재욱,허훈,Kim, Dae-Jung,Park, Sang-Tae,Jeong, Jae-Uk,Heo, Hun 대한기계학회 1999 大韓機械學會論文集A Vol.23 No.11

A Newly proposed control methodology applied to the aeroelastic system experiencing flutter is investigated and its performance is verified experimentally. The flexible cantilever beam slicked with piezofilm sensor and piezoceramic actuator is modelled in physical domain. Dynamic moment equation for the system is derived via Ito's stochastic differential equation and F-P-K equation. Also system's characteristics in stochastic domain is analyzed simultaneously. LQG controller is designed and used in physical and stochastic domain. It is shown experimentally that the vibration of beam is controlled effectively by designed LQG controller in physical domain. By comparing the result with that of LQG controller designed in stochastic domain, it is shown that the new control method, called Heo-stochastic control technique, has better performance as a controller.

Impact of Interferon-Based Treatment on Quality of Life and Work Related Productivity from the Korean Cohort in the MOSAIC Study

( Sang Hoon Ahn ),( Won Hyeok Choe ),( Yoon Jun Kim ),( Jeong Heo ),( Dorota Latarska-smuga ),( Jiho Kang ),( Seung Woon Paik ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Chronic Hepatitis C Virus (HCV) infection increases the risk for progressive liver disease, hepatocellular carcinoma and negatively impacts the patient’s quality of life. HCV treatment is evolving with direct acting antivirals but IFN based therapy has been the standard of care for many years and remains available in some countries. The MOSAIC study aims to characterize patients with chronic HCV infection and assess the impact of IFN-containing treatment on health-related quality of life, work related productivity and health care utilization. Methods: MOSAIC is an international prospective multicenter observational study that has been conducted in 20 countries. Consecutive patients with chronic HCV infection were enrolled and those who initiated an IFN based regimen were prospectively followed for 48 weeks. We report results from the Korean cohort Results: 100 patients were enrolled: 86 were treatment naïve and 14 were treatment experienced. 33 patients initiated an IFN based regimen: 6 patients started IFN + RBV, 26 patients started Peg-IFN + RBV, none started Peg-IFN + RBV + DAA and 1 patient received other treatment. Among the treated cohort, demographic and disease characteristics were the following: the mean age was 54.5 years; 14 patients were male. 14 had minimal or no fibrosis, 2 portal fibrosis, 3 bridging fibrosis and 6 patients suffered from cirrhosis. HCV Genotype distribution was as follows: genotype 1: 11; genotype 2: 19 and genotype 3: 3. Table 1 describes the results at baseline and changes over 4, 12 and 48 weeks and end-of-treatment (EOT) for the quality of life and work productivity outcome measures (EQ-5D-5L, HCV-PRO and WPAI). Conclusions: Results from the Korean cohort of the MOSAIC study show a moderate trend for deterioration of health-related quality of life and work productivity associated with IFN based treatment for patients with chronic HCV infection during treatment period. Acknowledgements: The design, study conduct, analysis, and financial support of MOSAIC study were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the content of the abstract. All authors had access to all relevant data and participated in writing, review, and approval of this abstract. Medical writing support was provided by Olivier Van de Steen of Medeor-consulting, funded by AbbVie. Disclosures: Sang Hoon Ahn: served as an advisor and lecturer for Bristol-Myers Squibb, Gilead Sciences, F.Hoffmann-La Roche, Merck, AbbVie, and has received unrestricted grants from Bristol-Myers Squibb, Gilead Sciences, and F. Hoffmann-La Roche for investigator- initiated trials Won Hyeok Choe: Nothing to disclosure Yoon Jun Kim: Nothing to disclosure Jeong Heo: received a grant from GSK; Research support from BMS, and Roche; Advisor for Abbvie, BMS, Gilead Sciences, Pharma Essentia, SillaJen, and Johnson & Johnson. Dorota Latarska-Smuga, Jiho Kang: are employees of AbbVie, Inc. and may hold stock or stock options. Seung Woon Paik: received grant and research support from AbbVie, BMS, Gilead, GSK, Merck, Novartis, and Roche

