Organic Solar Cells: Solution‐Processable Reduced Graphene Oxide as a Novel Alternative to PEDOT:PSS Hole Transport Layers for Highly Efficient and Stable Polymer Solar Cells (Adv. Mater. 42/2011)

Yun, Jin‐,Mun,Yeo, Jun‐,Seok,Kim, Juhwan,Jeong, Hyung‐,Gu,Kim, Dong‐,Yu,Noh, Yong‐,Jin,Kim, Seok‐,Soon,Ku, Bon‐,Cheol,Na, Seok‐,In WILEY‐VCH Verlag 2011 Advanced Materials Vol.23 No.42

<P>Solution‐processable reduced graphene oxide as a hole‐transporting layer for highly efficient and stable organic solar cells is reported on page 4923 by Dong‐Yu Kim, Seok‐In Na, and co‐workers. Introduction of a newly reduced graphene oxide by simple solution processing into solar cells dramatically raises the cell efficiency and cell life‐time. The results will allow full use of chemically reduced graphene and will advance the realization of carbon‐based printable optoelectronic devices. </P>

명태의 행동제어용 심전도 도출에 관한 연구

박용석,이창헌,이유철,서두옥 제주대학교 해양연구소 1997 해양자원연구소연구보고 Vol.21 No.-

In the walleye pollock. Theragra chalcogramma. which has a heart with a strong electromotive force, the ECGs were found to be recordable by electrodes placed in the water from fish's body. The day on the experiment, fish was operated on in order to install a leading-out bipolar electrode. This electrode was used for recording of the cardiosignal of the fish on a digital storage oscilloscope. The electrode was made from a fish book which was re-shaped according to the shaped of fish heart and body surface. This hook was then connected to the lead-code insulated with paint, and the connecting part was covered with paint. The pointed end was stripped off slightly for conduction of electricity and the another pointed edge was used for hooking the electrode into the chest cavity. QRS complex of the ECG was marked. The amplitude of QRS complex was about 0.1-lmV. This method enabled us to observe the heart beat rate of the walleye pollock under least disturbed state. Ordinary heart beat rate was not quite regular. Very slight stimulation was enough to bring about cardiac inhibition. which was also accompanied by a considerable reduction in the amplitude of the QRS. After rough treatment. such as sound stimulus or electric shock. the heart beat rate showed remarkable decrease. reaching a value a few times lower than the normal level.

상부 조기 위암 환자의 복강경하 상부 위절제술 3례 경험

조규석,김형철,박경규,이문수,송옥평,임철완,신웅진,주종우,유기원 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Background : The reported incidence of early gastric cancer located in the upper portion of the stomach has been increasing with the recent advances in its diagnosis and screening. Recently, we have successfully performed laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without pyloroplasty on three patients with early gastric carcinoma localized to the upper third of the stomach. We describe our modification of this procedure in this report. Method : After creating an surgical pneumoperitoneum, the stomach was mobilized using laparoscopic coagulating shears. Upper half of the greater curvature and three-quarters of the lesser curvature were then dissected along with regoinal D2 lymphadenectomy. This was followed by a 5 cm, longitudinal mini-laparotomy in the upper abdomen, and the construction of the exteriorized stomach with a gastric tube measuring 20 cm long and 4 cm wide. Reconstruction with an esophagogastrostomy was performed using a circular stapler. Result : No post-operative morbidity or mortality was observed in this small series of patients. The average operative time was 250 minutes (range 220-300 minutes), and the average blood loss was 150 ml (range 90-180 ml). The mean number of lymph nodes harvested during these laparoscopic proximal gastrectomies was 24 nodes (range 22-25 lymph nodes). The average postoperative hospital stays was 7.5 days (range 7-8 days). Conclusion : Our technique of laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without phloroplasty offers a minimally invasive technique with the potential of impoving the post-operative quality of life patients with an early-stage proximal gastric cancer.

