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      • 정신적 곤혹과 기업정신체계의 확립

        齊善鴻 啓明大學校 産業經營硏究所 2002 經營經濟 Vol.35 No.2

        인간은 정신이 있으며 인간이 하는 일은 정신적 동력을 필요로 한다. 이 점에 대해서는 이미 질문할 필요가 없다. 그러나 우리는 하나의 물질적인 유혹을 막을 수 없는 시대에 처해 있다. 기업 또한 이러한 배경에서 자신의 사업을 전개하고 있다. 그러나 현실은 물질적 자극, 상급이 하급에 대한 관리, 제도관리 등 전통적인 사상과 방법을 주도로 하는 관리모델이 이미 객관효과에서 엄중한 문제를 발생하였음을 나타낸다. 물질적인 자극은 인간의 끝없는 욕망을 자극하였다. 그러나 인간은 조직에서 이러한 만족을 얻을 수 없다. 상급이 하급을 관리하는 하나의 단조로운 관리관계는 사람의 주체성을 직접 저촉하였으며 인성에서 가장 심각한 반항을 초래시켰다. 제도관리는 소수의 엘리트들의 의지(아마도 호의적인 것이지만 독선적인 것)를 사람들에게 강요하여 사람들의 정감독립성을 저촉하여 "호의가 나쁜 일을 빚어내는" 결과가 되고 만다. 기업은 하나의 군중의 집합체이며 또한 하나의 집결된 인격을 필요로 하는데 이것이 바로 기업의 정신체계이다. 자본주의의 발전, 자본주의의 정신의 공로는 지워버릴 수 없다. 자본주의의 문제 또한 정신적인 편이(偏移)에 뿌리를 박고 있다. 동방국가는 서방국가의 종교적 배경이 없으며 역사, 현실과 미래를 통일시키려는 사람들의 일종의 정신체계가 결핍하다. 이것이 바로 문제의 근본이다. 더욱 엄중한 것은 동방사람들에 서방관리를 배우고서 그것을 마치 성경처럼 받들고 있다. 그러나 우리에게는 선방관리의 유효성을 받쳐 주는 문화적 토양이 결핍하다. 게다가 우리는 아직 자신의 사상관리체계와 이론을 발전시키지 못하였다. 우리의 미래는 우리의 새로운 관리사상에 대한 창조와 확립에 의해 결정될 것이다. it's doubtless that everyone has his own spirit, which motivates his behavior. While we are living in an age full of material temptation, our management has to be based on such a circumstance. However, it has been proved that serious problems have been caused by the management patterns based on traditional thinking and methodology. Such patterns include material incentive, hierarchical management, institutional management, etc. People's desire for materials, which is aroused by the material incentives, will never be fulfilled in the organization; the monotonous hierarchical management pattern, which threatens the individuality of the people, has led to intense rebellion in human nature; the institutional management, imposing the intentions of a few people on others, violates the emotional independence of the people. As a collective body of people itself, the enterprise requires a collective personality - the spirit system. The development of capitalism owes much to capitalist spirit. The problems of capitalism are also rooted in the shift of the spirit. As the oriental system integrating the history, reality and future has not been established in such countries yet. This in fact is the essence of the problem. What is more, while the oriental people introduced western management patterns, they took it for granted that these patterns were perfect. However, not only is the cultural background required by the western management patterns not available, but no new management thoughts or theories has been established in the oriental countries yet. To a great extent, the future of such countries depends on the establishment of new management thoughts.

      • A 200A, 1200V LIGHT TRIGGERED TRIAC

        Qi, Zheo Shan,Jun, Wu,San, Gao Ding 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1

        This paper proposes a new light triggered triac structure with a center cone-shape groove light sensitive gate, and describes structure features and key manufacturing techniques of this device. A 200A, 1200V, 30㎜ dia, light triggered triac has been developed. This device has the characteristics of the minimum light triggered current of less than 100mA, the on-state voltage of less than 1.5V, the commutating dv/dt capability of more than 100V/㎲ and the commutating di/dt capability of more than 50A/㎲.

      • KCI등재

        Cough Inhibition Activity of Schisandra chinensis in Guinea Pigs

        Shan Zhong,Li-Ping Bai,Xiao-Dong Liu,Die-Yi Cai,Lee-Fong Yau,Chu-Qin Huang,Jia-Qi Zhang,Ke-Fang Lai,Nan-Shan Zhong 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.4

