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Chang, Oliver,Choi, Eun-Kyung,Kim, Im-Ryung,Nam, Seok-Jin,Lee, Jeong Eon,Lee, Se Kyung,Im, Young-Hyuck,Park, Yeon Hee,Cho, Juhee Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20
Background: Breast cancer patients experience a variety of altered appearance - such as loss or disfigurement of breasts, discolored skin, and hair loss - which result in psychological distress that affect their quality of life. This study aims to evaluate the impact of socioeconomic status on the altered appearance distress, body image, and quality of life among Korean breast cancer patients. Materials and Methods: A cross-sectional survey was conducted at advocacy events held at 16 different hospitals in Korea. Subjects were eligible to participate if they were 18 years of age or older, had a histologically confirmed diagnosis of breast cancer, had no evidence of recurrence or metastasis, and had no psychological problems at the time of the survey. Employment status, marital status, education, and income were assessed for patient socioeconomic status. Altered appearance distress was measured using the NCI's cancer treatment side effects scale; body image and quality of life were measured by the EORTC QLC-C30 and BR23. Means and standard deviations of each outcome were compared by socioeconomic status and multivariate linear regression models for evaluating the association between socioeconomic status and altered appearance distress, body image, and quality of life. Results: A total of 126 breast cancer patients participated in the study; the mean age of participants was 47.7 (SD=8.4). Of the total, 83.2% were married, 85.6% received more than high school education, 35.2% were employed, and 41% had more than $3000 in monthly household income. About 46% had mastectomy, and over 30% were receiving either chemotherapy or radiation therapy at the time of the survey. With fully adjusted models, the employed patients had significantly higher altered appearance distress (1.80 vs 1.48; p<0.05) and poorer body image (36.63 vs 51.69; p<0.05) compared to the patients who were unemployed. Higher education (10.58, standard error (SE)=7.63) and family income (12.88, SE=5.08) was positively associated with better body image after adjusting for age, disease stage at diagnosis, current treatment status, and breast surgery type. Similarly, patients who were married and who had higher education had better quality of life were statistically significant in the multivariate models. Conclusions: Socioeconomic status is significantly associated with altered appearance distress, body image, and quality of life in Korean women with breast cancer. Patients who suffer from altered appearance distress or lower body image are much more likely to experience psychosocial, physical, and functional problems than women who do not, therefore health care providers should be aware of the changes and distresses that these breast cancer patients go through and provide specific information and psychosocial support to socioeconomically more vulnerable patients.
뇌열환자에서 임상증상과 영상소견과의 관계 : Correlation of Clinical Outcome with Imaging Findings
박세혁,조용준,이규호,오세문 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.12
Schizencephaly is an infrequent congenital disorder of neuronal migration characterized by gray matter-lined clefts that extend through the entire cerebral hemisphere, from the ependymal lining of the lateral ventricle to the pial covering of the cortex. We have studied seven patients with schizencephaly rstrospectively to correlate clinical outcome with the type, size, and location of the clefts and to find associated brain anomalies. Three patients had bilateral clefts(one with two open lip clefts and the other two with a left open lip cleft and a right closed lip cleft), another two patients had left unilateral open lip clefts, and the rest two patients had right closed lip clefts. Clinically these patients presented motor dysfunction such as hemiparesis, seizures, and variable developmental delay. Patients with bilateral clefts, paticularly open lip type had worse motor and developmental impairment than those with unilateral clefts. Patient with unilateral medium open lip cleft had worse motor and intellectual impairment than those with unilateral closed lip clefts or small open lip cleft. All patients with f개ntal lobe involvement had motor dysfunction. Absence of septum pellucidum, gray matter heterotopia, polymicrogyria, and hypoplasia of optic nerves were also frequently found to be associated with schizencephaly. Three patients with skull changes such as enlargement of the hemicranium of erosion of the inner table of the skull were shunted but only one patient improved in the imaging study We conclude that the severity of patient's symptoms is related to the amount type and location of the involved brain.
