Cyclic behaviour of end-plate beam-to-column composite joints

Rui Simões,Luís Simões da Silva,Paulo J.S. Cruz 국제구조공학회 2001 Steel and Composite Structures, An International J Vol.1 No.3

An experimental research program on end-plate beam-to-column composite joints under cyclic loading is presented. The major focus relates to the identification of the contribution of the concrete confinement in composite columns to the behaviour of the joint, on internal nodes and external nodes, together with an assessment of degradation of strength and stiffness in successive loading cycles. From the experimental results it was possible to identify the various failure modes and to fit the corresponding hysteretic curves to the Richard-Abbott and Mazzolani models. These curve-fitting exercises highlighted the need to adapt both models, either for improved ease of application, or to deal with some aspects previously not covered by those models.

Commercial catalysts screening for the direct amination of cyclohexanol

Rui Churro,Fernando Mendes,Paulo Araújo,Luís M. Madeira,Filipa Ribeiro 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.95 No.-

Two groups of commercially available Ni- and Pd-based catalysts were used for the direct amination ofcyclohexanol (CHOL) with NH3 as aminating agent and in the presence of H2, aiming the selectiveproduction of cyclohexylamine (CHA) and aniline. The fresh catalysts were characterized in terms ofmetal loading, support composition (prevailing SiO2 and Al2O3) and metallic dispersion. Ni-basedcatalysts revealed to be highly active while Pd-based were more selective towards aniline, howeverrequiring higher temperatures and catalyst loading to reach significant CHOL conversions (from 17 up to67 %). The activity of the catalysts is intrinsically related to their metallic dispersion regardless the metalloading. The Ni-based catalyst with 46 wt. % of Ni is the most promising once it presents higher turnoverfrequency (TOF) values, as 10 fold high, particularly related to the ratio of desired to undesired by-products. Moreover, operating conditions considerably affect catalysts’ performance.

Comparison of Outcomes in Immediate ImplantBased Breast Reconstruction: Acellular Dermal Matrix versus Inferior Dermal Flap

Mata Ribeiro Luís,Meireles Rita P.,Brito Irís M.,Costa Patrícia M.,Rebelo Marco A.,Barbosa Rui F.,Choupina Miguel P.,Pinho Carlos J.,Ribeiro Matilde P. 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.2

Background Implant-based breast reconstruction has evolved tremendously in the last decades, mainly due to the development of new products and techniques that make the procedure safer and more reliable. The purpose of this study was to compare the outcomes in immediate one-stage breast reconstruction between acellular dermal matrix (ADM) and inferior dermal flap (IDF).Methods We conducted a retrospective comparative study of patients submitted to immediate breast reconstructions with an anatomical implant and ADM or IDF in a single center between 2016 and 2018. Outcomes evaluated included major complications, early complications, reinterventions, readmissions, and reconstruction failure. Simple descriptive statistics and univariate analysis were performed.Results A total of 118 breast reconstructions (85 patients) were included in the analysis. Patients in the IDF group had a higher body mass index (median = 27.0) than patients in the ADM group (median = 24). There were no statistically significant differences among both groups regarding immediate major complication, early complications, readmissions, and reinterventions.Conclusion There are no significant differences in complications between the ADM and IDF approach to immediate implant breast reconstruction. In patients with higher body mass index and large, ptotic breasts, we recommend an immediate implant reconstruction with IDF.

Comparison of Outcomes in Immediate ImplantBased Breast Reconstruction: Acellular Dermal Matrix versus Inferior Dermal Flap

Mata Ribeiro Luís,Meireles Rita P.,Brito Irís M.,Costa Patrícia M.,Rebelo Marco A.,Barbosa Rui F.,Choupina Miguel P.,Pinho Carlos J.,Ribeiro Matilde P. 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.1

Background Implant-based breast reconstruction has evolved tremendously in the last decades, mainly due to the development of new products and techniques that make the procedure safer and more reliable. The purpose of this study was to compare the outcomes in immediate one-stage breast reconstruction between acellular dermal matrix (ADM) and inferior dermal flap (IDF).Methods We conducted a retrospective comparative study of patients submitted to immediate breast reconstructions with an anatomical implant and ADM or IDF in a single center between 2016 and 2018. Outcomes evaluated included major complications, early complications, reinterventions, readmissions, and reconstruction failure. Simple descriptive statistics and univariate analysis were performed.Results A total of 118 breast reconstructions (85 patients) were included in the analysis. Patients in the IDF group had a higher body mass index (median = 27.0) than patients in the ADM group (median = 24). There were no statistically significant differences among both groups regarding immediate major complication, early complications, readmissions, and reinterventions.Conclusion There are no significant differences in complications between the ADM and IDF approach to immediate implant breast reconstruction. In patients with higher body mass index and large, ptotic breasts, we recommend an immediate implant reconstruction with IDF.

