경북 성주지역 장수노인의 영양상태(Ⅰ)

백지원(Baek, Ji-Won),구보경(Koo, Bo-Kyung),김규종(Kim, Kyu-Jong),이연경(Lee, Yeon-Kyung),이성국(Lee, Sung-Kook),이혜성(Lee, Hye-sung) 한국영양학회 2000 Journal of Nutrition and Health Vol.33 No.4

경북 성주지역 장수노인의 계절별 식품섭취 상태

백지원(Ji-Won Baek),구보경(Bo-Kyung Koo),김규종(Kyu-Jong Kim),이연경(Yeon-Kyung Lee),이성국(Sung-Kook Lee),이혜성(Hye-Sung Lee) 한국식품영양과학회 2000 한국식품영양과학회지 Vol.29 No.4

본 연구는 우리나라 장수노인들의 식품섭취상태를 분석 평가하고 건강한 장수를 위한 식생활 지침의 설정을 위한 기초자료를 얻고자 수행되었다. 연구 대상은 경상북도 성주군에 거주하는 85세 이상 고령노인 중에서 일상 생활에 문제가 없는 224명이었으며 이들을 대상으로 반복 24시간 회상법을 이용하여 1년간 4회의 계절별 식품 섭취 조사를 실시하였으며 결과를 요약하면 다음과 같다. 계절별 식품군별 섭취량에 있어서 남자노인은 감자류의 섭취량이 여름철에 유의적으로 높고, 버섯류의 섭취량이 가을철에 유의하게 높은 것을 제외하고는 모든 식품군의 섭취량에 있어 계절별 차이가 나타나지 않았다. 여자노인의 경우 곡류, 당류, 두류, 채소류, 과일류, 조미료류, 음료 및 주류, 육류, 우유류, 어패류의 섭취량이 겨울철에 유의하게 높았으며, 종실류, 해조류, 난류의 섭취량은 계절에 따른 차이가 없었다. 조사 대상자들의 연평균 1일 총 식품 섭취량은 594.4±186.1 g이었으며 이 중에서 513.5±161.2 g(86.4%)는 식물성 식품군으로부터 섭취하였고 79.3±56.7 g(13.3%)는 동물성 식품군으로부터 섭취하였다. 섭취량이 가장 높았던 식품군은 곡류였으며그 다음이 채소류, 과일류, 어패류, 음료 및 주류, 조미료류, 두류, 육류, 우유류, 감자류 등의 순이었다. 장수 노인대상자들의 음식별 섭취빈도는 밥류에 있어서는 쌀밥의 섭취비율이 80.1~89.2%로 가장 높았으며 국과 찌개류에서는 쇠고기국, 된장국, 된장찌개의 섭취 비율이 높았다. 어육류 식품의 경우 조기구이의 섭취비율(9.4~12.7%)이 높았으며, 해조류 식품의 경우 김구이의 섭취비율(7.4~20.5%)이 높았고, 각 계절마다 계절식품의 섭취비율이 높았다. 김치류의 경우 배추김치의 섭취비율이 4계절 모두 70% 이상으로 높게 나타났다. 일품요리류는 손쉽게 조리할 수 있는 라면과 국수의 섭취비율이 높았다.<br/> 본 연구의 결과에서 경북 성주지역 장수 노인들의 계절별 식품 섭취량에 있어 겨울철의 식품 섭취량이 다른계절에 비해 유의하게 높았으며, 남자노인보다는 여자노인이 식품섭취에 계절에 의한 영향을 더욱더 많이 받는 것으로 나타났다. 또한 장수 노인들은 가공식품보다는 계절마다 제철에 생산되는 자연 식품의 섭취비율이 높았다. 전반적으로 장수노인들은 소식의 경향을 보였으며 이와 같은 소식습관과 신선한 식물성 식품들의 일상 섭취가 건강한 장수에 영향을 미쳤을 가능성도 있을 것으로 사료된다. The purpose of this study was to estimate food intakes of the long-lived elderly and to obtain the data for establishing dietary guidelines that may be recommended for the general population for the sake of longevity. The subjects of the study were 224 elderly people of age over 85 years living in Kyungpook Sung-Ju area who have no problem in daily living. The food consumption survey was carried out seasonally by the repeated 24-hr recall method for one year. The subject group for this study was composed of 58 males and 166 females, the average age being 87 years old. Food intakes of the winter were more than any other seasons. The mean daily total food intake per capita was 594.4 g, 513.5 g (86.4%) from plant foods and 79.3 g (13.3%) from animal foods. The sequence of high intakes of food groups were cereals, vegetables, fruits, fishes, legumes and meats. Boiled white rice, beef soup, soybean paste soup, soybean paste stew, broiled yellow croaker, kimchi, ra myon and broiled noodles were consumed most frequently. In conclusion, the subjects consumed much more plants foods than animal foods and consumed more natural and seasonal foods than processed foods and also showed food habits of eating small meals. Dietary habits of eating small meals containing abundant amount of fresh plant foods might partially contribute to the longevity of the subjects.

