한국 국립공원 산림생태계의 수목 탄소저장량 평가

이상진,박홍철,박관수,김현숙,이창민,김진원,심규원,최승운,Lee, Sang-Jin,Park, Hong-Chul,Park, Gwan-Soo,Kim, Hyoun-Sook,Lee, Chang-Min,Kim, Jin-Won,Sim, Gyu-Won,Choi, Seung-Woon 한국환경복원기술학회 2022 한국환경복원기술학회지 Vol.25 No.3

The purpose of this study is to quantitatively evaluate the amount of carbon storage for trees in forest ecosystem to support the foundation for carbon neutrality implementation in Korea National Park. It targeted 22 national parks designated and managed as national parks in Korea, and conducted research on forest trees in the terrestrial ecosystem among various natural and ecological carbon sink. The survey and analysis method followed the IPCC guidelines and the National Greenhouse Gas Inventory in Korea. The amount of tree carbon storage in the forest ecosystem of Korea National Park was confirmed to be about 218,505 thousand CO₂-ton and the amount of carbon storage per unit area was 570.8 CO₂-ton per hectare. Compared to 299.7 CO₂-ton per hectare, the average carbon storage per unit area of the entire Korean forest, it was found that about twice as much carbon was stored when assuming the same area. In other words, it means that the tree carbon storage function of the national park is about twice as high as that of the average tree carbon storage function of entire Korean forest. It has great implications in Korea National Park not only provides biodiversity promotion and exploration services as a national protected area, but also performs excellent functions as a carbon sink.

포도당과 이소프로테레놀에 의한 시상하부의 소마토스타틴 분비가 갑상선자극호르몬방출호르몬에 의한 갑상선자극호르몬에 미치는 효과

박철영,양인명,오승준,김덕윤,우정택,김성운,김진우,김영설,최영길 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4·5

가성 종양으로 보인 신경베체트병 -임상 및 병리적 연관 비교-

박운규,김승현,김주한,김명호 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

당뇨병성 다발성 신경병증에 대한 Thioctic acid의 유효성 및 안정성에 관한 연구

박철영,김영설,오승준,우정택,김성운,양인명,김진우,최영길 대한당뇨병학회 2001 임상당뇨병 Vol.2 No.1

연구배경: 당뇨병성 신경병증은 당뇨병 환자에서 흔히 나타나는 합병증으로서 임상 증상은 가볍거나 없을 수도 있지만 많은 경우에 통증, 작열감, 이감각증이나 무감각증 등의 증상을 동반하지만, 이에 대한 명확한 기전이나 뚜렷한 치료방법이 없었다. 최근에 신경세포내 산화성 스트레스의 증가로 신경세포의 손상이 발생된다는 기전이 주목을 받으면서, 당뇨병성 신경병증 환자에게 항산화제인 thiotic acid를 사용하여 좋은 효과를 관찰한 논문들이 발표되었다. 이에 저자들은 한국의 당뇨병성 다발성 신경병증 환자에서 thiotic acid를 경구 투여 후에 신경병증에 의한 효과 및 안정성을 평가하였다. 방법: 모든 대상 환자에게 Thioctic acid 600㎎ 을 1일 1회 아침 식전 30분에 8주간 투여하여 당뇨병성 다발성 신경병증에 대한 TSS의 개선여부에 대한 임상적 유효성 및 이상반응, 내약성, 실험실적 지표의 변화를 통한 안정성을 관찰하였다. 결과: 치료시작 전에 관찰한 환자가 호소하는 증상은 통증이 가장 많았으며 무감각, 작열감, 이상감각 순의 빈도를 보였다. 통증, 작열감, 이감각증, 무감각증의 평균 TSS는 1차 방문시 5.8± 1.8, 2차방문시는 4.4±1.7, 3차 방문시는 3.1±1.1로 사용기판에 따라 통계학적으로 유의한 증상의 호전이 있었다. 또한 TSS의 개선 뿐만 아니라 통증, 작열감, 이감각증 및 무감각증 각각의 증상도 치료전과 치료 4주 후 및 치료 8주 후를 비교했을 때 통계학적으로 유의한 증상의 호전이 있었다. TSS가 1차 방문 시와 비교했을 때 3차 방문시에 30% 이상 개선되었을 때(1차 방문시에 TSS 4인 환자는 2점 이상 개선되었을때) 임상적으로 의미가 있는 반응으로 간주하고 계산한 반응률은 71.3%였다. 결론: 당뇨병성 다발성 신경병중 환자에 대해 항 산화제인 thioctic acid 600㎎ 경구 투여요법은 당뇨병성 신경병증의 증상완화에 유용하며, 안전한 것으로 사료된다. Background: The study was peformed to evaluate the efficacy and safety of oral treatment with the antioxidant α-lipoic acid (Thioctcid??) in diabetic patients with peripheral polyneuropathy. Methods: Thioctacid?? 600㎎ was orally administered once a day for 8 weeks in 61 diabetic patients with peripheral polyneuropathy. Neuropathic symptom(pain, burning, paresthesia, and numbness) were scored before, and of 4 and 8 weeks after treatment. In addition, neuropathy by the physician and patients at the end of treatment. The primary endpoint was the response role after 8 weeks treatment, defined as an improvement in the total symptom score of at least more than 30%. Results: Efficacy was evaluated among forty-four patients who had completely the study according to the protocol and safety was evaluated among all of 61 patients who had taken the study medication. The response rate after 8 weeks was 77.3%. The total symptom score was significantly decreased of 4-week, and further decreased of 8-week. All the individual scores for neuropathic symptom were also significantly reduced of 4-week and further decreased at 8-week. Conclusion: These finding indicate that oral treatment with thioctacid?? at a dose of 600㎎/day for 8 weeks will improve peripheral polyneuropathy in diabetic patients, without causing any serious adverse events.

