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Sutradhar Jugal,Sarkar Bapi Ray 대한약침학회 2021 Journal of pharmacopuncture Vol.24 No.4
The COVID-19, the most infectious pandemic disease arising due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has caused huge issues globally. In this review, we discuss the impact of COVID-19 on the immune system of the human body and the protective mechanisms of the host immune system opposing viral infections. Here, we summarize the effect of the pandemic of the novel coronavirus disease on the immune system such as sleep and Behavioral Immune System (BIS) together with consideration of researcher’s observation points of view. We draw particular attention to recent up-to-date reports concerning COVID-19 drugs as well as information about the landscape document for COVID-19 vaccines released by WHO (World Health Organization), and some adverse events of COVID-19 vaccination. Additionally, can take part in the preventive appraise in opposition within this pandemic severe COVID-19 infections disease may affect some outcome in physical exercise, physical movement, healthy diets, and good nutrition are significant for supporting the immune systems and summarize AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) Indian medicinal systems guidelines for immunity boosting procedures during COVID-19 pandemic.
Sutradhar, S.C.,Jang, H.,Banik, N.,Yoo, J.,Ryu, T.,Yang, H.,Yoon, S.,Kim, W. Pergamon Press ; Elsevier Science Ltd 2017 International journal of hydrogen energy Vol.42 No.17
<P>A series of poly(phenylenebenzophenone)s with sulfonic acid groups via long alkyl side chains, SPPBPs, were successfully prepared as proton exchange membranes for fuel cells. The new monomer, 1,4-dichloro-2,5 diphenylenemethoxybenzophenone (PMBP) was synthesized by the Friedel Crafts reaction of tetrachloroterephthalate with anisole and copolymerized with 1,4-dichloro-2,5-diphenylenebenzophenone (PBP) to prepare poly(phenylenebenzophenone)s copolymers containing dimethoxy groups (sPPMBP). After converting the methoxy group to the reactive hydroxyl group, the resulting side-chain-type sulfonated copolymers (SPPBP) were obtained by a sulfopropylation reaction. These SPPBP series membranes showed high proton conductivity in the range of 98.4-162.1 mS/cm 80 degrees C under 90% hydrated conditions. SPPBP-40 (IEC = 2.45 meq./g) showed comparable higher proton conductivity (162.1 mS/cm) than Nafion 211 (130.2 mS/cm) in the 90% hydrated state. The membranes were studied by H-1 NMR spectroscopy, thermo-gravimetric analysis, ionic exchange capacity, water uptake, and proton conductivity. Also surface morphologies were assessed by atomic force microscope (AFM). (C) 2016 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.</P>
Sabuj Chandra Sutradhar,Md Mahabubur Rahman,Faiz Ahmed,류태욱,윤수진,이승찬,김재웅,이용훈,Yongcheng Jin,김환기 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.76 No.-
Thermally and chemically stable sulfonated poly(phenylenebenzophenone)s (SPPBP) membranes havebeen synthesized from 1,4-dichloro-2,5-diphenylene methoxy benzophenone (PMBP) and 1,4-dichloro-2,5-dibenzoyl benzene (PBP) monomers by using Ni (0) catalyst for proton exchange membrane fuel cells(PEMFC). The synthesized SPPBP membranes exhibited ion exchange capacity from 1.18 to 2.30 meq/g.,water uptake from 34.2 to 78.3% and proton conductivity from 36.94 to 92.90 mS/cm. Additionally, the C–C coupling polymerization improved the thermal and chemical stability of the SPPBP membranes. Furthermore, the pendent benzophenone acid moiety provided the well hydrophilic/hydrophobic phaseseparation morphology with increased conductivity. Therefore, the SPPBP membranes can be a potentialcandidate for proton exchange membrane fuel cell (PEMFC).
Comparison between open and closed methods of herniorrhaphy in calves affected with umbilical hernia
Bibek Chandra Sutradhar,Mohammad Farhad Hossain,Bhajan Chandra Das,김근형,Mohammad Alamgir Hossain 대한수의학회 2009 JOURNAL OF VETERINARY SCIENCE Vol.10 No.4
Umbilical hernias in calves commonly present to veterinary clinics, which are normally secondary to failure of the normal closure of the umbilical ring, and which result in the protrusion of abdominal contents into the overlying subcutis. The aim of this study was to compare the suitability of commonly-used herniorrhaphies for the treatment of reducible umbilical hernia in calves. Thirty-four clinical cases presenting to the Veterinary Teaching Hospital, Chittagong Veterinary and Animal Sciences University, Chittagong, Bangladesh from July 2004 to July 2007 were subjected to comprehensive study including history, classification of hernias, size of the hernial rings, presence of adhesion with the hernial sacs, postoperative care and follow-up. They were reducible, nonpainful and had no evidence of infection present on palpation. The results revealed a gender influence, with the incidence of umbilical hernia being higher in female calves than in males. Out of the 34 clinical cases, 14 were treated by open method of herniorrhaphy and 20 were treated by closed method. Complications of hernia were higher (21%) in open method-treated cases than in closed method-treated cases (5%). Hernia recurred in three calves treated with open herniorrhaphy within 2 weeks of the procedure, with swelling in situ and muscular weakness at the site of operation. Shorter operation time and excellent healing rate (80%) were found in calves treated with closed herniorrhaphy. These findings suggest that the closed herniorrhaphy is better than the commonly-used open method for the correction of reducible umbilical hernia in calves.
