http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Molecular Analysis of TGF-β1-induced BAFF Promoter Activity in Mouse Antigen Presenting Cells
Hyun A Kim,Goo Young Seo,Hwa Joung Lee,Jae Bong Park,Pyeung Hyeun Kim 한국유전학회 2007 Genes & Genomics Vol.29 No.4
BAFF, one of the TNF ligand family, is primarily expressed by APCs such as macrophages and dendritic cells. This molecule is known to stimulate proliferation, differentiation, survival, and Ig production of B cells. In the present study, we aimed to elucidate the molecular mechanisms by which TGF-β1 induce BAFF expression in order to gain a clue if TGF-β1 may regulate B cell differentiation through influencing APCs. We found that TGF-β1 potentiates mouse dendritic cells to express BAFF and that a typical TGF-β signaling pathway is involved. Thus, Smad3 and Smad4 promoted BAFF promoter activity in mouse dendritic cells and macrophages. Further, from the analysis of the BAFF mutated promoters, we identified three putative Smad binding elements (SBEs) where Smad3 actually binds. These elements were indispensable for the promoter activity.
The PKA/CREB pathway is closely involved in VEGF expression in mouse macrophages /
Jeon, Seong Hyun,Chae, Byung Chul,Kim, Hyun A,Seo, Goo Young,Seo, Dong Wan,Chun, Gie Taek,Yie, Se Won,Eom, Seok Hyun,Kim, Pyeung Hyeun Korean Society for Molecular and Cellular Biology 2007 Molecules and cells Vol.23 No.1
cDNA Cloning and Expression of Human Rotavirus Outer Capsid Protein VP7 in Insect Cells
( Du Kyung Kang,Ki Wan Kim,Pyeung Hyun Kim,Seung Yong Seoung,Yong Hee Kim,Ick Chan Kwon,Seo Young Jeong,Eui Yeol Choi,Kyung Mee Lee,Hyun Sook Kim,Eui Chong Kim,Sai Ick Joo,Jai Myung Yang ) 한국미생물생명공학회 1998 Journal of microbiology and biotechnology Vol.8 No.4