대퇴동맥을 통한 경피적 관동맥 중재시술 환자의 천자부위 지혈을 위한 Angioseal^(�) 사용과 고식적 용수 압박법의 비교 : 전향적 연구

김용훈,권현철,김필호,안석진,유철웅,최진호,이상철,김준수,김덕경,전은석,이상훈,홍경표,박정의,서정돈 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 경피적 관동맥 중재술은 최근 양적 및 질적으로 급격한 발전을 보였지만 시술 시 천자부위의 혈관 합병증은 아직 해결해야 할 문제점이다. 저자들은 대퇴동맥을 통한 경피적 관동맥 중재술을 환자에게 천자부위 지혈을 위한 혈관폐쇄기구인 안지오실의 안전성과 유용성을 고식적인 용수 압박법과 비교 연구하고자 하였다. 방법 : 2002년 4월부터 2003년 5월 사이에 삼성서울병원 심장혈관센터에서 대퇴동맥을 통한 경피적 관동맥 중재술을 성공적으로 시행한 200명의 환자(안지오실 사용군: A군, 100명, 고식적 용수압박법 사용군 B군, 100명)를 대상으로 시술 후 주요 합병증 및 경한 합병증, 지혈 후 환자가 자리에 앉기까지의 시간, 보행개시 가능시간, 총 재원 기간과 시술 1주 후의 합병증을 전향적으로 조사하여 비교 연구하였다. 결론 : 두 군에서 연령, 성별, 기저질환, 심혈관 질환의 위험요소, 시술의 종류, 시술 중 사용한 헤파린의 양, clopidogrel의 양, ticlopidine의 양, 지혈 시 수축기와 확장기혈압, ACT (activated clotting time)는 차이가 없었다. A군이 B군에 비해 시술 후 자리에 앉기까지의 시간 (A군: 4.3±0.3시간, B군: 13.7±0.8시간, p=0.004) 및 보행개시까지의 시간(A군: 6.8±0.5시간, B군: 18.8±2.1시간, p=0.013)이 유의하게 짧았다. 시술 후 주요 합병증은 두군 모두에서 관찰되지 않았으며, 경한 합병증의 전체발생은 A군에서 유의하게 적었다(A군: 28명, B군: 19명, p=0.003). 반상출혈의 경우는 A군에서 유의하게 낮았지만(A군: 3명, B군: 12명, p=0.01), 혈종, 출혈의 발생은 두군간에 차이가 없었다. 총 재원기간에는 두 군간에 차이가 없었다(p=0.239). 시술 1주 후 경과관찰에서 주요합병증은 역시 두 군 모두에서 관찰되지 않았으며, 경한 합병증의 전체발생은 두 군에서 차이가 없었다(A군: 15명, B군: 13명 p=0.418), 반상출혈의 빈도는 차이가 없었지만 혈종의 발생은 A군에서 더 낮았다(A군: 2명, B군:6명, p=0.004). 두 군 모두에서 출혈은 발생하지 않았다. 결론 : 대퇴동맥을 통한 경피적 관동맥 중재술을 시행한 환자에서 안지오실의 사용은 고식적 용수 압박법에 비해 환자의 침상 안정시간을 줄여 조기 활동개시가 가능하게 하였으며 국소합병증의 위험도를 일부 낮추어, 시술에 따른 환자의 불편을 현저하게 감소시킬 수 있다고 할 수 있을 것으로 기대된다. Background : Although the number and the quality of percutaneous coronary intervention have been recently increased dramatically, the vascular complication at puncture site is still the major cause of patients' morbidity. We evaluated the safety and efficacy of newly of newly-developed collagen-based arterial closure device, Angioseal after transfemoral percuatenous coronary intervention. Methods : This study was designed as a prospective single center non-randomized comparative study. A total 200 patients undergoing transfemoral percutaneous coronary intervention were enrolled between April 2002 and May 2003. They were divided into two groups; Angioseal group (group A, n=100) and manual compression group (group B, n=100). The baseline clinical and angiographic characteristics were reviewed. The time to sit up, the time to ambulation, the duration of hospital stay, major and minor vascular puncture site complications were monitored. The patients were followed-up for 1 week after procedure by telephone. Results : The baseline clinical characteriwtics, clinical diagnosis, cardiocascular risk factors, typesof procedure, doses and numbers of anticoagulants were similar between two groups. The blood pressure and activated clotting time were also similar. The time to sit up (group A: 4.3±0.3 hours, group B: 13.7±0.8 hours, p=0.004) and the time to ambulation (group A: 6.8±0.5 hours, group B: 18.8±2.1 hours, p=0.013) were shorter in group A. No major vascular complications were noted. The incidence of hematoma and bleeding were not significantly different between two groups. The incidence of ecchymosis, however, was significantly lower in group A (group A:12%, group B: 3%, p=0.001) The duration of gospital stay was similar between groups. During 7 days of follow-up period incidence of hematoma was significantly lower in group A (p=0.004). Although the incidence of ecchymosis was not significantly different between two groups. Conclusion : The angioseal may be associated with earlier ambulation and less patients' morbidity with low incidence of local complication rate compared to manual compression after transfemoral percutaneous coronary intervention.

