특수형 방사성 동위원소 운반캡슐의 안정성 평가

이주찬,서기석,구정회,방경식,한현수,박성원 대한방사선 방어학회 2001 방사선방어학회지 Vol.26 No.1

특수형 방사성물질 운반캡슐은 국내외의 수송관련 법규에 규정된 기술기준을 만족하도록 설계, 제작되어야 한다. 본 연구의 목적은 하나로에서 생산된 192Ir 특수형 동위원소 운반캡슐의 건전성을 평가하는데 있다. 법규에서 규정된 낙하시험, 타격시험, 굽힘시헝 및 가열시험조건에 대한 안전성 시험을 수행하였으며, 각각의 시험 전후에 누설시험을 수행하였다. 또한, 안전성시험과 더불어 컴퓨터코드를 이용한 전산해석을 수행하여 안전성시험 전에 시험결과에 대한 예측자료로 활용되었다. 낙하시험 및 가열시험 결과 캡슐 표면에서 약간의 흠집과 변형이 발생하였으나, 각각의 시험에서 평가기준이 되는 캡슐의 손상이나 용융 등은 발생하지 않았다. 또한 각 시험 후 수행한 누설시험 결과 누설이 발생하지 않았다. 따라서 특수형 방사성물질 운반캡슐은 법규에서 규정하는 기술기준을 만족하도록 설계, 제작되었음이 입증되었다. All of sealing capsules to transport a special form radioactive material should be designed and fabricated in accordance with the design criteria prescribed in IAEA standards and domestic regulations. The objective of this study is to demonstrate the safety of a shipping capsule for 192Ir special form radioisotope which produceed in the HANARO. The safety tests were carried out for the impact, percussion, bending and heat test conditions. And leakage tests were carried out before and after the each test. Also, the safety analyses were performed using computer codes in order to verify the test results. The capsule showed slight scratches and deformation, and maintained its structural and thermal integrities in all tests without any severe damage or melting. It also met the allowable limits of leakage rate after earth test. Therefore, it has been verified that the capsule was designed and fabricated to meet all requirements for the special form.

잠재적 교육과정으로서의 한국어 교재 요소 분석 -세종한국어 교재를 중심으로-

권기현 ( Kwon Ki-hyon Seo ),서덕순 ( Deok-soon ) 경희대학교 인문학연구원 2018 인문학연구 Vol.0 No.37

본 연구의 목적은 외국인학생을 대상으로 한 한국어 교재에 반영된 잠재적 교육과정을 확인하는 데 있다. 잠재적 교육과정(hidden curriculum)은 교수자 또는 교육기관에서 가르치도록 명문화되거나 의도하지 않았지만 학습 과정을 통해 학습자가 습득하게 되는 내용으로 교재 집필자의 관점, 교재를 사용한 교수법, 교재의 표현방식 등을 통해 학습자들의 한국어 사용에 영향을 미치는 요소를 이르는 용어이다. 본 연구에서는 국외에 한국어 보급을 목적으로 한 범용 한국어 교재인 <세종한국어> 1~8을 대상으로 인종과 지역에 대한 편견, 외국인에 대한 타자화된 시선을 고찰하고 학문, 직업, 성별, 연령별 관점이 다루어지는 방식을 분석하였다. 연구 결과 교재의 내용은 다양한 대상에 대한 정보를 다루었음에도 불구하고 차별적 서술을 완전히 벗어나지 못하고 있음이 확인되었다. 예컨대 국가나 지역에 대한 차별적인 정보 서술이 특정 지역에 대한 선입견을 공고화하거나, 교재에 인용된 외국인 학습자들의 대화와 행동에 대한 묘사가 외국인에 대한 타자화된 시선을 부추기는 현상이 발견되었으며, 직업군의 묘사에서도 성별과 연령, 국적 등이 치우쳐 다양한 사회의 모습을 다룬다고 보기 어려운 경우가 있었다. 이러한 시각의 불균형성을 해소하기 위한 대안으로 교실 상황에서는 다양한 관점에서의 정보를 공유하거나 제시된 정보에 대한 토론 활동 등을 진행하는 방식을 제시해보았다. The purpose of this study is to identify the hidden curriculums reflected on Korean textbooks through the way of dealing with cultural elements in South Korea. The hidden curriculums are content elements that are not specified or intended to be taught by teachers or educational institutions but are learned by learners. The viewpoints of the authors in the process of writing textbooks also affect the learners' use of Korean. In this study, the prejudices about ethnicity and regions and eyes upon foreigners who became others in the general Korean textbooks < Sejong Korean > 1 ~ 8 were addressed and how sex and age are handled was identified through academic fields and career fields. Despite that information in the text books dealt with diverse subjects, it has not completely got out of discriminative descriptions. For instance, discriminative descriptions of information about countries or regions contribute to the consolidation of prejudices about certain regions. In addition, eyes upon foreigners who became others were identified through descriptions of foreign learners' words and behaviors in the textbooks, and descriptions of occupations, etc. could not be said to deal with diverse shapes of society because they were one-sided in sex, age, and nationality. In order to relieve the imbalance of eyes, measures to share information from diverse viewpoints or to conduct discussion activities on presented information in classroom situations were presented.

