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      • KCI등재

        Making cheese with caprifig sap in Apulia, Italy: possible rebirth of an ancient tradition

        Michele Faccia,Daniele Apruzzese,Pierluigi Passaro 한국식품연구원 2019 Journal of Ethnic Foods Vol.6 No.-

        Background and objectives: Making cheese by coagulating milk with extracts or parts of plants is a tradition of many countries facing the Mediterranean basin. Such cheeses were historically produced from sheep and goat milk and represent an important cultural heritage. In the European Union (EU), nowadays, their production is allowed only after legal validation of the manufacturing process under the hygienic point of view. Unfortunately, validation has been possible only for a few Protected Designation of Origin cheeses, but other dairy products exist for which it has not been carried out. It is the case of the caprifig sap cheeses produced in the “Murgia” highplain, Apulia region, Southern Italy. In this rural marginal area, three cheeses have been historically made by this coagulant: milk sap ricotta, Pampanella, and Cacioricotta. Due to the above legal concerns, they have become very rare and, if no action is taken, they will disappear very soon. The main purpose of the present work was to make a survey about the status of preservation of their processing methods and to document them before it is too late. A second aim was to perform a first summary investigation about their safety and compositional and sensory characteristics. Methods: A series of face-to-face interviews was conducted to owners and cheesemakers of sheep and goat farms laying in the Murgia Hills territory. Cheese samples were prepared at three different rural dairies and subjected to chemical, microbiological, and sensory analyses. Results and conclusions: The survey confirmed that caprifig sap cheeses are still occasionally produced for family consumption, mainly from goat milk in the southern part of the highplain. They have the common characteristic of deriving from milk subjected to strong heat treatment and containing both casein and whey proteins. The manufacturing procedures were observed, and two different methods of preparing and using caprifig sap were documented. The cheesemaking process was analyzed and discussed under a technological point of view, and geo-sociological connections were hypothesized. The three cheeses presented significant sensory differences and proved to potentially match the EU hygienic standards if the post-vat operations are performed under correct conditions. Overall, the study gave a contribution for the hygienic validation of the manufacturing process in view of a possible rebirth.

      • RANS simulation of secondary flows in a low pressure turbine cascade: Influence of inlet boundary layer profile

        Michele, Errante,Andrea, Ferrero,Francesco, Larocca Techno-Press 2022 Advances in aircraft and spacecraft science Vol.9 No.5

        Secondary flows have a huge impact on losses generation in modern low pressure gas turbines (LPTs). At design point, the interaction of the blade profile with the end-wall boundary layer is responsible for up to 40% of total losses. Therefore, predicting accurately the end-wall flow field in a LPT is extremely important in the industrial design phase. Since the inlet boundary layer profile is one of the factors which most affects the evolution of secondary flows, the first main objective of the present work is to investigate the impact of two different inlet conditions on the end-wall flow field of the T106A, a well known LPT cascade. The first condition, labeled in the paper as C1, is represented by uniform conditions at the inlet plane and the second, C2, by a flow characterized by a defined inlet boundary layer profile. The code used for the simulations is based on the Discontinuous Galerkin (DG) formulation and solves the Reynolds-averaged Navier-Stokes (RANS) equations coupled with the Spalart Allmaras turbulence model. Secondly, this work aims at estimating the influence of viscosity and turbulence on the T106A end-wall flow field. In order to do so, RANS results are compared with those obtained from an inviscid simulation with a prescribed inlet total pressure profile, which mimics a boundary layer. A comparison between C1 and C2 results highlights an influence of secondary flows on the flow field up to a significant distance from the end-wall. In particular, the C2 end-wall flow field appears to be characterized by greater over turning and under turning angles and higher total pressure losses. Furthermore, the C2 simulated flow field shows good agreement with experimental and numerical data available in literature. The C2 and inviscid Euler computed flow fields, although globally comparable, present evident differences. The cascade passage simulated with inviscid flow is mainly dominated by a single large and homogeneous vortex structure, less stretched in the spanwise direction and closer to the end-wall than vortical structures computed by compressible flow simulation. It is reasonable, then, asserting that for the chosen test case a great part of the secondary flows details is strongly dependent on viscous phenomena and turbulence.

      • KCI등재
      • KCI등재

        Immunostaining patterns reveal potential morphogenetic role of Toll-like receptors 4 and 7 in the development of mouse respiratory system, liver and pancreas

        Michele Sommariva,Marco Busnelli,Elena Menegola,Francesca Di Renzo,Serena Indino,Alessandra Menon,Isabella Barajon,Francesca Arnaboldi 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.2

        Toll-like receptors (TLRs) are the mammalian ortholog of Drosophila melanogaster protein Toll, originallyidentified for its involvement in embryonic development. In mammals, TLRs are mainly known for their ability to recognize pathogen- or damage-associated molecular patterns and, consequently, to initiate the immune response. However, it is becoming clear that TLRs can play a role also in mammal embryo development. We have previously described TLR4 and TLR7 expression in developing mouse peripheral nervous system and gastrointestinal tract. In the present study, we extended the investigation of TLR4 and TLR7 to the respiratory system and to the two main accessory organs of the digestive system, the liver and pancreas. TLR4 and TLR7 immunostaining was performed on mouse conceptuses collected at different stages, from E12 to E18. TLR4 and TLR7 immunoreactivity was evident in the embryo pancreas and liver at E12, while, in therespiratory apparatus, appeared at E14 and E17, respectively. Although further studies are required to elucidate the specific role of these TLRs in embryo development, the differential spatiotemporal TLR4 and TLR7 appearance may suggest that TLR expression in developing embryos is highly regulated for a possible their direct involvement in the formation of the organs and in the acquisition of immune-related features in preparation for the birth.