신경회로망을 이용한 호 접수제어기

허정석,양성룡 울산대학교 1993 공학연구논문집 Vol.24 No.1

B-ISDN의 전송 및 교환 기법으로 정착되고 있는 ATM망의 폭주제어를 위하여, 신경회로망을 이용한 호 접수 제어기를 설계한다. 신경회로망을 이용한 호 접수제어는 가입자가 선언한 트래픽 기술인자의 불확실성에 대한 정보를 제어기가 가지고 있기 때문에, 실제 트래픽이 호 설정요구시 협약된 트래픽의 특성과 다소 상이하더라도 견고성(Robustness) 있는 트래픽 제어를 할 수 있는 장점을 가지고 있다. 본 연구에서는 신경회로망 제어기를 보다 효율적으로 학습시킬 수 있도록 두가지 학습 패턴 테이블(호 연결 요청 수락 패턴 테이블과 호 연결 요청 거절 패턴 테이블)을 이용하는 학습 알고리즘을 제안한다. 또한 모의 실험을 통하여, 제안한 신경회로망 호 접수 제어기의 성능을 분석한다. This paper describes a call admission controller by neural network to control the traffic in ATM network for service quality. Because the information of the traffic descriptor declared by users has a characteristic of uncertainty, the design and implementation of efficient controller in the network is very difficult task. The proposed ATM call admission controller by neural network is adaptive and easy to implement. We use two learning table for efficient learning of back-propagation neural network in controller. The performance of the proposed call admission controller is evaluated by simulation, and the results are compared with those of the other control technique.

노인의 운동참여와 주관적 건강인지에 따른 심리적 안녕감

허정식 한국스포츠심리학회 2003 한국스포츠심리학회지 Vol.14 No.2

본 연구는 노인의 운동참여(운동빈도와 운동시간)와 주관적 건강인지(건강상태와 체력인지)가 심리적 안녕감에 미치는 영향을 밝히기 위하여 수행되었다. 60세 이상 278명의 노인(남: 182, 65.4%, 여: 96, 34.6%)들이 본 연구에 참여하였다. 이들 중 규칙적으로 운동에 참여하는 노인은 230명(82.7%)였으며 전혀 참여하지 않은 노인은 48(17.3%)명이었다. 검사도구는 김명소, 김혜원, 차경호(2001)이 한국판 심리적 안녕감 질문지를 이용하였다. 수집된 자료는 운동참여와 주관적 건강인지에 따라 평균과 표준편차를 산출하였으며 이원변량분석을 실시하였다. 결과는 첫째, 운동참여 노인과 비참여 노인의 심리적 안녕감(자아수용, 환경 통제력, 대인관계, 삶의 목적, 개인적 성장, 자율성)을 통계적으로 유의한 차이가 있었다. 둘째, 운동참여만을 대상으로 하여 분석한 바, 자아수용과 환경 통제력, 개인적 성장 요인은 운동빈도와 주관적 체력인지에 의하여 차이가 있었다. 자율성은 운동참여와 주관적 건강인지에 따른 차이가 나타나지 않았다. 노인의 운동참여와 주관적 건강인지는 심리적 안녕감에 영향을 미치는 것으로 밝혀졌다. The purpose of this study was to examine the effects of exercise participation(exercise frequency and movement time) and subjective health evaluation(health status and physical fitness level) on the psychological well-being. Total of 278 older populations over 60 years-old(male: 182, female: 96) in Gunsan city participated in this study. Among these subjects, 230 peoples(82.7%) participated in exercise event of health center regularly, but 48 peoples(17.3%) didn't participated. Mean age of subjects were 66.8±4.5. The following scales were used for the purpose of this study. ⑴ sport-participation scale made by researcher ⑵ psychological well-being scale. The results were as follows; 1. There was significant difference in the psychological well-being(self-acceptance, environmental mastery, positive relationship, autonomy, purpose in life, personal growth) between exercise participated-populations and exercise non-participated populations statistically. 2. There was significant difference in the factors of self-acceptance, environmental mastery, and personal growth as a function of exercise frequeny and subjective physical fitness level. 3. There was significant difference in the factors of positive relationship and purpose in life as a function of subjective health status level. 4. There was not significant difference in the autonomy factor as a function of exercise participation and subjective health evaluation. The results of this investigation have found out that exercise participation have effect on the psychological well-being of the elderly via enhancing the physical fitness and subjective health evaluation.