Calibration of model parameters for the cyclic response of end-plate beam-to-column steel-concrete composite joints

Pedro Nogueiro,Luís Simões da Silva,Rita Bento,Rui Simões 국제구조공학회 2009 Steel and Composite Structures, An International J Vol.9 No.1

Composite joints, considering the composite action of steel and concrete, exhibit, in general, high strength and high ductility. As a consequence, the use of this type of joint has been increasing in many countries, especially in those that are located in earthquake-prone regions. In this paper, a hysteretic model with pinching is presented that is able to reproduce the cyclic response of steel and composite joints. Secondly, the computer implementation and adaptation of the model in a spring element within the computer code. Seismosoft is described. The model is subsequently calibrated using a series of experimental test results for composite joints subjected to cyclic loading. Finally, typical parameters for the various joint configurations are proposed.

Comparative clinical and radiologic evaluation between patients undergoing standard reversed shoulder arthroplasty or bony increased offset

Tiago Amorim-Barbosa,Ana Ribau,Hélder Fonte,Luís Henrique Barros,Rui Claro 대한견주관절학회 2023 대한견주관절의학회지 Vol.26 No.1

Background: Modifications of the medialized design of Grammont-type reverse shoulder arthroplasty (RSA) using a bony increased offset (BIO-RSA) has shown better clinical results and fewer complications. The aim of this study is to compare the clinical results, complications, and radiological outcomes between patients undergoing standard RSA and BIO-RSA. Methods: A retrospective review was performed of 42 RSA procedures (22 standard RSA and 20 BIO-RSA). With a minimum of one year of follow-up, range of motion (ROM), Constant shoulder score (CSS), visual analog scale (VAS), and subjective shoulder score (SSS) were compared. Radiographs and computed tomography (CT) scan were examined for scapular notching, glenoid and humeral fixation, and graft healing. Results: At a mean follow-up of 27.6 months (range, 12–48 months), a significant difference was found for active-internal rotation (P=0.038) and for passive-external rotation (P=0.013), with better results in BIO-RSA. No other differences were found in ROM, CSS (P=0.884), VAS score, and SSS. Graft healing and viability were verified in all patients with CT scan (n=34). The notching rate was 28% in the standard RSA group and 33% in the BIO-RSA group, but the standard RSA had more severe notching (grade 2) than BIO-RSA (P=0.039). No other significative differences were found in glenoid and humeral fixation. Conclusions: Bone-graft lateralization is associated with better internal and external rotation and with less severe scapular notching compared to the standard RSA. Integration of the bone graft occurs effectively, with no relevant changes observed on radiographic evaluation. Level of evidence: Level III; Retrospective cohort design treatment study

On the Security Aspects of Internet of Things: A Systematic Literature Review

Evandro L. C. Macedo,Egberto A. R. de Oliveira,Fabio H. Silva,Rui R. Mello Jr,Felipe M. G. França,Flavia C. Delicato,José F. de Rezende,Luís F. M. de Moraes 한국통신학회 2019 Journal of communications and networks Vol.21 No.5

Internet of Things (IoT) has gained increasing visibilityamong emerging technologies and undoubtedly changing our dailylife. Its adoption is strengthened by the growth of connected devices(things) as shown in recent statistics. However, as the numberof connected things grows, responsibility related to security aspectsalso needs to increase. For instance, cyberattacks might happenif simple authentication mechanisms are not implemented on IoTapplications, or if access control mechanisms are weakly defined. Considering the relevance of the subject, we performed a systematicliterature review (SLR) to identify and synthesize security issuesin IoT discussed in scientific papers published within a periodof 8 years. Our literature review focused on four main security aspects,namely authentication, access control, data protection, andtrust. We believe that a study considering these topics has the potentialto reveal important opportunities and trends related to IoTsecurity. In particular, we aim to identify open issues and technologicaltrends that might guide future studies in this field, thusproviding useful material both to researchers and to managers anddevelopers of IoT systems. In this paper, we describe the protocoladopted to perform the SLR and present the state-of-the-art on thefield by describing the main techniques reported in the retrievedstudies. To the best of our knowledge, ours is the first study tocompile information on a comprehensive set of security aspects inIoT. Moreover, we discuss the placement, in terms of architecturaltiers, for deploying security techniques, in an attempt to provideguidelines to help design decisions of security solution developers. We summarize our results showing security trends and researchgaps that can be explored in future studies.

Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities

Sebastião van Uden,Joana Silva-Correia,Joaquim Miguel Oliveira,Rui Luís Reis 한국생체재료학회 2017 생체재료학회지 Vol.21 No.4

Background: Intervertebral disc degeneration has an annual worldwide socioeconomic impact masked as low back pain of over 70 billion euros. This disease has a high prevalence over the working age class, which raises the socioeconomic impact over the years. Acute physical trauma or prolonged intervertebral disc mistreatment triggers a biochemical negative tendency of catabolic-anabolic balance that progress to a chronic degeneration disease. Current biomedical treatments are not only ineffective in the long-run, but can also cause degeneration to spread to adjacent intervertebral discs. Regenerative strategies are desperately needed in the clinics, such as: minimal invasive nucleus pulposus or annulus fibrosus treatments, total disc replacement, and cartilaginous endplates decalcification. Main body: Herein, it is reviewed the state-of-the-art of intervertebral disc regeneration strategies from the perspective of cells, scaffolds, or constructs, including both popular and unique tissue engineering approaches. The premises for cell type and origin selection or even absence of cells is being explored. Choice of several raw materials and scaffold fabrication methods are evaluated. Extensive studies have been developed for fully regeneration of the annulus fibrosus and nucleus pulposus, together or separately, with a long set of different rationales already reported. Recent works show promising biomaterials and processing methods applied to intervertebral disc substitutive or regenerative strategies. Facing the abundance of studies presented in the literature aiming intervertebral disc regeneration it is interesting to observe how cartilaginous endplates have been extensively neglected, being this a major source of nutrients and water supply for the whole disc. Conclusion: Several innovative avenues for tackling intervertebral disc degeneration are being reported – from acellular to cellular approaches, but the cartilaginous endplates regeneration strategies remain unaddressed. Interestingly, patientspecific approaches show great promise in respecting patient anatomy and thus allow quicker translation to the clinics in the near future.

Lysosome Inhibition Reduces Basal and Nutrient-Induced Fat Accumulation in Caenorhabditis elegans

Rui Lu,Juan Chen,Fangbin Wang,Lu Wang,Jian Liu,Yan Lin 한국분자세포생물학회 2022 Molecules and cells Vol.45 No.9

A long-term energy nutritional imbalance fundamentally causes the development of obesity and associated fat accumulation. Lysosomes, as nutrient-sensing and lipophagy centers, critically control cellular lipid catabolism in response to nutrient deprivation. However, whether lysosome activity is directly involved in nutrient-induced fat accumulation remains unclear. In this study, worm fat accumulation was induced by 1 mM glucose or 0.02 mM palmitic acid supplementation. Along with the elevation of fat accumulation, lysosomal number and acidification were also increased, suggesting that lysosome activity might be correlated with nutrient-induced fat deposition in Caenorhabditis elegans. Furthermore, treatments with the lysosomal inhibitors chloroquine and leupeptin significantly reduced basal and nutrient-induced fat accumulation in C. elegans. The knockdown of hlh-30, which is a critical gene in lysosomal biogenesis, also resulted in worm fat loss. Finally, the mutation of aak-2, daf-15, and rsks-1showed that mTORC1 (mechanistic target of rapamycin complex-1) signaling mediated the effects of lysosomes on basal and nutrient-induced fat accumulation in C. elegans. Overall, this study reveals the previously undescribed role of lysosomes in overnutrition sensing, suggesting a new strategy for controlling body fat accumulation.

Occupational Cooking and Risk of Uveal Melanoma: a Meta-analysis

Ge, Yi-Rui,Tian, Nong,Lu, Yan,Wu, Yong,Hu, Qin-Rui,Huang, Zheng-Ping Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

Background: Many observational studies have assessed the possible association between occupational cooking and uveal melanoma risk, but reported results are controversial. Our goal was to evaluate the association between occupational cooking and uveal melanoma risk by conducting a meta-analysis of observational studies. Methods: PubMed, EMBASE, and Web of Science were searched through June 2012 to identify all eligible studies. The pooled odds ratio (OR) with its 95% confidence interval (95%CI) was used to evaluate this association. Either a fixed- or a random-effects model were used to calculate pooled ORs. Results: Five case-control studies involving a total of 1,199 cases and 6,927 controls were included in the meta-analysis. Overall, occupational cooking was associated with an increased risk of uveal melanoma (OR: 1.81, 95%CI 1.33-2.46, P < 0.001). Subgroup analysis by gender suggested occupational cooking was associated with increased risk of uveal melanoma in both men (OR: 2.16, 95%CI 1.06-4.40, P = 0.034) and women (OR: 1.92, 95%CI 1.19-3.10, P = 0.008). Conclusion: This meta-analysis suggests that occupational cooking is associated with an increased risk of uveal melanoma in both men and women.