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김현구,나경민,예수향,한호석 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.5
The present study was conducted to investigate extraction characteristics and antioxidative activity of Schiznadra chinensis extracts. Schiznadra chinensis was extracted by reflux extraction(RE) under different extraction conditions including solvent. The solid yield, turbidity, color value, titratable acidity, free sugar contents, electron donating ability(EDA) and superoxide dismutase(SOD)-like ability of Schiznadra chinensis extracts were determined. The highest solid yield value was obtained with water of 10 fold. No significant difference in turbidity and color value were found among the extracts prepared with various extraction solvents, 75% ethanol, 50% ethanol and water. The highest titratable acidity was obtained with water extracts of Schiznadra chinensis. The free sugar contents of Schiznadra chinensis extracted with water showed the highest value. Schiznadra chinensis extracts with water included higher contents of free sugar compared with those of the other solvent extracts, 50% ethanol and 75% ethanol extracts. The total polyphenol compound content of Schiznadra chinensis extracted with 50% ethanol showed the highest value. Schiznadra chinensis extracts with 50% ethanol included higher contents of total polyphenol compound compared with those of the other solvent extracts, water and 75% ethanol extracts. The electron donating ability of extracts were 60.87% in water, 57.24% in 50% ethanol, and 55.61% in 75% ethanol.
나경민,한호석,예수향,김현구 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.5
The present study was conducted to investigate extraction characteristics and antioxidative activity of Cassia tora L. extracts, Casia tora L. was extracted by reflux extraction under different extraction conditions including solvent. The solid yield, turbidity, color value, titratable acidity, free sugar contents, electron donating ability and superoxide dismutase-like ability of Cassia tora L. extracts were determined. The highest solid yield value was obtained with water of 10 fold. No significant difference in turbidity and color value were found among the extracts prepared with various extraction solvents, 75% ethanol, 50% ethanol and water. The highest titratable acidity was obtained with 50% ethanol of Cassia tora L.. The free sugar contents of Cassia tora L. extracted with water showed the highest value. Cassia tora L. extracts with water included higher contents of free sugar compared with those of the other solvent extracts, 50% ethanol and 75% ethanol extracts. The total polyphenol compound content of Cassia tora L. extracted with 50% ethanol showed the highest value. Cassia tora L. extracts with 50% ethanol included higher contents of total polyphenol compound compared with those of the other solvent extracts, water and 75% ethanol extracts.
Effect of red ginseng NaturalGEL on skin aging
Ye Hyang Kim,Hye Rim Park,So Yoon Cha,So Hun Lee,Jung Wung Jo,Jung Nam Go,Kang Hyuk Lee,Su Yeon Lee,Song Seok Shin 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.1
Background: In aged skin, degradation of collagen fibers, which occupy the majority of the extracellularmatrix in the dermis, and changes of aquaporin 3 (AQP3) and skin constituents, such as hyaluronic acidand ceramide, cause wrinkles and decrease skin moisturization to contribute to dryness and lowerelasticity skin. Red ginseng (RG) is used as a cosmetic and food material and is known to protect fromUVB-induced cell death, increase skin hydration, prevent wrinkles, and have an antioxidative effect. But,in general, RG used as a material is the soluble liquid portion in the solvent, and the part that is notsoluble in the solvent is discarded. Thus, we made the whole RG into microgranulation and dispersed inwater to produce gel form for using entire RG, and it was named red ginseng NaturalGEL (RG NGEL). Methods: RG NGEL was investigated for matrix metalloproteinases inhibitory activity, induction of Type Icollagen, AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrinexpression and compared with RG water extract. Results: RG NGEL reduced the levels of UV-induced matrix metalloproteinases and increased Type Icollagen in human fibroblast cells and upregulated AQP3, hyaluronan synthetase 2, serine palmitoyltransferase, ceramide synthase 3, and filaggrin expressions in human keratinocytes compared with RGwater extract. Conclusion: RG NGEL has the potential as an effective reagent for antiaging cosmetics to improve wrinkleformation and skin hydration.