Mixed Model에 의한 학교효과 평가 방법의 탐색
임 시 혁 공주교육대학교초등교육연구원 2015 敎育論叢 Vol.52 No.2
In this paper, the methods of appling SPSS Mixed models to School effect assessment methods, one of the major appling area of multilevel models were shown. Even though SPSS Mixed Models are not excusive for multilevel models and less convenient than multilevel specialized programs, it was shown that they can be used for modeling and analysing school effect. 학교효과를 평가하기 위한 다층모형 분석에서 다층모형 전용 프로그램이 아닌 범용 프로그램인 SPSS의 Mixed Models을 이용하여 모형을 설정하고 분석하는 방법론을 탐색하였다. 전용 프로그램보다 모형설정 과정이 개념적으로 이해하기가 불편하지만 SPSS의 Mixed Models로도 다층모형을 설정하여 학교효과를 추정할 수 있음을 보여 주었다.
뇌동맥류환자에서의 나선식 CT를 이용한 3D CT 혈관조영술의 이용 및 가치
박세혁,이규호,오세문 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.11
We evaluate the detection of cerebral aneurysms with 3-dimensional(3D) computed tomographic angiography(CTA) and compare the results with those of magnetic resonance angiography(MRA) and conventional cerebral angiography(CCA). Ten patients with 12 cerebral aneurysms were studied with spiral CT in conjunction with CCA and MRA. All aneurysms(3-20㎜ in diameter) were seen in CTA, MRA and CCA except 1 aneurysm(3㎜ in diameter) in MRA. CIA demonstrated neck, shape, direction of the aneurysm, and adjacent vascular and bony structures well. Of 12 aneurysms. 4 were seen equally with CCA and MRA. 4 were seen better with CCA owing to flow-related or motion artifact in MRA, and 4 were seen better with MRA. CTA was considered to be superior to CCA and MRA in demonstrating calcification and thrombosis in the aneurysm. 3D CTA with spiral CT is a rapid noninvasive method of visualizing the cerebral aneurysms and is comparable with MRA in demonstrating the aneurysms. We think 3D CTA can be a screening tool for use in the patients with suspected cerebral aneurysms and will be of a value in surgical planning for patients with complex cerebral aneurysms, in demonstrating the anatomy of the aneurysms and surrounding structures.
박세혁,윤대영,이규호,오세문 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.7
Technical advances in computer image analysis have made possible three-dimensional(3D) surface reformations of anatomic structures from contiguous axial CT slices We have recently utilized this 3D CT reconstruction with spiral CT scanner in S consecutive patients with primary or secondary craniosynostosis to assess the pres-ence and extent of synostosis. associated calvarial deformity and to facilitate surgical planning of ths craniectomy sits High resolution 3- mm contiguous CT sections were obtained and 3D shaded-surface reconstruction image gen-erated after reformation at f- mm interval In each case 9D CT demonstrated the exact extent of synostosis. and in 3 cases it was confirmed by surgical inspection 3D CT lmages facilitated surgical planning by precisely localizing the proper sits for craniectomy Three-dimensional CT with shaded-surface display may be a us㉣ful adjunct to im-aging and surgical planning in the patients with craniosynostosis. as well as a useful follow-up imaging study during observation or after surgery
Hyuck-Se Kwon,Jun Hong Park,Yang-Seok Oh,Hyun-Kyung Shin,Sang-Jae Park,Byung-Sik Gang,Jae-Gun Park,Jin-Kyung Kim 한국실험동물학회 2006 Laboratory Animal Research Vol.22 No.4
The ethanol extracts from bark of red pine, Pinus densiflora Siebold et Zuccarini, was examined for single-dose and seven-day repeated-dose toxicity with Sprague-Dawley rats. The single oral dose of the extracts at 5000 ㎎/㎏ did not produce mortality or abnormal gross appearance of the internal organs of rats. In seven-day repeated-dose toxicity study, the extracts administered at doses of 100, 1000, or 5000 ㎎/㎏ for 7 days. There were no significant changes of body weights and organ weights during the experimental period. Hematological analysis and clinical blood chemistry have no revealed toxicity effect of the ethanol extracts from bark of Pinus densiflora. Pathologically, neither gross abnormalities nor histopathological changes observed between controls and treated rats both sexes. Collectively, these data suggest that the ethanol extracts from bark of Pinus densiflora have a high margin of safety.