Changes in Plasma Prolactin and Growth Hormone Level and Visual Problem after Radiation Therapy of Pituitary Adenoma

Son, Ho Young,Kang, Joon Ki,Bahk, Yong Whee,Kwon, Hyoung Chul,Yoon, Sei Chul,Oh, Yoon Kyeong,Song, Jin Un CATHOLIC MEDICAL CENTER 1985 Bulletin of the Clinical Research Institute Vol.13 No.1

Twenty-four cases of pituitary adenoma, 13 males and 11 females with the age ranging from 11 to 65 years, received radiation therapy (RT) on the pituitary area with a 6 MV linear accelerator during past 25 months at the Division of Radiation Therapy, Kang-Nam St. Mary's Hospital, Catholic Medical College. Of 24 cases of RT, 20 were postoperative and 4 primary. To evaluate the effect of RT, we analyzed the alteration of the endocrinologic tests (prolactin, growth homme), neurologic abnormalities, major clinical symptoms, endocrinologic changes and improvement in visual problems after RT.

한국형 틸팅열차 운행 중 운전 모드에 따른 고조파 분석 및 평가에 관한 연구

강철(Chul Kang),임재찬(Jae-Chan Lim),허재선(Jae-Sun Huh),김재철(Jae-Chul Kim),이수길(Su-Gil Lee),한성호(Soung-Ho Han) 대한전기학회 2009 전기학회논문지 P Vol.58 No.4

Recently, the new Korean Tilting Train Express(TTX) which maintains a speed on the curve railway line is developed. Electric railways, including the TTX, have electrical problems that could bring about serious accidents. For such reasons, the electric railway's electrical problems, electrical harmonic and others, have been studied briskly. Thus, TTX's electrical problems also need leading studies because the new Korean TTX will operate earnestly in 2012. The results could be used hereafter diagnosis of it's components and train conditions. In the paper, electrical signals in TTX operation were measured to analyze electrical harmonic. In addition, after the electrical signals were measured to operating mode (coasting mode, acceleration mode and regenerative breaking mode) respectively in test section(Ho-nam line, Chung-buk line, Jung-ang line and Tae-baek line). The electrical harmonics considered operating modes triparted were analysed and evaluated.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

Effects of Herbal Extracts Used in Oriental Medicines on Heme Oxygenase-1 Expression

Jeong, Gil-Saeng,Oh, Seung-Hwan,Kang, Dae-Gill,Lee, Ho-Sub,Kim, Youn-Chul The Physiological Society of Korean Medicine and T 2006 동의생리병리학회지 Vol.20 No.5

Effects of twenty-three aqueous herbal extracts used in oriental medicines on heme oxygenase (HO)-1 expression were estimated in a mouse hippocampal cell line, HT22. HO-1 is one of the cytoprotective enzymes activated various stimuli, and Western blot analysis was used for evaluated HO-1 expression. Six aqueous extracts such as Rhei Rhizoma, Paeoniae Radix, Uncariae Ramulus et Uncus, Theae Folium, Prunellae Spica, and Coptidis Rhizoma significantly increased HO-1 expression in HT22 cells at the concentration of 300 ${\mu}$g/ml. In Addition, four aqueous extracts including Eucommiae Cortex, Moutan Cortex Radicis, Ginseng Radix Rubra, and Scutellariae Radix moderately increased HO-1 expression. These results would be usefulfor the isolation and identification of their neuroprotective principles.

