근위 경골과 골절의 수술적 치료에서 예후 인자

최의성,박경진 충북대학교 의과대학 충북대학교 의학연구소 1997 忠北醫大學術誌 Vol.7 No.2

경골과 골절로 치료받은 17예의 환자를 대상으로 골절의 유형, 치료 방법, 정복의 정도, 골이식의 방법 및 동반 손상의 유무 등을 중심으로 치료 결과를 분석하여 예후에 영향을 미치는 인자를 조사하고자 하였다. 경골 외과의 분리 또는 설상형 골절의 제 1형이 가장 많았으며, 13예에서 수술적 정복 및 내고정이 시행되었다. 88%의 환자에서 만족할 만한 결과를 얻었는데, 동반 손상은 수술적으로 치료되었고, 결과에는 큰 영향이 없는 것으로 생각되었다. 경골과 골절에서 예후에 가장 영향을 미치는 인자는 골절의 정복 정도인 것으로 생각되었으며, 정확의 방법이나 고정 기간은 크게 문제되지 않았다. 5mm 이상의 관절면 불일치는 불만족한 결과를 초래하였다. 골이식과 만족한 결과와는 상관 관계는 보이지 않았으나, 큰 골 결손이 있는 경우 골이식은 꼭 필요할 것으로 생각되었다. Seventeen patients with fractures of the tibial plateau were reviewed and assessed in terms of fracture type, treatment method, adequacy of reduction, type of bone graft, associated ligamentous and meniscal injury, and overall result in an attempt to define factors important in the prediction of outcome. Cleavage or wedge-type fractures of lateral condylar plateau(type I) were the most common(29%). Thirteen of the 17 fractures were treated by open reduction and internal fixation, and three were treated by closed methods. Overall, 88% of the patients had a satisfactory result. Ligamentous and meniscal injuries were treated surgically and did not influence the final outcome. The single most important factor in predicting outcome in a patient with a tibial plateau fracture was the adequacy of reduction. The method of achieving the reduction and the length of the immobilization period of the knee were not as crucial. A residual step of greater than 5mm on the weight-bearing area was universally associated with an unsatisfactory result. Even there was no correlations between the satisfactory result with bone graft, bone graft to the large bone defect of tibial plateau fracture is seemed mandatory.

두부규격방사선사진에서 정상 sella turcica의 형태 및 크기에 관한 연구

최욱진,황의환,이상래 대한구강악안면방사선학회 2001 Imaging Science in Dentistry Vol.31 No.1

Purpose : To investigate the shape and size of normal sella turcica on cephalometric radiograms. Materials and Methods : Cephalometric radiograms of 200 orthodontic patients of age ranging 6-42 years were examined. All subjects were divided into 5 groups by age, the dimensional change of sella turcica was examined according to age, and the configurations of sella turcica floor, tuberculum sella, and anterior and posterior clinoid process were also observed. Results : The contours of sella turcica floor were flat type in 54% and concave type in 46%. The contours of tuberculum sella were right angle type in 55% and obtuse angle type in 44%; Acute angle type and plane type were very rare comprising 0.5%, 0.5% each. The configurations of anterior clinoid process were point type in 80% and round type In 20% of cases, and those of posterior clinoid processes were point type in 60% and round type in 40% of cases. The dimensional change of sella turcica according to age range had significantly positive linear trend to sella turcica length, height, and width until 25 years. After 26 years, no significant increase was found in sella turcica dimension. Especially, the sella turcica length had more proportional increase than that of sella turcica height and width. Conclusion : The results of this study revealed that the configuration of normal sella turcica was variable and the dimensional change of normal sella turcica had a linear tendency with age until 26 years.(Korean J Oral Maxillofac Radiol 2001;31:43-9)

악성 섬유성 조직구종에 관한 연구

최의환,오필교,김영진 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

Malignant fibrous histiocytoma(MFH) is relatively rare in the oro-maxillofacial region, particularly in the oral cavity. MFH usually arise in the extremities, the thigh being the most common site. The incidence of malignant fibrous histiocytoma in bones is rather low compared with that in soft tissues. MFH is predominant in the 40s and 50s. Histologically, the lesion are said to show high cellularity with fibrous stroma, cellular and unclear pleomorphism, and admixture of fibroblast-like spindle cells, which tend to be arranged in whorls or cartwheel or storiform patterns, rounded mononuclear cells and multinucleated giant cells. The cells frequently have abundant eosinophilic cytoplasm which has a foamy or vesicular appearance. Treatment consists of varying combinations of radiation therapy, chemotherapy, and surgery. We have observed a case of malignant fibrous histiocytoma occured in the right maxilla of 32-year-old woman.

Carboxymethylcellulose(CMC)를 이용한 수용성 섬유 제조 특성에 관한 연구

최영민,정의현,박진원,신재균,Toshio, Kajiuchi,Hong, Kyung Jin 한국공업화학회 2003 응용화학 Vol.7 No.1

The manufacturing characteristics of water soluble fiber were studied using carboxymethycellulose(CMC) prepared from viscose rayon. Manufactiring process of CMC consists of mercerization and etherification stages. Experimental conditions are NaOH and MCA concentration and stop of reaction process. The former two steps of manufacturing process were reduced to one step. The solubility of CMC in one step process was compared with former process.

