Bilateral salpingectomy to reduce the risk of ovarian/ fallopian/peritoneal cancer in women at average risk: a position statement of the Korean Society of Obstetrics and Gynecology (KSOG)

( Miseon Kim ),( Young-han Kim ),( Yong Beom Kim ),( Jayeon Kim ),( Jae-weon Kim ),( Mi Hye Park ),( Joo Hyun Park ),( Jeong Ho Rhee ),( Myong Cheol Lim ),( Joon-seok Hong ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.5

Based on the current understanding of a preventive effect of bilateral salpingectomy on ovarian/fallopian/peritoneal cancers, the Korean Society of Obstetrics and Gynecology, Korean Society of Gynecologic Endocrinology, Korean Society of Gynecologic Oncology, Korean Society of Maternal Fetal Medicine, and Korean Society for Reproductive Medicine support the following recommendations: · Women scheduled for hysterectomy for benign gynecologic disease should be informed that bilateral salpingectomy reduces the risk of ovarian/fallopian/peritoneal cancer, and they should be counseled regarding this procedure at the time of hysterectomy. · Although salpingectomy is generally considered as a safe procedure in terms of preserving ovarian reserve, there is a lack of evidences representing its long-term outcomes. Therefore, patients should be informed about the minimal potential of this procedure for decreasing ovarian reserve. · Prophylactic salpingectomy during vaginal hysterectomy is favorable in terms of prevention of ovarian/fallopian/ peritoneal cancer, although operation-related complications minimally increase with this procedure, compared to the complications associated with vaginal hysterectomy alone. Conversion to open or laparoscopic approach from vaginal approach to perform prophylactic salpingectomy is not recommended. · Women who desire permanent sterilization at the time of cesarean delivery could be counseled for prophylactic salpingectomy before surgery on an individual basis.

Application of open water integrated multi-trophic aquaculture to intensive monoculture: A review of the current status and challenges in Korea

Park, Miseon,Shin, Sook Kyung,Do, Yong Hyun,Yarish, Charles,Kim, Jang Kyun Elsevier 2018 Aquaculture Vol.497 No.-

<P><B>Abstract</B></P> <P>Intensive fish aquaculture has raised serious environmental concerns, including eutrophication, harmful algal blooms, fish kills, etc. Integrated multi-trophic aquaculture (IMTA) may be the most suitable aquaculture technology to achieve environmental and economic sustainability. The objectives of present study are to review the status of aquaculture and IMTA in Korea; and to determine the challenges to apply the principles of IMTA to intensive monoculture in Korean coastal waters. Korea has been one of the leading countries in aquaculture. Like other advanced countries in aquaculture, such as China and Japan, most aquaculture practices in Korea are intensive monoculture and farms are highly concentrated in bays or estuaries with restricted circulation. In intensive open water aquaculture in these waters, nutrient producers (finfish) are cultured mostly in southeastern Korea whereas extractive organisms (seaweeds) are farmed in the southwestern Korea. There are relatively small areas of overlap between these monocultures, causing environmental issues and reduction in the quality of aquacultured products. Recent attempts of IMTA in Korean coastal waters suggest that IMTA can be a good management tool for improving Korean aquaculture although there are still challenges to overcome. These challenges include development of temperature tolerant species/strains of extractive organisms such as seaweeds and sea cucumbers. Most aquacultured seaweed and sea cucumber species in Korea do not grow well during the summer months, when the release of finfish effluent is at its peak. It is essential to the future success of aquaculture in Korea that a coastal zone management (CZM) be developed that reflects coordinating fed and extractive organisms in coastal bays and estuaries rather them keeping them isolated from one another. The importance of a new regulatory framework advocating IMTA solutions will be essential for environmental protection and continued success of aquaculture in Korea. Although this review is a case study in Korea for IMTA, it will also provide critical information for coastal managers, aquaculturists and regulators in other countries where there are intensive monocultures of fed and extractive organisms.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Most aquaculture practices in Korea are intensive monoculture and farms are condensed, causing environmental problems </LI> <LI> IMTA can be a good tool for Korean intensive aquaculture to increase sustainability and lessen the impact on environment </LI> <LI> To succeed open water IMTA in Korea, a new regulatory framework is required, providing incentives for IMTA adaptors </LI> <LI> High temperature tolerant species/strains of extractive organisms are needed in light of global climatic change </LI> </UL> </P>