      • KCI등재

        Cyclic presentations of groups and cyclicbranched coverings of (1,1)-knots

        Michele Mulazzani 대한수학회 2003 대한수학회보 Vol.40 No.1

        In this paper we study the connections between cyclicpresentations of groups and cyclic branched coverings of (1,1)-knots. In particular, we prove that every n-oldstrongly-cyclic branched covering of a (1,1)-knot admits acyclic presentation for the fundamental group encoded by aHeegaard diagram of genus n.

      • KCI등재

        Biolite: A Patented Ultra-Low-Level Laser-Therapy Device for Treating Musculoskeletal Pain and Associated Impairments

        Michele Gallamini,Giovanni D’Angelo,Gabriele Belloni 사단법인약침학회 2015 Journal of Acupuncture & Meridian Studies Vol.8 No.4

        After an excursus on state-of-the-art knowledge for low-level laser therapy (LLLT), Biolite, a patented ultra-low-level laser therapy device used to treat musculoskeletal pain and associated impairments, is presented. The application protocols include short stimulation of sequences of acupuncture points. The observed effects seem, however, to be far from those that might be expected after acupuncture. The primary effect seems more likely to be an extracellular soft-tissue matrix reaction. The development of the technique, the studies performed, and the evidence collected over > 10 years suggest that specifically modulated laser light can interact with human tissues at light fluences well under those previously considered as being capable of having any effect. Musculoskeletal pain very often becomes an autonomous dysfunction that is independent of the original injury and that can be effectively treated using specific peripheral acupuncture-like stimulation. Because such acupuncture is capable of reducing motor control “interferences” from noxious stimuli, it can improve motor control performance, thereby reducing the risk of falls in the elderly individuals. The proposal of acupuncture-derived protocols to be applied by Western physiotherapists using an ultra-low-level laser therapy device is a further “bridge” between two different, and sometimes very different, clinical worlds to better serve our patients.

      • How Does Prior Information Affect Analyst Forecast Herding?

        Michele O'Neill,Minsup Song,Judith Swisher 한국재무학회 2008 한국재무학회 학술대회 Vol.2008 No.05

        This research uses four different measures of bold to investigate how prior information affects analyst herding decisions. Results for the more restrictive measures of bold suggest that the probability of herding is greater with large information shocks. Evidence also shows that analysts are more likely to herd in their forecast revisions when their current outstanding forecasts deviate more from the consensus mean and in the presence of strong observable signals. In general, analysts with current outstanding forecasts that are optimistic are more likely to issue revised forecasts that are also optimistic.

      • KCI등재

        A Critical Review of Port Pricing Literature : What Role for Academic Research?

        Michele ACCIARO 한국해운물류학회 2013 The Asian journal of shipping and Logistics Vol.29 No.2

        Few topics in the area of port economics have attracted so much attention from the side of the academic community as port pricing. The impact of such literature has been quite tangible in terms of policy development and the adoption of cost-based charging practices by many ports. Nonetheless as the port sector changes, new areas of research emerge and the academic community needs to look beyond the traditional theories to provide research that matters. This manuscript provides a review of the existing literature on port pricing with a specific focus on the literature of the last decade. In the paper the author carried out a systematic analysis of the main maritime and port economics journals and highlighted the current literature gaps and the areas that can benefit from academic attentions. Among the most interesting ones there are charging practices aiming at reducing externalities, the development of all inclusive port charges and the application of revenue management for port infrastructure utilization.

      • The combined use of computer-guided, minimally invasive, flapless corticotomy and clear aligners as a novel approach to moderate crowding

        Michele Cassetta,Federica Altieri,Stefano Pandolfi,Matteo Giansanti 대한치과교정학회 2017 대한치과교정학회지 Vol.47 No.2

        The aim of this case report was to describe an innovative orthodontic treatment method that combined surgical and orthodontic techniques. The novel method was used to achieve a positive result in a case of moderate crowding by employing a computer-guided piezocision procedure followed by the use of clear aligners. A 23-year-old woman had a malocclusion with moderate crowding. Her periodontal indices, oral health-related quality of life (OHRQoL), and treatment time were evaluated. The treatment included interproximal corticotomy cuts extending through the entire thickness of the cortical layer, without a fullthickness flap reflection. This was achieved with a three-dimensionally printed surgical guide using computer-aided design and computer-aided manufacturing. Orthodontic force was applied to the teeth immediately after surgery by using clear appliances for better control of tooth movement. The total treatment time was 8 months. The periodontal indices improved after crowding correction, but the oral health impact profile showed a slight deterioration of OHRQoL during the 3 days following surgery. At the 2-year retention follow-up, the stability of treatment was excellent. The reduction in surgical time and patient discomfort, increased periodontal safety and patient acceptability, and accurate control of orthodontic movement without the risk of losing anchorage may encourage the use of this combined technique in appropriate cases.

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