高級經營者精報시스템 計劃 및 設計方法論 分析

朴慶洙,金勝運 全北大學校 1992 論文集 Vol.34 No.-

Information systems are designed around information requirements or needs. However, most existing information systems do not have the capabilities required to support executives' information needs. Excecutive information systems are designed to gether, process, and displasy the information that help senior executives assess their organization's success. The successful implementation of EIS is dependent of efficient information system planning. But the correct and complete information requirements for effective EIS planning and design are frequently very difficult to obtain. In this paper, methodologies for EIS planning and design are analyzed and availability of a methodology is presented through the case study.

Rhizopus oryzae를 이용한 바이오 디젤 생산

박상무,홍승준,이기영,김동운 全南大學校 觸媒硏究所 2002 觸媒硏究 論文集 Vol.23 No.-

Biodiesel was produced from soybean oil and methanol using fermentation broth or lipase. Production yield was 62% and 53.5% with purified Rhizopus oryzae lipase and Rhizopus oryzae broth respectively. This yield of biodiesel was highest in case of water content of 20%

農業副産物을 이용한 廢水중의 Cr( Ⅵ) 및 Cd(Ⅱ)이온의 除去

朴勝祚,宋運坤 동아대학교 환경문제연구소 1986 硏究報告 Vol.9 No.1

This study was carried out in a batch and a continuous apparatus to removal Cr(Ⅵ) and Cd(Ⅱ) using formaldehyde -H₂SO₄ treated agricultural by-products as an adsorbents. Some results obtained are summerized as followings: 1. The best one of five adsorbents is Formaldehyde· H₂SO₄ treated Saw Dust in batch adsorption tests. 2. Equilibrium relations between adsorbents and adsorbates was concided in Freundlich equation.(0.15≤1/n≤0.47) 3. Adsorption rate of Formaldehyde· H₂SO₄ treated Saw Dust was not effected more or less by pH and adsorbed Formaldehyde· H₂SO₄ treated saw Dust showed desorption rate of about 80%. 4. Excellent conditions of a continuous adsorption apparatus are bed depth(15 ㎝), flew rate(255 ㎝/hr). 5. The adsorptive capacity of Formaldehyde· H₂SO₄ treated Saw Dust are 5.7㎎ Cr(Ⅵ)/FTSD g and 55㎎ Cd(Ⅱ)/FTSD g in a continuous adsorption tests.

