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      • KCI등재

        Feasibility of Using a One-temperature Model for Determining Plasma’s Temperature by Measuring Its Refractive Index

        Yun-yun Chen,Fen-ping Cui,Fang Gu,Ying-ying Zhang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.11

        In this paper, the feasibility of using a one-temperature model to determine plasma’s temperatureby measuring its refractive index is studied based on the consideration that many plasma flow fieldsare not in local thermodynamic equilibrium (LTE). We compare the refractive indices between theone- and the two-temperature models of an arc plasma, in order to discuss the applicability ofthe one-temperature model in optical diagnosis. We found that the applicability is determined bythe pressure, the temperature ratio between electrons and heavy particles, the probe wavelength,and the chosen optical method’s refractive index measurement precision. Consequently, a commonmodel is deduced to describe the refractive index of plasma whether it be in LTE or not. In a word,this study is crucial to better apply optical methods based on measurements of the refractive indexto diagnose plasma flow fields.

      • Exercise and Cognitive Function: Advancing Evidence Synthesis with Umbrella Reviews

        Michael Chen, Chen-Sin Hung, Marius Brazaitis, Yun-Rui Yang, Chueh-Yin Chen, Yu-Kai Chang 아시아운동학회 2026 Physical Activity Vol.4 No.1

        OBJECTIVE Exercise is recognized as a promising intervention for enhancing cognitive function. This mini-review aims to highlight the role of exercise in promoting cognitive performance, with a particular emphasis on umbrella reviews as an innovative evidence synthesis approach in this field. METHODS This review narratively summarizes current evidence on the effects of acute and chronic exercise on cognitive function and emphasizes the methodology and application of selected umbrella reviews. RESULTS Three umbrella reviews show that exercise improves cognitive function across age and clinical groups. Acute exercise yields small-to-medium cognitive benefits across domains, unaffected by age, fitness, cognitive status, or exercise characteristics; Specific exercise modalities enhance cognitive function across MCI, dementia, Alzheimer’s, Parkinson’s, and post-stroke populations; and Exercise yields small cognitive benefits in depression, with a number needed to treat of 14.79. CONCLUSIONS Umbrella reviews suggest cognitive benefits of exercise across different populations and point to the potential value of culturally embedded approaches. Future studies may consider combining umbrella reviews with individual participant data analyses to refine the recommendations for cognitive health.

      • KCI등재

        Incorporating Mathematics into STEAM Project-based Learning Activity: A Pedagogical Model

        Hange Yun(Hange Yun),Qiaoping Zhang(Qiaoping Zhang),Yiru Chen(Yiru Chen),Wing Nam Chau(Wing Nam Chau) 대한수학교육학회 2024 수학교육학연구 Vol.34 No.4

        Mathematics is a crucial but often underestimated aspect of STEAM education. This study presents an innovative Project-Based Learning (PBL) approach to integrate mathematics into STEAM education in mathematics classrooms, focusing on 3D shapes for second-grade students in a Hong Kong primary school. The “Funny Zoetrope Project” aims to enhance students’ understanding of cylinder concepts through a seven-session program, including five mathematics and two visual arts classes. Enhanced by carefully crafted learning journals, this mathematics-focused activity encourages students to apply their mathematical knowledge in a wider context. Students participate in interdisciplinary learning by constructing a zoetrope, seamlessly blending their understanding of mathematics and visual arts. This study is a practical example of mathematics integration into STEAM education, providing educators with a useful model for effective STEAM pedagogy.

