Correction to: Simulation of Counter-Rotating Vortex Pairs on a Triangular-Flapped Wing with Flap-Tip Free Vortex Modeling

Woo-Ram Kang,Se Hwan Park,이덕주 한국항공우주학회 2018 International Journal of Aeronautical and Space Sc Vol.19 No.4

The article “Simulation of Counter-Rotating Vortex Pairs on a Triangular-Flapped Wing with Flap-Tip Free Vortex Modeling”, written by Woo-Ram Kang, Se Hwan Park and Duck-Joo Lee, was originally published electronically on the publisher’s internet portal (currently SpringerLink) on 08 September 2018 with open access. With the author(s)’ decision to step back from Open Choice, the copyright of the article changed on 24 October 2018 to © The Korean Society for Aeronautical & Space Sciences and Springer Nature Singapore Pte Ltd. 2018 and the article is forthwith distributed under the terms of copyright. The original article has been corrected.

내용기반 이미지 검색을 위한 문자-에지 맵의 특징을 이용한 자연이미지에서의 텍스트 영역 추출

박종천,황동국,이우람,권교현,전병민 충북대학교 컴퓨터정보통신 연구소 2006 컴퓨터정보통신연구 Vol.14 No.2

자연이미지에 포함된 텍스트는 많은 중요한 정보를 포함하고 있다. 그러므로 자연이미지에서 텍스트를 추출할 수 있다면 다양한 분야에서 활용될 수 있다. 본 논문에서는 문자-에지 맵 패턴 히스토그램을 분석함으로서 텍스트 영역을 추출하는 방법을 제안한다. 첫 번째 단계로, Canny 에지 검출기로 에지를 추출하여 16가지 에지 맵을 생성하고, 두 번째 단계로 16가지 에지 맵을 조합하여 문자 특징을 갖는 8가지 문자-에지 맵을 생성한다. 세 번째 단계로 8가지 문자-에지 맵과 16가지 에지 맵을 이용하여 텍스트 후보 영역을 추출 하고, 마지막으로 텍스트 후보 영역에 대한 검증은 문자-에지 맵의 패턴 히스토그램 및 텍스트 영역의 구조적 특징을 이용하여 수행하였다. 실험결과 제안한 방법은 복잡한 배경, 다양한 글꼴, 다양한 텍스트 컬러로 구성된 자연이미지에서 텍스트 영역을 효과적으로 추출하였다. The text to be included in the natural images has many important information. Therefore, if we can extract the text in natural images, it can be applied to many important applications. In this paper, we propose a text region extraction method using pattern histogram of character-edge maps. In the first step, we extract edges with the Canny edge detector and create 16 kinds of edge maps from the extracted edges. In the second step, we make 8 kinds of character-edge maps that has a character features with combination of edge maps. In the third step, we extract a text regions using 8 kinds of character-edge maps and 16 kinds of edge maps. Finally, verification about candidate of the text regions uses pattern histogram of character-edge maps and structural features of text regions. The proposed method is experimented with various kinds of natural images. Experimental results show that the proposed method extracts a text regions composed of complex background, various letters, various text colors effectively.

전사억제인자 Small Hetrodimer Partner-Interacting Leucine Zipper(SMILE)의 당대사와 지질대사 조절

박우람,최병윤,사다시밤 난티니,김돈규 전남대학교 농업과학기술연구소 2022 농업생명과학연구동향 Vol.60 No.-

Small heterodimer partner-interacting leucine zipper (SMILE) is a member of the cAMP response element-binding protein / activator transcription factor (CREB/ATF) family of basic leucine zipper (bZIP) transcription factors. Structurally, it exists in small and long isoforms resulting from alternative usage of the initiation codon. Though structurally similar to bZIP proteins, SMILE cannot bind to DNA but can homodimerize like them. SMILE acts as a corepressor for nuclear receptors related transcriptional activity and other transc- ription factors. SMILE plays a crucial role in metabolic signaling pathways by inhibiting DNA binding, competing with coactivators, and directly repressing transcription. This review focuses on the role of SMILE in hepatic glucose and lipid metabolism. Regulation of SMILE improves pathological conditions such as hepatitis, diabetes and fatty liver disease. Therefore, understanding the role of SMILE in metabolism and signaling pathways paves the way to consider SMILE as a potential target in treating liver metabolic diseases.

Comparative Analysis of Physicochemicals and Antioxidative Properties of New Giant Embryo Mutant, YR23517Acp79, in Rice (Oryza sativa L.)