Experimental Study on the Deodor and Suppression of Heavy Metal Elution from Sewage Sludgs Solidification

( Sang Rae Lee ),( Keun Jae Lee ),( Ja Sul Koo ),( Nam Goo Moon ),( Tae Hwan Son ),( Byung Hwa Lee ) 한국폐기물자원순환학회(구 한국폐기물학회) 2011 한국폐기물자원순환학회 추계학술발표논문집 Vol.2011 No.-

P085 : Objective analysis of poly-L-lactic acid (PLLA) injection efficacy in different setting

( Sang Young Byun ),( Jung Won Shin ),( Soon Hyo Kwon ),( Koo Il Seo ),( Mi Sook Park ),( Joshua Lee ),( Kyoung Chan Park ),( Jung Im Na ),( Chang Hun Huh ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Background: A Poly-L-lactic acid (PLLA) is a soft tissue filler known to stimulate collagen production. Objectives: The purpose of this study is to analyze objective volumetric effect of PLLA in different setting of injection schedule on the cheek. Methods: A split-face, evaluator-blind randomized study in 24 volunteers was conducted. One side was injected 3 times with dose of 4cc per visit at week 0, 4, and 8, and the other side was injected 2 times with dose of 6cc per visit at week 4 and 8, respectively. Volunteers were evaluated with facial volume loss scale (FVLS) from 1 to 5(most severe) and objective volumetric values using Vectra-CR 3D camera system. Results: Improvement of FVLS was statistically significant (p<0.05) and maintained until 12 months in both injection side. Vectra showed volumetric difference (cc) between before and after injection. In 3 times injection side, it was increased from 2.12cc (after 1 month) to 3.17cc (after 12 months). In 2 times injection side, it was increased from 2.26cc (after 1 month) to 3.19cc (after 12 months). Gradual volumetric improvement over 12 months was statistically significant in both sides (P<0.05, generalized linear model). There was not statistically significant difference between three and two times injection side in both FVLS and Vectra. There was no severe adverse event. Conclusion: PLLA filler has continuous volumetric effect and there was not a significant difference by injection times at the same total injection volume.

전파천문관측용 400MHz 광-대역 상관기 보드의 설계 및 제작

Lee, Chang-hoon,Park, Han-Kyu,Kim, Kwang-Dong,Koo, Bon-Chul,Byun, Do-Young,Han, Seog-Tae,Kim, Tae-Sung 대한전자공학회 2004 電子工學會論文誌-SC (System and control) Vol.41 No.2

본 논문에서는 전파천문 분야에서 특이한 전파원의 서베이 연구나, 외부은하의 스펙트럴 선 관측연구에 필요한 자기상관분광기 형태의 광-대역 전파분광기 제작에 있어서 가장 핵심적인 역할을 하는 상관기 보드를 설계, 제작하였다. 본 연구에서는 미국 국립천문대(NRAO)에서 개발된 QUAINT 상관기 칩을 사용하여 최대 100 ㎒의 동작 속도로 최대 400 ㎒ 대역폭을 갖는 중간주파수 신호를 분광할 수 있는 상관기 보드를 설계, 제작하였다. 제작된 상관기 보드의 성능시험을 위해 1.67 ㎒와 0.5 ㎒의 구형파를 인가하여 자기상관계수를 구하고, FFT를 취한 결과 이론적인 상관결과와 거의 같은 결과를 얻었다. In this paper, we performed the design and the development of the wide-band correlation board to be an important role in the autocorrelation spectrometer's building for the observation study of an extra-galaxy's spectral lines and the survey research of the special radio sources in field of the radio astronomy. In this research, the developed correlation board by using QUAINT correlator chip(made by NRAO) has maximum 100 MHz clock speed and operate at a intermediate frequency with 400 MHz bandwidth. For the Performance test we supply the 0.5 and 1.67 MHz rectangular wave, then we obtain the autocorrelation coefficients. The final results, which process by using FFT, get the almost same results compare with the theoretical correlation.