Statistical assessment for spatio-temporal water quality in Angkor, Cambodia

Ki, Seo Jin,Kang, Joo-Hyon,Lee, Young Geun,Lee, Yun Seok,Sthiannopkao, Suthipong,Kim, Joon Ha IWA Publishing 2009 Water Science & Technology Vol.59 No.11

<P>Comprehensive water quality monitoring was conducted to assess the water quality conditions and to determine the impact of urban infrastructure on ambient water quality in Angkor, Cambodia. During this study, surface water, groundwater, and sediment samples were collected for two distinctive seasons in 2006-2007 at 58 monitoring sites along and near the Siem Reap River, in Tole Sap Lake (TSL), and West Baray, the primary water resources in this region. To assess the seasonal and spatial variability of 27 water quality parameters, multivariate analysis of variance, hierarchical cluster analysis, and the Kruskal-Wallis test were conducted using the obtained data. Differences and relationships between the surface water and groundwater were also investigated using t-test and correlation analysis, respectively. The results of these tests showed that the bacterial indicators need special attention as the urban infrastructure of the downtown area caused increased levels of these bacterial indicators in both surface water and groundwater. However, for most parameters, though surface water showed strong seasonal variations, groundwater presented relatively stable conditions between seasons (p&gt;0.05) with site-specific geochemical conditions. Sediment quality illustrated that pollution levels of 10 trace metals were the highest in TSL because of its unique characteristic (river with backward flow), but did not reflect any potential enrichment from urban development. Overall, the results reveal that while the urban infrastructure in this region has not significantly affected most of the water quality parameters, bacteria and coliphages are still a main concern due to their contributions in widespread waterborne diseases. Thus, careful mitigation plans for reducing each pollutant source are needed in the Angkor area.</P>

Thebesian vein Combined with Apical Hypertrophic Cardiomyopathy

In Ki Moon,Dae-Chul Seo,Jee Wan Wee,Byoung Won Park,Min Su Hyon 순천향의학연구소 2013 Journal of Soonchunhyang Medical Science Vol.19 No.2

A 52-year-old woman presented with atypical chest pain. Coronary angiography demonstrated multiple microfistulae between left coronary artery and left ventricle (LV) cavity, extensive enough to produce an LV angiogram. This LV angiogram revealed apical hypertrophic cardiomyopathy (HCM) which was confirmed by echocardiography. Coronary steal phenomenon by coronary artery microfistulae and HCM might have a role for developing of angina in patient with apical HCM.

Lignans from the Fruits of Schizandra chinensis and Their Inhibitory Effects on Dopamine Content in PC12 Cells

Seon-Mi Seo,Hak-Ju Lee,Youngki Park,Myung Koo Lee,Jae-In Park,Ki-Hyon Paik 한국생약학회 2004 Natural Product Sciences Vol.10 No.3

Five lignans including gomisin N (1), wuweizisu C (2), gomisin L1 (3), (+)-deoxyschizandrin (4), and gomisin J (5) have been isolated from the fruits of Schizandra chinensis. The structures of the isolated compounds were elucidated by analyzing MS and NMR spectra. Effects of the compounds isolated in this study on the dopamine content in PC12 cells were investigated to evaluate their inhibitory effectiveness. The gomisin N, wuweizisu C, and gomisin J showed 25.4%, 39.8%, and 35.1%, respectively, inhibition effect on dopamine content in PC12 cells at the concentration of 50 mg/ml.