전계발광소자를 위한 강유전체 박막의 제작 및 특성

배승춘,김정환,김호운,박성근,김기완 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

PLT and PLZT feroelectric thin films were fabricated on ITO substrate by rf magnetron sputtering. Pressure was 30mTorr, rf power was 180W and substrate temperature was varied from room temperature to 500℃. In this case, PLT had the highest dielectric constant of 120 at 500 ℃, oppositly PLZT had the highest dielectric constant of 312 at room temperature. I-V characteristics of PLZT film were shown that leakage current of PLZT film deposited at room temperature was below 3μA at 100V.

한국인 당뇨병 및 비당뇨병 환자에서의 뇌혈관 질환 유무에 따른 PAI-1 촉진자 유전자형과 인슐린저항성에 관한 연구

오승준,김영설,박철영,김덕윤,김성운,양인명,김진우,최영길,팽정령,정경천 대한비만학회 2000 The Korean journal of obesity Vol.9 No.2

연구배경 : 혈전현상을 특징으로 하는 질환에서는 Plasminogen activator inhibitor-1 (PAI-1) 이 높은 활성도를 보이는데, PAI-1 치는 당뇨병, 심근경색증, 비만 등에서 높다고 밝혀진 바 있다. 또한 당뇨병 환자들의 합병증의 주요한 병인은 죽상경화증으로 혈전현상이 특징인 질환에서 증가하는 PAI-1이 당뇨병 환자에서 높다. 목적 : 정상인에서의 PAI-1 유전자 촉진자의 유전자형의 분포 및 혈액농도를 관찰하고, 당뇨병 및 뇌혈관 질환 환자군에서의 PAI-1 유전자 촉진자 유전자형의 분포 및 혈액농도를 측정하여 정상인과 차이점을 알아본다. 당뇨병 환자군에서의 혈장 PAI-1 치와 인슐린 저항성, 전구 인슐린 등과의 상관관계를 살펴보고, 인슐린저항성과 대혈관질환의 지표로 사용될 수 있는지 알아보았다. 방법 : 대상으로는 정상인 76명, 제2형 당뇨병 환자 56명, 뇌혈관질환이 동반된 제2형 당뇨병 환자 48명, 뇌혈관질환 환자 51명을 선택하여, 환자의 혈액에서 인슐린, 공복시 혈당, 전구인슐린, 중성지방, 총콜레스테롤 및 기타 생화학 검사 및 이학적 검사를 시행하였다. 환자의 DNA를 채취하여 전사개시 -675bp를 포함하는 대립형질 특이 시발체를 사용하여 중합효소 연쇄 반응을 실시하여, 그 유전자형을 판독하였다. 결과 : 정상 대조군 76명 (46.4±11.1세), 2형 당뇨병 환자 56명 (58.3±12.6세), 뇌경색증 환자 51명 (63.1±13.2세) 대상으로 하였다. PAI-1 촉진자 유전자형의 (4G/4G, 4G/5G, 5G/5G)빈도는 정상 대조군이 각각 23.7%, 75.0%, 1.3%, 뇌경색 환자군이 19.6%, 66.7%, 13.7%, 뇌경색이 동반된 당뇨병 환자군이 33.3%, 58.3%, 8.3% 였다. (X2=12.6, p=0.05). 이러한 사실은 서구인에 비해 4G/4G, 5G/5G 동형 유전자형이 낮은 결과였다. 각 군별 혈장 PAI-1 농도는 정상 대조군 13.4, 1.8 ~ 65.2 ng/mL (중앙값 , 범위 ) 2형 당뇨병 환자군 14.4, 2.9 ~ 47.8 ng/mL, 뇌경색 환자군 21.9, 6.2 ~ 154.7 ng/mL , 뇌경색이 동반된 2형 당뇨병 환자군 28.8, 3.2 ~ 139.3 ng/mL 로 차이를 보였다 (p=0.000). 전체 대상에서 PAI-1 촉진자 부위의 유전자형에 따른 PAI-1 활성도와 항원 농도는 차이를 보이지 않았다. 그러나 PAI-1 활성도는 혈중 중성지방, 전구인슐린, 체질량지수와 독립적인 상관관계를 보였다 (p=0.000, p=0.000 and p=0.005). 결론 : 결론적으로 PAI-1 촉진자 부위의 유전자형은 뇌경색증의 지표는 아니며, PAI-1 활성도를 결정짓는 인자는 유전적 요인보다는 혈중 중성지방, 전구 인슐린, 체질량지수와 같은 대사적 요인으로 생각된다. Plasminogen activator inhibitor-1 (PAI-1) is known be related to insulin resistance and several components of the large vascular disease. Notably, the high frequencies of diseases such as coronary heart disease or stroke are related to type 2 diabetes complications. We studied to find out whether the PAI-1 promother genotype could be a marker for cerebral infarction in type 2 patients. Subject patients were; 56 type 2 diabetics (age 58.3±12.6), 51 patients with cerebral infarction (age 63.1±13.2), 48 type 2 diabetics with cerebral infarction (age 64.8±9.3) , and 76 healthy control (age 46.4±11.1). The 4G/5G genotype of PAI-1 promoter was evaluated by polymerase chain reaction and endonuclease digestion. PAI-1 promoter genotype frequency (4G/4G, 4G/5G, 5G/5G) was 23.7%, 75.0% and 1.3% in healthy control, 17.9%, 67.9% and 14.3% in type 2 diabetes patients, 19.6%, 66.7% and 13.7% in cerebral infarction patients, 33.3%, 58.3% and 8.3% in type 2 diabetics with cerebral infarction (X^2=12.6, p=0.05). This finding is lower in frequency of 5G/5G homozygote than that reported in Caucasians. The plasma PAI-1 concentrations according to the disease were 13.4, 1.8 ~ 65.2 ng/mL (median, range) for healthy control, 14.4, 2.9 ~ 47.8 ng/mL for type 2 diabetes, 21.9 6.2 ~ 154.7 ng/mL for cerebral infarction , and 28.8, 3.2 ~ 139.3 ng/mL, for cerebral infarction with type 2 diabetes (p=0.000). In the all subjects, PAI-1 concentration and activity of PAI-1 promoter genotype did not show any significant difference. However, the PAI-1 activity was independently associated with serum triglyceride level, plasma proinsulin and BMI (p=0.000, p=0.000 and p=0.005 respectively). We concluded that PAI-1 genotype is not a marker for the cerebral infarction ; however, the genotype is related to PAI-1 concentration , and therefore it seems to be that metabolic factors such as triglyceride level or plasma proinsulin or BMI are more in relations with determining the PAI-1 concentration than the genotype.

