TLD 방사선 센서용 판독장치의 제작

우홍,강희동,최희동,이상윤,도시홍,김도성 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

IN VITRO STUDY ON APICAL SEAL AND SEM MORPHOLOGY IN CANALS FILLED WITH RESIN-BASED ROOT CANAL SEALER AND SELF-ETCHING PRIMER

강삼희,박동성,유현미,오태석 대한치과보존학회 2000 Restorative Dentistry & Endodontics Vol.25 No.4

Gutta-percha와 근관sealer를 사용한 근관 충전은 가장 많이 이용되고 성공률이 높은 방법이지만, 현재 사용되는 모든 근관sealer는 미세누출을 나타낸다. 따라서 더 효과적인 근관 폐쇄를 이루기 위한 재료 및 방법들이 연구되어 왔다. 이중 상아질 접착제는 근관 충전재와 함께 사용되어 미세누출을 감소시키지만, 근관 내에 사용하기에 술식이 복잡하고 기술이 요구된다. 본 연구의 목적은 gutta-percha와 레진계 근관 sealer로 충전한 근관에서 self-etching primer를 미리 도포한 경우와 도포하지 않은 경우의 치근단 미세누출을 비교하고, self-etching primer를 도포함에 있어 근관 내에 적용하는 방법에 따른 미세누출을 비교하는 것이다. 또한 근관sealer와 상아질 계면을 주사전자현미경으로 관찰하여, 이 결과를 미세 누출과 관련시켜보고자 하였다. 36개의 발거된 사람의 단근치에서 치관부를 절단, 제거하고 ProFile로 근관 형성한 후, 무작위로 선택하여 4개의 군으로 분류하였다. 1군에서는 주사기와 30게이지 주사 바늘로 self-etching primer를 근관 내에 적용하였고, 2군에서는 self-etching primer를 paper point에 적셔 근관 내에 적용하였다. 3군에서는 self-etching primer를 적용하지 않았다. 1, 2, 3군의 치아를 gutta-percha와 AH26 sealer를 사용하여 continuous wave 충전법으로 충전한 후 치근단공 주위 3mm를 제외한 치근면에 nail polish를 2회 도포하였고, 4군(음성 대조군)은 치근면 전체에 도포하였다. 1군과 2군에서 각각 2개의 치아는 주사전자현미경적 관찰을 위해 준비하였다. 모든 치아를 Methylene Blue 수용액에 48시간동안 침적, 수세한 후 치아 장축에 평행하게 양분하여, 10배의 실물확대현미경 하에서 치근단 색소 침투를 관찰하였다. Self-etching primer를 도포한 군과 도포하지않은 군 사이에는 평균 미세누출량에 유의한 차이가 없었다. 주사바늘로 적용한 군과 paper point로 적용한 군 사이에도 평균 미세누출량에 유의한 차이가 없었다. 상아질과 근관sealer계면의 주사전자현미경 관찰 결과 일부분에서 긴밀한 접착 관계를 나타내었고, 다른 부분에서는 간극을 나타내었다.

健脾益氣法의 腫瘍治療活用에 對한 硏究

姜硏伊,金聖勳,金東熙 대전대학교 한의학연구소 2002 한의학연구소 논문집 Vol.10 No.2

In review of "inviorating spleen an supplementing qi" of clinical and experimental studies on malignant tumor, we obtained the conclusions as follows 1. Asthenic splenic qi is an important factor in mutation, occurrence and development of tumor. 2. The anti-tumor mechanism of "invigorating spleen and supplementing qi" is improvement of immune suveillance, cntroling cell proliferating period and enhancing body metabolism. 3. "Invigorating spleen and supplementing qi" is often used with " nourishing kidney" or "expelling pathogen" for treating cnacer. 4. In experimental studies, "invigorating spleen and supplementing qi" has effects on inhibiting occurrence and development of tumor, protecting mutation, inhibiting recurrence and metastasis, immune activity, enhancing metabolism, promoting bone marrow hemopoietic cell proliferation, increasing anti-tumor effect and protecting normal cells. 5. In clinical studies, "invigorating spleen and supplementing qi" has effects on prolonging the survival period of cancer patients, improving clinical symptoms and quality of life of cancer patients, degrading the side effects of western therapie(operation, chemotherapy and radiotherapy). 6. "Invigorating spleen and supplementing qi" is an extensive discipline of syndrome differentiation used to inhibit occurence, development, recurrence and metastasis.