하악과두에 발생된 골연골종의 증례보고

최욱진,황의환,이상래 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.2

The osteochondroma, also known as osteocartilagenous exostosis, is one of the most common benign tumors of the axial skeleton, but is rarely found in the facial bones. When present, the tumor is most often reported to affect the mandibular coronoid process. Osteochondroma of the mandibular condyle is extremely rare and may cause signs and symptoms like those seen in patients with temporomandibular joint dysfunction. Sometimes, differentiation between osteochondroma and condylar hyperplasia is not possible on histologic grounds alone, but the radiographic and intraoperative findings together are usually sufficient to establish a definite diagnosis, This report reviews the literature concerning osteochondroma, especially of the maxillofacial region, and describes a case of osteochon droma of the condyle. (Korean J Oral Maxillofac Radiol 2000; 30: 138-143)

CMC계 수용성 섬유의 물리적 강도향상 첨가제에 관한 연구

최영민,정의현,박진원,신재균,Kajiuchi, Toshio,Hong, Kyung jin 한국공업화학회 2003 응용화학 Vol.7 No.2

The aim of this research was to develope the additive for physical strength improvement of water soluble fiber(CMC) using viscose rayon. Experimental parameters were reaction time and concentration of MgSo₄. Firstly, solubility of carboxymethylcellulose(CMC) according to the addition of MgSO₄ was tested at room temperature with water. Secondly, through the examination of the FT-IR spectra, absorption band caused by hydroxyl group and carboxyl group was confirmed.

슬관절에 히야루론산 주입후 발생한 활막성 연골종증 : 증례 보고

최의성,김용민,김동수,손현철,박경진,조병기,배승환 충북대학교 의과대학 충북대학교 의학연구소 2009 忠北醫大學術誌 Vol.18 No.2

활막성 연골종증은 비교적 드문 양성 종양으로 관절내 활액막 결체조직의 양성 반응성 이형성에 의해 여러 개의 연골성 결절을 형성하고 이것이 관절내로 유리되어 유리체를 형성하는 질환으로 주로 슬관절에 발생한다. 활막성 연골종증의 정확한 발생 기전은 아직 밝혀지지 않았으나 외상, 감염 등이 원인으로 제시되고 있다. 저자들은 슬관절 내 히야루론산 주입후 발생한 슬관절내 활막성 연골종증을 1 례 경험하였으며, 관절경적 제거술을 통해 만족스런 결과를 얻었다. As a relatively rare benign tumor, synovial chondromatosis forms several cartilaginous nodules by the benign reactive metaplasia of synovial connective tissues within joints, which are loosed into the joints and cause a disease forming loose body mainly in knee joint. Accurate mechanism of synovial chondromatosis has not been clarified yet; however, trauma, infections and others have been suggested as its possible causes. The authors of this study experienced an example of a patient with synovial chondromatosis in knee joint occurred after the injection of hyaluronic acid in the joints and had a satisfactory outcome through the arthroscopic resection.

Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

Park*, Eui‐,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung‐,Sik,Kim, Yun‐,Jeong,Park, Young‐,Mee,Park, Eun‐,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

<P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

스포츠센터 소비자의 고객충성도에 영향을 미치는 요인에 관한 연구 : 서비스 품질과 서비스 가치를 중심으로 Centered on the quality and value of services

정의권,최영진,조현철 중앙대학교 스포츠과학연구소 2002 體育硏究 Vol.- No.17

This study centers on the quality and value of services perceived by consumers regarding factors that affect customer loyalties of sport center consumers. Study has been administered by a questionnaire survey of 200 male and female adult members of four sport centers in Seoul area. Following is the results: 1. Analyzing the relationship between demographic characteristics of sport center consumers and factors of their selection of those sport centers, there is significant difference in consumers' schooling and their family income. 2. Service quality perceived by sport center consumers appears to have a positive influence on service value. 3. Service value of sport center consumers appears to have a positive influence on customer loyalties. 4. Service quality perceived by sport center consumers appears to have a direct influence on customer loyalties. 5. Assessing the causal relationship between the service quality and value perceived by sport center consumers and customer loyalties, direct influence that the perceived service quality has on customer loyalties is stronger than indirect influence that mediated by service value.

스쿠알렌 합성 유전자를 도입한 형질전환 가시오가피

서진욱,정재훈,최용의,이학성,신차균 중앙대학교 유전공학연구소 2003 遺傳工學硏究論集 Vol.16 No.1

The enzyme, squalene synthase, represents a branch point in the isoprenoid pathway capable of diverting carbon flow specifically to the biosynthesis of phytosterol and Triterpenoid. Transgenic Eleutherococcus senticosus plants were prepared by introducing the genes for squalene synthase derived from Panax ginseng (PgSS1), hygromycin phosphotransferase (HPT) and green fluorescent protein (GFP) through Agrobacterium-mediated transformation. Establishment of transgenic plantlets were confirmed by the presence of PgSS1 and HPT bands in the genomic DNA preparation using a PCR method and a Southern blotting. In addition, expression of the introduced GFP DNA was confirmed by observing green fluorescence of GFP from the embroyos. In the in vitro analysis of the PgSS1 enzymatic activities the transgenic plants showed to have 1.5 to 3 times higher than wild type plant, indicating that the PgSS1 genes was well over-expressed in the transgenic plants. Especially the PgSS1 acivities of embroyogenic cell was 120 times higher than those of plantlet.