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Single-Port Robotic Cholecystectomy: Early Experience from 8 Cases
( Hyung Jun Kwon ),( Horyon Kong ),( Sang Geol Kim ),( Yun Jin Hwang ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: Single-port laparoscopic cholecystectomy (SPLC) is a technical concept to reduced pain and improve cosmetic results when compared to multi-port cholecystectomy. However, SPLC is associated with technical limitation due to the enhanced complexity of the approach and limited number of specialized instruments or platforms. On the other hand, using a robotic platform may overcome these problems and enable more precise surgical actions by increasing freedom of movement and by restoring intuitive instrument control. In this presentation, we report the early clinical experience of our first 8 sing-port robotic cholecystectomy (SPRC) cases. Methods: Between November 2016 and February 2017, eight patients underwent SPRC with the da Vinci Xi robot and single-site instrumentation. We retrospectively reviewed clinical data on those patients. Results: All of 8 patients had completion of SPRC. Seven patients were female and one was male. Average patient age was 43.3±11.8 years and BMI was 22.4±1.4 kg/m2. Three patients (37.5%) were diagnosed with chronic calculous cholecystitis. Three patients (37.5%) underwent operation for polypoid lesions of the gallbladder. One patient (12.5%) was diagnosed with acute calculous cholecystitis. The mean operation time (skin-to-skin) was 83.9±30.7 min, docking time was 13.25±8.1 min, and console time was 42.1±26.4 min. The intraoperative blood loss was negligible. The mean Visual Analog Pain Scale score 6hr after the surgery was 2.9±0.4. The mean length of hospital stay average postoperative hospital stay was 2.3±1.0 day. There were no intraoperative complication and one patient developed seroma on port site. Conclusions: Robotic single-port cholecystectomy appears feasible and safe in our early experience.
Isolation and molecular identification of Vibrio harveyi from the look down fish (Selene vomer)
Jun, Jin-Woo,Lee, Young-Ran,Giri, Sib Sankar,Kim, Hyoun-Joong,Yun, Sae-Kil,Chi, Cheng,Kim, Sang-Guen,Koh, Jeong-Rack,Jung, Ji-Yun,Lee, Byeong-Chun,Park, Se-Chang The Korean Society of Veterinary Science 2016 大韓獸醫學會誌 Vol.56 No.2
Gradual mortality of look down fish (Selene vomer) was observed in a private aquarium in Seoul, showing abnormal swimming behavior and lethargy. A bacterial pathogen from kidney was cultured, identified, and confirmed as Vibrio harveyi using Vitek System 2 and 16S rRNA gene sequencing. A predominant bacterial strain, SNUVh-LW2 was proved to be most closely related to isolates from China by phylogenetic analysis with minimum evolution method. Also, tetracycline was considered as the most sensitive antibiotic agent via antibiotic susceptibility test. The group of fish was treated according to the diagnostic result and no more mortality was observed.
Lentigo maligna melanoma mimicking seborrheic keratosis
( Sang Youl Yun ),( Jun Gyu Song ),( Moo Kyu Suh ),( Jong Im Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Lentigo maligna melanoma(LMM) constitutes 10%-15% of cutaneous melanomas. LMM most commonly affects the sun-exposed skin of the elderly. It is frequently mistaken clinically for other pigmented neoplasms, which may result in a delay of diagnosis and treatment. It is the least common type of melanoma and rarely affects the Koreans. There are few reports regarding LMM in Korean literature. We report a case of lentigo maligna melanoma occurring in 72-year-old man. The patient presented with solitary, 1.0x1.0cm-sized, black colored plaque on left cheek. The lesion developed 9 months ago and recently the size has been increased. Skin biopsy specimen showed epidermal atrophy and proliferation of atypical melanocytes with hyperchromatic nuclei along the basal layer, solar elastosis, and invasion of melanocytes into the dermis. On immunohistochemical study, the tumor cells were positive for S-100 protein, HMB-45 and Ki-67. Therefore, lentigo maligna melanoma was diagnosed. He was treated with the wide excision with full thickness skin graft. The skin lesions were cured without recurrence.
