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      • SCISCIESCOPUS

        High-Contrast Infrared Absorption Spectroscopy via Mass-Produced Coaxial Zero-Mode Resonators with Sub-10 nm Gaps

        Yoo, Daehan,Mohr, Daniel A.,Vidal-Codina, Ferran,John-Herpin, Aurelian,Jo, Minsik,Kim, Sunghwan,Matson, Joseph,Caldwell, Joshua D.,Jeon, Heonsu,Nguyen, Ngoc-Cuong,Martin-Moreno, Luis,Peraire, Jaime,Al American Chemical Society 2018 NANO LETTERS Vol.18 No.3

        <P>We present a wafer-scale array of resonant coaxial nanoapertures as a practical platform for surface-enhanced infrared absorption spectroscopy (SEIRA). Coaxial nanoapertures with sub-10 nm gaps are fabricated via photolithography, atomic layer deposition of a sacrificial Al<SUB>2</SUB>O<SUB>3</SUB> layer to define the nanogaps, and planarization via glancing-angle ion milling. At the zeroth-order Fabry-Pérot resonance condition, our coaxial apertures act as a “zero-mode resonator (ZMR)”, efficiently funneling as much as 34% of incident infrared (IR) light along 10 nm annular gaps. After removing Al<SUB>2</SUB>O<SUB>3</SUB> in the gaps and inserting silk protein, we can couple the intense optical fields of the annular nanogap into the vibrational modes of protein molecules. From 7 nm gap ZMR devices coated with a 5 nm thick silk protein film, we observe high-contrast IR absorbance signals drastically suppressing 58% of the transmitted light and infer a strong IR absorption enhancement factor of 10<SUP>4</SUP>∼10<SUP>5</SUP>. These single nanometer gap ZMR devices can be mass-produced via batch processing and offer promising routes for broad applications of SEIRA.</P> [FIG OMISSION]</BR>

      • [Invited Paper] Using Approximate Multi-crane Frequencies for Input Shaper Design

        Joshua Vaughan,Jieun Yoo,William Singhose 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

        Cranes are the primary heavy lifter used in a wide array of industries. For the transport of large payloads, multiple cranes are often employed in a cooperative manner. One factor limiting the efficiency of all cranes is payload oscillation. For multi-crane lifts, the payload oscillation is a function of an array of crane and payload parameters, many of which are difficult to measure in real-time. This paper investigates the use of the estimates of the multi-crane natural frequencies in input shaper design. Two methods to design input shapers that rely only on the suspension cable lengths involved in the lift are presented. The accuracy of these estimations and the resulting effectiveness of input-shaping control are studied via simulation and experimental testing with a two-crane system.

      • KCI등재

        Concurrent Validity and Test-retest Reliability of the Core Stability Test Using Ultrasound Imaging and Electromyography Measurements

        Seungju Yoo,Nam-Gi Lee,Chanhee Park,Joshua (Sung) Hyun You 한국전문물리치료학회 2021 한국전문물리치료학회지 Vol.28 No.3

        Background: While the formal test has been used to provide a quantitative measurement of core stability, studies have reported inconsistent results regarding its test-retest and intra-observer reliabilities. Furthermore, the validity of the formal test has never been established. Objects: This study aimed to establish the concurrent validity and test-retest reliability of the formal test. Methods: Twenty-two young adults with and without core instability (23.1 ± 2.0 years) were recruited. Concurrent validity was determined by comparing the muscle thickness changes of the external oblique, internal oblique, and transverse abdominal muscle to changes in core stability pressure during the formal test using ultrasound (US) imaging and pressure biofeed-back, respectively. For the test-retest reliability, muscle thickness and pressure changes were repeatedly measured approximately 24 hours apart. Electromyography (EMG) was used to monitor trunk muscle activity during the formal test. Results: The Pearson’s correlation analysis showed an excellent correlation between trans-verse abdominal thickness and pressure biofeedback unit (PBU) pressure as well as internal oblique thickness and PBU pressure, ranging from r = 0.856–0.980, p < 0.05. The test-retest reliability was good, intraclass correlation coefficient (ICC1,2) = 0.876 for the core stability pressure measure and ICC1,2 = 0.939 to 0.989 for the abdominal muscle thickness measure. Conclusion: Our results provide clinical evidence that the formal test is valid and reliable, when concurrently incorporated into EMG and US measurements.

