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Van-Long Tran,Dai-Duong Tran,Van-Tuan Doan,Ki-Young Kim,Woojin Choi 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.1
In this paper, a novel hybrid configuration combining a phase-shift full-bridge (PSFB) and a half-bridge resonant LLC converter is proposed for the On-Board Charger of Electric Vehicles (EVs). In the proposed converter, the PSFB converter shares the lagging-leg switches with half-bridge resonant converter to achieve the wide ZVS range for the switches and to improve the efficiency. The output voltage is modulated by the effective-duty-cycle of the PSFB converter. The proposed converter employs an active reset circuit composed of an active switch and a diode for the transformer which makes it possible to achieve zero circulating current and the soft switching characteristic of the primary switches and rectifier diodes regardless of the load, thereby making the converter highly efficient and eliminating the reverse recovery problem of the diodes. In addition an optimal power sharing strategy is proposed to meet the specification of the charger and to optimize the efficiency of the converter. The operation principle the proposed converter and design considerations for high efficiency are presented. A 6.6 kW prototype converter is fabricated and tested to evaluate its performance at different conditions. The peak efficiency achieved with the proposed converter is 97.7%.
Tran, Van-Long,Tran, Dai-Duong,Doan, Van-Tuan,Kim, Ki-Young,Choi, Woojin The Korean Institute of Electrical Engineers 2018 Journal of Electrical Engineering & Technology Vol.13 No.1
In this paper, a novel hybrid configuration combining a phase-shift full-bridge (PSFB) and a half-bridge resonant LLC converter is proposed for the On-Board Charger of Electric Vehicles (EVs). In the proposed converter, the PSFB converter shares the lagging-leg switches with half-bridge resonant converter to achieve the wide ZVS range for the switches and to improve the efficiency. The output voltage is modulated by the effective-duty-cycle of the PSFB converter. The proposed converter employs an active reset circuit composed of an active switch and a diode for the transformer which makes it possible to achieve zero circulating current and the soft switching characteristic of the primary switches and rectifier diodes regardless of the load, thereby making the converter highly efficient and eliminating the reverse recovery problem of the diodes. In addition an optimal power sharing strategy is proposed to meet the specification of the charger and to optimize the efficiency of the converter. The operation principle the proposed converter and design considerations for high efficiency are presented. A 6.6 kW prototype converter is fabricated and tested to evaluate its performance at different conditions. The peak efficiency achieved with the proposed converter is 97.7%.
Intelligent Charger with Online Battery Diagnosis Function
Van-Tuan Doan,Van-Binh Vu,Hai-Nam Vu,Duc-Hung Tran,Woojin Choi 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
In the battery based applications, the performance of the system highly depends on the reliability of the battery. However, it is difficult to obtain the accurate information about the state-of-health (SOH) of battery during its operation. In this paper a 3kw battery charger with online battery diagnosis function which can estimate the SOH of the battery by using online impedance spectroscopy technique is introduced. For the charger, a phase shift full bridge converter with synchronous rectification has been adopted to implement constant current/constant voltage charge and diagnosis functions. The electrochemical impedance spectroscopy (EIS) is performed after the charge to obtain the information about the internal impedance of the battery module, hence the SOH can be estimated online by observing the impedance variation of the battery over time. All the design procedure of the proposed charger is detailed and the feasibility of the system is verified by the experimental results.