Sauchinone Suppresses Pro-inflammatory Mediators by Inducing Heme Oxygenase-1 in RAW264.7 Macrophages

Li, Bin,Lee, Dong-Sung,Choi, Hyun-Gyu,Kim, Kyoung-Su,Kang, Dae-Gil,Lee, Ho-Sub,Jeong, Gil-Saeng,Kim, Youn-Chul Pharmaceutical Society of Japan 2011 BIOLOGICAL & PHARMACEUTICAL BULLETIN Vol.34 No.10

<P>Sauchinone, a biologically active lignan isolated from the roots of <I>Saururus chinensis</I> (L<SMALL>OUR</SMALL>.) B<SMALL>AILL</SMALL>. (Saururaceae), is reported to exert a variety of biological activities, such as hepatoprotective, anti-inflammatory actions and inhibitory effects on bone resorption. In this study, we investigated the effect of sauchinone in suppressing cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) expression, leading to a reduction in COX-2-derived prostaglandin E<SUB>2</SUB> (PGE<SUB>2</SUB>) and iNOS-derived nitric oxide (NO) production in lipopolysaccharide (LPS) stimulated RAW264.7 macrophages. Present study also demonstrates the effects of sauchinone in inducing heme oxygenase-1 (HO-1) expression and an increase in heme oxygenase (HO) activity in RAW264.7 macrophages. The effects of sauchinone on LPS-induced PGE<SUB>2</SUB>, NO, tumor necrosis factor-α (TNF-α) and interlukine-1β (IL-1β) production were partially reversed by the HO-1 inhibitor Tin protoporphyrin was also seen in this study. In addition, we found that treatment with extracellular signal-regulated kinase (ERK) inhibitor (PD98059) reduced sauchinone-induced HO-1 expression. Sauchinone also increased ERK phosphorylation. These results suggest that sauchinone inhibits pro-inflammatory mediators through expression of anti-inflammatory HO-1 <I>via</I> ERK pathway.</P>

마이크로 모빌리티 네트워크에서의 안전한 멀티캐스트

姜昊錫,沈永喆 弘益大學校 科學技術硏究所 2004 科學技術硏究論文集 Vol.15 No.-

To reduce the control message overhead due to frequent handoffs in mobile IP, micro-mobility protocols have been proposed. In this paper we present an approach for providing secure multicasting services in micro-mobility environments. We first introduce a multicast routing protocol in a micro-mobility environment and then present protocols to add security services to the bare multicasting. The proposed multicast routing protocol builds a shared multicast tree and does not assume any unicast micro-mobility protocols. The added security services include authentication, authorization, confidentiality, and integrity and are based on both symmetric and asymmetric cryptosystems. The security protocols also use key hierarchy mechanism in a paging area to efficiently handle frequent group membership changes and handoffs.

