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과산화수소 증기를 이용한 다양한 쿠폰 표면의 Geobacillus Stearothermophilus 아포 제독조건
김상훈,정경화,김세계,채영규,김윤기,황현철,김민철,박명규,류삼곤,Kim, Sang Hoon,Jung, Kyoung Hwa,Kim, Se Kye,Chai, Young Gyu,Kim, Yun Ki,Hwang, Hyun Chul,Kim, Min Cheol,Park, Myung Kyu,Ryu, Sam Gon 한국군사과학기술학회 2013 한국군사과학기술학회지 Vol.16 No.4
Biological decontamination means the removal of microorganisms from the inanimate object such as building or equipment. In this study, hydrogen peroxide vapor efficacy test using VHP 1000ED system(Steris LifeSciences) were conducted for G. stearothermophilus spore with agent materials(aluminum, stainless steel, poly-carbonate, viton, silicone, kapton and glass). Total recovered spores exposed to hydrogen peroxide vapor(1.0 g/min) during 7, 15, 30, 60 min were calculated. As a result, all agent materials were totally decontaminated within 60 min at 1.0 g/min concentration with 35% hydrogen peroxide vapor. Finally, we could confirmed that hydrogen peroxide vapor possess sporicidal capacity of G. stearothermophilus and found the optimum decontamination conditions with VHP1000ED system.
김상훈,김세계,정경화,윤성녀,김윤기,김민철,류삼곤,이해완,채영규,Kim, Sang Hoon,Kim, Se Kye,Jung, Kyoung Hwa,Yoon, Sung Nyo,Kim, Yun Ki,Kim, Min Cheol,Ryu, Sam Gon,Lee, Hae Wan,Chai, Young Gyu 한국군사과학기술학회 2015 한국군사과학기술학회지 Vol.18 No.4
Decontamination of biological agents utilizes hydrogen peroxide($H_2O_2$) for its effectiveness and safeness. Bacillus anthracis is a major target for $H_2O_2$ decontamination. To assess the effect of $H_2O_2$ on B. anthracis and identify biomarkers for decontamination, whole transcriptomic profiling of $H_2O_2$-treated B. anthracis was performed. Here we identified deregulation in stress response genes, transcription factors and cellular homeostasis genes. We also found that expression of antisense RNAs increased in B. anthracis during decontamination. We postulate that B. anthracis prioritizes survival and adaptation in response to $H_2O_2$ treatment by changing its gene expression pattern.
슬관절 전치환술에서 후방 안정 임플란트의 오정렬이 경골 기둥에 미치는 영향
김상훈,안옥균,배대경,김윤혁,김경수,이순걸,Kim, Sang-Hoon,Ahn, Ok-Kyun,Bae, Dae-Kyung,Kim, Yoon-Hyuk,Kim, Kyung-Soo,Lee, Soon-Gul 대한의용생체공학회 2007 의공학회지 Vol.28 No.1
Recently, it has been reported that the posterior stabilized implant, which is clinically used for the total knee replacement (TKR), may have failure risk such as wear or fracture by the contact pressure and stress on the tibial post. The purpose of this study is to investigate the influence of the mal alignment of the posterior stabilized implant on the tibial post by estimating the distributions of contact pressure and von-Mises stress on a tibial post and to analyze the failure risk of the tibial post. Finite element models of a knee joint and an implant were developed from 1mm slices of CT images and 3D CAD software, respectively. The contact pressure and the von-Mises stress applying on the implant were analyzed by the finite element analysis in the neutral alignment as well as the 8 malalignment cases (3 and 5 degrees of valgus and varus angulations, and 2 and 4 degrees of anterior and posterior tilts). Loading condition at the 40% of one whole gait cycle such as 2000N of compressive load, 25N of anterior-posterior load, and 6.5Nm of torque was applied to the TKR models. Both the maximum contact pressure and the maximum von-Mises stress were concentrated on the anterior-medial region of the tibial post regardless of the malalignment, and their magnitudes increased as the degree of the malalignment increased. From present result, it is shown that the malalignment of the implant can influence on the failure risk of the tibial post.
김상훈,Kim, Sang-Hun 환경보전협회 2014 환경정보 Vol.412 No.-
인간의 생물 서식지 파괴, 환경오염, 외래종 도입 등은 지구 곳곳에서 생물종의 멸종을 야기하며 생물다양성에 큰 위협이 되고 있다. 이러한 상황이 지속되면 생태계 자체의 파괴는 물론이고, 궁극적으로 인간의 생존 기반을 위협하게 된다. 국제사회는 생물다양성의 보전과 지속 가능한 이용을 위해 올 9월 대한민국에 모인다.
2급 치근이개부 치료 시 흡수성 차폐막, 동종골 이식 및 혈소판 농축 혈장의 골 재생 효과에 대한 디지털 공제술의 정량적 분석
김상훈,임성빈,정진형,Kim, Sang-Hoon,Lim, Sung-Bin,Chung, Chin-Hyung 대한치주과학회 2002 Journal of Periodontal & Implant Science Vol.32 No.1
The purpose of this study was to evaluate effect of platelet rich plasma on the treatment of Grade II furcation involvement, with Demineralized Freeze-Dried Bone(Dembone(R)) and bioabsorable membrane(BioMesh(R)) in humans by digital subtraction radiography. 12 teeth(control group) were treated with Demineralized Freeze-Dried Bone(Dembone(R)) and bioabsorable membrane(BioMesh(R)), and 12 teeth(test group) were treated with Demineralized Freeze-Dried Bone(Dembone(R)), bioabsorable membrane(BioMesh(R)) and Platelet Rich Plasma. The change of bone density was assessed by digital subtraction radiography in this study. The change of mineral content by as much as 5%(vol) could be perceived in the subtracted images. The change of mineral content was assessed in the method that two radiographs are put into computer program to be overlapped and the previous image is subtracted by the later one. Both groups were statistically analyzed by Wilcoxon signed Ranks Test and Mann-whitney Test using SPSS program (5% significance level). The results were as follows: 1. In test group, the radiopacity in 3 months after surgery were significantly increased than 1 month after surgery(p<0.05). However. there were no significant difference between 1 month after surgery and 3 months after surgery in control group(p>0.05). 2. In test and control group, the radiopacity in 6 months after surgery were significantly increased than 1 month after surgery(p<0.05) 3. In test and control group, the radiopacity in 6 months after surgery were significantly increased than 3 months after surgery(p<0.05). 4. There were no significant difference between test group and control group at 1 month, 3 months after surgery, but radiopacity in test group were significantly increased than control group at 6 months after surgery(p<0.05). In conclusion, Platelet Rich Plasma can enhance bone density.