Results of Fertility preservation program: A single center cohort study

( Jung Ah Roh ),( Bo Hyon Yun ),( Jae Hoon Lee ),( Minkyoung Kim ),( Seok Kyo Seo ),( Sihyun Cho ),( Young Sik Choi ),( Byung Seok Lee ),( Jung Ah Roh ),( Bo Hyon Yun ),( Jae Hoon Lee ),( Minkyoung Ki 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

목적: The aim of the study was to review the experience of fertility preservation (FP) program in a single center and to evaluate efficacy of FP referral program. 방법: From January 2013 to January 2016, the patients who have concern for their fertility that were referred to FP program were included. The age of patients at the time of discussing fertility preservation was under 40 years old. Total 103 patients who have undergone fertility preservation program in Severance hospital, Yonsei University College of Medicine were included. Statistical analyses were performed using chi-square test, Mann Whitney U test, and Kruscal-Wallis test according to the variables. 결과: Total 63 patients have undergone either embryo or oocyte cryopreservation, performing 82 controlled ovarian hyperstimulation cycles. Breast cancer patients composed the most: 15 patients (53.6%), 16 cycles of embryo; 22 patients (62.86%), 22 cycles of oocyte cryopreservation. Otherwise, patients diagnosed sarcoma, gastrointestinal, gynecological, and hematologic malignancy have been done the cryopreservation. Total 92 patients have received gonadotropin releasing hormone agonist for FP purpose. As similar as embryo/oocyte cryopreservation, patients with breast cancer composed the most: 46 patients (50%). The first 6 months follow up with serum anti-Mullerian hormone showed 0.23ng/dL (<0.08-13.41) in patients with breast cancer, 0.61ng/dL (<0.08-2.98) in patients with hematologic malignancy. The FP referral program between breast cancer clinic and infertility clinic was set since January 2015, and comparing the referral rate and FP rate between and after the FP program, significant increase was shown. However, referral and FP rate were similar in other cancers during the same time. 결론: The effective FP program between oncology department and infertility clinic seems to increase the rate of referral and participating FP program. Those who are expected to receive treatment that might affect fertility, should discuss about the FP options.

원전 해체 콘크리트 폐기물의 감용/재활용 기술 소개

서은아,이호재,권기현,김도겸,Seo, Eun-A,Lee, Hojae,Kwon, Ki-Hyon,Kim, Do-Gyeum 한국건설순환자원학회 2021 한국건설순환자원학회지 Vol.16 No.3

일차성 쇼그렌증후군 환자에서 나타나는 자가항체와 선외증상의 양상

서수홍 ( Soo Hong Seo ),김현숙 ( Hyun Sook Kim ),곽승기 ( Seung Ki Kwok ),주지현 ( Ji Hyeon Ju ),김상현 ( Sang Hyon Kim ),윤종현 ( Chong Hyeon Yoon ),김호연 ( Ho Youn Kim ),박성환 ( Sung Hwan Park ) 대한류마티스학회 2007 대한류마티스학회지 Vol.14 No.1

Objective: To investigate the extraglandular manifestations and serological features of Korean patients with primary Sjogren`s syndrome (pSS). Methods: Clinical and laboratory data of 125 patients with pSS attending rheumatology clinic of Kangnam St. Mary`s hospital, with a mean follow-up period of 64.8 months, were assessed retrospectively. Results: Arthralgia was the most common extraglandular manifestation of pSS. Other extraglandular manifestations, such as myalgia, peripheral neuropathy, Raynaud`s phenomenon, and hypothyroidism were frequently presented, but lymphoma was rare manifestation in Korean patients with pSS. Some extraglandular manifestations of pSS were associated with hypocomplementemia and antibodies against Ro, and La, and antinuclear antibody. Conclusion: The clinical manifestations and extraglandular manifestations of Korean patients with pSS patients were similar to other studies except low prevalence of lymphoma. Positivity of anti-Ro/SS-A, anti-La/SS-B antibodies and hypocomplementemia were closely associated with extraglandular manifestations in patients with pSS.