公園散策路 改設품에 關한 基礎硏究

강호철,윤인규 진주산업대학교 산업과학기술연구소 1996 산업과학기술연구소보 Vol.- No.3

산책로는 일반적으로 시공측량, 잡초제거, 장애목의 간벌/제근, 수림지의 수목 간벌, 지반조성, 비탈면고르기, 포장마무리 (원지반다짐/포장재) 등의 공정에 의하여 조성된다. 시공측략은 일반적으로 공사비에 포함되어 있으며, 잡초제거품은 조경공사에서 잔디밭의 잡초를 제거하는 품을 적용하고, 공사난이도에 따라 인력의 할증, 제초 기계경비 및 품은 별도 계상한다 산책로 개설과 관련된 벌채, 제근 공종은 벌채공사의 성격보다는 간벌공사이므로, 간벌 및 제근되는 수목의 규격 및 수량을 조사하여 간벌품을 적용하고, 소운반비를 계상해야 한다. 간벌공사는 국유림매각기준의 간벌품을 적용하고, 제근공사와 소운반은 건설표준품셈의 품을 적용한다. 수목 소운반은 산림청의 집재품에 앞서 건설표푼품셈의 인력운반품을 적용하다. 인력운반품의 산출시, 공원의 평균구매 및 평균거리를 산출하여 운반품에 할증율을 적용한다. 이러한 품을 적용하는 데 기준이 되는 수목의 재적 및 중량은 산림청의 재적 산출식에 준하여 산출한다. 산책로와 관련된 토공공사는 노상조성, 법면정리, 원지반 다짐 또는 포장 등의 세부공정으로 이루어진다. 노상정리는 산책로의 폭원을 확보하기 위한 공사로서, 품의 적용은 현장여건에 따라 인력투입 또는 장비투입을 결정한다. 법면정리공사에는 절토면 고르기, 성토면 고르기, 성토면 인력다지기 등의 세부 공정이 필요하다. 원지반 다짐은 도로의 평탄성 및 토사안정화를 위한 공정으로서, 산책로 예정로의 구배 및 폭원에 따라, 진동롤러 등을 선정하여 사용할 수 있다. 조경공사는 토목공사와는 달리 소규모이고, 건축공사처럼 소규모공사를 고려한 새분화된 건설품셈이 없는 실정이다. 이러한 연유로 조경공사는 소규모, 산발적인 공사임에도 불구하고, 비현실적인 토목공사 공사비를 산출하는 방법이 적용되고 있다. 조경공사용 건설품셈을 재정립하는 것이 가장 바람직하겠다. 그러나, 건설품셈 재정립에 앞서 조경공사를 공정별로 세분화시켜 누락되는 공정이 없도록 하는 것이 우선이다. 또한, 세부화된 공정에 적절한 건설품셈을 도출하여 공사비를 산출하고, 건설품셈에 명기되지 않은 공정에 대하여는 정부관련기관에서 적용하고 있는 품을 조사하여 적용가능성에 대하여 검토하는 과정도 필요하다. 본 연구는 공정의 세분화, 유사 품셈의 적용방법에 있어서 기초가 될 것이다. As the result of analysis on the practical process of construction a walk in natural park, it is consist of surveying, plucking out a weed, thinning, leveling the ground and the slope, paving. In the labor content of construcion a walk in natural park, because it is collectively not established by the Ministry of Construction , as it is called Standard Labor Content by the Ministry of Construction, each process of construction are applied to an appropriate content among the other ones with approval of the goverment.

고조파 분석을 이용한 고저항 지락사고 검출에 관한 연구

강승호,조성빈,김철환 成均館大學校 科學技術硏究所 1999 論文集 Vol.50 No.1

High Impedance Fault(HIF) is defined as fault that general overcurrent relay can not detect or interrupt. When HIF occurs in transmission line, arc with energized high voltage conductor is happened and results in fire hazard, equipment damage or personal threat. This paper proposed the HIF fault detection method using harmonic analysis and showed the arc model which can he implemented within Electromagnetic Transients Program(EMTP). Harmonic analysis is efficient and useful for the detection of HIF in power system because it shows good characteristics about odd harmonic components of current when HIF occurs.

높은 입체선택성을 나타내는 고리카보네이트의 친핵성 치환반응과 광학활성인 β-Hydroxy Ester의 합성

강석구,박동철,노호식,윤승현,홍덕표 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.1

The nucleophilic ring opening of the cyclic carbonates of optically active threo-2,3-dihydroxy esters afforded α-substituted β-hydroxy esters with highly regio- and stereoselectivity under mild conditions. The α-substituted β-hydroxy esters were transformed to β-hydroxy esters

『春香新說』과『懸吐漢文春香傳』의 作者와 創作年代

강재철,허호구 단국대학교 1998 論文集 Vol.32 No.-

A Study on the writer and story-writing date of Hanmoonchunhyanggeon is one of our major researches in classical as and important process of organizing Chunhyanggeon. so, I world like to render great academic advance in studying writers and story-writing date of two texts of Hanmoonchunhyanggeon which is diverse in opinions in academic circles. Conclusion of this paper are as follows ; The story-writing date of Chunhyangsinsul is 1864, and the writer is not Teo-lim Mok who is insisted by some scholars in academic circles but unidentified right now. And the first edition date of Heuntohanmooncunhyangeon is 1917, and Chul-Gin Wu who si recognized as a writer is regarded as an ordinary publisher. I believe these conclusions can devote much help in studying Chunhyanggeon and discussing aspects of Gookmoonchunhyanggeon and Hanmoonchunhyanggeon in the future.