http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Characterization of the Corylopsis coreana Using Molecular Markers
Mark S. Roh,Ae Kyung Lee,Ik Young Choi,Jae Yeong Kim,Young Hee Joung,Sun Ha Lee,Jeung Keun Suh 한국원예학회 2007 Horticulture, Environment, and Biotechnology Vol.48 No.3
This research was initiated to study the inter-specific relationships and intra-specific variations in the Corylopsis glabrescens complex that includes C. coreana Uyeki, C. glabrescens Franch. et Sav var. glabrescens, and C. glabrescens var. gotoana (Makino) T. Yamanaka (collectively called the C. glabrescens complex) by examining accessions collected from natural habitats, various botanical gardens, and arboreta. Randomly amplified polymorphic DNA (RAPD), single nucleotide polymorphisms in the internal transcribed spacer (ITS) region of ribosomal DNA (nrDNA-ITS region) specific for C. glabrescens Franch. et Sav., phytochrome C gene, and NADH dehydrogenase subunit 1 gene analyses were performed. The results of RAPD markers showed that accessions were clustered into three major groups; the first group consisting of C. coreana, C. glabrescens var. glabrescens, C. glabrescens var. gotoana, and C. pauciflora Siebold & Zucc.; the second group of C. sinensis Hemsl., C. veitchiana Bean, C. glandulifera Hems1., and C. spicata Siebold & Zucc, and the third group of C. sinensis Hems1’ var. calvescens Rehder & E. H. Wilson with some exceptions. C. coreana, C. glabrescens var. glabrescens, and C. glabrescens var. gotoana grouped into one major cluster. Although nrDNA-ITS region cannot be effectively used for identification of the C. glabrescens complex at the level of species, C. sinensis var. calvescens clustered separately from C. sinensis var. sinensis. C. coreana accessions collected from Korea were separated from different posterior probability populations by STRUCTURE program from C. glabrescens var. glabrescens and also from var. gotoana collected from Japan. This support the establishment of C. coreana as a separate species based on this study.
Carrier Frequency of Spinal Muscular Atrophy in a Large-scale Korean Population
Jong Eun Park,Sun Ae Yun,Eun Youn Roh,Jong Hyun Yoon,Sue Shin,Chang-Seok Ki 대한진단검사의학회 2020 Annals of Laboratory Medicine Vol.40 No.4
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by progressive proximal muscle weakness and atrophy. Given the recent introduction of gene therapies, knowledge of the SMA carrier frequency in various populations has become important for developing screening programs for this disease. In total, 1,581 anonymous DNA samples from an umbilical cord blood bank were tested for SMN1 and SMN2 gene copies using a multiplex ligation-dependent probe amplification assay. Twenty-nine of the 1,581 newborns [1.83%; 95% confidence interval (CI), 1.25–2.66%] were SMA carriers with one copy of SMN1, and no homozygous SMN1 deletion was detected. The carrier frequency in this population was estimated to be 1,834 per 100,000 (95% CI, 1,254– 2,659) or 1 in 55 (95% CI, 1/79–1/38). Our data indicate that SMA carriers are not uncommon in the Korean population and may serve as a reference for designing a population screening program in Korea.
Noh, Je-Heon,Lee, Sun-Ho,Kim, Hyun-Joong,Jeong, Wu-Jin,Kim, Min-Young,Kim, Sun-A,Roh, Ji-Ae,Bae, Young-Chun,Kim, Bo-Hyun Korean AcupunctureMoxibustion Medicine Society 2018 대한침구의학회지 Vol.35 No.2
Background: Length of hospitalization for patients with lower back pain sustained in road traffic accidents was assessed clinically. Methods: In total, 170 patients with lower back pain injury sustained in road traffic accidents, were included in the study. They were divided into 2 groups: Group A with a shorter hospitalization period (1-7 days) and Group B with a longer hospitalization period (8-14 days). Each group was treated daily with traditional Korean medicine including: acupuncture, herbal acupuncture, herbal decoction medicine, and chuna treatment. To compare the treatment effects between the 2 groups, health-related quality of life, Oswestry disability index, and numeric rating scale were used. Statistical analysis between the 2 groups was assessed using Chi-square test, independent t test, and paired t test. Results: After hospitalization, Group A and Group B both showed a significant increase in their health-related quality of life scores and significant decreases in Oswestry disability index and numeric rating scale scores. In addition, Group B, with a longer hospitalization period than Group A, showed a significant improvement over Group A in its health-related quality of life and numeric rating scale scores. Conclusion: This study suggests that control of pain caused by lower back injury sustained in a road traffic accident, may be more effectively achieved in patients receiving 8-14 days of hospitalization and traditional Korean medicine treatment, compared to those receiving < 7 days of hospitalization treatment. In the future, more systematic and large-scale studies are needed to ascertain the effects of other variables.
( Hee Su Kim ),( Ji Hee Kim ),( Hong Sun Jang ),( Byung Ho Oh ),( Mi Ryung Roh ),( Kyoung Ae Nam ),( Kee Yang Chung ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Mohs mircographic surgery (MMS), firstly developed by Dr. Frederic E. Mohs in 1938, is microscopically controlled surgery for skin cancers such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma in situ. The goal of MMS is to remove a skin cancer completely with free margins at the circumferential peripheral and deep tissues during the surgery. It allows higher cure rate and with minimal surgical defect. Today, MMS has been accepted as the most effective method for removing BCC and SCC, the two most common skin cancers in Caucasians. Objectives: Study about MMS in Korea has not been investigated in depth due to its low prevalence and the difficulty in processing during the MMS. Methods: We herein report the analysis of 1000 MMS cases experienced in Severance hospital since July, 2000. Results: The mean-age of patients was 63 and the ratio of female to male was 1:1. By the diagnosis, 649 of 1000 cases (65%) was BCC and SCC, EMPD, DFSP, and Melanoma were followed by 15%, 6%, 5%, and 2%, respectively. Additionally, 72 of 1000 MMS cases (7%) were applied to various conditions including chondroid syringoma, malignant proliferating trichillemal tumor, angiosarcoma and atypical fibroxanthoma. The recurrence rate of main non-melanoma skin cancers, BCC, SCC, DFSP, and EMPD was 0.3%, 2.6%, 3.7%, and 8.4%, respectively. Conclusion: Conclusively, the cure rate of MMS is superior to other surgical modalities and MMS can be expanded to various skin tumors.