Woo Duck Seo,김준영,Dong-Soo Park,Sang-Ik Han,장기창,Kyung-Jin Choi,Sang-Yeol Kim,오성환,나지은,Gihwan Yi,Soo-Kwon Park,Woon-Ha Hwang,송유천,Bo-Ram Park,강항원 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.5

Nutritional and physicochemical properties of new giant embryo mutant rice (YR23517Acp79, YR) were analyzed. YR exhibited increased total protein (9.3±0.3%), lipid (3.7±1.1%), amino acid (663.28±1.9 mg/g), and mineral contents (Ca=284.0±6.2, Mg=1417.5±13.6 mg/kg). In YR brown rice four major physicochemicals, including gamma-aminobutyric acid (brown rice= 0.46±0.014mg/g), γ-oryzanol (0.43±0.021 mg/g), vitamin B1 (6.42±0.3 mg/kg), and tocopherols (alpha=2.68±0.1, beta=0.11±0.01, gamma=0.05±0.001 mg/100 g) increased in comparison to reported giant embryo (Keunnunbyeo, KB) and normal embryo rice (Ilmibyeo, IB). YR showed higher scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (0.2 g/mL=57.1±2.25) and 2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (0.2 g/mL=50.2±1.45) radicals but also inhibited lipopolysaccharide-induced nitric oxide production without cytotoxicity. These results indicate YR is a high quality functional rice due to its high nutrition content and antioxidant effects of physicochemicals.

Carboxy-Terminal Region of a Thermostable CITase from Thermoanaerobacter thermocopriae Has the Ability to Produce Long Isomaltooligosaccharides

( Woo Soo Jeong ),( Yu-ri Kim ),( Seong-jin Hong ),( Su-jeong Choi ),( Ji-ho Choi ),( Shin-young Park ),( Eui-jeon Woo ),( Young Min Kim ),( Bo-ram Park ) 한국미생물 · 생명공학회 2019 Journal of microbiology and biotechnology Vol.29 No.12

Isomaltooligosaccharides (IMOs) have good prebiotic effects, and long IMOs (LIMOs) with a degree of polymerization (DP) of 7 or above show improved effects. However, they are not yet commercially available, and require costly enzymes and processes for production. The Nterminal region of the thermostable Thermoanaerobacter thermocopriae cycloisomaltooligosaccharide glucanotransferase (TtCITase) shows cyclic isomaltooligosaccharide (CI)-producing activity owing to a catalytic domain of glycoside hydrolase (GH) family 66 and carbohydrate-binding module (CBM) 35. In the present study, we elucidated the activity of the C-terminal region of TtCITase (TtCITase-C; Met740-Phe1,559), including a CBM35-like region and the GH family 15 domain. The domain was successfully cloned, expressed, and purified as a single protein with a molecular mass of 115 kDa. TtCITase-C exhibited optimal activity at 40°C and pH 5.5, and retained 100% activity at pH 5.5 after 18-h incubation. TtCITase-C synthesized α-1,6 glucosyl products with over seven degrees of polymerization (DP) by an α-1,6 glucosyl transfer reaction from maltopentaose, isomaltopentaose, or commercialized maltodextrins as substrates. These results indicate that TtCITase-C could be used for the production of α-1,6 glucosyl oligosaccharides with over DP7 (LIMOs) in a more cost-effective manner, without requiring cyclodextran.

한반도에 영향을 미친 태풍 경로별 재해평가모형의 활용도 분석

박종길 ( Jong-kil Park ),이보람 ( Bo-ram Lee ),정우식 ( Woo-sik Jung ) 한국환경과학회 2016 한국환경과학회지 Vol.25 No.11

As a result of dividing typhoon that affected Korean Peninsular between 1999 and 2012 into 7 types of path and entering forecast field and analysis field of RDAPS, until 36 hours from the time of forecast, it is reliable to use the forecast field of RDAPS to predict typhoon and for each typhoon path, the difference between the forecast and the analysis shows normal distribution, which is usable for weather forecast until the 36^th hour. In the 48^th hour from the time of forecast, the difference of result depending on each typhoon path increased, which was analyzed to be due to errors in the forecast. It was expected that relatively reasonable results should be shown if the 36^th hour forecast is used to predict the strength and distribution of strong wind. As a result of using Korean RAM and observing the difference of the maximum damage, reliability was secured up to 36 hours and after 48hours, it was expected that the fluctuation of results may become more severe.

Data Firewall: A TPM-based Security Framework for Protecting Data in Thick Client Mobile Environment

Park, Woo-Ram,Park, Chan-Ik Korean Institute of Information Scientists and Eng 2011 Journal of Computing Science and Engineering Vol.5 No.4

Recently, Virtual Desktop Infrastructure (VDI) has been widely adopted to ensure secure protection of enterprise data and provide users with a centrally managed execution environment. However, user experiences may be restricted due to the limited functionalities of thin clients in VDI. If thick client devices like laptops are used, then data leakage may be possible due to malicious software installed in thick client mobile devices. In this paper, we present Data Firewall, a security framework to manage and protect security-sensitive data in thick client mobile devices. Data Firewall consists of three components: Virtual Machine (VM) image management, client VM integrity attestation, and key management for Protected Storage. There are two types of execution VMs managed by Data Firewall: Normal VM and Secure VM. In Normal VM, a user can execute any applications installed in the laptop in the same manner as before. A user can access security-sensitive data only in the Secure VM, for which the integrity should be checked prior to access being granted. All the security-sensitive data are stored in the space called Protected Storage for which the access keys are managed by Data Firewall. Key management and exchange between client and server are handled via Trusted Platform Module (TPM) in the framework. We have analyzed the security characteristics and built a prototype to show the performance overhead of the proposed framework.