Tran, Tuan Hiep,Nguyen, Hanh Thuy,Le, Nam Van,Tran, Thi Thu Phuong,Lee, Jong Seong,Ku, Sae Kwang,Choi, Han-Gon,Yong, Chul Soon,Kim, Jong Oh Elsevier 2017 International journal of pharmaceutics Vol.528 No.1
<P><B>Abstract</B></P> <P>Heterogeneity of cancer cells and drug resistance require multiple therapeutic approaches for comprehensive treatment. In this study, temperature-sensitive liposomes containing anti-cancer agent tanespimycin (17-AAG) and photosensitizer IR 820 were developed for combination of phototherapy and chemotherapy. The temperature-sensitive liposomes composed of DPPC, cholesterol, DSPE-PEG, 17-AAG, and IR 820 (LP-AI) at weight ratio of 35/15/3/2/2 were formulated as a thin film using extrusion and evaluated for particle size, morphology and drug release profile. Furthermore, the anticancer effect of combined therapy was examined <I>in vitro</I> and <I>in vivo</I> in SCC-7 and MCF-7 cell lines. As a result, LP-AI was prepared at particle size of 166.7±1.3nm, PDI of 0.153±0.012, and ζ-potential of −32.6±0.8mV. After NIR irradiation (660 and 808nm laser), LP-AI could generate heat and ROS and enhance drug release from nanoparticles which were useful to kill the cancer cells. These were confirmed by <I>in vitro</I> cytotoxicity as well as <I>in vivo</I> effective ablation of tumors. In conclusion, fast drug release and enhanced treatment efficacy of LP-AI indicate the potential of integrating photo- and chemotherapy for synergistic anti-cancer effects.</P> <P><B>Graphical abstract</B></P> <P>Temperature-sensitive liposomes containing anti-cancer agent tanespimycin and photosensitizer IR 820 (LP-AI).</P> <P>[DISPLAY OMISSION]</P>
( Tuan Hiep Tran ),( Tuan Duc Nguyen ),( Han Van Nguyen ),( Hanh Thuy Nguyen ),( Jong Oh Kim ),( Chul Soon Yong ),( Chien Ngoc Nguyen ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
Polyro.t-lactic-co-glycolic acid) (PLGA) nanoparticles with negative surface charge were reversed to positive by cationic surfactant-DDAB before being coated with an anionic polymer, hyaluronic acid, to improve their site-specific intracellular delivery against CD44 receptor overexpressing cancer cells. Incorporating artesunate (ART)-a promising anticancer drug into PLGA/HA nanoparticles, is expected not only to overcome its poor aqueous solubility and stability but also enhance the activities. The obtained particles were characterized by dynamic light scattering, zeta potential measurements, and transmission electron microscopy (TEM). Cancer cell internalization of the NPs was evaluated by flow cytometry and cytotoxicity of the NPs was tested by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay. PLGA/HA nanoparticles showed greater extent of cellular uptake to SCC-7 and MCF-7 cells, indicating their affinity with CD44 receptor-mediated endocytosis. Almost 60 % of ART was released into the outer media after 48 h. In vitro fluorescence sorting demonstrated that PLGA/HA had highly efficient targeting and accumulation into CD44 receptor overexpression cells. The significant reduction in cell viability as well as greater induction of apoptosis suggested a potential in anticancer therapy of ART loaded PLGA/HA.
Unipolar Resistance Switching Characteristics in a Thick ZnO/Cu/ZnO Multilayer Structure
Tran Le,Hoang Cao Son Tran,Van Hieu Le,Tuan Tran,Cao Vinh Tran,Thanh Tan Vo,Mau Chien Dang,김상섭,이재찬,Bach Thang Phan 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.60 No.7
The resistance switching mechanism and the electrical conduction of thick Cu/ZnO/Cu/ZnO/Cu structures were investigated for various ZnO thicknesses (40, 80, 160, and 320 nm) when the thickness of the middle Cu layer was 2 nm. The ZnO films had a microstructure with columnar grains normal to the substrate. The switching voltages (VSET and VRESET) varied with the thickness of the ZnO layer. A symmetric electrode structure exhibited a unipolar resistance switching. The electrical transport of both high-resistance state (HRS) and low-resistance state (LRS) was Ohmic conduction, and the resistance switching mechanism was driven by the formation and the rupture of Cu conducting paths.