한국 소아에서 보행발달 과정의 삼차원 동작분석 특성

박창일,박은숙,김유철,신지철,조상현,박진석 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.6

Differentiation of selectively labeled peptides using solid-state nanopores

Yu, Jae-Seok,Hong, Seong Cheol,Wu, Sangwook,Kim, Hyun-Mi,Lee, Cheolju,Lee, Jun-Seok,Lee, Ji Eun,Kim, Ki-Bum The Royal Society of Chemistry 2019 Nanoscale Vol.11 No.5

<P>Determination of the amino acid sequence of a protein is critical for understanding various biological processes. Mass spectrometry has mainly been used for protein identification; however, there are limitations to its sensitivity when detecting low abundance proteins. In this study, we attempted to distinguish between three similar peptide sequences (∼40 amino acids, ∼5 kDa) that differed only by the location or number of cysteine residues with solid-state nanopores. The cysteine residues are located at one end, one at the center, and at both ends for each of the three peptides. We found that differentiation of the three types of peptides by nanopore signals was difficult. However, when the cysteine residue was labeled with a negatively charged molecule, Flamma® 496, the labeled peptides showed distinct signals for each peptide. Comparing the relative current blockades of labeled peptides with applied voltages, we found that the label was able to change peptide conformations and the resulting ionic current signals from the three labeled peptides were distinguished based on the relative current blockade, full width at half-maximum of the current blockade distribution, and single-molecule level peak shape analysis. Our results suggest that solid-state nanopores combined with a targeted labeling strategy could be used to obtain characteristic peptide signatures that could ultimately be used for protein identification.</P>

Difference in Serum Iron, Cardiac, and Biochemical Indices between Alcoholic and Non-alcoholic Fatty Liver

Cheol-Yu Kim(김철유),Seong-Min Moon(문성민),Kyung-Yae Hyun(현경예),Dae-Sik Kim(김대식),Seok-Cheol Choi(최석철) 한국생명과학회 2009 생명과학회지 Vol.19 No.2

비록 음주가 간손상을 일으키는 지방간의 원인이 되긴 하나 다른 인자들 역시 지방간의 원인이 된다. 우리는 알코올성 지방간(알코올군) 및 비알코올성 지방간 남성(비알코올군)에 있어 철 표지자, 심장표지자, 그리고 생화학적 표지자의 변화와 차이를 연구하였다. 알코올군이 비알코올군 보다 신체지수, 수축기 및 확장기 혈압, 좌우안압이 유의하게 더 높았다. 또한 혈색소 농도, 적혈구 용적률, 평균 적혈구 혈색소량, 평균 적혈구혈색소 농도, 단구 수 역시 알코올군이 비알코올군 보다 유의하게 더 높았다. 생화학적 지수인 alanine aminotransferase, γ-glutamyltranspeptidase, 총콜레스테롤, 중성지방, 저밀도콜레스테롤, 혈당, 크레아티닌, 요산 등도 알코올군이 비알코올군 보다 유의하게 높았고, 철 지수인 철, 총철결합능, 페리틴 농도 역시 알코올군이 의미있게 더 높았다. 이러한 결과들은 장기적인 알코올 기인성 지방간이 비음주 지방간에 비해 혈청 철농도, 심혈관 표지자, 그리고 생화학적 표지자들을 더 상승시키며, 이는 심혈관 질환 및 대사성 증후군과 같은 성인병에 노출될 가능성이 보다 높을 수 있음을 시사하고 있다. Although alcohol drinking may cause fatty liver to induce hepatocytic injury, other factors lead to it. We designed this study to investigate the differences in serum iron, cardiac, and biochemical indices in men with fatty liver and the difference between alcohol drinkers (Alcohol group) and non-drinkers (Non-alcohol group). The alcohol group had higher body indices than the non-alcohol group. Systolic and diastolic blood pressure (SBP and DBP), and right and left intraocular pressure in the alcohol group were higher than those in the non-alcohol group. Hemoglobin, hematocrit, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and monocyte counts were higher in the alcohol group than in the non-alcohol group. Alanine aminotransferase, γ-glutamyltranspeptidase, total cholesterol, triglyceride, low-density lipoprotein cholesterol, glucose, creatinine, uric acid, iron, total iron binding capacity, and ferritin levels in the alcohol group were greater than those in the non-alcohol group. The present data reveals that alcohol-induced fatty liver has more elevated level of iron indices than in non-alcohol fatty liver as well as biochemical and cardiac indices, indicating that alcohol-induced fatty liver may cause possibility of adult diseases including cardiovascular disease and metabolic syndrome.

