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        Equal Z standard-setting method to estimate the minimum number of panelists for a medical school’s objective structured clinical examination in Taiwan: a simulation study

        Ying-Ying Yang,Pin-Hsiang Huang,Ling-Yu Yang,Chia-Chang Huang,Chih-Wei Liu,Shiau-Shian Huang,Chen-Huan Chen,Fa-Yauh Lee,Shou-Yen Kao,Boaz Shulruf 한국보건의료인국가시험원 2022 보건의료교육평가 Vol.19 No.-

        Purpose Undertaking a standard-setting exercise is a common method for setting pass/fail cut scores for high-stakes examinations. The recently introduced equal Z standard-setting method (EZ method) has been found to be a valid and effective alternative for the commonly used Angoff and Hofstee methods and their variants. The current study aims to estimate the minimum number of panelists required for obtaining acceptable and reliable cut scores using the EZ method. Methods The primary data were extracted from 31 panelists who used the EZ method for setting cut scores for a 12-station of medical school’s final objective structured clinical examination (OSCE) in Taiwan. For this study, a new data set composed of 1,000 random samples of different panel sizes, ranging from 5 to 25 panelists, was established and analyzed. Analysis of variance was performed to measure the differences in the cut scores set by the sampled groups, across all sizes within each station. Results On average, a panel of 10 experts or more yielded cut scores with confidence more than or equal to 90% and 15 experts yielded cut scores with confidence more than or equal to 95%. No significant differences in cut scores associated with panel size were identified for panels of 5 or more experts. Conclusion The EZ method was found to be valid and feasible. Less than an hour was required for 12 panelists to assess 12 OSCE stations. Calculating the cut scores required only basic statistical skills.

      • Bicontinuous Fluid Structure with Low Cohesive Energy: Molecular Basis for Exceptionally Low Interfacial Tension of Complex Coacervate Fluids

        Huang, Kuo-Ying,Yoo, Hee Young,Jho, YongSeok,Han, Songi,Hwang, Dong Soo American Chemical Society 2016 ACS NANO Vol.10 No.5

        <P>An exceptionally low interfacial tension of a dense fluid of concentrated polyelectrolyte complexes, phase separated from a biphasic fluid known as complex coacervates, represents a unique and highly sought-after materials property that inspires novel applications from superior coating to wet adhesion. Despite extensive studies and broad interest, the molecular and structural bases for the unique properties of complex coacervates are unclear. Here, a microphase-separated complex coacervate fluid generated by mixing a recombinant mussel foot protein-1 (mfp-1) as the polycation and hyaluronic acid (HA) as the polyanion at stoichiometric ratios was macroscopically phase-separated into a dense complex coacervate and a dilute supernatant phase to enable separate characterization of the two fluid phases. Surprisingly, despite up to 4 orders of magnitude differing density of the polyelectrolytes, the diffusivity of water in these two phases was found to be indistinguishable. The presence of unbound, bulk-like, water in the dense fluid can be reconciled with a water population that is only weakly perturbed by the polyelectrolyte interface and network. This hypothesis was experimentally validated by cryo-TEM of the macroscopically phase-separated dense complex coacervate phase that was found to be a bicontinuous and biphasic nanostructured network, in which one of the phases was confirmed by staining techniques to be water and the other polyelectrolyte complexes. We conclude that a weak cohesive energy between water water and water polyelectrolytes manifests itself in a bicontinuous network, and is responsible for the exceptionally low interfacial energy of this complex fluid phase with respect to virtually any surface within an aqueous medium.</P>

      • An Application of Fiber-Connected Distributed Antennas to Heterogeneous Networks : Energy Efficiency Perspective

        Ying Sun,Yuxian Huang,Liming Chen 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1

        Fiber-connected distributed antenna systems (DAS) have been recognized as an effective means to accommodate the coverage and capacity demands of future heterogeneous networks (HetNet). Among various opportunities realized by the architecture, our focus in this paper is on the spectral efficiency (SE) advantages achieved by cooperative transmission and the associated power consumption that may affect the energy efficiency (EE) of the system. A detailed power model is developed to benchmark the various sources of energy consumption in fiber-connected DAS. Then a simple but efficient pre-coding scheme is proposed to reduce the computation complexity associated with cooperative transmission, thus lowering the power consumed by baseband processing while at the same time maintaining a high throughput performance. Through detailed and extensive simulations, this paper demonstrates the SE and EE advantages of the application of fiber-connected DAS in HetNet.

      • KCI등재

        Identification and Molecular Evolutionary Analysis of TLR5 Gene from the Tibetan macaque (Macaca thibetana)

        Ying Huang,Yong-Fang Yao,Yan Li,Qing-Yong Ni,Liang Zhou,Shuan-Ling Zhang,Wei Liu,Huai-Liang Xu 한국유전학회 2012 Genes & Genomics Vol.34 No.4

        In order to identify the Toll-like receptor 5 (TLR5) as a putative candidate disease-resistance gene in Tibetan macaque (Macaca thibetana), two pairs of primers were designed based on the TLR5 gene sequence of rhesus macaque (Macaca mulatta,NM_001130429). The primers were used to amplify the TLR5 gene from Tibetan macaque, by the polymerase chain reaction (PCR). The compiled sequences were analyzed by bioinformatics. The DNA sequencing and additional combined results showed that the Tibetan macaque TLR5 gene is about 2825 bp and contains an open reading frame of 2577 bp encoding for 858 amino acids. Homology analysis of TLR5 in both species showed that the amino acid and nucleotide identity is about 99.7% and 99.8% and their transmembrane and intracellular domains appeared more conservative than the extracellular domains of proteins. However, re-examining the entire Tibetan macaque TLR5 coding sequence we found that a purifying selection was also acting on the TLR5 gene region encoding for its intracellular domain of the protein. Even though the selection tests indicated that the TLR5 gene experienced a strong purifying selection in the process of evolution,most likely because its potential role in the primate adaptive immune defense, the Tibetan macaque still has the highest re-lationship with the rhesus macaque.