Evaluation of Effectiveness of Vacuum Oral Cleaner Developed for Patients with Limited Mobility

Lee, Jae-Hyun,Jung, Ki-Won,Kim, Hee-Kyung,Koo, Ki-Tae,Kim, Sung-Hun The Korean Dental Association 2016 대한치과의사협회지 Vol.54 No.12

Purpose : The purpose of this study was to compare the plaque removal effects of vacuum oral cleaner developed for the patients with limited mobility with those of manual toothbrushes and high pressure injection oral cleaner (dental water jet). Meterials and methods : Thirty human subjects were measured with Patient Hygiene Performance index (PHP index) and O'Leary index before and after the use of toothbrush, high pressure injection oral cleaner and vacuum oral cleaner. These three different oral hygiene methods were conducted with seven-day intermittence. Then the statistical analysis was carried out to define plaque removal rate of three different oral hygiene methods (${\alpha}=.05$). Results : According to the efficacy analysis of plaque removal before and after the oral cleaning using each of three methods, significant reduction in plaque after the treatment compared to the previous state when using toothbrush, high pressure injection oral cleaner, and vacuum oral cleaner was observed (P < 0.001). PHP index of tooth brushing was higher than that of the high pressure injection oral cleaner, while PHP index of vacuum oral cleaner did not show significant difference from either of the other two methods. There was no significance difference in O'Leary index among the three methods. Conclusion : Effect of plaque removal using the vacuum oral cleaner is comparable to that of manual tooth brush or high pressure injection oral cleaner, so it will be helpful for self-oral hygiene care of the patients with limited mobility.

Inhomogeneity correction in on-line dosimetry using transmission dose

Lee,Hyoung-Koo,Wu,Hong-Gyun,Huh,Soon-Nyung,Ha,Sung-Whan 대한방사선 방어학회 1998 방사선방어학회지 Vol.23 No.3