Shape recovery characteristics of shape memory epoxy composites reinforced with chopped carbon fibers

Miseon Park,Yeontae Kim,Jin Ok Hwang,Jong Kyoo Park 한국탄소학회 2019 Carbon Letters Vol.29 No.3

Epoxy resin, which demonstrates a shape memory effect, is reinforced by chopped carbon fibers (CCFs) to improve the thermal and mechanical properties. The interfacial interactions between 2-mm-long CCFs and epoxy make an impact on not only molecular motion but also the physical behaviors of CCFs/epoxy composites. In particular, shape recovery ability of CCFs/epoxy composites is enhanced with an increase in thermal conductivity generated by crossing CCFs in the epoxy system, although CCFs/epoxy composites containing small amounts of CCFs, such as 1 or 3 phr (parts per hundred rubber), show slower recovery rates than those of raw epoxy specimens due to the difficulty of making heat bridges in composites. With these results, it is confirmed that for specific time-dependent purpose, the shape recovery vector of CCFs/epoxy can be controlled using the amount of CCFs.

Estrogen Regulates the Expression of Aminoacyl-tRNA-Synthetase-Interacting Multifunctional Protein-1 (Aimp1) in the Mouse Uterus

Miseon Park,Eun Jin Lim,Si-jeong Bea,Eunhye Kim,Young-eun Lee,Dong Ryul Lee,Youngsok Choi 한국동물생명공학회(구 한국동물번식학회) 2014 한국동물번식학회 한중일 심포지엄 Vol.2014 No.1

Aimp1 is known as a multifunctional cytokine in various cellular events. Recent study showed Aimp1 is localized in glandular epithelial, endothelial, and stromal cells in functionalis and basalis layers of the endometrium. However, the regulatory mechanism of Aimp1 in the uterus remains unknown. In the present study, we found that Aimp1 is expressed in the mouse uterus. Aimp1 transcripts were decreased at diestrus stage. However, the level of Aimp1 protein was significantly increased in the luminal epithelium in the uterine endometrium at the estrus stage during the estrous cycle. In addition, we found that the treatment of estrogen increased the expression of Aimp1 in the uterus. The treatment of estrogen increased Aimp1 expression in the uterus of ovarectomized mice. We identified one estrogen receptor binding element (ERE) on the mouse Aimp1 promoter. The activity of Aimp1 promoter was increased with estrogen treatment. Our findings indicate that Aimp1 might act as an important regulator to remodel the uterine endometrium and its expression might be regulated by estrogen during the estrous cycle. This will give us better understanding the dynamic change of uterine remodeling during the estrous cycle.

Social Mix Policy : Lessons from Experiences in United States

MiSeon Park(박미선) 韓國住宅學會 2010 주택연구 Vol.18 No.3

주택분야에서의 사회통합 (social mix) 개념은 19세기 후반에 등장하여 20세기, 21세기를 거치며 여러나라에서 적용되며 발전해 왔다. 본 연구는 사회통합정책의 기원 및 개념, 종류, 달성하고자 하는 목적 및 문제점을 미국의 사례를 통해 살펴보았다. 저자는 사회통합정책을 크게 세가지로 구분하고 (지역중심 접근, 주민중심 접근, 그리고 신규개발 방식), 개인차원, 지역사회차원, 저렴한 주택 공급능력이라는 기준을 통해 각각의 접근방식을 평가하였다. 지역중심 접근은 지역사회의 주거환경개선에 기여하고, 주민중심 접근은 개개인의 주거만족도를 증진시키며 신규개발 접근방식은 저렴 주택공급에서 우위를 점하는 것으로 나타났다. 반면 상이한 소득계층간 소통 부족문제, 사회적 관계망 형성 부족, 임대주택 재고 감소, 낮은 원주민 재정착률, 지역사회의 반감 등의 문제점이 지적되었고 이러한 문제는 한국에서의 경험과도 크게 상이하지 않음을 알 수 있었다. 이러한 문제의 근저에는 사업활성화를 위한 정부의 규제완화, 까다로운 입주자 선정기준, 소통의 장이 될 수 있는 물리적 공간 및 공통관심사 부족, 그리고 정책 입안가와 정책 수혜자 간의 다른 기대수준이 자리잡고 있었다. 이를 바탕으로 한국 사회통합 정책에 대한 시사점을 제시하였다. Social mix in housing has gained popularity since it has been regarded as a remedy for addressing poverty concentration and subsequent social problems. This article investigates the origin, evolution, and performance of social mix policy in the United States in order to draw implications for Korean housing policy. The author identifies three types of social mix: place­based, people­based, and regulations approach. These approaches are evaluated in terms of individual benefits, neighborhood outcomes, and provision of affordable housing. A people­based approach has shown better performance to benefit individual level; a place­based approach has contributed to an increase in neighborhood outcomes; a regulation approach has accomplished to the production of affordable housing. However, implementing a social mix policy entails several issues such as low rate of returnees, reduction of public housing, low level of social interaction, and neighborhood resistance. These problems were caused by the elimination of regulatory requirements, discrepancy between planners and residents, and lack of physical and social venues to incorporate different social groups. Investing underlying causes of unintended consequences sheds light on the importance of government role, understanding residents’ needs, and the significance of design and shared interests among residents.