      • KCI등재

        Dual band Antenna Switch Module의 LTCC 공정변수에 따른 안정성 및 특성 개선에 관한 연구

        이중근,유찬세,유명재,이우성,Lee Joong-Keun,Yoo Joshua,Yoo Myung-Jae,Lee Woo-Sung 한국마이크로전자및패키징학회 2005 마이크로전자 및 패키징학회지 Vol.12 No.2

        본 논문은 LTCC 공정에 기반을 둔 GSM/DCS dual band 의 소형화된 antenna switch module을 공정변수 따른 특성의 왜곡을 안정화시키는 연구를 수행하였다. 특히 tape thickness의 변화에 따라 패턴간의 기생 커플링이 주된 변수로 작용한다. 두께 50um인 tape으로 제작된 시편의 사이즈는 $4.5{\times}3.2{\times}0.8 mm^3$이고 insertion loss는 Rx mode와 Tx mode 각각 ldB. 1.2dB 이하이다. 공정상에서 tape thickness의 변화에 따라 개발된 모듈의 특성 안정성을 검증하기 위해 각 블록-다이플렉서,필터, 바이어스 회로-을 probing method을 이용, 측정하였고, 각 블록간의 상호관계는 VSWR을 계산하여 비교하였다. 또한 회로적 관점에서 특성 개선을 위해 바이어스 회로부분의 집중소자형과 분포소자형을 구현하여 서로 비교 분석하였다. 이를 통해 각 블록의 측정과 계산된 VSWR의 데이터는 공정변수에 의해 변화된 전체 module의 특성과 안정성 거동을 파악하는데 좋은 정보를 준다. Tape thickness변화에도 불구하고 다이플렉스의 matching값은 연결되는 바이어스 회로와 LPF의 matching값과 상대 matching이 되면서, 낮은 VSWR을 유지하여 전체 insertion loss가 안정화되는 것을 확인하였다. 더불어 분포소자형 바이어스 회로보다는 집중소자형이 다른 회로블럭과의 관계에서 더 좋은 매칭을 이루어 loss개선에 일조하였다. Tape thickness가 6 um이상의 변화를 가져와도 집중소자형 바이어스 회로는 낮은 손실을 유지하여 더 넓은 안정 범위를 가져오기 때문에 양산에 적합한 구조가 될 수 있다 그리고, probing method에 의한 안정성 특성 추출은 세라믹에 임베디드된 수동회로들의 개발에 충분히 적용될 수 있다. A compact antenna switch module for GSM/DCS dual band applications based on multilayer low temperature co-fired ceramic (LTCC) substrate is presented. Its size is $4.5{\times}3.2{\times}0.8 mm^3$ and insertion loss is lower than 1.0 dB at Rx mode and 1.2 dB at Tx mode. To verify the stability of the developed module to the process window, each block that is diplexer, LPF's and bias circuit is measured by probing method in the variation with the thickness of ceramic layer and the correlation between each block is quantified by calculating the VSWR In the mean while, two types of bias circuits -lumped and distributed - are compared. The measurement of each block and the calculation of VSWR give good information on the behavior of full module. The reaction of diplexer to the thickness is similar to those of LPF's and bias circuit, which means good relative matching and low value of VSWR, so total insertion loss is maintained in quite wide range of the thickness of ceramic layer at both band. And lumped type bias circuit has smaller insertion itself and better correspondence with other circuit than distributed stripline structure. Evaluated ceramic module adopting lumped type bias circuit has low insertion loss and wider stability region of thickness over than 6um and this can be suitable for the mass production. Stability characterization by probing method can be applied widely to the development of ceramic modules with embedded passives in them.