Tobacco Control Policies in Vietnam: Review on MPOWER Implementation Progress and Challenges
Hoang, Van Minh,Tran, Thu Ngan,Vu, Quynh Mai,Nguyen, Thi Tuyet My,Le, Hong Chung,Vu, Duy Kien,Tran, Tuan Anh,Nguyen, Bao Ngoc,Vu, Van Giap,Nguyen, Manh Cuong,Pham, Duc Manh,Kim, Bao Giang Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1
In Vietnam, the WHO Framework Convention on Tobacco Control (WHO FCTC) took effect in March 2005 while MPOWER has been implemented since 2008. This paper describes the progress and challenges of implementation of the MPOWER package in Vietnam. We can report that, in term of monitoring, Vietnam is very active in the Global Tobacco Surveillance System, completing two rounds of the Global Adult Tobacco Survey (GATS) and three rounds of the Global Youth Tobacco Survey (GYTS). To protect people from tobacco smoke, Vietnam has issued and enforced a law requiring comprehensive smoking bans at workplaces and public places since 2013. Tobacco advertising and promotion are also prohibited with the exception of points of sale displays of tobacco products. Violations come in the form of promotion girls, corporate social responsibility activities from tobacco manufacturers and packages displayed by retail vendors. Vietnam is one of the 77 countries that require pictorial health warnings to be printed on cigarette packages to warn about the danger of tobacco and the warnings have been implemented effectively. Cigarette tax is 70% of factory price which is equal to less than 45% of retail price and much lower than the recommendation of WHO. However, Vietnam is one of the very few countries that require manufacturers and importers to make "compulsory contributions" at 1-2% of the factory price of cigarettes sold in Vietnam for the establishment of a Tobacco Control Fund (TCF). The TCF is being operated well. In 2015, 67 units of 63 provinces/cities, 22 ministries and political-social organizations and 6 hospitals received funding from TCF to implement a wide range of tobacco control activities. Cessation services have been starting with a a toll-free quit-line but need to be further strengthened. In conclusion, Vietnam has constantly put efforts into the tobacco control field with high commitment from the government, scientists and activists. Though several remarkable achievements have been gained, many challenges remain. To overcome those challenges, implementation strategies that take into account the contextual factors and social determinants of tobacco use in Vietnam are needed.
Loi Van Le,Quang Van Vu,Thanh Van Le,Hieu Trung Le,Khue Kim Dang,Tuan Ngoc Vu,Anh Hoang Ngoc Nguyen,Thang Manh Tran 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1
Backgrounds/Aims: Hepatolithiasis and choledocholithiasis are frequent pathologies and unfortunately, with the current treatment strategies, the recurrence incidence is still high. This study aimed to assess the outcomes of laparoscopic choledochotomy using cholangioscopy via the percutaneous-choledochal tube for the treatment of hepatolithiasis and choledocholithiasis in Vietnamese patients. Methods: A cross-sectional study of patients with hepatolithiasis and/or choledocholithiasis who underwent laparoscopic choledochotomy using intraoperative cholangioscopy via percutaneous-choledochal tube at the Department of Hepatopancreatobiliary Surgery, 108 Military Central Hospital, from June 2017 to March 2020. Results: A total of 84 patients were analyzed. Most patients were females (56.0%) with a median age of 55.56 years. Among them, 41.8% of patients had previous abdominal operations, with 33.4% having choledochotomy. All patients underwent successful laparoscopic common bile duct exploration followed by T-tube drainage without needing to convert to open surgery. Most patients (64.3%) had both intrahepatic and extrahepatic stones. The rate of stones ≥ 10 mm in diameter was 64.3%. Biliary strictures were observed in 19.1% of patients during cholangioscopy. Complete removal of stones was achieved in 54.8% of patients. Intraoperative complications were encountered in two patients, but there was no need to change the strategy. The mean operating time was 121.85 ± 30.47 minutes. The early postoperative complication rate was 9.6%, and all patients were managed conservatively. The residual stones were removed through the T-tube tract by subsequent choledochoscopy in 34/38 patients, so the total success rate was 95.2%. Conclusions: Laparoscopic choledochotomy combined with cholangioscopy through the percutaneous-choledochal tube is a safe and effective strategy for hepatolithiasis and/or choledocholithiasis, even in patients with a previous choledochotomy.
Chu Van Tuan,Mai Anh Tuan,Nguyen Van Hieu,Tran Trung 한국물리학회 2012 Current Applied Physics Vol.12 No.4
In this work, we have successfully developed a facile and effective electrochemical route for directly growing polyaniline (PANI) nanowires (NWs) on platinum interdigitated microelectrode. The asprepared NWs were characterized by field-emission scanning electron microscopy, transmission electron microscopy and Fourier-transform infrared spectroscopy. They revealed that the PANI NWs were obtained with diameters ranging from 50 to 200 nm and length up to hundreds of micro meters,depending on growth time. The as-obtained PANI NWs on the electrode exhibited a porous nature and the conducting emeraldine type structure. The gas sensing properties of PNAI NWs were explored by monitoring NH3 in synthetic air in the concentration range of 25-500 ppm at room temperature. The results obtained demonstrated that PANI NWs have good potential as novel room temperature sensors for practical applications.