올인원 접착제의 미세누출에 관한 정량적 분석

강용희,신수일,신동훈 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.1

All-in-one adhesives were recently developed for reducing the techique sensitivity and chair time, but lots of concerns were made on bondability, longevity, and microleakage. The object of this study was to evaluate microleakage and marginal quality of all-in-one adhesives using electrochemical method and SEM analysis quantitatively. After making Class V cavities, they were bulk filled with Heliomolar(#A1) after surface treatment with three adhesives: Adper Prompt (Group A), One up Bond F (Group O), Xeno Ⅲ(Group 'X), Electrical con-ductivity(microamphere, ㎂) was checked two times: before and after cavity filling. Percentage of leaky margin was estimated from SEM image (× 1,000). The data were statistically analysed: ANOVA and Paired T test for electrical conductivity, Kruskal-Wallis and Mann-Whitney test for marginal quality, Spearman's rho test for checking of relationship between 2 methods the result were as follows: 1. There was no difference in microleakage between adhesive systems and every specimen showed some of microleakage after filling. 2. Microleakage was reduced about 70% with composite resin filling. 3. Marginal quality was the best in group A, decreasing among groups in the following order: group O, followed by group X. There were significant differences between group A and group X(p=0.015), and between group O and group X(p=0.019) 4. There was no relationship between the microleakage measured by electrochemical method and margin-al quality measured by SEM analysis. Within the results of this study, there was no difference in microleakage groups by electrical conductivity. However, significant difference in margin quality was seen among groups. It was believed teat these dissimilar results might be induced because of their own characteristics. Analysis of microleakage needs various methods for accuracy.

노인성 골다공증성 추체 압박골절 환자에 대한 경피적 척추성형술 후 치료 결과 및 합병증 : Treatment Efficacy and Complications

강동호,김기정,이철희,황수현,김은상,정진명 대한노인병학회 2002 대한노인병학회지 Vol.6 No.3

식물성 유지와 도라지 및 더덕의 첨가식이가 흰쥐의 뇌,고환 지방산 조성에 미치는 영향

강동희 진주여자전문대학 1994 論文集 Vol.17 No.-

This study was designed to observe the effects of the feeding platycodon grandiflorum, Codonopsis lanceolata, perilla oil and safflower oil on the fatty acid composition in brain and testis of dietary hypercholesterolmic rats. Experimemtal groups mixed with 5% cellulose +10% lard(lgroup, control group), 2% cholestyramine +10% lard (2group), 5% C.lanceolata +10% perilla oil (3group), 5% P.grandiflorum +10% perilla iol (4group), 5% C.lanceolata +10% safflower oil (5group) and 5% P.grandiflorum +10% safflower oil (6group)were administered to the male rats of the Sprague Dawley for 3weeks. The following shows the results obtained from this research. 1. In the fatty acid composition of brain lipids (total fatty acid, phospholipid), Eicosapentaenoic(EPA) and Docosahexaenoic acid(DHA) contents were more in the Polyunsaturated fatty acid(PUFA) and so they were major fatty acid, but showed little difference among the groups. 2. In the fatty acid composition of testis lipids (total fatty acid, phospholipid), PUFA showed high content, EPA and DHA were major fatty acid There was almost little difference among the groups.