      • KCI등재

        다층 구조를 적용한 Dual band 방향성 결합기 개발에 관한 연구

        유명재,유찬세,박성대,이우성,강남기,Yoo Myong Jae,Yoo Joshua,Park Seong Dae,Lee Woo S.,Kang Nam K. 한국마이크로전자및패키징학회 2004 마이크로전자 및 패키징학회지 Vol.11 No.2

        전력 결합기 및 전력 배분기는 마이크로파 수동 소자의 일종으로 전력을 결합하거나 나눌 때 쓰이는 것이다. 최근의 정보통신 시스템의 추세를 보아 수동 소자의 집적화 및 소형화가 요구된다. 본 연구에서는 이러한 추세를 감안하여 2012 크기의 다층 구조를 적용한 양대역 방향성 결합기를 저온 동시소성 기술을 활용하여 제작하였다. DCS(Digital communication system)와 EGSM(European global system for mobile) 대역에서 각기 원하는 커플링을 얻기 위해서 수직 결합 패턴들을 다층 구조에 적용하였다. 제작된 방향성 결합기의 결합성, 삽입 손실, 격리성 및 방향성 등의 특성들을 측정하였고 시뮬레이션 결과들과 비교 고찰하였다. A coupler or divider is a microwave passive component used for power coupling or dividing. Regarding the trend of current telecommunication systems monolithic integration of passive components is highly desirable. In this study by the LTCC(Low temperature co-fired ceramics) technology a 2012 size type dual band coupler with multi-layer structure was fabricated. To achieve the desired coupling values for both DCS and EGSM bands, broad side coupled patterns were used with multi-layer structure. Its characteristics such as coupling, insertion loss, isolation and directivity values were measured and compared with simulation results.

      • Launching the C-HPP neXt-CP50 Pilot Project for Functional Characterization of Identified Proteins with No Known Function

        Paik, Young-Ki,Lane, Lydie,Kawamura, Takeshi,Chen, Yu-Ju,Cho, Je-Yoel,LaBaer, Joshua,Yoo, Jong Shin,Domont, Gilberto,Corrales, Fernando,Omenn, Gilbert S.,Archakov, Alexander,Encarnació,n-Guevara American Chemical Society 2018 JOURNAL OF PROTEOME RESEARCH Vol.17 No.12

        <P>An important goal of the Human Proteome Organization (HUPO) Chromosome-centric Human Proteome Project (C-HPP) is to correctly define the number of canonical proteins encoded by their cognate open reading frames on each chromosome in the human genome. When identified with high confidence of protein evidence (PE), such proteins are termed PE1 proteins in the online database resource, neXtProt. However, proteins that have not been identified unequivocally at the protein level but that have other evidence suggestive of their existence (PE2-4) are termed missing proteins (MPs). The number of MPs has been reduced from 5511 in 2012 to 2186 in 2018 (neXtProt 2018-01-17 release). Although the annotation of the human proteome has made significant progress, the “parts list” alone does not inform function. Indeed, 1937 proteins representing ∼10% of the human proteome have no function either annotated from experimental characterization or predicted by homology to other proteins. Specifically, these 1937 “dark proteins” of the so-called dark proteome are composed of 1260 functionally uncharacterized but identified PE1 proteins, designated as uPE1, plus 677 MPs from categories PE2-PE4, which also have no known or predicted function and are termed uMPs. At the HUPO-2017 Annual Meeting, the C-HPP officially adopted the uPE1 pilot initiative, with 14 participating international teams later committing to demonstrate the feasibility of the functional <U>c</U>haracterization of large numbers of dark <U>p</U>roteins (CP), starting first with 50 uPE1 proteins, in a stepwise chromosome-centric organizational manner. The second aim of the feasibility phase to <U>c</U>haracterize protein (CP) functions of 50 uPE1 proteins, termed the neXt-CP50 initiative, is to utilize a variety of approaches and workflows according to individual team expertise, interest, and resources so as to enable the C-HPP to recommend experimentally proven workflows to the proteome community within 3 years. The results from this pilot will not only be the cornerstone of a larger characterization initiative but also enhance understanding of the human proteome and integrated cellular networks for the discovery of new mechanisms of pathology, mechanistically informative biomarkers, and rational drug targets.</P> [FIG OMISSION]</BR>

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