Coculture of Bovine Chondrocytes with Demineralized Bone Matrix in Alginate Bead and Pellet Cultures
Bibek Chandra Sutradhar,홍경미,박진욱,최석화,김근형 한국임상수의학회 2010 한국임상수의학회지 Vol.27 No.2
Bio-integration of cartilage grafts with subchondral bone is a significant clinical challenge. To date, the use of demineralized bone matrix (DBM) has been one of the most effective strategies for bone cell proliferation in vivo. Here, we investigated whether coculture of chondrocytes and DBM could serve as a single-platform system containing all the essential elements for purposive bone and cartilage induction. The aim of this study was to evaluate and compare the phenotype and proliferation of bovine chondrocytes cocultured with DBM in two different culture systems, pellet and alginate bead culture. In alginate bead culture, we observed an increase in chondrocyte number and formation of cell clusters. Typical chondrocytic phenotype was maintained for entire eight weeks. Histological analysis showed that chondrocytes maintained a typical round, plump morphology and there was a gradual increase in lacunae. Both coculture systems yielded an expanded cell population as compared to the controls (chondrocytes alone). The production of glycosaminoglycans was also increased in the coculture systems as compared to controls.
Bibek Chandra Sutradhar,황야원,최석화,김근형 한국임상수의학회 2015 한국임상수의학회지 Vol.32 No.3
This study was designed in the fabricated poly (L-Lactic-co-ε-Caprolactone) (PLCL) scaffold using chitosanalginate hydrogel, which would be more suitable to maintain the biological and physiological functions continuing three dimensional spatial organizations for chondrocytes. As a scaffold, hydrogels alone is weak at endure complex loading within the body. In this study, we made cell hybrid scaffold constructs with poly (L-Lactic-co-ε-Caprolactone) (PLCL) scaffold and hydrogels to make a three-dimensional composition of cells and extracellular matrix, which would be a mimic of a native cartilage. Using a particle leaching technique with NaCl, we fabricated a highly-elastic scaffold from PLCL with 85% porosity and 300-500 μm pore size. A mixture of bovine chondrocytes and chitosan-alginate gel was seeded and compared with alginate as a control on the PLCL scaffold. The cell maturation, proliferation, extracellular matrix synthesis, glycosaminoglycans (sGAG) production and collagen type-II expressions were better in chondrocytes seeded in chitosan-alginate hydrogel than in alginate only. These results indicate that chondrocytes with chitosan-alginate gel on PLCL scaffolds provide an appropriate biomimetic environment for cell proliferation and matrix synthesis, which could successfully be used for cartilage repair and regeneration.
Gonhyung Kim , Ji-Hye Kim, Bibek Sutradhar, Seok Hwa Choi 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.2
Peripheral nerve injuries are very common in clinics and often result in severe functional deficits. The aim of this study was to evaluate the effect of treadmill running and electro-acupuncture on nerve regeneration and functional recovery of muscle activity following sciatic nerve crush injury in a rat model. A comparative study was conducted over 30 days on 60 adult male Sprague-Dawley rats grouped into sham control (C), electro-acupuncture (EA), treadmill (T), and treadmill plus electro-acupuncture (TEA). The left sciatic nerve was crushed for 30 sec using a hemostatic forceps and functional activity was evaluated with sciatic functional tests, nerve conduct velocity, muscle weight, and histology at 10, 20, and 30 days after injury. Muscle weight was significantly (P<0.05) increased between days 10 and 30 in the TEA group. In histology, the degree of damage was scored as C > TEA > T > EA, although necrosis and fibrosis of muscle was observed only in the TEA group. The EA and TEA groups showed rapid recovery with better myelinated axons on day 10. These results suggest that application of the TEA method with balanced exercise is a useful treatment option for peripheral nerve injury regeneration and muscle activity.
Preparation and Characterization of Anti-Scratch Polycarbonate Containing Acrylate Group
Jang, Hohyoun,Sutradhar, Sabuj Chandra,Ryu, Taewook,Choi, Kunyoung,Yoon, Sujin,Lee, Sungkwun,Kim, Whangi American Scientific Publishers 2017 Journal of Nanoscience and Nanotechnology Vol.17 No.10
<P>Polycarbonate copolymers containing valeric ester were synthesized from bisphenol A and valeric acid as the comonomer by the interfacial polymerization. The oligomer was synthesized from an aqueous bisphenol A and valeric acid in sodium hydroxide solution with solution of tetra butyl ammonium chloride (TBAC) in water (85%) as the phase transfer catalyst (PTC) and triphosgene in methylene chloride, followed by further reaction with triethylamine (TEA) to increase the molecular weight. The valeric acid groups were converted into the acrylate form by substitution reaction with iodomethane. The chemical structure and thermal properties of copolycarbonates were measured by H-1-NMR, thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). Moreover, the surface morphologies were assessed by atomic force microscopy (AFM), and the contact angle measurement of a sessile water drop onto the polymer firms was also performed. The hardness increased from 6B for linear polycarbonate to 45B grades of the copolymer films (100 mu m).</P>