      • KCI등재

        Intravenous patient-controlled analgesia hydromorphone combined with pregabalin for the treatment of postherpetic neuralgia: a multicenter, randomized controlled study

        ( Ying Huang ),( Chenjie Xu ),( Tao Zeng ),( Zhongming Li ),( Yanzhi Xia ),( Gaojian Tao ),( Tong Zhu ),( Lijuan Lu ),( Jing Li ),( Taiyuan Huang ),( Hongbo Huai ),( Benxiang Ning ),( Chao Ma ),( Xinx 대한통증학회 2021 The Korean Journal of Pain Vol.34 No.2

        Background: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants, and lidocaine patches in reducing PHN, many patients still face intractable pain disorders. In this randomized controlled study, we evaluated whether hydromorphone through intravenous patient-controlled analgesia (IV PCA) was effective in relieving PHN. Methods: Patients with PHN were randomly divided into two groups, one group received oral pregabalin with IV normal saline, another group received oral pregabalin with additional IV PCA hydromorphone for two weeks. Efficacy was evaluated at 1, 4, and 12 weeks after the end of the treatments. Results: Two hundred and one patients were followed up for 12 weeks. After treatment, numerical rating scale (NRS) score of patients in the hydromorphone group was significantly lower than that of the control group, and the difference of NRS scores between the two groups was statistically significant at 4 and 12 weeks after treatment. The frequency of breakthrough pain in the hydromorphone group was significantly lower than that in the control group 1 and 4 weeks after treatment. After treatment, the quality of sleep in the hydromorphone group was significantly improved compared with the control group. The most common adverse reactions in the hydromorphone group were dizziness and nausea, with no significant respiratory depression. Conclusions: IV PCA hydromorphone combined with oral pregabalin provides superior pain relief in patients with PHN, which is worthy of clinical application and promotion.

      • KCI등재

        Motion Planning of Robot Manipulator Based on Improved NSGA-II

        Ying Huang,Minrui Fei 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.4

        In this paper, the trajectory of a robot manipulator is planned using the non-dominated sorting genetic algorithm II (NSGA-II). Moreover, consumed time, Cartesian trajectory length, and smooth movement are used as the multi-objective to be optimized [1, 2]. The Pareto optimal solution set is obtained through NSGA-II, and simulation is used to obtain and verify the results. In an actual engineering case, the optimal solution of the Pareto solution set can be selected as the optimal path of a robot manipulator. Results show that the relationship between consumed time and joint jerk is a priority solution to practical engineering selection. Moreover, the spatial distribution of the optimal solution set is improved by enhancing the proposed crowding distance mechanism in the conventional NSGA-II algorithm.

      • KCI등재

        Restorative Justice in Taiwan : An Overview

        Huang, Lan Ying 梨花女子大學校 法學硏究所 2010 法學論集 Vol.15 No.1

        대만의 법무부가 이제 막 처음으로 “회복적 사법 프로그램”의 도입에 착수하고 있음에도 불구하고, 2000년 이후 이 계획은 공적 담론과 학계 연구의 중심에 있어 왔다. 이러한 회복적 사법 촉구의 배경에는 다음과 같은 것들이 있다. 전통적으로, 식민지배 이후 대만 사회는 공식적이고 투명한 사법기관들을 비공식적인 기관들이 대체하는 ‘안으로는 유교적, 밖으로는 법률 존중주의적’ 사회로 묘사되어 왔다. 대만 사람들에게는 대체적 분쟁해결수단을 널리 활용해 온 오랜 역사가 있으며, 얼마 전부터 정부는 사법적 인권을 고취시키자는 압력도 계속 받고 있다. ‘당사자주의’의 도입은 피해자의 권리 보장에 효과적이지 않은 것처럼 여겨진다. 사형제도 폐지라는 논란이 많은 이슈도 피해자 운동의 또 다른 흐름이다. 복수의 목적을 달성하기 위한 형사사법제도의 개혁은 정부의 우선적인 과제 중 하나다. 이 논문에서는 회복적 사법의 세 가지 실용적인 유형에 대하여 언급하고자 한다: 소년사법제도, 참여식 사법, 그리고 형사사건에 있어서의 중재이다. 끝으로 필자는 2000년 법무부가 추진하였던 회복적 사법 프로그램의 배경에 대하여 살펴보기 위하여, 현재의 법적 구조에 대하여 비판적으로 검토해 보고자 한다. Although the ministry of justice in Taiwan is just beginning to initiate the first “restorative justice programme”, the idea has been the focus of both official discourse and academic investigation since 2000. There are a few forces behind this newly emerged restorative justice urge. Traditionally, post colonization Taiwan society is described as an ‘inwardly Confucian, outwardly legalistic’ (內儒外法) society, in which informal institutions preempted the transplanted formal legal institutions. The Taiwan people have a long history of using alternative dispute resolution mechanism. More recently, the government is under increasing pressure of promoting judicial human right. The introduction of adversary system can not be deemed beneficial of promoting victim’s right. The controversial issue of abolishing death penalty also rises another wave of victim movement. The reform of criminal justice system to serve multiple purposes has become one of the prioritized government agenda. In this article, I describe three practical forms of restorative justice: juvenile justice system (少年司法制度), participatory justice (參與式司法), and mediation service for criminal cases (刑事案件調解). In the end, I critically review the current legal structure to address the background of the 2010 restorative justice programme under Ministry of Justice (法務部修復式司法試行方案).

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