Poly(Ethylene Glycol)-branched Polyethylenimine-poly(L-phenylalanine) Block Copolymer Synthesized by Multi-initiation Method for Formation of More Stable Polyelectrolyte Complex with Biotherapeutic Drugs

( Woo Ram Park ),( Kun Na ) 한국약제학회 2011 Journal of Pharmaceutical Investigation Vol.41 No.2

An amphiphilic cationic branched methoxy poly (ethylene glycol)-branched polyethylenimine-poly(L-phenylalanine) (mPEG-bPEI-pPhe) block copolymer was successfully synthesized by ring-opening polymerization (ROP) of N-carboxyanhydride of L-phenylalanine (Phe-NCA) with mPEG-bPEI for the preparation of more stable polyelectrolyte complex (PEC) included a hydrophobic interaction. mPEG-bPEI was firstly prepared by the coupling of mPEG and bPEI using hexamethylene diisocyanate (HMDI). The structural properties of mPEG-bPEI-pPhe copolymers were confirmed by 1H NMR. The copolymers exhibited a self-assemble behavior in water above critical aggregate concentration (CAC) in the range of 0.01-0.14 g/L. The CAC of copolymers obviously depended on the hydrophobic block content in the copolymers (the value decreased with the increase of the pPhe block content). The cationic copolymers have the ability to form multi-interaction complex (MIC) with bovine serum albumin (BSA) and plasmid DNA through multi-interaction (electrostatic and hydrophobic interaction). The physicochemical characterization of the complex was carried out by the measurement of zeta potential and particle size. Their zeta-potentials were positive (approximately +10 mV) and their sizes decreased with increasing pPhe contents in the copolymers (PPF/BSA wt% ratio=2). The complex showed good stability at high ionic strength. Therefore, mPEG-bPEI-pPhe block copolymer was considered as a potential material to enhance the stability of complex including biotherapuetic drugs.

Effect of Bee Venom on Transforming Growth Factor-β1-Treated Hepatocytes

Park, Jung-Hyun,Kim, Kyung-Hyun,Kim, Soo-Jung,Lee, Woo-Ram,Lee, Kwang-Gill,Park, Ji-Hyun,Park, Kwan-Kyu SAGE Publications 2010 International journal of toxicology Vol.29 No.1

<P> Bee venom (BV) has been used as treatment against a wide variety of ailments, including inflammatory diseases. Various studies have demonstrated anti-inflammatory and anticancer effects of BV. Transforming growth factor (TGF)-β1 induces hepatocyte apoptosis via the mitochondrial permeability transition. However, there is no evidence or information regarding the antiapoptotic effect of BV on hepatocytes. The authors investigated the antiapoptotic effect of BV on TGF-β1-treated hepatocytes. The results showed significant protection from DNA damage by BV treatment compared to corresponding TGF-β1-treated hepatocytes without BV. BV suppressed TGF-β1-induced activation of the bcl-2 family and caspase family of proteins, which resulted in inhibition of poly ADP-ribose polymerase (PARP) cleavage. Furthermore, BV is not cytotoxic in the low concentrations used in this study. Low concentrations of BV potently suppress the apoptotic response in TGF-β1-treated hepatocytes; therefore, BV may have therapeutic potential for the treatment of liver diseases. </P>

Effects of Center of Pressure on Muscle Activations and Joint Range of Motion of Lower Extremities during Squat

( Woo Ram Yoon ),( Sang Heon Park ),( Chan Hyeok Jeong ),( Ji Ho Park ),( Suk-hoon Yoon ) 한국운동역학회 2018 한국운동역학회지 Vol.28 No.1

Objective: The aim of this study was to analyze muscle activation of the lower extremities as a function of changes of the center of pressure (CoP) of the foot during squats in order to provide quantitative information to trainers who would like to teach correct movements for developing muscles. Method: Ten men with over three years of weight training experience participated in this study (age: 26.1 ± 0.8 yrs, height: 171.2 ± 3.9 cm, body mass: 71.1 ± 5.7 kg, 60%RM: 84 ± 9 kg, career: 4.0 ± 0.7 yrs). The participants were instructed to perform a squat in each of 3 conditions, with different CoP's (the front, middle, and rear of the foot). Results: The position of the CoP showed significant differences according to instructions in both the eccentric and concentric contraction phases (p < .05). The range of movement of the hip and ankle joints showed significant differences corresponding to changes of the CoP position (p < .05). The rectus femoris and gluteus maximus muscle showed significant differences for different CoP positions only in the concentric contraction phase, while the gastrocnemius and anterior tibialis were significantly different in both the concentric and eccentric contraction phase (p < .05). Conclusion: When the target muscle of squat training is the gastrocnemius, the CoP should be located in the front of the foot for effective muscle training. When the target muscles of squat training are the gluteus maximus and quadriceps femoris, the CoP should be located on the rear of the foot.