Han, Ye Ri,Shim, Su-Hyang,Kim, Dong-Su,Jun, Chul-Ho THE AMERICAN CHEMICAL SOCIETY 2017 ORGANIC LETTERS Vol.19 No.11
<P>A new cascade double N-annulation method has been developed for the synthesis of benzoquinolizinium salts. The process takes place between allylamines, internal alkynes, and HBF4 in the presence of Rh(III)/Cu(II) complexes and leads to formation of multisubstituted benzoquinolizinium salts. Importantly, the resulting benzoquinolizinium salts serve as fluorescent materials whose emission wavelengths can be tuned by selection of appropriate substituents.</P>
In vitro and in vivo Anti-tumor Effects of Oriental Herbal Mixtures
박계원,Su-hyang Ye,Young-jun Kim,So-Ra Jung,Min-hyuk Bang,이한웅,박기문 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.4
To identify antitumor materials, oriental herb extracts were investigated in the present study. The effects of individual oriental herb extracts (OHE) and a mixture of these extracts (MOHE) for antioxidant, free radical scavenging,and tumoricidal activities were determined. The OHEs and MOHE exhibited relatively high free radical scavenging and antioxidant activities, in a concentration dependent manner. The total phenolic contents of the extracts suggest that these compounds may have played a role, at least in part, in the free radical scavenging and antioxidant effects. Since the MOHE showed the highest toxicity against tumor cell lines, the MOHE was administrated in cancer mice models. Consistent with the in vitro studies, the MOHE resulted in prolonged life spans in cancer mice possibly by combination of its anticancer and antioxidant activities. Our data indicate the possibilities of using the MOHE to counteract carcinogenesis as well as other forms of electrophilic toxicity.
Effect of red ginseng NaturalGEL on skin aging
Kim, Ye Hyang,Park, Hye Rim,Cha, So Yoon,Lee, So Hun,Jo, Jung Wung,Go, Jung Nam,Lee, Kang Hyuk,Lee, Su Yeon,Shin, Song Seok The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.1
Background: In aged skin, degradation of collagen fibers, which occupy the majority of the extracellular matrix in the dermis, and changes of aquaporin 3 (AQP3) and skin constituents, such as hyaluronic acid and ceramide, cause wrinkles and decrease skin moisturization to contribute to dryness and lower elasticity skin. Red ginseng (RG) is used as a cosmetic and food material and is known to protect from UVB-induced cell death, increase skin hydration, prevent wrinkles, and have an antioxidative effect. But, in general, RG used as a material is the soluble liquid portion in the solvent, and the part that is not soluble in the solvent is discarded. Thus, we made the whole RG into microgranulation and dispersed in water to produce gel form for using entire RG, and it was named red ginseng NaturalGEL (RG NGEL). Methods: RG NGEL was investigated for matrix metalloproteinases inhibitory activity, induction of Type I collagen, AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrin expression and compared with RG water extract. Results: RG NGEL reduced the levels of UV-induced matrix metalloproteinases and increased Type I collagen in human fibroblast cells and upregulated AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrin expressions in human keratinocytes compared with RG water extract. Conclusion: RG NGEL has the potential as an effective reagent for antiaging cosmetics to improve wrinkle formation and skin hydration.
Physiological Activities of Garlic Extracts as Affected by Habitat and Solvents
김현구,Su-Hyang Ye,Tae-Soo Lim,하태열,권중호 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.4
Physiological activities of Korean-grown garlic (GKG) and Chinese-grown garlic (GCG) were examined. Ni-trite-scavenging activity (NSA), superoxide dismutase (SOD)-like activity, and electron-donating ability (EDA) of garlic ex-tracted with water or with either 50% or 100% ethanol were measured. NSA was optimized at pH 1.2 and was highest in wa-ter and 50% ethanol extracts of both origins. SOD-like activities of water or 50% ethanol extracts from both Korea and Chinawere 48.4363.89% lower than those of 1% or 0.1% L-ascorbate solutions. SOD-like activities of GKG extracts were higherthan those of GCG extracts, and those of water extracts of samples were highest. EDAs of GKG extracts were higher(32.5143.74%) than those of GCG extracts, while those of both sample extracts were lower than 1% or 0.1% L-ascorbate so-lutions.