목적 : 환자를 통과한 투과선량ㅇ로부터 알고리즘을 이용하여 종양선량을 계산하는 새로운 개념의 온라인 선량측정시 인체조직내의 폐 등 불균질조직의 존재는 인체내 종양선량 및 투과선량에 영향을 미친다. 인체내에 불균질조직이 존재하는 경우 측정된 투과선량으로부터 종양선량 환산시 밀도를 이용한 보저의 정확도를 확인하기 위하여 실험을 시행하였다. 방법 : 폐조직의 밀도와 유사한 재질인 코르크 (밀도 0.202 gm.cm³) 팬톰 (CP)과 연부조직의 밀도와 유사한 재질인 폴리스티렌 (밀도 1.040 gm.cm³) 팬톰 (PP)을 사용하였으며 인체의 흉부와 유사한 조건에서 측정하였다. 즉 흉부에 방사선이 전후 방향에서 조사될 경우에 해당하는 팬톰은 3 cm 두께의 PP를 CP 상하에 위치하였으며 CP의 두께는 5, 10, 20 cm으로 하였다. 흉부에 방사선이 측면에서 조사되는 경우에 해당하는 팬톰은 중앙에 종격동에 해당하는 6 cm 두께의 PP를 위치하고 좌우에 10 cm 두께의 CP 을 위치하였으며 조사면의 크기는 3 ×3 내지 20 ×20 cm의 범위, 팬톰-전리함간 거리 (phantom-chamber distance, PCD) 는 10-50 cm으로 하였다. 또한 두 물질에 대한 밀도차를 이용하여 CP과 동일한 방사선 감쇄를 나타낼 것으로 예상되는 두께의 PP를 CP 대신 위치하여 동일한 방법으로 측정하여 비교하였다. 결과 : 밀도를 이용하여 보정한 CP 와 등가두께의 PP를 사용한 경우의 투과선량은 CP 을 사용한 경우에 비하여 CP 의 두께 5 cm 인 경우 4, 6, 10 MV에서 각각 평균 0.18(±0.27)%, 0.10 (±0.43)%, 0.33(±0.30)% 의 오차를 보였다. CP의 두께 10 cm 인 경우에는 에너지 별로 0.23 (±0.73)%, 0.05 (±0.57)%, and 0.04 (±0.40)%, 20 cm 인 경우에는 0.55 (±0.36)%, 0.34 (±0.27)% 0.34 (±0.18)% 의 오차를 보였다. 중간에 6 cm의 PP를 위치한 경우에는 에너지별로 1.15 (±1.86)%, 0.90 (±1.43)%, 0.86 (±1.01)% 의 오차를 나타내었다. 이경우에는 PCD 10 cm 의 경우에 비교적 큰 오차를 보였으며 PCD 10 cm 의 경우를 제외하면 에너지별로 0.47 (±1.17)%, 0.42 (±0.96)%, 0.55(±0.77)% 의 오차로 크게 감소하였다. 결론 : 방사선이 통과하는 경로에 불균질조직인 폐가 존재할 경우에도 불균질조직에 대하여 조직의 밀도를 이용하여 보정하는 방법을 사용하여 투과선량을 계산할 수 있음을 알 수 있었다. Purpose : Tissue inhomogeneity such as lung affects tumor dose as well as transmission dose in new concept of on-line dosimetry which estimates tumor dose from transmission dose using the new algorithm. This study was carried out to confirm accuracy of correction by tissue density in tumor dose estimation utilizing transmission dose. Methods : Cork phantom (CP, density 0.202 gm/cm³) having similar density with lung parendhyme and polystyrene phantom (PP, density 1,040 gm/cm³) having similar density with soft tissue were used. Dose measurement was carried out under condition simulating human chest. On simulating AP-PA irradiation, PPs with 3 cm thickness were placed above and below CP, which had thickness of 5, 10 and 29 cm. On simulating lateral irradiation, 6 cm thickness of PP was placed between two 10 cm thichness CPs additional 3 cm thick PP was placed to both lateral sidesw. 4, 6 and 10 MV x-ray were used. Field size was in the range of 3 ×3cm through 20 ×20 cm, and phantom-chamber distance (PCD) was 10 to 50 cm. Above result was compared with another sets of data with equivalent thickness of PP which was corrected by density. Result : When transmission dose of PP was compared with equivalent thickness of CP whcih was corrected with density, and average eror was 0.18 (±0.27)% for 4 MV, 0.10 (±0.43)% for 6 MV, and 0.33 (±0.30)% for 10 MV with CP having thicnknss of 5 cm. When CP was 10 cm thick, the error was 0.23 (±0.73)%, 0.05 (±0.57)%, and 0.04 (±0.40)%, while for 20 cm, error was 0.55 (±0.36)%, 0.34 (±0.27)%, and 0.34 (±0.18)% for corresponding energy. With lateral irradiation model, difference was 1.15 (±1.86)%, 0.90 (±1.43)%, and 0.86 (±1.01)% for corresponding energy. Relatively large difference was found in case of PCD having value of 10 cm. Omitting PCD with 10 cm, the difference was reduced to 0.47 (±1.17)%, 0.42 (±0.96)%, and 0.55(±0.77)% for corresponding energy. Conclusion : When tissue inhomogeneity such as lung is in fact of x-ray beam, tumor dose could be calulated from transmission dose after correction utilizing tissue density.