Identification and Characterization of LHX8 DNA Binding Elements

Park Miree,Jeon Sanghyun,Jeong Ji-Hye,Park Miseon,Lee Dong-Ryul,Yoon Tae Ki,Choi Dong Hee,Choi Youngsok 한국발생생물학회 2012 발생과 생식 Vol.16 No.4

Lhx8 (LIM homeobox 8) gene encodes a LIM homeodomain transcriptional regulator that is preferentially expressed in germ cells and critical for mammalian folliculogenesis. However, Lhx8 DNA binding sequences are not characterized yet. We aimed to identify and characterize a cis-acting sequence of germ-cell specific transcriptional factor, Lhx8. To identify Lhx8 DNA binding element, Cyclic Amplification of Sequence Target (CAST) Analysis was performed. Electrophoretic Mobility Shift Assay (EMSA) was processed for the binding specificity of Lhx8. Luciferase assay was for the transcriptional activity of Lhx8 through identified DNA binding site. We identified a putative cis-acting sequence, TGATTG as Lhx8 DNA binding element (LBE). In addition, Lhx8 binds to the LBE with high affinity and augments transcriptional activity of luciferase reporter driven by artificial promoter containing the Lhx8 binding element. These findings indicate that Lhx8 directly regulates the transcription of genes containing Lhx8 binding element in oocytes during early folliculogenesis.

Korea's traditional color

MiSeon PARK 한국색채학회 2014 International Invitation Exhibition of Color Works Vol.2014 No.-

생태통합양식 기술 개발 및 미래 발전방향

박미선(Miseon PARK),양용수(Yongsu YANG),도용현(Yonghyun Do),이동길(Donggil LEE) 한국수산해양교육학회 2016 水産海洋敎育硏究 Vol.28 No.5

주거정책과 지방분권

박미선(Miseon Park) 한국지역개발학회 2020 한국지역개발학회 학술대회 Vol.2020 No.10

미국 주택바우처 프로그램의 저소득층 주거안정성과와 정책적 시사점

박미선(Miseon Park) 한국도시행정학회 2012 도시 행정 학보 Vol.25 No.2

This study aims to analyze and synthesize Housing Choice Voucher Program’s performance on low-income households in three aspects: individual, neighborhood, and operational outcomes. First of all, voucher program has a strict income target: extremely low-income households are most eligible for participating in the program. As a result, the majority of recipients consist of the underserved and vulnerable households such as extremely low-income, female-headed households, and disabled households. Second, in terms of neighborhood effect, the program has provided residential choice of recipients, which helps the underprivileged live out of poverty-stricken and minority-concentrated neighborhoods. However, neighborhood effects have tended to differ by race and ethnicity. Finally, over 25,000 public housing authorities have been responsible to administer the voucher program. Due to the cash-limit characteristics, the voucher program has burdened government with endless budget assignment, requiring relatively large amount of administrative fee. The study shows that the Housing Choice Voucher Program has contributed to relieving housing cost burden for low-income participants, and has also operated Family Self-sufficient program to help recipients get out of poverty. Based on the findings, the author provides several policy implications for Korean rental subsidy program which will introduce in the near future.