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박인식,안상현,정재만,강윤호,이해풍,서귀문,홍용기,김호현,김진택 동국대학교 한의학연구소 1999 東國韓醫學硏究所論文集 Vol.7 No.2
본 연구는 긴볼레기말 추출물의 항고지혈증 효과를 조사하기 위해 ICR 생쥐에 TritonWR-1339(TX) 복강주사로 인위적인 고지혈증을 유발시킨 후 긴볼레기말 추출물(30㎎/㎏)를 복강주사하여 시간의 경과에 따른 간세포내에서의 지방 축적 변화를 조직화학적으로 관찰하였다. TX 주사후 그물구조의 세포질출 가진 간세포가 간엽 전체에서 관찰되었고, 일부 간소엽에서는 간세포 손상으로 인한 간세포판 소실이 나타났다. 또한 간세포내 지방축척도 증가하여 전체 간소엽의 간세포에서 지방의 과출현을 확인 할 수 있었고, 지방의 크기도 대조군에 비해 증가된 것으로 관찰되었다. 그러나 긴볼레기말 추출물 주사군에서는 그물구조의 세포질을 가진 간세포의 수가 TX 주사군에 비해 감소되었고, 대부분의 간소엽에서 정상적인 간세포판의 배열을 확인할 수 있었다. 간세포내의 지방 축적과 크기도 감소된 경향으로 관찰되었다. 이상의 결과로 볼 때 해조류 긴볼레기말 추출물은 고지혈증이 유발된 생쥐 간세포 내에서의 과도한 지방축적을 감소시키는 항고지혈증 효과를 하는 것으로 사료된다. Hepatic tissues of ICR mouse were intraperitoneally injeced with Colpomenia bullosa(CB) Extract after Triton WR-1339(TX) injection were observed to investigate the antihyperlipermic effect of CB extract for hyperlipidemic hepatic tissue caused by destruction of lipid metabolism. The hepatic tissues were obtained at hour-24, 48, and 72 after TX injection with CB extract treatment. And then these specimen were fixed in 10% neutral buffer solution and were cryocut. The tissue stained by H&E for general morphology and sudan black B for lipid distribution. The increase of hepatocyte having rneshlike cytoplasm were shown in all hepatic lobules after TX injection and the hepatic plates were disappeared in the region of meshlike hepatocyte aggregation, But the hepatocyte having meshlike cytoplasm were disappeared and hapatic plate were rearranged in CB extract injected mouse. The number of blue black colored lipid drop in hepatic cytoplasm of mouse injected with TX were increased and the size of lipid drop were enlarged. But the number of lipid drop in hepatic cytoplasm of mouse treated CB extract were decreased and the size of lipid drop were diminished. As results indicated that the accumulation of lipid drop caused by TX injection were mitigated by the antihyperlipidermic effect of CB extract.
마이크로 기공 알루미나 기판위에 스프레이 코팅된 ZnO 고정막의 광촉매 성질을 이용한 사진폐액으로 부터 Ag이온 회수
김홍식,안정민,박성 明知大學校 産業技術硏究所 2009 産業技術硏究所論文集 Vol.28 No.-
ZnO nanopowders were synthesized by solution combustion method(SCM) and their average particle size was about 30nm. They were immobilized on microporous alumina substrates by spray coating. The microporous alumina substrates were prepared by anodization and the average pore size was about 150nm. Ag ions were tried to be recovered from waste photograph developing solution by photocatalytic reaction. Three kinds of samples were prepared to compare their photocatalytic efficiency commercial ZnO powders (slurry type reaction), SCM ZnO powders immobilized on normal alumina substrates and SCM ZnO powders immobilized on anodized alumina substrates. The commercial ZnO powders without immobilization did not sbow any photocatalytic reaetion even though they have maximum surface area. This is probably ascribed to their poor cristalline quality. However, the Ag ions recovery rate by SCM ZnO powders immobilized on anodized alumina substrates was about 2.5 times higher than that by SCM ZnO powders immobilized on normal alumina substrates. This big difference in photocatalytic efficiency is probably due to the large surface area of the anodized alumina. This result was correspondent to photoluminescence measurement results.
다차선 고속도로 노면배수시설 개선방안연구 : L형측구 및 중앙분리대 집수정을 중심으로
김홍상,조강식 明知大學校 産業技術硏究所 1996 産業技術硏究所論文集 Vol.15 No.-
The road drainages that enables of the vehicle's fine operation and the road organization preservation are very important facilities. Especially, the functions of the road surface drainage facilities are critical for the safe driving in the rainy days. Normally, the expressway is designed by the vuilt-in-guide-lines and criteria. In the case of the design of multi-lane expressway, it is necessary to apply the different criteria from 4 lane expressway. Because the broaden road-surface of multi-lane expressway increase the drainage volume, the criteria of the 4 lane expressway can't be used to design of the multi-lane expressway. This paper is concentrated on the following improvement methods of the L-type ditch and the median barrier catch-pit that is directly related with the road surface d-rainage.