A Survey of Dental Caries in Mongolia in 2014
Sung-Wook Yun,Seung-Chul Shin,Yeon-Soo Chang,Ho-Kil Kim,Sun-Joo Sohn,Jung-Kyu Kim,Soo-Jung Park,Hyun-Jun Yoo,Ja-Won Cho 대한예방치과학회 2014 International Journal of Clinical Preventive Denti Vol.10 No.3
Objective: The authors had conducted the oral health survey of Mongolian people with dual methods as direct oral examination by trained dentists and indirect method through taking the intra oral photos of the subjects by use of Nikon digital camera, in order to interpretate the image for finding the caries states of the subject people. Methods: One thousand three hundred seven persons of subject were examined in this dental survey, and classified with age distribution as 5, 9, 12, 15, 20s, 40s, and 60s years old at urban area of Ulaanbaatar area and the others at the rural areas at Bornuur as steppe area and at Mandalgovi as desert area. Results: Primary decayed tooth (dt), primary filled tooth (ft), and primary decayed, filled tooth (dft) index of Mongolian 5 years old were calculated as 6.25±4.56, 1.09±2.17, and 7.34±4.69 as high in caries incidence without treatment. Permanent decayed tooth (DT), permanent filled tooth (FT), permanent decayed, missing, filled tooth (DMFT) index of Mongolian 12 years old were as 2.37±2.76, 0.29±0.93 and 2.93±3.11, as high caries incidence without early treatment, and 12.1% of DMFT rate, 77.7% of DMF rate as the most children have been caries experienced. Conclusion: Oral health promotion and early treatment of caries in public oral health plan were recommended to promote the oral health level of Mongolian people.
Sang Min Kyu,Park Jie eun,Song Dae Kwon,Jeong Jun Yang,Hwang Hee Ju,Kim Hyun woo,Kim Tae Yun,Park So Young,Kang Se Won,Patnaik Bharat Bhusan,Cha Sung‐Jae,Han Yeon Soo,Lee Hee Il,Lee Yong Seok 한국곤충학회 2022 Entomological Research Vol.52 No.6
Ticks are vectors that cause disease by transmitting bacteria, viruses, and protozoa to humans or animals. The Asian longhorned tick Haemaphysalis longicornis, a vector of medical and veterinary importance, is widely distributed in the Korean peninsula and can transmit various pathogens including Rickettsia spp., Borrelia spp., Francisella spp., Coxiella spp., and severe fever with thrombocytopenia syndrome virus (SFTS virus). Despite the abundance and importance, studies on the microbiome of H. longicornis in Korea are limiting. Here we first report the microbiome diversity of H. longicornis in terms of region, stage, and sex. H. longicornis used in this study were collected from 16 different regions. The V3-V4 region was amplified and sequenced by MiSeq platform. The microbial diversity analysis was performed using Qiime2. A total of 1,754,418 non-chimeric reads were obtained from a total of 46 samples, and an average of 126 operational taxonomic units (OTUs) and a total of 1,398 OTUs were identified. Our results were used for H. longicornis microbial community database construction for each region that enables to identify singularities in each region.
Lee, Youn-Ri,Lee, Chang-Kwon,Park, Hyo-Jun,Kim, Hyo-Jin,Kim, Jung-Hwan,Kim, Jae-Heung,Lee, Keun-Sang,Lee, Yun-Lyul,Min, Kyung-Ok,Kim, Bo-Kyung Korean Physical Therapy Science 2006 대한물리치료과학회지 Vol.13 No.2
Vascular smooth muscle contraction is mediated by activation of extracellular signal-regulated kinase (ERK) 1/2, an isoform of mitogen-activated protein kinase (MAPK). However, the role of stress-activated protein kinase/c-Jun N-terminal kinase (JNK) in vascular smooth muscle contraction has not been defined. We investigated the role of JNK in the contractile response to norepinephrine (NE) in rat aortic smooth muscle. NE evoked contraction in a dose-dependent manner, and this effect was inhibited by the JNK inhibitor SP600125. NE increased the phosphorylation of JNK, which was greater in aortic smooth muscle from hypertensive rats than from normotensive rats. NE-induced JNK phosphorylation was significantly inhibited by SP600125 and the conventional-type PKC (cPKC) inhibitor Go6976, but not by the Rho kinase inhibitor Y27632 or the phosphatidylinositol 3-kinase inhibitor LY294002. Thymeleatoxin, a selective activator of cPKC, increased JNK phosphorylation, which was inhibited by $G{\ddot{o}}6976$. SP600125 attenuated the phosphorylation of caldesmon, an actin-binding protein whose phosphorylation is increased by NE. These results show that JNK contributes to NE-mediated contraction through phosphorylation of caldesmon in rat aortic smooth muscle, and that this effect is regulated by the PKC pathway, especially cPKC.