[PB-0100] Functional Analysis of Heat-induced RING-type E3 Ligases in Sorghum: Expression Patterns, Subcellular Localizations and Interaction Partners

Yu Kyong Hu(Yu Kyong Hu),Hong-Ju Lee(Hong-Ju Lee),Jeong Ho Shin(Jeong Ho Shin),Sang Hun Kim(Sang Hun Kim),Min Seok Choi(Min Seok Choi),Hyeon Ung Seo(Hyeon Ung Seo),Cheol Seong Jang(Cheol Seong Jang),S 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

음핵에서 발생한 신경집종

유유숙 ( Yu Suk Yu ),권도영 ( Do Young Kwon ),박지민 ( Ji Min Park ),최석철 ( Seok Cheol Choi ),유상영 ( Sang Young Ryu ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.12

Schwannomas arise from schwann cells in the peripheral nerve sheath, without involving the nerve fibers. Schwannomas are benign, slow-growing tumors that infrequently recur and rarely undergo malignant change. Also schwannomas of the female genitalia are considered extremely rare. We report a case of schwannoma of the clitoris. A 76-year-old woman without neurofibromatosis presented with a 2.0 × 1.7 cm, painless mass of the clitoris. Simple surgical excision of the mass was undertaken, and final pathology revealed schwannoma of the clitoris. No evidence of local recurrence was noted after 1 year of follow-up.

그물망을 이용한 서리 저감 효과 구명

유석철(Seok cheol Yu),김유용(Yu yong Kim),임성윤(Seong yoon Lim),송호성(Ho sung Song) (사)한국생물환경조절학회 2020 생물환경조절학회지 Vol.29 No.4

본 연구에서는 서리의 피해 저감을 위하여 과수 무봉지 재배를 목적으로 사용하고 있는 그물망을 이용하고자, 서리의 양을 관측하는 장치를 대조구와 시험구에 설치하여 그 비교를 통해 서리 저감 효과를 구명하였다. 시험 결과 실제 서리가 관측된 날을 기준으로 시험구에서 37%에서 59%까지 저감 효과를 확인할 수 있었다. 또한 서리의 양을 자동으로 관측하는 장치를 개발하고 풍동실험을 통해 서리 측정 장치의 방풍함 높이를 30 cm로 결정하였다. 이러한 연구 결과는 그물망 설치함으로써 과수 개화기에 서리 피해를 저감할 수 있을 것으로 판단되며, 그물망의 농업적 이용에 대한 기초자료로 활용될 수 있을 것으로 기대된다. This study was carried out to investigate reduction of the frost damage using the mesh net used for the purpose of non-bagged cultivation. A device measuring the weight of frost was developed and installed in both the control and the experimental, and the effect of frost reduction was evaluated with their weights. As a result, weight of frost in the control was reduced from 37% to 59% with mesh net on the day the frost was observed. In addition, the device for automatically observing the amount of frost was developed and the height of the windbreak of the frost measuring device was determined to be 30 cm through wind tunnel experiment. The results of this study are expected to reduce frost damage during the flowering season of fruit trees by installing mesh net and it is expected to be used as basic data for agricultural use of mesh net.