市內버스 交通事故 實態 및 豫防對策에 關한 硏究 : The Case of Urban Buses in Seoul 서울시 事故事例를 中心으로
김준식,김홍상 明知大學校 産業技術硏究所 1996 産業技術硏究所論文集 Vol.15 No.-
Urban buses have importance in the urban transit systems in our county, because of the easy access and low fare. But, until now the quality of transportation service don't satisfy the public transportation users need, and as the urban buses traffic accidents are three times the number of accidents, 1.4 times of the death and twice of the injured than suburban buses in the traffic accidents rate per 100 million vehicle-Km it threatened the basic safety to the urban public transportation. Therefore, this study analyzed actual traffic accidents condition of the urban buses into prevention of the urban buses traffic accidents. The most important thing is the efficient management system. To make this, the bus mutes arrangement based on the public interest and rational operation management are solved first of all. Furthermore, to prevent the traffic accidents of the urban buses making the practical use of analyzing data about actual condition of the accidents records management of the fleet are needed.
자연친화적 하천정비공법적용의 모니터링과 타당성검토 : 오산천을 대상으로
이상수,안성식,김진홍 中央大學校 建設環境硏究所 2002 環境科學硏究 Vol.13 No.2
본 연구에서는 오산천을 대상으로 하여 자연친화적 하천정비공법 내용을 조사하여 평가함으로써 공법 적용의 타당성을 검토하고 문제점 및 대안을 제시함으로써, 향후 다른 하천에도 자연친화적 하천정비사업을 적용할 수 있도록 지침을 제시하는데 참고가 되도록 하였다. 이를 위해 본 연구에서는 오산천유역의 자연적, 인위적 하상변동과 구조물의 상태를 정확히 조사·분석하여 자연친화적 하천정비공법의 적용에 따른 하상변동 및 공법의 수리적 안정성에 대한 영향을 파악하였다. 또한 오산천의 하상변동과 세굴 및 퇴적지점을 정기적으로 조사하여, 변동여부를 측정함으로써 자연형 하천공법의 적용에 대한 수리학적 안정성을 판단하여 공법의 적절성을 평가하였다. This study presents the hydraulic monitoring and the evaluation of the nature-friendly river works at the Osan River to estimate the applicability of the environmental river improvement works. For this purpose, the variation of the river bed including erosion and deposition and the hydraulic stability of the river works after applying the riverine technical construction methods were investigated. From the results of the hydraulic monitoring, the assessment on the applicability of the nature-friendly river works were performed.
김진택,최홍식,안상현,박인식,강윤호,김호현,이해풍 동국대학교 경주대학 1999 東國論集 Vol.18 No.-
Knee joint BALB/C mice were administered with JINTONGSAN(JTS) extract after Lipopolysaccaride(LPS) injection were observed to investigate the anti-inflammatiory effect of JTS for arthritis. The JTS extract(3.3 ㎖/㎏/day) were daily administered to mice suffered from arthritis of knee joint induced by LPS injection, as dose of 300㎖/㎏. The specimen were fixed in 4% paraformaldehyde and were decalcificate in EDTA solution for 4 Weeks. In synovial membrane, the hyperplasia of synovial lining cell(fibroblast like synoviocytes) on JTS group were diminished then LPS group. The number of synovial lining cell(synovial phagocytic cells) with filopodia and the infiltrated of lymphocyte on JTS group were decreased. In fibrous membrane, The region of fibrosis on JTS group were mitigated than LPS group and the appearance of fibroblast and migrated cell, as neutrophil leukocytes and lymphocyte, were decreased. As results indicated that JTS was effective in anti-inflammatory reaction for LPS-induced arthritis.
Applications on p-values of Chi-Square Distribution
Hong, Chong Sun,Hong, Sung Sick The Korean Statistical Society 2002 Communications for statistical applications and me Vol.9 No.3
In this paper, behaviors and properties of p-values for goodness-of-fit test are investigated. With some findings on the p-values, we consider some applications to determine sample size of a survey research using the regression equation based on a pilot study data. Regression equations are obtained by the well-known least squared method, and we find that regression lines could be formulated with only two data points, alternatively. For further studies, this works might be extended to t distributions for testing hypotheses about population mean in order to determine sample size of a prospective study. Also similar arguments could be explored for F test statistics.
COMPARISON STUDY OF BIVARIATE LAPLACE DISTRIBUTIONS WITH THE SAME MARGINAL DISTRIBUTION
Hong, Chong-Sun,Hong, Sung-Sick The Korean Statistical Society 2004 Journal of the Korean Statistical Society Vol.33 No.1
Bivariate Laplace distributions for which both marginal distributions and Laplace are discussed. Three kinds of bivariate Laplace distributions which are extended bivariate exponential distributions of Gumbel (1960) are introduced in this paper. These symmetrical distributions are compared with asymmetrical distributions of Kotz et al. (2000). Their probability density functions, cumulative distribution functions are derived. Conditional skewnesses and kurtoses are also defined. Their correlation coefficients are calculated and compared with others. We proposed bivariate random vector generating methods whose distributions are bivariate Laplace. With sample means and medians obtained from generated random vectors, variance and covariance matrices of means and medians are calculated and discussed with those of bivariate normal distribution.