      • Association between Polymorphisms of Interleukin-17A and Interleukin-17F Genes and Silicosis Susceptibility in Chinese Han People

        Chen, Ying,Fan, Xue-Yun,Jin, Yu-Lan,Yao, San-Qiao,Yun, Xiang,Hua, Zheng-Bing,Shen, Fu-Hai Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

        Background: To explore the relationship between polymorphisms of interleukin17 (IL-17) gene(A-832G 7488A/G) and the susceptibility to silicosis, a risk factor for lung cancer. Materials and Methods: A total of 113 silicosis patients and 116 workers without silicosis were enrolled in the case-control study. IL-17A A-832G and IL-17F 7488A/G polymorphisms were evaluated by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: The frequencies of AA,GG and AG of IL-17A A-832G locus in the case and control groups were 46.9%, 8.0%, 45.1%, and 49.2%, 7.6%, 43.2%, respectively, with no significant differences (p>0.05).The GG genotype in the IL-17F (7488A/G) locus was not found. The frequencies of AA and GA of IL-17F 7488A/G locus in the case and control groups were 84.1%, 15.9% and 66.4%, 33.6%, respectively (p<0.05). Analysis of combined effects showed that the individuals with GG+AG genotype of IL-17A and GG+GA genotype of IL-17F are protected against silicosis (OR=0.469). Conclusions: IL-17F 7488A/G is associated with susceptibility to silicosis, and G allele may have a protective effect. No relationship was found between IL-17A gene polymorphisms at A-832G and silicosis.

      • KCI등재후보

        Traditional, complementary and integrative medicine for fatigue: A systematic review of randomized controlled trials

        Chen, Xiao-ying,Lu, Chun-li,Wang, Qian-yun,Pan, Xing-ru,Zhang, Yang-yang,Wang, Jia-le,Liao, Jun-Ya,Hu, Nai-chong,Wang, Chen-yang,Duan, Bing-jie,Liu, Xue-han,Jin, Xin-yan,Jennifer Hunter,Jian-ping Liu 한국한의학연구원 2024 Integrative Medicine Research Vol.13 No.2

        Background: Chronic fatigue is a predominant symptom of post COVID-19 condition, or long COVID. We aimed to evaluate the efficacy and safety of Traditional, Complementary and Integrative Medicine (TCIM) for fatigue. Methods: Ten English and Chinese language databases and grey literature were searched up to 12 April 2023 for randomized controlled trials (RCTs). Cochrane “Risk of bias” (RoB) tool was applied. Evidence certainty was assessed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Effect estimates were presented as risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI). Results: Thirteen RCTs with 1632 participants were included. One RCT showed that Bufei Huoxue herbal capsules reduced fatigue (n=129, MD -14.90, 95%CI -24.53 to -5.27), one RCT reported that Ludangshen herbal liquid lowered fatigue (n=184, MD -1.90, 95%CI -2.38 to -1.42), and the other one RCT shown that fatigue disappearance rate was higher with Ludangshen herbal liquid (n=184, RR 4.19, 95%CI 2.06 to 8.53). Compared to traditional Chinese medicine rehabilitation (TCM-rahab) alone, one RCT showed that fatigue symptoms were lower following Qingjin Yiqi granules plus TCM-rehab (n=388, MD -0.48, 95%CI -0.50 to -0.46). Due to concerns with RoB and/or imprecision, the certainty in this evidence was low to very low. No serious adverse events was reported. Conclusions: Limited evidence suggests that various TCIM interventions might reduce post COVID-19 fatigue. Larger, high quality RCTs of longer duration are required to confirm these preliminary findings. Protocol Registration: The protocol of this review has been registered at PROSPERO: CRD42022384136. Background: Chronic fatigue is a predominant symptom of post COVID-19 condition, or long COVID. We aimed to evaluate the efficacy and safety of Traditional, Complementary and Integrative Medicine (TCIM) for fatigue. Methods: Ten English and Chinese language databases and grey literature were searched up to 12 April 2023 for randomized controlled trials (RCTs). Cochrane “Risk of bias” (RoB) tool was applied. Evidence certainty was assessed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Effect estimates were presented as risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI). Results: Thirteen RCTs with 1632 participants were included. One RCT showed that Bufei Huoxue herbal capsules reduced fatigue (n=129, MD -14.90, 95%CI -24.53 to -5.27), one RCT reported that Ludangshen herbal liquid lowered fatigue (n=184, MD -1.90, 95%CI -2.38 to -1.42), and the other one RCT shown that fatigue disappearance rate was higher with Ludangshen herbal liquid (n=184, RR 4.19, 95%CI 2.06 to 8.53). Compared to traditional Chinese medicine rehabilitation (TCM-rahab) alone, one RCT showed that fatigue symptoms were lower following Qingjin Yiqi granules plus TCM-rehab (n=388, MD -0.48, 95%CI -0.50 to -0.46). Due to concerns with RoB and/or imprecision, the certainty in this evidence was low to very low. No serious adverse events was reported. Conclusions: Limited evidence suggests that various TCIM interventions might reduce post COVID-19 fatigue. Larger, high quality RCTs of longer duration are required to confirm these preliminary findings. Protocol Registration: The protocol of this review has been registered at PROSPERO: CRD42022384136.