발광다이오드를 이용한 광질과 일장조절이 '딕시 화이트' 미니 시클라멘의 개화와 생장에 미치는 영향

허정욱,이춘우,백기엽 충북대학교 첨단원예기술개발연구센터 2000 연구보고서 Vol.5 No.-

The study was conducted to investigate the effect of different light qualities and day lengths controlled by using Light-Emitting Diode (LED) of blue, red, or blue plus red provided by LED System on flowering and growth of F1 Cyclamen miniature. Cyclamen persicum 'Dixie White' seedlings which have raised for 170 days after sowing were grown under conditions of 20° C air temperature and 60% relative humidity. Day length was controlled by blue, re, or blue plus red light (1:1 in energy ratio) with 10 or 12 hr for 63 days. Photosynthetic photon flux in the treatments with 10 or 12 hr was about 100 or 83 μmol m-2 s-1, respectively. Fluorescent lamp treatment of 12 hr day length was considered as a control. Flowering and growth in all the treatments were significantly affected by light quality or day length tested in the experiment. Number of flowers, which opened above the leaf canopy, was higher in red light treatment with 10 hr day length than that in control. Days to flowering were the shortest in day length treatment of 10 hr per day with blue plus red light among the treatments. Blooming period was also the longest in red treatment regardless of day length and mixture light treatment, and thus above 20 days prolonged than that in control. Otherwise, number of unfolded leaves or net photosynthetic rate was not significantly affected by the different light qualities and day lengths.

二次元 彈性有限要所解析에서의 效果的인 Mesh 構成에 관한 硏究

허정환,양원호 成均館大學校 科學技術硏究所 1991 論文集 Vol.42 No.1

Finite element method is widely used in analysis of engineering problems such as mechanical design and structural analysis. Recently, its use has been increased according as its rapid developement of theory, computer hardware and good general-purpose sotfwares. Due to such developement, complex and various engineering problems are analyzed quickly. But, because much cost are consumed in preprocessing, applicative efficiency of finite element analysis doesn't come up to such development. And finite element analysis depends upon experience of user in modeling, mesh design and analytic method. Therefore, user must be accustomed to use finite element method which is a burden to designer and user. Thus automatization of adaptive mesh generation is imperative to reduce much cost. There are many kinds of the method for automatic mesh generation such as node connection method, mapping method, cell decomposition method, etc. In this study, however, discrete transfinite mapping were used. And C language was used in automatic mesh generation routine. Error indicator and error estimator are defined using error of energy norm. Synthetic results of above study are as follows 1) The mesh which has good correlation with boundary curve is obtained using discrete transfinite mapping. 2) User input error can be minimized by minimum input data. 3) Fine mesh is easily generated using weight value, therefore drawback of discrete transfinite mapping method is settled. 4) User can easily use the program using pull-down menu and and pop-up window. 5) Mesh refinement well be applicated in stress concentration problems.