근관감염세균의 분포에 관한 연구

김승윤,최호영,박상혁,최기운 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.4

It has been documented that periodontopathic bacteria are also implicated in endodontic infections. 16S rDNA gene-directed PCR was to examine the prevalence of periodontopathic bacteria including Actinobacillus actinomycetemcomitans (Aa), Prevotella intermedia (Pi), Prevotella nigrescens (Pn), Porphyromonas gingivalis (Pg), Porphyromanas endodontalis (Pe), and Treponema denticola (Td) in the root canals of 36 endodontically infected teeth having apical lesions with or without clinical symptoms like pain, swelling, and fistula. 1. In 36 infected root canals, most frequently detected bacterial species was Pg (61.1%), followed by Td (52.8%) and Pe (38.9%). 2. Of 36 infected root canals, Aa was detected in 6 canals (16.7%) of the teeth, all of which showed clinical symptoms. 3. Of 36 infected root canals, Pi and Pn Were found in 4 (13.9%) and 5 (33.3%), respectively. Notably, prevalence of Pn in the symptomatic teeth was 50.0%. 4. One of black-pigmented anaerobic bacteria (BPB) including Pi, Pn, Pe, and Pg was detected in all of the teeth that showed pain or especially swelling but not fistula. It was, however, found that prevalence of BPB in the asymptomatic teeth or the teeth with fistula was only 40%. 5. Pe and Pg were detected in the teeth regradless of the presence or absence of symptoms. High prevalence of BPB in the symptomatic teeth but low in the asymptomatic teeth suggested that BPB may play an important role in the pathogenesis of periapical lesions.