        Chronic cough is very common in respiratory clinics, and no effective drugs are available. Schisandra chinensis (Turcz.) Baill. (S. chinensis), an important traditional Chinese medicine, has been extensively prescribed for patients with a persistent cough. Preliminary research indicated that 95% ethanol extracts (EE) of S. chinensis showed remarkable antitussive activity in guinea pigs exposed to cigarette smoke (CS). To find out the antitussive ingredients of S. chinensis, EE was divided into four fractions according to the polarity: petroleum ether extract (PEE), ethyl acetate extract (ECE), n-butyl alcohol extract, and residue extract. The antitussive, antioxidant, and anti-inflammatory effects of the four fractions were evaluated in a guinea pig model of cough hypersensitivity induced by CS exposure. Eighteen main constituents of the two effective fractions, PEE and ECE, were identified using ultra-high-pressure liquid chromatography electronic spray ion time-of-flight mass spectrometry. The cough inhibition activities of compound 1, 3, 9, 10, 17 were evaluated on citric acid induced acute cough guinea pigs. The results showed that the antitussive activity of EE was almost all contained in PEE and ECE. The 16 major peaks in PEE were identified as 15 lignans (1–12 and 14–16) and 1 triterpene (compound 13), and 3 major peaks (1, 17, and 18) in ECE were also identified as lignans. Three doses of five compounds brought about a significant decrease in number of cough efforts (P < .01), and the cough inhibition rates were between 40.9% and 85.1%. Therefore, lignans are the antitussive ingredients of S. chinensis.

      • KCI등재

        Higher-level Production of Ascomycin (FK520) by Streptomyces hygroscopicus var. Ascomyceticus Irradiated by Femtosecond Laser

        Hai-shan Qi,Xing Xin,Shan-shan Li,Jian-ping Wen,Yun-lin Chen,Xiao-qiang Jia 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.4

        Femtosecond laser irradiation technology was employed for the first time to improve the ascomycin (FK520)yield of Streptomyces hygroscopicus var. ascomyceticus NT2-11, which is an N-methyl-N-nitro-N-nitrosoguanidine (NTG)-induced strain derived from S. hygroscopicus (ATCC14891). The mutant FS35 with high and stable FK520 production capacity was then obtained in the optimal irradiation conditions (25 mW for 6 min) by the Titanium sapphire laser system (810 nm, 76 MHz, 150 fs). The FK520 production capacity of FS35 was 45% higher than that of the parental strain NT2-11. Moreover, under the optimal fermentation conditions, FK520 fermentation titer of FS35 reached 300 mg/L and the intrinsic kinetics of FS35 and NT2-11 were investigated comparatively in 3phases. The mathematical models provided a good description of FK520 fermentation process for both strains and valuable information for optimizing operation and pilotplant enlargement research. The comparative studies on parameters of the models confirmed the advantages in production and the decrease of substrate inhibition through femtosecond laser irradiation. Therefore, femtosecond laser irradiation provides a promising way to enhance the production of FK520 in S. hygroscopicus. Femtosecond laser irradiation technology was employed for the first time to improve the ascomycin (FK520)yield of Streptomyces hygroscopicus var. ascomyceticus NT2-11, which is an N-methyl-N-nitro-N-nitrosoguanidine (NTG)-induced strain derived from S. hygroscopicus (ATCC14891). The mutant FS35 with high and stable FK520 production capacity was then obtained in the optimal irradiation conditions (25 mW for 6 min) by the Titanium sapphire laser system (810 nm, 76 MHz, 150 fs). The FK520 production capacity of FS35 was 45% higher than that of the parental strain NT2-11. Moreover, under the optimal fermentation conditions, FK520 fermentation titer of FS35 reached 300 mg/L and the intrinsic kinetics of FS35 and NT2-11 were investigated comparatively in 3phases. The mathematical models provided a good description of FK520 fermentation process for both strains and valuable information for optimizing operation and pilotplant enlargement research. The comparative studies on parameters of the models confirmed the advantages in production and the decrease of substrate inhibition through femtosecond laser irradiation. Therefore, femtosecond laser irradiation provides a promising way to enhance the production of FK520 in S. hygroscopicus.

      • KCI등재

        Bioactivity of essential oil of Litsea cubeba from China and its main compounds against two stored product insects

        Kai Yang,Cheng FangWang,Chun Xue You,Zhu Feng Geng,Rui Qi Sun,Shan Shan Guo,Shu Shan Du,Zhi Long Liu,Zhi Wei Deng 한국응용곤충학회 2014 Journal of Asia-Pacific Entomology Vol.17 No.3

        During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oilof Litsea cubeba fruits was found to possess strong contact toxicity against the cigarette beetle Lasiodermaserricorne adults and the booklouse Liposcelis bostrychophila, with LD50 values of 27.33 μg/adult and71.56 μg/cm2, respectively, and also showed strong fumigant toxicity against the two stored product insectswith LC50 values of 22.97 and 0.73 mg/L, respectively. The essential oil obtained by hydrodistillation wasinvestigated by GC MS. The main components of the essential oil were identified to be E-citral (geranial)(27.49%), Z-citral (neral) (23.57%) and D-limonene (18.82%) followed by β-thujene (3.34%), β-pinene (2.85%), α-pinene (2.57%), 6-methyl-5-hepten-2-one (2.40%) and linalool (2.36%). Citral (Z/E-citral), D-limonene, β-pinene,α-pinene and linalool were separated and purified by silica gel column chromatography and preparative thinlayer chromatography, and further identified by means of physicochemical and spectrometric analysis. Citral andlinalool showed strong contact toxicity against L. serricorne and L. bostrychophila (LD50 = 11.76, 12.74 μg/adultand 20.15, 99.97 μg/cm2, respectively) and fumigant toxicity against L. serricorne and L. bostrychophila (16.54,18.04 mg/L air and 0.14, 0.71 mg/L air, respectively). Otherwise, citral, D-limonene and linalool were strongly repellentagainst the cigarette beetle L. serricorne as the essential oil whereas β-pinene and α-pinene exhibited weakerrepellency against the cigarette beetle compared with the positive control, DEET. Moreover, except α-pinene andlinalool, the other three compounds as well as the essential oil exhibited comparable repellency against thebooklouse relative to DEET.