      • KCI등재

        Association of the PPAR-γ Gene with Altered Glucose Levels and Psychosis Profile in Schizophrenia Patients Exposed to Antipsychotics

        Yun-Ru Liu,El-Wui Loh,Tsung-Ming Hu,Tsuo-Hung Lan,Hsien-Jane Chiu,Yung-Han Chang,Shuo-Fei Chen,Yen-Hsin Yu,Cheng-Chung Chen 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.2

        Objective Metabolic abnormalities, e.g., diabetes, are common among schizophrenia patients. Peroxisome proliferator activated receptor-γ (PPAR-γ) regulates glucose/lipid metabolisms, and schizophrenia like syndrome may be induced by actions involving retinoid X receptor-α/PPAR-γ heterodimers. We examined a possible role of the PPAR-γ gene in metabolic traits and psychosis profile in schizophrenia patients exposed to antipsychotics. Methods Single nucleotide polymorphisms (SNPs) of the PPAR-γ gene and a serial of metabolic traits were determined in 394 schizophrenia patients, among which 372 were rated with Positive and Negative Syndrome Scale (PANSS). Results SNP-10, -12, -18, -19, -20 and -26 were associated with glycated hemoglobin (HbA1c) whereas SNP-18, -19, -20 and -26 were associated with fasting plasma glucose (FPG). While SNP-23 was associated with triglycerides, no associations were identified between the other SNPs and lipids. Further haplotype analysis demonstrated an association between the PPAR-γ gene and psychosis profile. Conclusion Our study suggests a role of the PPAR-γ gene in altered glucose levels and psychosis profile in schizophrenia patients exposed to antipsychotics. Although the Pro12Ala at exon B has been concerned an essential variant in the development of obesity, the lack of association of the variant with metabolic traits in this study should not be treated as impossibility or a proof of error because other factors, e.g., genes regulated by PPAR-γ, may have complicated the development of metabolic abnormalities. Whether the PPAR-γ gene modifies the risk of metabolic abnormalities or psychosis, or causes metabolic abnormalities that lead to psychosis, remains to be examined.

      • KCI등재
      • KCI등재후보

        Differentiation and Categorization of Strategies: From Cases in Asia

        Yun-Chen Lai 연세대학교 미래사회통합연구센터 2019 Journal of Conflict and Integration Vol.3 No.1

        The word ‘strategy’ has been widely used, but poorly defined, in the IR area. Establishing a clear definition of the term is a precondition for effective policy-making and academic research. Hence, this article aims to build a systematic framework for analyzing strategy. Based on different perception of orders, goals, and policy instruments, this paper categorizes IR strategies into five types, including revisionist, engagement, status quo, accommodative and bandwagon, providing a systematic perspective for future studies in analyzing strategy. Examples of strategies taken by actors for dealing with Asian orders are given to elucidate the characteristics of each strategy type. The comparison on various strategies of conflict and cooperation outlines the current Asian order.

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