원전 폐콘크리트의 방사성 폐기물 처분용 고화제로의 활용을 위한 고화체 특성 평가

서은아(Eun-A Seo),이호재(Ho-Jae Lee),권기현(Ki-Hyon Kwon),김도겸(Do-Gyeum Kim) 한국건설순환자원학회 2021 한국건설순환자원학회 논문집 Vol.9 No.4

이 연구에서는 원전 해체 콘크리트에서 분리된 폐콘크리트 미분말을 방사성 폐기물용 고화제로 재활용하기 위한 성능평가를 수행하였다. 원전 해체 콘크리트에서 분리된 폐콘크리트 미분말을 모사한 시료를 제작하였으며, 주요 변수는 결합재 종류와 제올라이트 혼입율이었다. 고화제 특성평가는 유동성과 압축강도 및 비방사성 세슘에 대한 침출 저항성을 수행하였다. 폐콘크리트 모사시료의 압축강도는 제올라이트 혼입율이 증가함에 따라 증가하였으며, 제올라이트가 5% 이상 혼입된 고화제는 인수기준 대비 1.4∼1.7배 높은 압축강도를 나타내었다. 모든 시험체의 세슘 침출지수는 6 이상으로 인수기준을 만족하였으며, SA의 침출지수는 OPC 대비 1.47∼1.63배 높게 나타났다. 특히, 제올라이트 5% 치환 고화제의 28일 이후 평균 침출지수는 9.15으로 OPC 대비 약 6.4% 향상되었으며, 전 기간 동안 안정적인 성능을 나타내어 제올라이트가 세슘이온에 대한 침출저항성 향상에 효과적임을 확인하였다. The purpose of this study is to evaluate the performance of a solidifying agent for recycling the fine powder separated from the nuclear power plant decommissioned concrete as a solidifying agent(SA) for radioactive waste. In order to evaluate the performance of the solidifying agent, a powder simulating the fine powder of waste concrete separated from the dismantled concrete of a nuclear power plant was produced, and the main variables were the type of binder and the replacement ratio of zeolite. The solidifying agent was evaluated for fluidity performance, compressive strength, and leaching resistance to non-radioactive cesium. The compressive strength of SA increased as the zeolite replacement ratio increased, and the SA containing 5% or more of zeolite showed a compressive strength that was 1.4 to 1.7 times higher than the acceptance criteria. The cesium leaching index of all specimens was 6 or higher, satisfying the acceptance criteria, and the leaching index of SA was 1.47∼1.63 times higher than that of OPC. In particular, the average leaching index after 28 days of the 5% zeolite-substituted solidifying agent was 9.15, which was improved by about 6.4% compared to OPC, and it was confirmed that the zeolite was effective in improving the leaching resistance to cesium ions by showing stable performance over the entire period.

Slide Session : OS-RES-06 ; Oncology : Two Consecutive Intrapleural Injection of Cisplatin for Complicated Malignant Pleural Effusion

( Yong Hoon Kim ),( Ki Hyon Seo ),( Ju Ok Na ),( Jae Sung Choi ),( Ho Sung Lee ),( Ji Won Ryou ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Chemical pleurodesis is usually not effective for MPE accompanied with atelectasis, loculation and pleural invasion which need another approaches. Recently intrapleural chemotherapy with cisplatin has not been recommanded fi rstly because of low yields and high recurrence of MPE. However, most trials of intrapleural cisplatin were done one time with low doses. We expected more than one intrapleural cisplatin injection with higher dose might be better for complicated MPE. Methods: Patients were enrolled from 1 July 2013 to 30 June 2014. Intrapleural cisplatin (50 mg) injections were done two times via chest tube at 24hr interval after complete drainage of PE. Following each injection, chest tube was clamped for 6hrs. If there was no shfting on decubitus x ray or daily amount of drainage reduced by < 30 ml, chest tube was removed. Between one and two weeks after injections, CT or decubitus view was taken to evaluate early response. Late response was determined monthly thereafter. CR: no residual PE or no shifting on CT/x ray. PR: presence of minimal PE (subpleural fl uid = 1 cm in width). Stable: decreased but more than minimal. Failure or Relapse: no decreased or more increased PE in 2wks or progression after early response. Results: 22 complicated MPE (11 atelectasis, 8 pleural invasion, 2 loculation and 1 refractory to previous pleurodesis) in 20 patients were included. Early responses showed 14 CR (63.6%) and 8 PR (36.4%) (100% RR). Mean duration of overall response was 101ds. Late response was determined in 19 MPEs. Two (10.5%) were relapsed at 42 and 281ds and 2 (10.5%) were changed to stable from early CR/PR. RR of late reponse was 78.9% (15/19). Conclusions: Two consecutive intrapleural injection of cisplatin was highly effective for complicated MPE in both early and late periods.