노인의 운동참가 정도에 따른 신체적 자기개념

허정식 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study was to examine the differences of physical self-concept according to the exercise participation level in old men. Total of 278 subjects over 60 years old (male: 182, female: 96) in Gunsan city participated in this study. The independent variables were exercise frequency and period of exercise time, and dependent variables was physical self-concept. The survey tools used in this study was the Physical Self-Concept questionnaire in korean version by Kim, Beuong-Jun(2001). The average and standard deviation were computed with the collected data according to the exercise participation(participation vs. non-participation) and sex(male vs. female) and the levels of exercise participation. The results were as follows; 1. The exercise participation group is higher than non-participation group in the sports capability, health, appearance, physical activity, self-respect, flexibility, endurance, muscle strength, general physical factors, but there is not difference in the fat/slenderness. 2. The male subjects group is higher than female group in the sports capability, physical activity, self-respect, flexibility, endurance, muscle strength, general physical factors, but there is not difference in the health, appearance, fat/slenderness. 3. There was significant difference in the factors of sports capability, endurance, muscle strength as a function of exercise frequency and period of exercise time level. 4. There was significant difference in the factors of appearance, health, self-respect, general physical factors according to period of exercise time level. 5. There was significant difference in the factors of physical activity, flexibility according to exercise frequency, but there is not difference in the fat/slenderness factor.

세계화와 지식기반경제시대에서의 경제교육 담당교사들의 경제인식 능력 및 경제의식 조사 연구

허인숙,최병모,김정호 경북대학교 사범대학 부속 중등교육연구소 2005 중등교육연구 Vol.53 No.2

세계화와 지식기반경제 사회에서 요구되는 시민을 육성하기 위해서는 실질적인 경제교육의 주체라 할 수 있는 경제교육 담당교사들에 대한 객관적이고 실증적인 조사가 무엇보다 먼저 이루어져야 한다고 본다. 이러한 필요성을 인식하여 본 연구는 현행 학교교육에서 경제교육 담당교사들에 대한 경제인식 능력과 경제의식을 파악하여 교사들의 세계화와 지식기반경제시대에 대한 현 좌표를 살펴보고, 교사훈련기관인 사범대학이나 교육대학의 교육과정과 교사교육 연수프로그램에 있어서의 개선점에 대한 시사점을 찾아 세계화와 지식기반경제시대에서 요구되는 바람직한 경제교육의 방향을 모색하는데 있다. 본 연구의 목적 달성을 위해 경제교육 담당교사들의 경제인식 능력 및 경제의식에 대한 조사는 네 가지 영역, 즉 '대학시절과 연수과정에서 이수한 경제관련 과목에 대한 내용', '세계화와 지식기반사회에서의 우리 경제현안에 관련된 내용', '지식기반사회에서의 정보소양 능력에 관련된 내용', 그리고 '세계화시대에서의 경제소양에 관련된 내용'으로 이루어졌고, 이 네 가지 영역에 대한 조사는 전국 초 · 중 · 고등학교 경제교육 담당교사를 대상으로 설문지를 통해 이루어졌다. 연구조사를 통해 얻어진 결론은 우선 직전교육을 담당하는 대학의 교육과정뿐 아니라 교사들에게 새로운 경제 환경을 올바르게 인식할 수 있도록 미리 대비시키는 연수과정이 매우 불충분 한 것 같다. The purpose of this study intends to understand the economic recognition and awareness of economic teachers in the present school education field, to inspect the present aspects of the age of globalization and knowledge-based economy, to seek the suggestion of the improvements in the curriculum and training program of the institute of teacher training, and to explore the direction of the good economic education to be demanded at the age of globalization and knowledge-based economy. To achieve the purpose of this study, the survey of the economic recognition and awareness of economic teachers was implemented through the four areas, that is, the content of the economic curriculum to complete in the college course and training program, the content of the outstanding questions of our economy at the age of globalization and knowledge-based economy, the content of information literacy at the age of knowledge-based society, and the content of economy literacy at the age of globalization. These four areas was investigated through survey as the subjects of the economic teachers of elementary, middle, and high school.

방광 소세포암:1예 보고

허정남,김용수,조온구,고병희,임현철,함창곡 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

Small cell carcinoma(also known as oat cell carcinoma) of the urinary bladder is an extremely rare malignancy and is derived from neuroendocrine stem cells. It is usually biologically aggressive tumor with early vascular and muscle invasion, so it has poor prognosis. Radiological findings of small cell carcinoma are similar to other malignancies of urinary bladder, therefore it is impossible to distinguish small cell carcinoma from other malignancies. Pathologic study is an only useful method for differential diagnosis of bladder tumor. We report here the case of 74th years old woman presented with painless gross hematuria.