Fixation characteristics of micronized copper compared to copper amine preservatives

( Sung Mo Kang ),( Won Mo Koo ),( Kwon Min Kim ),( Dong Yeop Kang ),( Dong Heub Lee ),( In Aeh Kang ),( Jong Young Park ) 韓國木材工學會 2010 한국목재공학회 학술발표논문집 Vol.2010 No.-

Retinoid X Receptor α Overexpression Alleviates Mitochondrial Dysfunction-induced Insulin Resistance through Transcriptional Regulation of Insulin Receptor Substrate 1

Lee, Seung Eun,Koo, Young Do,Lee, Ji Seon,Kwak, Soo Heon,Jung, Hye Seung,Cho, Young Min,Park, Young Joo,Chung, Sung Soo,Park, Kyong Soo Korean Society for Molecular and Cellular Biology 2015 Molecules and cells Vol.38 No.4

Mitochondrial dysfunction is associated with insulin resistance and diabetes. We previously showed that retinoid X receptor ${\alpha}$ ($RXR{\alpha}$) played an important role in transcriptional regulation of oxidative phosphorylation (OXPHOS) genes in cells with mitochondrial dysfunction caused by mitochondrial DNA mutation. In this study, we investigated whether mitochondrial dysfunction induced by incubation with OXPHOS inhibitors affects insulin receptor substrate 1 (IRS1) mRNA and protein levels and whether $RXR{\alpha}$ activation or overexpression can restore IRS1 expression. Both IRS1 and $RXR{\alpha}$ protein levels were significantly reduced when C2C12 myotubes were treated with the OXPHOS complex inhibitors, rotenone and antimycin A. The addition of $RXR{\alpha}$ agonists, 9-cis retinoic acid (9cRA) and LG1506, increased IRS1 transcription and protein levels and restored mitochondrial function, which ultimately improved insulin signaling. $RXR{\alpha}$ overexpression also increased IRS1 transcription and mitochondrial function. Because $RXR{\alpha}$ overexpression, knock-down, or activation by LG1506 regulated IRS1 transcription mostly independently of mitochondrial function, it is likely that $RXR{\alpha}$ directly regulates IRS1 transcription. Consistent with the hypothesis, we showed that $RXR{\alpha}$ bound to the IRS1 promoter as a heterodimer with peroxisome proliferator-activated receptor ${\delta}$ ($PPAR{\delta}$). These results suggest that $RXR{\alpha}$ overexpression or activation alleviates insulin resistance by increasing IRS1 expression.

The Korean Academy of Tuberculosis and Respiratory Diseases : Slide Session ; OS-104 : Critical Care ; The Amount of Visceral Adipose Tissue Quantitatively Measured by Abdominal Computed Tomography Is Dose-Dependently Associated with Mortality in Patients

( Sung Jun Ko ),( Sun Mi Choi ),( Jin Woo Lee ),( Young Sik Park ),( Chang Hoon Lee ),( Jae Joon Yim ),( Chul Gyu Yoo ),( Young Whan Kim ),( Sung Koo Han ),( Sang Min Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Adipose tissue is recently recognized as not only energy reservoir but also endocrine organ producing proin ammatory cytokines. Especially the impact o visceral adipose tissue(VAT) in critical illnesses has been proposed, but researches on the association between VAT and sepsis were scarce and quantitative measurement of VAT had not been used. Methods: In this retrospective cohort study, we enrolled patients with sepsis who examined abdominal computed tomography(A-CT) within 1 month of occurrence of sepsis, among the patients admitted to intensive care unit(ICU). Age, sex, anthropometric values, comorbidities and APACHE II score were reviewed. The areas of VAT and total adipose tissue(TAT) on the section of A-CT image of the umbilicus level were measured by calculating pixels presenting fat density. Results: Among 287 patients admitted to ICU due to sepsis, 178 patients were included for this study. Median age was 65 and 59.0% were men. In-hospital mortality rate was 57.9%. Women had higher TAT and subcutaneous adipose tissue, lower VAT/TAT ratio compared to men. The amount of VAT and VAT/TAT ratio were higher in in-hospital mortality group than in survivor group(90.41cm2 vs. 63.83cm2 and 45.88% vs. 32.79%, p=0.001 and <0.001, respectively). After adjusting age, sex, APACHE II score and comorbidities, multivariate logistic regression analysis revealed that the amount of VAT and VAT/TAT ratio were independent prognostic factors of sepsis with obvious dose-dependent relationship(VAT/TAT ratio quartile 3: OR 8.832, p<0.001 and quartile 4: OR 29.477, p<0.001, compared to quartile 1 respectively). Conclusion: The amount of VAT and VAT/TAT ratio quantitatively measured by A-CT were positively correlated with mortality in sepsis, and this association was dose-dependent. Visceral obesity should be considered as the poor prognostic factor of sepsis.