천궁의 GABAА-Benzodiazepine 수용체 복합체와의 상호작용

강지현,이동웅,하정희 대한생물치료정신의학회 1997 생물치료정신의학 Vol.3 No.2

요약천궁(Cnidium Officinale)는 미나리과 다년생초본식물로서 대뇌 억제 및 진정 작용이 있다는 여러 문헌 등을 참고하여 볼 때 천궁은 항불안작용을 나타낼 가능성이 시사되었다. 이에 본 연구는 천궁을 사용하여 실험 동물에서 천궁의 항불안 작용을 검색하고 그 작용기전의 일부를 밝히고자 천궁을 극성 및 비극성 용매로 추출하여 분획을 만들고 이들 분획의 GABA-benzodiazepine 수용체 복합체 결합반응에 미치는 영향을 관찰하고자 하였다. 실험 결과 천궁 표준추출물 경구투여는 생쥐의 elevated plus maze 검사에서 그 효과는 diazepam 1 mg/kg 투여 후 실시한 elevated plus maze 검사 결과보다 낮았으나, 개방통로에로의 진입회수 및 개방통로에서의 체류시간을 증가시킴으로써 불안해소작용을 나타내었다. 또 천궁의 표준추출물은 benzodiazepine 수용체 길항제인 [3H]Ro15-1788 결합을 억제함으로써 수용체 활성물질의 존재 가능성이 관찰되었다. 이러한 행동검사상의 불안해소작용 및 benzodiazepine 수용체 활성도를 나타내는 구성성분을 추적하고자 천궁의 표준추출물의 분획화를 실시하였는데, 이를 통하여 얻은 각 분획들을 사용하여 수용체 활성도를 검색한 결과, 모든 분획에서 활성도를 나타내었으나 그 중 chloroform분획의 활성도가 crude한 추출물인 methanol 추출물이나 다른분획에 비하여 가장 높은 활성도를 나타냄을 관찰하였다.천궁의 chloroform분획은 [3H]flunitrazepam의 흰쥐대뇌피질조직에 있는 benzodiazepine 수용체에 대한 결합반응을 억제시켰으며, 이러한 억제도는 GABA 및 chloride 존재에 의해 더욱 항진되는 positive GABA shift 현상이 관찰되었다. 이상의 결과를 종합해볼 때, 천궁의 chloroform분획내에는 benzodiazepine 수용체에 대해 효현제 활성을 지니는 물질이 있음을 추측할 수 있으며, 이는 천궁의 항불안작용의 중요한 한 기전으로 생각된다. C. Officinale is a medicinal plant which has been known to have anxiolytic and sedative activity. A survey of the relevant literature has indicated that the putative anxiolytic activity of C. Officinale has not been scientifically investigated. Therefore, the present study was designed to assess anxiolytic property and interaction with benzodiazepine receptor of C. Officinale. The putative anxiolytic activity of methanol extract of C. Officinale was performed in mice using an elevated plus maze paradigm. Chronic oral administration of C. Officinale showed anxiolytic action in mice. The interaction of C. Officinale with benzodiazepine receptor was investigated using rat cortices. Methanol extract of C. Officinale inhibited the binding of [3H] Ro 15-1788, a selective benzodiazepine receptor antagonist to benzodiazepine receptor of rat cortices. Chlorform fraction of methanol extract showed higher binding activity to benzodiazepine receptor than crude extract by methanol. GABA significantly enhanced the potency of C. Officinale in inhibiting [3H] flunitrazepam, a selective benzodiazepine receptor agonist, binding to benzodiazepine receptor. From these findings, it can be concluded that substance or substances with neurochemical properties characteristic of a benzodiazepine receptor agonist may contribute to the anxiolytic property of C. Officinale.

생물막여과공정에 의한 고도정수처리시스템 구성에 관한 연구

강용태,양희천,김화석,김경동 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.2

This study is to evaluate the characteristics of submerged biofilter process as pretreatment of raw water and alternative advanced water treatment system(AAWTS) composed with bioflitration, post-ozonation and GAC for Nakdong River by comparison of existing advanced water treatment system(EAWS), composed with pre-ozonation, flocculation, sedimentation, sand filtration, post-ozonation and GAC. In the biofiltration process, the removal of turbidity, color, KMnO₄consumption, NH₃-N and UV254 reached 98%, 95%, 70%, 72%, 79% respectively. The stable removal efficiency was obtained by the direct biofiltration after coagulant injection thought the influent was a muddy and highly polluted. The removal efficiency of the alternative advanced water treatment(AAWTS) using biofiltration process for turbidity, color, KMnO₄consumption, NH₃-N and UV254 was reached 98.5%, 98%, 82%, 90%, 92% respectively. It is equivalent to the removal efficiency of existing advanced water treatment system(EAWTS) though the demanded area and coagulant of the alternative advanced water treatment system using biofiltration process was decreased about 60% and 70% respectively.

노인의 생활체육 참가와 여가만족 관계 연구

강관희,서동균 한국스포츠리서치 2001 한국 스포츠 리서치 Vol.12 No.4

The purpose of this study is to research into the influence of the old-aged-man's socio-economic variables and the characteristics of their participation in sport for all on their leisure satisfaction, and the influence of their socio-economic variables on the characteristics of their participation in sport for all, and thereby to provide some basic data for the activation of sport for all as leisure and the formation of the old-aged-man's proper leisure activity. For the achievement of such a study, data was collected through some questionnaires from 300 old people whose age is more than 60. And the collected data was statically processed through SPSS/WIN7.5, and with frequency and % calculated, One-way ANOVA were done. Result are as follows: First, it appeared that socio-economical characteristics educational background, age, method to provide living expenses, living together with husband or not - have a significant relation with their leisure satisfaction. Second, it appeared that the questioning items concerning the characteristics of participation in sport for all - the frequency of participation, the time of participation, factor influencing sport participation, and persons wishing to participate in sport for all - have a significant relation with leisure satisfaction.

紅蔘複合方의 補肝作用에 對한 實驗的 硏究(1)

姜彰熙,金聖勳,최봉균,金東熙 대전대학교 한의학연구소 2000 혜화의학회지 Vol.9 No.1

For the evalution of protective effect on hepatic damage by Korean red ginseng mixed formula, we used GR(Korean red ginseng), GRF-A(Korean red ginseng-mixed formula) as a materials. The study was performed on protective effect against hepatic damage induced by CCl_4. GRF-A significantly protected ethanol induced-liver damage by lowering ALT and ALP and fatty degenertion in liver tissue.