      • Decreased Expression of LKB1 Correlates with Poor Prognosis in Hepatocellular Carcinoma Patients Undergoing Hepatectomy

        Huang, Yue-Han,Chen, Zhen-Kun,Huang, Ka-Te,Li, Peng,He, Bin,Guo, Xu,Zhong, Jun-Qiao,Zhang, Qi-Yu,Shi, Hong-Qi,Song, Qi-Tong,Yu, Zheng-Ping,Shan, Yun-Feng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

        Aim: To study any correlation of LKB1 expression with prognosis in hepatocellular carcinoma (HCC) cases. Methods: A total of 70 HCC patients and 20 primary intrahepatic stone patients in the first affiliated hospital of Wenzhou Medical College were enrolled in this study. LKB1 expression was detected by immunohistochemistry. Patients were followed-up and prognostic factors were evaluated. Result: LKB1 expression was decreased in the HCC samples. Loss of LKB1 expression in HCC was significantly related to histologic grade (P=0.010), vascular invasion (P=0.025) and TMN stage (P=0.011). Patients showing negative LKB1 expression had a significantly shorter disease-free and overall survival than those with positive expression (P = 0.001, P=0.000, respectively). Multivariate Cox regression analysis indicated that LKB1 expression level was an independent factor of survival (P = 0.033). Conclusion: HCC patients with decreased expression LKB1 have a poor prognosis. The loss of LKB1 expression is correlated with a lower survival rate.

      • KCI등재

        Study on the Influence of the Language Symbols on Side-Scrolling Puzzle Games - Focused on the Players' Empathy

        Qi Yi,Xinyi Shan,Jeanhun Chung 한국인터넷방송통신학회 2023 International Journal of Internet, Broadcasting an Vol.15 No.1

        According to whether language symbols are used to solve puzzles, puzzle games can be roughly divided into puzzle games with language symbols and puzzle games without language symbols. Puzzles games with language symbols can be subdivided into dialogue puzzles games and word puzzles games. These different puzzle-solving methods have different characteristics and have different effects on the empathy in the game. In horizontal scrolling games, due to the characteristics of the third-person perspective of horizontal scrolling games, there is always a ‘fourth wall’ between the player and the controlled character, making it difficult for players to gain a empathy when playing such games .Especially when there is a dialogue between a player-controlled character and an NPC, the sense of distance between the player and the character will be further amplified. As one of the most common game types in side-scrolling games, side-scrolling puzzle games can be divided into language symbols-based puzzle game and non-language symbols-based puzzle game according to whether language symbols are used to solve puzzles, and then promote the development of the game plot. We combine the characteristics of horizontal scrolling games, and analyze the influence of language symbols on empathy in puzzle-solving games by summarizing the game characteristics of two different puzzle-solving methods. The results show that in horizontal scrolling puzzle games, solving puzzles without using language symbols can better expand the player's sense of plot substitution.

      • KCI등재

        Endovascular Repair of Blunt Popliteal Arterial Injuries

        Shan Zhong,Xiquan Zhang,Zhong Chen,Peng Dong,Yequan Sun,Wei Zhu,Xiaolin Pan,Deming Qi 대한영상의학회 2016 Korean Journal of Radiology Vol.17 No.5

        Objective: To evaluate the feasibility and effectiveness of endovascular repair for blunt popliteal arterial injuries. Materials and Methods: A retrospective analysis of seven patients with clinical suspicion of popliteal arterial injuries that were confirmed by arteriography was performed from September 2009 to July 2014. Clinical data included demographics, mechanism of injury, type of injury, location of injury, concomitant injuries, time of endovascular procedures, time interval from trauma to blood flow restoration, instrument utilized, and follow-up. All patients were male (mean age of 35.9 ± 10.3 years). The type of lesion involved intimal injury (n = 1), partial transection (n = 2), complete transection (n = 2), arteriovenous fistula (n = 1), and pseudoaneurysm (n = 1). All patients underwent endovascular repair of blunt popliteal arterial injuries. Results: Technical success rate was 100%. Intimal injury was treated with a bare-metal stent. Pseudoaneurysm and popliteal artery transections were treated with bare-metal stents. Arteriovenous fistula was treated with bare-metal stent and coils. No perioperative death and procedure-related complication occurred. The average follow-up was 20.9 ± 2.3 months (range 18–24 months). One patient underwent intra-arterial thrombolysis due to stent thrombosis at 18 months after the procedure. All limbs were salvaged. Stent migration, deformation, or fracture was not found during the follow-up. Conclusion: Endovascular repair seems to be a viable approach for patients with blunt popliteal arterial injuries, especially on an emergency basis. Endovascular repair may be effective in the short-term. Further studies are required to evaluate the long-term efficacy of endovascular repair.

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